專利名稱：肺血栓栓塞癥相關基因及其應用的制作方法
技術領域：
本發(fā)明屬于分子生物技術領域，更具體地，本發(fā)明涉及一組與人類肺血栓栓塞癥有關的基因及其應用。
背景技術：
肺栓塞是指全身靜脈系統(tǒng)內(nèi)的栓子游離后堵塞肺血管床，其中99％的栓子是血栓性質(zhì)的，也稱為肺血栓栓塞癥(pulmonarythromboembolism PTE)，其栓子90％來源于腹腔和下肢血栓形成。目前，人們普遍認為肺栓塞和深靜脈血栓形成是一個疾病的兩個不同階段。到目前為止，西方僅少數(shù)幾個國家報道了群體研究中深靜脈血栓形成和肺動脈血栓栓塞的估計發(fā)病率。在西方國家，總?cè)巳荷铎o脈血栓形成和肺動脈血栓栓塞的年發(fā)病率超過10萬例，幾乎與心肌梗死一樣常見。ICOPER多中心臨床試驗研究證實，發(fā)病率有明顯升高趨勢。盡管我國肺栓塞缺少大規(guī)模的流行病學研究，但診斷例數(shù)報道在逐年大幅升高。
肺栓塞的臨床表現(xiàn)呈多樣化，較為復雜，肺栓塞患者的11％在發(fā)病1小時內(nèi)死亡，特別是發(fā)生在術后并非鮮見，在臨床中發(fā)現(xiàn)同樣的手術并非都發(fā)生肺栓塞，僅為其中一部分。因此，歐美國家對不同危險因素和不同手術創(chuàng)傷采用了預防措施，包括藥物預防和機械預防，即便如此，仍有發(fā)生肺栓塞，同時大面積預防缺少個體的特異性，也是資源的浪費。80％的肺栓塞患者是發(fā)生在30％的特定人群，因此在同樣外部環(huán)境和創(chuàng)傷條件下，其內(nèi)部因素的研究十分必要。
近年來，眾多學者提出了肺栓塞和深靜脈血栓形成是由于遺傳和/或環(huán)境異常造成的一種多基因/多因素疾病。人體中存在大量的基因突變，基因多態(tài)性、基因差異表達與之有關。凝血因子V基因Leiden突變、凝血酶原基因G20210A突變、活性蛋白C抵抗、蛋白C基因缺陷蛋白、蛋白S基因缺陷、抗凝血酶III基因突變、纖溶酶原遺傳缺陷、纖溶酶原激活抑制物基因多態(tài)性、基因多態(tài)性所致高同型半胱氨酸血癥、抗磷脂抗體綜合癥、血管緊張素轉(zhuǎn)換酶(ACE)基因插入/缺失多態(tài)性等可能與肺栓塞發(fā)生發(fā)展有關。在我國由于對肺栓塞的認識起步較晚，致使我國肺栓塞的診斷、治療、預防水平尚落后，大量國民因此病致傷、致殘、死亡，特別是手術后發(fā)生的致死性肺栓塞患者屢見不鮮。因此，研究檢測肺栓塞及深靜脈血栓形成相關基因篩查的意義在于可以提供一種早期基因診斷的方法、可以深入探索肺栓塞和深靜脈血栓形成的遺傳機制，降低肺栓塞的發(fā)生率，死亡率，意義重大。
基因芯片技術是一種高新的分子生物學技術。其基本原理是將大量核酸分子固定于支持物上，然后與標記的樣品進行雜交，通過檢測雜交信號的強弱進而判斷樣品中靶分子的數(shù)量。基因芯片已經(jīng)被利用于探索和發(fā)現(xiàn)致病相關基因。
本發(fā)明是通過利用基因芯片技術實現(xiàn)本發(fā)明的目的。

發(fā)明內(nèi)容
本發(fā)明的目的是提供一組與肺血栓栓塞癥有關的相關基因，本發(fā)明另一個目的是上述相關基因在制備肺血栓栓塞癥的診斷試劑盒中的應用。
本發(fā)明是通過利用基因芯片技術篩選出與肺血栓栓塞癥有關的相關基因，以實現(xiàn)本發(fā)明目的。具體步驟為(1)研究對象的選擇隨機收集臨床影像學確定診斷的肺栓塞患者以及正常健康對照者，分為2組，男∶女＝1∶1(2)樣本準備采集研究對象外周血，離心處理后，抽提粒細胞中總RNA，從純化的總RNA中分離出mRNA。
(3)探針制備本實驗采用mRNA逆轉(zhuǎn)錄成cDNA，然后在T7 RNA聚合酶作用下以cDNA第二鏈為模版，以含有CyDye標記的CTP和無標記NTPs的核苷酸為底物，合成帶有CyDye標記的cRNA。實驗分別合成帶Cy5和Cy3的熒光探針。
(4)基因芯片的準備本實驗采用美國Agilent公司的人類全基因組寡核苷酸芯片，芯片進行常規(guī)處理，芯片常規(guī)處理的方法根據(jù)Agilent芯片使用手冊(Agilent low RNA input fluorescent linearamplification kit protocol)。
(5)芯片雜交及處理取出經(jīng)定量的Cy3和Cy5標記的熒光樣品探針雜交于基因芯片上，雜交后經(jīng)洗滌芯片等處理，立即進行掃描。
(6)數(shù)據(jù)處理及分析圖像掃描、數(shù)據(jù)讀取、分析、標準化處理、Ratio分析、cluster軟件聚類分析結果。
(7)找出肺栓塞相關基因通過綜合分析找出肺栓塞相關基因。
下面結合實施例具體闡述本發(fā)明內(nèi)容隨機收集肺栓塞病人9例，正常健康對照者20例，男∶女＝1∶1，各抽取2ml靜脈血，EDTA抗凝。
將20例正常對照的血樣各取100μl混合，用trizol法抽提得到RNA；9例肺栓塞病人血樣分別用trizol法抽提得到RNA。經(jīng)檢測確認RNA質(zhì)量合格后，進行標記雜交實驗。
實驗標記方法采用Ambion線性放大(Ambion_MessageAmpTMIIaRNA Kit)和Agilent后標記方法相結合，其中病例組RNA采用cy3熒光標記，對照組RNA采用熒光cy5標記。Cy3探針取80pmol，cy5探針取40pmol進行雜交，雜交方法采用60℃，16小時滾動雜交，并在室溫洗片。所用芯片為Agilent人全基因組oligo芯片，芯片產(chǎn)品目錄號為G4112A。
芯片結果采用Agilent掃描儀進行掃描，Imagene軟件讀取數(shù)據(jù)Scan resolution 10μm，PMT 70％，最后采用Feature Extration進行Normalize處理分析，得到ratio值(cy3/cy5)即實驗組/對照組，比較兩組的差異。即實驗組/對照組。
9例病人的結果進行聚類分析，根據(jù)統(tǒng)計分析原理，使用genespring和cluster分析軟件，對具有相同統(tǒng)計行為的多個基因進行歸類的分析方法，歸為一個簇的基因在功能上可能相似或關聯(lián)。在聚類分析后9例病人變化趨勢相同的基因中，根據(jù)GO分類結合肺栓塞的發(fā)病原理，差異基因篩選標準為肺栓塞組與對照組相比較，凡是與血栓形成有關的凝血、纖溶發(fā)生上調(diào)或下調(diào)變化的基因均入選。
表一，通過對肺栓塞患者發(fā)病期的外周血與正常人外周血的表達譜實驗分析，通過cluster聚類以及GO分類信息找出在9例患者中變化趨勢相同的基因，并根據(jù)本說明書差異基因篩選標準，從中篩選出與肺血栓栓塞癥相關基因142個，所述基因在美國國立生物技術信息中心(NCBI)遺傳序列數(shù)據(jù)庫中，均有相應的GenBank號。具體見下表表肺血栓栓塞癥相關基因


為實現(xiàn)本發(fā)明另一個發(fā)明目的，將上述與肺血栓栓塞癥相關142個基因，合成的對應的寡核苷酸探針，通過接觸式點樣的方式，將探針固定在片基上，制備基因芯片及相關制備檢測試劑，組成檢測試劑盒，可應用于肺血栓栓塞癥的早期檢測和診斷。本發(fā)明具有良好的發(fā)展前景。
基因序列表<110>同濟人學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>1<211>2876<212>DNA<213>人類(Homo sapiens)<400>11 gaattcctgc agctcagcag ccgccgccag agcaggacga accgccaatc gcaaggcacc61 tctgagaact tcaggatgca gatgtctcca gccctcacct gcctagtcct gggcctggcc121 cttgtctttg gtgaagggtc tgctgtgcac catcccccat cctacgtggc ccacctggcc181 tcagacttcg gggtgagggt gtttcagcag gtggcgcagg cctccaagga ccgcaacgtg241 gttttctcac cctatggggt ggcctcggtg ttggccatgc tccagctgac aacaggagga301 gaaacccagc agcagattca agcagctatg ggattcaaga ttgatgacaa gggcatggcc361 cccgccctcc ggcatctgta caaggagctc atggggccat ggaacaagga tgagatcagc421 accacagacg cgatcttcgt ccagcgggat ctgaagctgg tccagggctt catgccccac481 ttcttcaggc tgttccggag cacggtcaag caagtggact tttcagaggt ggagagagcc541 agattcatca tcaatgactg ggtgaagaca cacacaaaag gtatgatcag caacttgctt601 gggaaaggag ccgtggacca gctgacacgg ctggtgctgg tgaatgccct ctacttcaac661 ggccagtgga agactccctt ccccgactcc agcacccacc gccgcctctt ccacaaatca721 gacggcagca ctgtctctgt gcccatgatg gctcagacca acaagttcaa ctatactgag781 ttcaccacgc ccgatggcca ttactacgac atcctggaac tgccctacca cggggacacc841 ctcagcatgt tcattgctgc cccttatgaa aaagaggtgc ctctctctgc cctcaccaac901 attctgagtg cccagctcat cagccactgg aaaggcaaca tgaccaggct gccccgcctc961 ctggttctgc ccaagttctc cctggagact gaagtcgacc tcaggaagcc cctagagaac1021 ctgggaatga ccgacatgtt cagacagttt caggctgact tcacgagtct ttcagaccaa1081 gagcctctcc acgtcgcgca ggcgctgcag aaagtgaaga tcgaggtgaa cgagagtggc1141 acggtggcct cctcatccac agctgtcata gtctcagccc gcatggcccc cgaggagatc1201 atcatggaca gacccttcct ctttgtggtc cggcacaacc ccacaggaac agtccttttc1261 atgggccaag tgatggaacc ctgaccctgg ggaaagacgc cttcatctgg gacaaaactg1321 gagatgcatc gggaaagaag aaactccgaa gaaaagaatt ttagtgttaa tgactctttc1381 tgaaggaaga gaagacattt gccttttgtt aaaagatggt aaaccagatc tgtctccaag1441 accttggcct ctccttggag gacctttagg tcaaactccc tagtctccac ctgagaccct1501 gggagagaag tttgaagcac aactccctta aggtctccaa accagacggt gacgcctgcg1561 ggaccatctg gggcacctgc ttccacccgt ctctctgccc actcgggtct gcagacctgg1621 ttcccactga ggccctttgc aggatggaac tacggggctt acaggagctt ttgtgtgcct1681 ggtagaaact atttctgttc cagtcacatt gccatcactc ttgtactgcc tgccaccgcg1741 gaggaggctg gtgacaggcc aaaggccagt ggaagaaaca ccctttcatc tcagagtcca1801 ctgtggcact ggccacccct ccccagtaca ggggtgctgc aggtggcaga gtgaatgtcc1861 cccatcatgt ggcccaactc tcctggcctg gccatctccc tccccagaaa cagtgtgcat1921 gggttatttt ggagtgtagg tgacttgttt actcattgaa gcagatttct gcttcctttt1981 atttttatag gaatagagga agaaatgtca gatgcgtgcc cagctcttca ccccccaatc2041 tcttggtggg gaggggtgta cctaaatatt tatcatatcc ttgcccttga gtgcttgtta2101 gagagaaaga gaactactaa ggaaaataat attatttaaa ctcgctccta gtgtttcttt2161 gtggtctgtg tcaccgtatc tcaggaagtc cagccacttg actggcacac acccctccgg
2221 acatccagcg tgacggagcc cacactgcca ccttgtggcc gcctgagaccctcgcgcccc2281 ccgcgccccc cgcgcccctc tttttcccct tgatggaaat tgaccataca atttcatcct2341 ccttcagggg atcaaaagga cggagtgggg ggacagagac tcagatgagg acagagtggt2401 ttccaatgtg ttcaatagat ttaggagcag aaatgcaagg ggctgcatga cctaccagga2461 cagaactttc cccaattaca gggtgactca cagccgcatt ggtgactcac ttcaatgtgt2521 catttccggc tgctgtgtgt gagcagtgga cacgtgaggg gggggtgggt gagagagaca2581 ggcagctcgg attcaactac cttagataat atttctgaaa acctaccagc cagagggtag2641 ggcacaaaga tggatgtaat gcactttggg aggccaaggc gggaggattg cttgagccca2701 ggagttcaag accagcctgg gcaacatacc aagacccccg tctctttaaa aatatatata2761 ttttaaatat acttaaatat atatttctaa tatctttaaa tatatatata tattttaaag2821 accaatttat gggagaattg cacacagatg tgaaatgaat gtaatctaat agaagc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>2<211>1853<212>DNA<213>人類(Homo sapiens)<400>21 gagggtctgt ggtcctctga tcaacatagg ctggtgggag tacaggactc gcctcctcag61 ggttccctgt gctgccactt ttcagccatg gccacaagtg aacagagtat ctgccaagcc121 cgggcttccg tgatggtcta cgatgacacc agtaagaaat gggtaccaat caaacctggc181 cagcagggat tcagccggat caacatctac cacaacactg ccagcaacac cttcagagtc241 gttggagtca agttgcagga tcagcaggtt gtgatcaatt attcaatcgt gaaagggctg301 aagtacaatc aggccacgcc aaccttccac cagtggcgag atgcccgcca ggtctacggc361 ttaaactttg caagtaaaga agaggcaacc acgttctcca atgcaatgct gtttgccctg421 aacatcatga attcccaaga aggaggcccc tccagccagc gtcaggtgca gaatggcccc481 tctcctgatg agatggacat ccagagaaga caagtgatgg agcagcacca gcagcagcgt541 caggaatctc tagaaagaag aacctcggcc acagggccca tcctcccacc aggacatcct601 tcatctgcag ccagcgcccc cgtctcatgt agtgggcctc caccgccccc cccaccccca661 gtcccacctc cacccactgg ggctacccca cctcccccac ccccactgcc agccggagga721 gcccaggggt ccagccacga cgagagctcc atgtcaggac tggccgctgc catagctggg781 gccaagctga gaagagtcca acggccagaa gacgcatctg gaggctccag tcccagtggg841 acctcaaagt ccgatgccaa ccgggcaagc agcgggggtg gcggaggagg cctcatggag901 gaaatgaaca aactgctggc caagaggaga aaagcagcct cccagtcaga caagccagcc961 gagaagaagg aagatgaaag ccaaatggaa gatcctagta cctccccctc tccggggacc1021 cgagcagcca gccagccacc taactcctca gaggctggcc ggaagccctg ggagcggagc1081 aactcggtgg agaagcctgt gtcctcgatt ctgtccagaa ccccgtctgt ggcaaagagc1141 cccgaagcta agagccccct tcagtcgcag cctcactcta ggatgaagcc tgctgggagc1201 gtgaatgaca tggccctgga tgccttcgac ttggaccgga tgaagcagga gatcctagag1261 gaggtggtga gagagctcca caaggtgaag gaggagatca tcgacgccat caggcaggag1321 ctgagtggga tcagcaccac gtaaggggcc ggcctcgctg cgctgattcg tcgagcccat1381 ccggcgacag aggacagcca gaagcccagc cagccccaga ctccagtgca ccagagcacg1441 cacaggagcc tgggcgcgct gctgtgaaac gtcctgacct gtgatcacac atgacagtga1501 ggaaaccaag tgcaactcct gggttttttt agattctgcc tgacacggaa caccaggtct1561 gctcgtcttt tttgtgtttt atatttgctt atttaaggta catttctttg ggtttctaga1621 gacgccccta agtcacctgc ttcattagac ggtttccagg ttttctccca ggtgacgctg
1681 ttagcgcctc agctggcggt gacagccggc ccagcgtggc gccaccacac accgcagagc1741 tgtccaggca cagctccgtc cccagcgctc atggtgttga aactgtctgt catgcaccac1801 ggtgtctgtg tccacacagt aataaacggt ttactgtccg caaaaaaaaa aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>3<211>3236<212>DNA<213>人類(Homo sapiens)<400>31 gtgacccacc tgcctcctcc gcagagcaat ggcggtgtct gccgggtccg cgcggacctc61 gcccagctca gataaagtac agaaagacaa ggctgaactg atctcagggc ccaggcagga121 cagccgaata gggaaactct tgggttttga gtggacagat ttgtccagtt ggcggaggct181 ggtgaccctg ctgaatcgac caacggaccc tgcaagctta gctgtctttc gttttctttt241 tgggttcttg atggtgctag acattcccca ggagcggggg ctcagctctc tggaccggaa301 ataccttgat gggctggatg tgtgccgctt ccccttgctg gatgccctac gcccactgcc361 acttgactgg atgtatcttg tctacaccat catgtttctg ggggcactgg gcatgatgct421 gggcctgtgc taccggataa gctgtgtgtt attcctgctg ccatactggt atgtgtttct481 cctggacaag acatcatgga acaaccactc ctatctgtat gggttgttgg cctttcagct541 aacattcatg gatgcaaacc actactggtc tgtggacggt ctgctgaatg cccataggag601 gaatgcccac gtgccccttt ggaactatgc agtgctccgt ggccagatct tcattgtgta661 cttcattgcg ggtgtgaaaa agctggatgc agactgggtt gaaggctatt ccatggaata721 tttgtcccgg cactggctct tcagtccctt caaactgctg ttgtctgagg agctgactag781 cctgctggtc gtgcactggg gtgggctgct gcttgacctc tcagctggtt tcctgctctt841 ttttgatgtc tcaagatcca ttggcctgtt ctttgtgtcc tacttccact gcatgaattc901 ccagcttttc agcattggta tgttctccta cgtcatgctg gccagcagcc ctctcttctg961 ctcccctgag tggcctcgga agctggtgtc ctactgcccc cgaaggttgc aacaactgtt1021 gcccctcaag gcagcccctc agcccagtgt ttcctgtgtg tataagagga gccggggcaa1081 aagtggccag aagccagggc tgcgccatca gctgggagct gccttcaccc tgctctacct1141 cctggagcag ctattcctgc cctattctca ttttctcacc cagggctata acaactggac1201 aaatgggctg tatggctatt cctgggacat gatggtgcac tcccgctccc accagcacgt1261 gaagatcacc taccgtgatg gccgcactgg cgaactgggc taccttaagc ctggggtatt1321 tacacagagt cggcgatgga aggatcatgc agacatgctg aagcaatatg ccacttgcct1381 gagccgcctg cttcccaagt ataatgtcac tgagccccag atctactttg atatttgggt1441 ctccatcaat gaccgcttcc agcagaggat ttttgaccct cgtgtggaca tcgtgcaggc1501 cgcttggtca ccctttcagc gcacatcctg ggtgcaacca ctcttgatgg acctgtctcc1561 ctggagggcc aagttacagg aaatcaagag cagcctagac aaccacactg aggtggtctt1621 cattgcagat ttccctggac tgcacttgga gaattttgtg agtgaagacc tgggcaacac1681 tagcatccag ctgctgcagg gggaagtgac tgtggagctt gtggcagaac agaagaacca1741 gactcttcga gagggagaaa aaatgcagtt gcctgctggt gagtaccata aggtgtatac1801 gacatcacct agcccttctt gctacatgta cgtctatgtc aacactacag agcttgcact1861 ggagcaagac ctggcatatc tgcaagaatt aaaggaaaag gtggagaatg gaagtgaaac1921 agggcctcta cccccagagc tgcagcctct gttggaaggg gaagtaaaag ggggccctga1981 gccaacacct ctggttcaga cctttcttag acgccaagaa aggctccagg agattgaacg2041 ccggcgaaat actcctttcc atgagcgatt cttccgcttc ttgttgcgaa agctctatgt2101 ctttcgccgc agcttcctga tgacttgtat ctcacttcga aatctgatat taggccgtcc2161 ttccctggag cagctggccc aggaggtgac ttatgcaaac ttgagaccct ttgaggcagt
2221 tggagaactg aatccctcaa acacggattc ttcacattct aatcctcctg agtcaaatcc2281 tgatcctgtc cactcagagt tctgaagggg gccagatgtt gggtgcagat gtagaagcag2341 ccagtcacag acccattcta tgcaatggac atttatttga aaaaaattct caaaagtttt2401 tttttttttt ttgggggggc ggggttctaa agctgttttt aactccgaga ttacaactta2461 gaggaaccaa ggaaataaag caaataagat ttaacaaccc aagattaaga ggccaggaag2521 aggttagacg caatgtgaaa ctgtcctcct aggataaggt ttaaagtggc tttttggggg2581 ctgggtgccg tggctcacgc ctgtaatccc agcattttgg gaggctgagg tgggcagatc2641 acttgaggcc aggagttcga gaccagcctg gccaacatgg caaaacccct tctctactaa2701 aaatacaaaa attagccaga cgtggtggtg ggtgcctgta atccaactac ccaggaggct2761 gaggcatgag aatcgcttgg gcccaggagg tggaggttgc agtgagccga gatcgagcca2821 ctgcactcct gggcaacaga gcaagacttc gtctcaaaat aaataaataa agtggctctt2881 ggggaaaagc aatttaatgt accacgatga atagctaact gttcccaagt gtttgctatg2941 tgcaacacac cgcgtgagca gtgttacctg cattattaca ttaggctgag aggtaaaata3001 atttgcccga agacatacag ctagtgacga atggactgat ggtttgaact taacgtctat3061 ttgacttaag gtcctgcacc ctgccacttg taattttcag aatcactgat aatctgaaat3121 aatgcagctt aaaacatgtt ttcttaatta aaagtataaa aaaaaaaaaa aaaaaaaaaa3181 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>4<211>2446<212>DNA<213>人類(Homo sapiens)<400>41 ggctgccagc gtttcatgat caacatggga gactcccacg tggacaccag ctccaccgtg61 tccgaggcgg tggccgaaga agtatctctt ttcagcatga cggacatgat tctgttttcg121 ctcatcgtgg gtctcctaac ctactggttc ctcttcagaa agaaaaaaga agaagtcccc181 gagttcacca aaattcagac attgacctcc tctgtcagag agagcagctt tgtggaaaag241 atgaagaaaa cggggaggaa catcatcgtg ttctagggct cccagacggg gactgcagag301 gagtttgcca accgcctgtc caaggacgcc caccgctacg ggatgcgagg catgtcagcg361 gaccctgagg agtatgacct ggccgacctg agcagcctgc cagagatcga caacgccctg421 gtggttttct gcatggccac ctacggtgag ggagacccca ccgacaatgc ccaggacttc481 tacgactggc tgcaggagac agacgtggat ctctctgggg tcaagttcgc ggtgtttggt541 cttgggaaca agacctacga gcacttcaat gccatgggca agtacgtgga caagcggctg601 gagcagctcg gcgcccagcg catctttgag ctggggttgg gcgacgacga tgggaacttg661 gaggaggact tcatcacctg gcgagagcag ttctggctgg ccgtgtgtga acactttggg721 gtggaagcca ctggcgagga gtccagcatt cgccagtacg agcttgtggt ccacaccgac781 atagatgcgg ccaaggtgta catgggggag atgggccggc tgaagagcta cgagaaccag841 aagcccccct ttgatgccaa gaatccgttc ctggctgcag tcaccaccaa ccggaagctg901 aaccagggaa ccgagcgcca cctcatgcac ctggaattgg acatctcgga ctccaaaatc961 aggtatgaat ctggggacca cgtggctgtg tacccagcca acgactctgc tctcgtcaac1021 cagctgggca aaatcctggg tgccgacctg gacgtcgtca tgtccctgaa caacctggat1081 gaggagtcca acaagaagca cccattcccg tgccctacgt cctaccgcac ggccctcacc1141 tactacctgg acatcaccaa cccgccgcgt accaacgtgc tgtacgagct ggcgcagtac1201 gcctcggagc cctcggagca ggagctgctg cgcaagatgg cctcctcctc cggcgagggc1261 aaggagctgt acctgagctg ggtggtggag gcccggaggc acatcctggc catcctgcag
1321 gactgcccgt ccctgcggcc ccccatcgac cacctgtgtg agctgctgcc gcgcctgcag1381 gcccgctact actccatcgc ctcatcctcc aaggtccacc ccaactctgt gcacatctgt1441 gcggtggttg tggagtacga gaccaaggcc ggccgcatca acaagggcgt ggccaccaac1501 tggctgcggg ccaaggagcc tgtcggggag aacggcggcc gtgcgctggt gcccatgttc1561 gtgcgcaagt cccagttccg cctgcccttc aaggccacca cgcctgtcat catggtgggc1621 cccggcaccg gggtggcacc cttcataggc ttcatccagg agcgggcctg gctgcgacag1681 cagggcaagg aggtggggga gacgctgctg tactacggct gccgccgctc ggatgaggac1741 tacctgtacc gggaggagct ggcgcagttc cacagggacg gtgcgctcac ccagctcaac1801 gtggccttct cccgggagca gtcccacaag gtctacgtcc agcacctgct aaagcaagac1861 cgagagcagc tgtggaagtt gatcgaaggc ggtgcccaca tctacgtctg tggggatgca1921 cggaacatgg ccagggatgt gcagaacacc ttctacgaca tcgtggctga gctcggggcc1981 atggagcacg cgcaggcggt ggactacatc aagaaactga tgaccaaggg ccgctactcc2041 ctggacgtgt ggagctaggg gcctgcctgc cccacccacc ccacagactc cggcctgtaa2101 tcagctctcc tggctccctc ccgtagtctc ctgggtgtgt ttggcttggc cttggcatgg2161 gcgcaggccc agtgacaaag actcctctgg gcctggggtg catcctcctc agcccccagg2221 ccaggtgagg tccaccggcc cctggcagca cagcccaggg cctgcatggg ggcaccgggc2281 tccatgcctc tggaggcctc tggccctcgg tggctgcaca gaagggctct ttctctctgc2341 tgagctgggc ccagcccctc cacatgattt ccagtgagtg taaataattt taaataacct2401 ctggcccttg gaataaagtt ctgttttctg taaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>5<211>1056<212>DNA<213>人類(Homo sapiens)<400>51 gtctgcgcgg agtctgagcg gcgctcgtcc cgtcccaagg ccgacgccag cacgccgtca61 tggcccccgc agcggcgacg gggggcagca ccctgcccag tggcttctcg gtcttcacca121 ccttgcccga cttgctcttc atctttgagt ttatcttcgg gggcctggtg tggatcctgg181 tggcctcctc cctggtgccc tggcccctgg tccagggctg ggtgatgttc gtgtctgtgt241 tctgcttcgt ggccaccacc accttgatca tcctgtacat aattggagcc cacggtggag301 agacttcctg ggtcaccttg gacgcagcct accactgcac cgctgccctc ttttacctca361 gcgcctcagt cctggaggcc ctggccacca tcacgatgca agacggcttc acctacaggc421 actaccatga aaacattgct gccgtggtgt tctcctacat agccactctg ctctacgtgg481 tccatgcggt gttctcttta atcagatgga agtcttcata aagccgcagt agaacttgag541 ctgaaaaccc agatggtgtt aactggccgc cccactttcc ggcataactt tttagaaaac601 agaaatgccc ttgatggtgg aaaaaagaaa acaaccaccc ccccactgcc caaaaaaaaa661 agccctgccc tgttgctcgt gggtgctgtg tttactctcc cgtgtgcctt cgcgtccggg721 ttgggagctt gctgtgtcta acctccaact gctgtgctgt ctgctagggt cacctcctgt781 ttgtgaaagg ggaccttctt gttcgggggt gggaagtggc gaccgtgacc tgagaaggaa841 agaaagatcc tctgctgacc cctggagcag ctctcgagaa ctacctgttg gtattgtcca901 caagctctcc cgagcgcccc atcttgtgcc atgttttaag tcttcatgga tgttctgcat961 gtcatgggga ctaaaactca cccaacagat ctttccagag gtccatggtg gaagacgata1021 accctgtgaa atactttata aaatgtctta atgttc<110>同濟大學附屬同濟醫(yī)院
<120>肺血栓栓塞癥相關基因及其應用<160>142<210>6<211>8923<212>DNA<213>人類(Homo sapiens)<400>61 agctcacagc tattgtggtg ggaaagggag ggtggttggt ggatgtcaca gcttgggctt61 tatctccccc agcagtgggg actccacagc ccctgggcta cataacagca agacagtccg121 gagctgtagc agacctgatt gagcctttgc agcagctgag agcatggcct agggtgggcg181 gcaccattgt ccagcagctg agtttcccag ggaccttgga gatagccgca gccctcattt241 gcaggggaag gcaccattgt ccagcagctg agtttcccag ggaccttgga gatagccgca301 gccctcattt atgattcctg ccagatttgc cggggtgctg cttgctctgg ccctcatttt361 gccagggacc ctttgtgcag aaggaactcg cggcaggtca tccaccggccc gatgcagcct421 tttcggaagt gacttcgtca acacctttga tgggagcatg tacagctttg cgggatactg481 cagttacctc ctggcagggg gctgccagaa acgctccttc tcgattattg gggacttcca541 gaatggcaag agagtgagcc tctccgtgta tcttggggaa ttttttgaca tccatttgtt601 tgtcaatggt accgtgacac agggggacca aagagtctcc atgccctatg cctccaaagg661 gctgtatcta gaaactgagg ctgggtacta caagctgtcc ggtgaggcct atggctttgt721 ggccaggatc gatggcagcg gcaactttca agtcctgctg tcagacagat acttcaacaa781 gacctgcggg ctgtgtggca actttaacat ctttgctgaa gatgacttta tgacccaaga841 agggaccttg acctcggacc cttatgactt tgccaactca tgggctctga gcagtggaga901 acagtggtgt gaacgggcat ctcctcccag cagctcatgc aacatctcct ctggggaaat961 gcagaagggc ctgtgggagc agtgccagct tctgaagagc acctcggtgt ttgcccgctg1021 ccaccctctg gtggaccccg agccttttgt ggccctgtgt gagaagactt tgtgtgagtg1081 tgctgggggg ctggagtgcg cctgccctgc cctcctggag tacgcccgga cctgtgccca1141 ggagggaatg gtgctgtacg gctggaccga ccacagcgcg tgcagcccag tgtgccctgc1201 tggtatggag tataggcagt gtgtgtcccc ttgcgccagg acctgccaga gcctgcacat1261 caatgaaatg tgtcaggagc gatgcgtgga tggctgcagc tgccctgagg gacagctcct1321 ggatgaaggc ctctgcgtgg agagcaccga gtgtccctgc gtgcattccg gaaagcgcta1381 ccctcccggc acctccctct ctcgagactg caacacctgc atttgccgaa acagccagtg1441 gatctgcagc aatgaagaat gtccagggga gtgccttgtc actggtcaat cccacttcaa1501 gagctttgac aacagatact tcaccttcag tgggatctgc cagtacctgc tggcccggga1561 ttgccaggac cactccttct ccattgtcat tgagactgtc cagtgtgctg atgaccgcga1621 cgctgtgtgc acccgctccg tcaccgtccg gctgcctggc ctgcacaaca gccttgtgaa1681 actgaagcat ggggcaggag ttgccatgga tggccaggac atccagctcc ccctcctgaa1741 aggtgacctc cgcatccagc atacagtgac ggcctccgtg cgcctcagct acggggagga1801 cctgcagatg gactgggatg gccgcgggag gctgctggtg aagctgtccc ccgtctacgc1861 cgggaagacc tgcggcctgt gtgggaatta caatggcaac cagggcgacg acttccttac1921 cccctctggg ctggcagagc cccgggtgga ggacttcggg aacgcctgga agctgcacgg1981 ggactgccag gacctgcaga agcagcacag cgatccctgc gccctcaacc cgcgcatgac2041 caggttctcc gaggaggcgt gcgcggtcct gacgtccccc acattcgagg cctgccatcg2101 tgccgtcagc ccgctgccct acctgcggaa ctgccgctac gacgtgtgct cctgctcgga2161 cggccgcgag tgcctgtgcg gcgccctggc cagctatgcc gcggcctgcg cggggagagg2221 cgtgcgcgtc gcgtggcgcg agccaggccg ctgtgagctg aactgcccga aaggccaggt2281 gtacctgcag tgcgggaccc cctgcaacct gacctgccgc tctctctctt acccggatga2341 ggaatgcaat gaggcctgcc tggagggctg cttctgcccc ccagggctct acatggatga2401 gaggggggac tgcgtgccca aggcccagtg cccctgttac tatgacggtg agatcttcca
2461 gccagaagac atcttctcag accatcacac catgtgctac tgtgaggatg gcttcatgca2521 ctgtaccatg agtggagtcc ccggaagctt gctgcctgac gctgtcctca gcagtcccct2581 gtctcatcgc agcaaaagga gcctatcctg tcggcccccc atggtcaagc tggtgtgtcc2641 cgctgacaac ctgcgggctg aagggctcga gtgtaccaaa acgtgccaga actatgacct2701 ggagtgcatg agcatgggct gtgtctctgg ctgcctctgc cccccgggca tggtccggca2761 tgagaacaga tgtgtggccc tggaaaggtg tccctgcttc catcagggca aggagtatgc2821 ccctggagaa acagtgaaga ttggctgcaa cacttgtgtc tgtcgggacc ggaagtggaa2881 ctgcacagac catgtgtgtg atgccacgtg ctccacgatc ggcatggccc actacctcac2941 cttcgacggg ctcaaatacc tgttccccgg ggagtgccag tacgttctgg tgcaggatta3001 ctgcggcagt aaccctggga cctttcggat cctagtgggg aataagggat gcagccaccc3061 ctcagtgaaa tgcaagaaac gggtcaccat cctggtggag ggaggagaga ttgagctgtt3121 tgacggggag gtgaatgtga agaggcccat gaaggatgag actcactttg aggtggtgga3181 gtctggccgg tacatcattc tgctgctggg caaagccctc tccgtggtct gggaccgcca3241 cctgagcatc tccgtggtcc tgaagcagac ataccaggag aaagtgtgtg gcctgtgtgg3301 gaattttgat ggcatccaga acaatgacct caccagcagc aacctccaag tggaggaaga3361 ccctgtggac tttgggaact cctggaaagt gagctcgcag tgtgctgaca ccagaaaagt3421 gcctctggac tcatcccctg ccacctgcca taacaacatc atgaagcaga cgatggtgga3481 ttcctcctgt agaatcctta ccagtgacgt cttccaggac tgcaacaagc tggtggaccc3541 cgagccatat ctggatgtct gcatttacga cacctgctcc tgtgagtcca ttggggactg3601 cgcctgcttc tgcgacacca ttgctgccta tgcccacgtg tgtgcccagc atggcaaggt3661 ggtgacctgg aggacggcca cattgtgccc ccagagctgc gaggagagga atctccggga3721 gaacgggtat gagtgtgagt ggcgctataa cagctgtgca cctgcctgtc aagtcacgtg3781 tcagcaccct gagccactgg cctgccctgt gcagtgtgtg gagggctgcc atgcccactg3841 ccctccaggg aaaatcctgg atgagctttt gcagacctgc gttgaccctg aagactgtcc3901 agtgtgtgag gtggctggcc ggcgttttgc ctcaggaaag aaagtcacct tgaatcccag3961 tgaccctgag cactgccaga tttgccactg tgatgttgtc aacctcacct gtgaagcctg4021 ccaggagccg ggaggcctgg tggtgcctcc cacagatgcc ccggtgagcc ccaccactct4081 gtatgtggag gacatctcgg aaccgccgtt gcacgatttc tactgcagca ggctactgga4141 cctggtcttc ctgctggatg gctcctccag gctgtccgag gctgagtttg aagtgctgaa4201 ggcctttgtg gtggacatga tggagcggct gcgcatctcc cagaagtggg tccgcgtggc4261 cgtggtggag taccacgacg gctcccacgc ctacatcggg ctcaaggacc ggaagcgacc4321 gtcagagctg cggcgcattg ccagccaggt gaagtatgcg ggcagccagg tggcctccac4381 cagcgaggtc ttgaaataca cactgttcca aatcttcagc aagatcgacc gccctgaagc4441 ctcccgcatc gccctgctcc tgatggccag ccaggagccc caacggatgt cccggaactt4501 tgtccgctac gtccagggcc tgaagaagaa gaaggtcatt gtgatcccgg tgggcattgg4561 gccccatgcc aacctcaagc agatccgcct catcgagaag caggcccctg agaacaaggc4621 cttcgtgctg agcagtgtgg atgagctgga gcagcaaagg gacgagatcg ttagctacct4681 ctgtgacctt gcccctgaag cccctcctcc tactctgccc ccccacatgg cacaagtcac4741 tgtgggcccg gggctcttgg gggtttcgac cctggggccc aagaggaact ccatggttct4801 ggatgtggcg ttcgtcctgg aaggatcgga caaaattggt gaagccgact tcaacaggag4861 caaggagttc atggaggagg tgattcagcg gatggatgtg ggccaggaca gcatccacgt4921 cacggtgctg cagtactcct acatggtgac cgtggagtac cccttcagcg aggcacagtc4981 caaaggggac atcctgcagc gggtgcgaga gatccgctac cagggcggca acaggaccaa5041 cactgggctg gccctgcggt acctctctga ccacagcttc ttggtcagcc agggtgaccg5101 ggagcaggcg cccaacctgg tctacatggt caccggaaat cctgcctctg atgagatcaa5161 gaggctgcct ggagacatcc aggtggtgcc cattggagtg ggccctaatg ccaacgtgca5221 ggagctggag aggattggct ggcccaatgc ccctatcctc atccaggact ttgagacgct5281 cccccgagag gctcctgacc tggtgctgca gaggtgctgc tccggagagg ggctgcagat
5341 ccccaccctc tcccctgcac ctgactgcag ccagcccctg gacgtgatcc ttctcctgga5401 tggctcctcc agtttcccag cttcttattt tgatgaaatg aagagtttcg ccaaggcttt5461 catttcaaaa gccaatatag ggcctcgtct cactcaggtg tcagtgctgc agtatggaag5521 catcaccacc attgacgtgc catggaacgt ggtcccggag aaagcccatt tgctgagcct5581 tgtggacgtc atgcagcggg agggaggccc cagccaaatc ggggatgcct tgggctttgc5641 tgtgcgatac ttgacttcag aaatgcatgg tgccaggccg ggagcctcaa aggcggtggt5701 catcctggtc acggacgtct ctgtggattc agtggatgca gcagctgatg ccgccaggtc5761 caacagagtg acagtgttcc ctattggaat tggagatcgc tacgatgcag cccagctacg5821 gatcttggca ggcccagcag gcgactccaa cgtggtgaag ctccagcgaa tcgaagacct5881 ccctaccatg gtcaccttgg gcaattcctt cctccacaaa ctgtgctctg gatttgttag5941 gatttgcatg gatgaggatg ggaatgagaa gaggcccggg gacgtctgga ccttgccaga6001 ccagtgccac accgtgactt gccagccaga tggccagacc ttgctgaaga gtcatcgggt6061 caactgtgac cgggggctga ggccttcgtg ccctaacagc cagtcccctg ttaaagtgga6121 agagacctgt ggctgccgct ggacctgccc ctgcgtgtgc acaggcagct ccactcggca6181 catcgtgacc tttgatgggc agaatttcaa gctgactggc agctgttctt atgtcctatt6241 tcaaaacaag gagcaggacc tggaggtgat tctccataat ggtgcctgca gccctggagc6301 aaggcagggc tgcatgaaat ccatcgaggt gaagcacagt gccctctccg tcgagctgca6361 cagtgacatg gaggtgacgg tgaatgggag actggtctct gttccttacg tgggtgggaa6421 catggaagtc aacgtttatg gtgccatcat gcatgaggtc agattcaatc accttggtca6481 catcttcaca ttcactccac aaaacaatga gttccaactg cagctcagcc ccaagacttt6541 tgcttcaaag acgtatggtc tgtgtgggat ctgtgatgag aacggagcca atgacttcat6601 gctgagggat ggcacagtca ccacagactg gaaaacactt gttcaggaat ggactgtgca6661 gcggccaggg cagacgtgcc agcccatcct ggaggagcag tgtcttgtcc ccgacagctc6721 ccactgccag gtcctcctct taccactgtt tgctgaatgc cacaaggtcc tggctccagc6781 cacattctat gccatctgcc agcaggacag ttgccaccag gagcaagtgt gtgaggtgat6841 cgcctcttat gcccacctct gtcggaccaa cggggtctgc gttgactgga ggacacctga6901 tttctgtgct atgtcatgcc caccatctct ggtctacaac cactgtgagc atggctgtcc6961 ccggcactgt gatggcaacg tgagctcctg tggggaccat ccctccgaag gctgtttctg7021 ccctccagat aaagtcatgt tggaaggcag ctgtgtccct gaagaggcct gcactcagtg7081 cattggtgag gatggagtcc agcaccagtt cctggaagcc tgggtcccgg accaccagcc7141 ctgtcagatc tgcacatgcc tcagcgggcg gaaggtcaac tgcacaacgc agccctgccc7201 cacggccaaa gctcccacgt gtggcctgtg tgaagtagcc cgcctccgcc agaatgcaga7261 ccagtgctgc cccgagtatg agtgtgtgtg tgacccagtg agctgtgacc tgcccccagt7321 gcctcactgt gaacgtggcc tccagcccac actgaccaac cctggcgagt gcagacccaa7381 cttcacctgc gcctgcagga aggaggagtg caaaagagtg tccccaccct cctgcccccc7441 gcaccgtttg cccacccttc ggaagaccca gtgctgtgat gagtatgagt gtgcctgcaa7501 ctgtgtcaac tccacagtga gctgtcccct tgggtacttg gcctcaaccg ccaccaatga7561 ctgtggctgt accacaacca cctgccttcc cgacaaggtg tgtgtccacc gaagcaccat7621 ctaccctgtg ggccagttct gggaggaggg ctgcgatgtg tgcacctgca ccgacatgga7681 ggatgccgtg atgggcctcc gcgtggccca gtgctcccag aagccctgtg aggacagctg7741 tcggtcgggc ttcacttacg ttctgcatga aggcgagtgc tgtggaaggt gcctgccatc7801 tgcctgtgag gtggtgactg gctcaccgcg gggggactcc cagtcttcct ggaagagtgt7861 cggctcccag tgggcctccc cggagaaccc ctgcctcatc aatgagtgtg tccgagtgaa7921 ggaggaggtc tttatacaac aaaggaacgt ctcctgcccc cagctggagg tccctgtctg7981 cccctcgggc tttcagctga gctgtaagac ctcagcgtgc tgcccaagct gtcgctgtga8041 gcgcatggag gcctgcatgc tcaatggcac tgtcattggg cccgggaaga ctgtgatgat8101 cgatgtgtgc acgacctgcc gctgcatggt gcaggtgggg gtcatctctg gattcaagct8161 ggagtgcagg aagaccacct gcaacccctg ccccctgggt tacaaggaag aaaataacac
8221 aggtgaatgt tgtgggagat gtttgcctac ggcttgcacc attcagctaa gaggaggaca8281 gatcatgaca ctgaagcgtg atgagacgct ccaggatggc tgtgatactc acttctgcaa8341 ggtcaatgag agaggagagt acttctggga gaagagggtc acaggctgcc caccctttga8401 tgaacacaag tgtctggctg agggaggtaa aattatgaaa attccaggca cctgctgtga8461 cacatgtgag gagcctgagt gcaacgacat cactgccagg ctgcagtatg tcaaggtggg8521 aagctgtaag tctgaagtag aggtggatat ccactactgc cagggcaaat gtgccagcaa8581 agccatgtac tccattgaca tcaacgatgt gcaggaccag tgctcctgct gctctccgac8641 acggacggag cccatgcagg tggccctgca ctgcaccaat ggctctgttg tgtaccatga8701 ggttctcaat gccatggagt gcaaatgctc ccccaggaag tgcagcaagt gaggctgctg8761 cagctgcatg ggtgcctgct gctgcctgcc ttggcctgat ggccaggcca gagtgctgcc8821 agtcctctgc atgttctgct cttgtgccct tctgagccca caataaaggc tgagctctta8881 tcttgctgca tgttctgctc ttgtgccctt ctgagcccac aat<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>7<211>2826<212>DNA<213>人類(Homo sapiens)<400>71 gctccaagaa accagccaac ggctggagga tgtggaggag caggtagggt ggctcatggc61 tacattagat tcaggggaca tctcctcaga tgccctgcaa accatgaaat aaaaatggag121 gaggaacaac aacaacaaac aaaaaaaaaa agcaaagagg aactgcaagt tcagtcccta181 gcgactaaca gtgagcagag gaagtaaagg gggagttgta agagaggcgg tatcaacagc241 ctgctgatga aagaggcgac tctgcagaaa gaggcaactt gacatatcag gactttaacc301 gctgtagaaa tagctcaggc ataccaagcc catgcaaaca cagaattgca gaagttcagg361 agaggcttat cacttccctg agaagaaaaa cacattttca gttttgcctg catcataaga421 gtgagcactc cattgctttc tttcctggcc acactgctac aatccagcac taactatcca481 tgtccagggt aaggatcgag atcgagaagc ccacactgcc agtgaaaaag ctacgtcttt541 actgcataaa ttagaggaag caatttcgga acaacggaac cttcaaacta taaatactga601 attatcgaac acttgccagg cacttcagca gaagacaagg aaactgaaga agctttttag661 atgaggaatt tcctcactat gattccctgt cctgcgcaga tgcaattcaa caacctcttc721 aagaaaaatt gaagcagtgt tgccacaaac tatatggtgg tcaagaagca agaatacatc781 agacacccct gaccttgaaa catacgtgct ggtacacacc tctgctggat gccttatctc841 tggatagttt tacagcagtt ccaaccctgg aatcaacacc tttctcaggt gtagccaacc901 aaatccacac tctgtgtgaa aggcccacat atggagaagt aaaggatggt gctttggatg961 taaaaagaca acacaagtgc ccaggcccca caagtggccc cagcccagga acgaatctct1021 caggctgcat caggatgaat gatgacccaa gtatggaaga gaatggtgtt gaacgcgtgt1081 gtcctgagag cctgctgcag tccagggaat attcctcact accattaccc agacacactt1141 catcgacaga cggtactata acttcaagtg atcctggatt agaaattctg aatatggctt1201 cttgtgacct tgacagaaac tcgctctgta agaaagagga ggatacaaga tcagcttctc1261 ccacgataga ggcccaaggc acaagtccag ctcatgataa tattgcattc caagactcta1321 cgagtaagga taaaaccata ttaaatctgg aagccaaaga ggaaccagaa acaatagaag1381 aacataaaaa agaacatgct tcaggagact ctgtggtttc ccctcttcct gtaaccactg1441 tgaaatcggt taaccttaga caaagtgaga acacttctgc taatgagaag gaggtggagg1501 cagaatttct cagattatct ttgggattta agtgtgactg gtttaccttg gagaagagag1561 tgaagcttga agagaggtcc cgtgacttgg cagaagaaaa tttgaagaaa gaaatcacta
1621 actgtttaaa actattagag tctttaacac ctctgtgtga agatgacaac caggcacagg1681 aaatcattaa gaagctggag aagagtataa agtttcttag ccagtgtgcag cacgagtgg1741 ccagtagggc tgagatgttg ggagccatca atcaggaaag ccgggttagt aaagcagttg1801 aagtgatgat tcagcacgta gaaaacttga agaggatgta tgccaaagag cacgctgaat1861 tagaagaact gaaacaggtt cttctgcaga atgaaaggtc tttcaatcct cttgaagatg1921 atgatgactg ccaaattaaa aaacgttcag cttctctaaa ctccaagcca tcttctctac1981 gaagagtgac tattgcctct ttacccagaa atattggaaa tgcaggaatg gtggctggga2041 tggaaaataa tgatcgattc agtagaaggt caagcagttg gcgtattttg gggtcaaagc2101 agagtgaaca ccgtccctca ttacctcgat ttattagcac ctattcctgg gcagatgctg2161 aagaagaaaa atgtgaacta aaaactaaag atgactcaga gccatctgga gaagaaacag2221 tagaaaggac aaggaagcca agtctttctg aaaagaaaaa taatccatca aagtgggatg2281 tctcttcagt ttatgacaca atagcttcct gggcaacaaa tctcaagtcc tccatcagaa2341 aggctaataa ggccctctgg ctctctattg cattcattgt actgtttgca gctttgatga2401 gcttcctcac aggccaatta ttccagaagt ctgtggatgc cgctcccaca cagcaagagg2461 actcatggac gtctctagaa catatcttgt ggccatttac cagactccga cacaatgggc2521 caccaccagt gtgacagcag gacatcctaa tatatggatc ttgattttta agtttcagta2581 tctgaacttc gtaaattagt aacttttagc tgggaaagta tagcatgaaa ccagaggttc2641 tcagaatgac tgtaagatag cttacatttc ctctttttgc ctttatctcc ccaactaaaa2701 tacaatgggg aagaagtctg cctatgatct ttgaatgagc tttttaagga agaaatatta2761 tatattgttt gttaaagttt attgaaataa agaatcattt aaatcttcaa aaaaaaaaaa2821 aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>8<211>1984<212>DNA<213>人類(Homo sapiens)<400>81 ctgatttaca ggaactcaca ccagcgatca atcttcctta atttgtaact gggcagtgtc61 ccgggccagc caatagctaa gactgccccc cccgcacccc accctccctg accctggggg121 actctctact cagtctgcac tggagctgcc tggtgaccag aagtttggag tccgctgacg181 tcgccgccca gatggcctcc aggctgaccc tgctgaccct cctgctgctg ctgctggctg241 gggatagagc ctcctcaaat ccaaatgcta ccagctccag ctcccaggat ccagagagtt301 tgcaagacag aggcgaaggg aaggtcgcaa caacagttat ctccaagatg ctattcgttg361 aacccatcct ggaggtttcc agcttgccga caaccaactc aacaaccaat tcagccacca421 aaataacagc taataccact gatgaaccca ccacacaacc caccacagag cccaccaccc481 aacccaccat ccaacccacc caaccaacta cccagctccc aacagattct cctacccagc541 ccactactgg gtccttctgc ccaggacctg ttactctctg ctctgacttg gagagtcatt601 caacagaggc cgtgttgggg gatgctttgg tagatttctc cctgaagctc taccacgcct661 tctcagcaat gaagaaggtg gagaccaaca tggccttttc cccattcagc atcgccagcc721 tccttaccca ggtcctgctc ggggctgggg agaacaccaa aacaaacctg gagagcatcc781 tctcttaccc caaggacttc acctgtgtcc accaggccct gaagggcttc acgaccaaag841 gtgtcacctc agtctctcag atcttccaca gcccagacct ggccataagg gacacctttg901 tgaatgcctc tcggaccctg tacagcagca gccccagagt cctaagcaac aacagtgacg961 ccaacttgga gctcatcaac acctgggtgg ccaagaacac caacaacaag atcagccggc1021 tgctagacag tctgccctcc gatacccgcc ttgtcctcct caatgctatc tacctgagtg
1081 ccaagtggaa gacaacattt gatcccaaga aaaccagaat ggaacccttt cacttcaaaa1141 actcagttat aaaagtgccc atgatgaata gcaagaagta ccctgtggcc catttcattg1201 accaaacttt gaaagccaag gtggggcagc tgcagctctc ccacaatctg agtttggtga1261 tcctggtacc ccagaacctg aaacatcgtc ttgaagacat ggaacaggct ctcagccctt1321 ctgttttcaa ggccatcatg gagaaactgg agatgtccaa gttccagccc actctcctaa1381 cactaccccg catcaaagtg acgaccagcc aggatatgct ctcaatcatg gagaaattgg1441 aattcttcga tttttcttat gaccttaacc tgtgtgggct gacagaggac ccagatcttc1501 aggtttctgc gatgcagcac cagacagtgc tggaactgac agagactggg gtggaggcgg1561 ctgcagcctc cgccatctct gtggcccgca ccctgctggt ctttgaagtg cagcagccct1621 tcctcttcgt gctctgggac cagcagcaca agttccctgt cttcatgggg cgagtatatg1681 accccagggc ctgagacctg caggatcagg ttagggcgag cgctacctct ccagcctcag1741 ctctcagttg cagccctgct gctgcctgcc tggacttggc ccctgccacc tcctgcctca1801 ggtgtccgct atccaccaaa agggctccct gagggtctgg gcaagggacc tgcttctatt1861 agcccttctc catggccctg ccatgctctc caaaccactt tttgcagctt tctctagttc1921 aagttcacca gactctataa ataaaacctg acagaccatg actttcaaaa aaaaaaaaaa1981 aaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>9<211>2360<212>DNA<213>人類(Homo sapiens)<400>91 acagtgcgga gaccgcagcc ccggagcccg ggccagggtc cacctgtccc cgcagcgccg61 gctcgcgccc tcctgccgca gccaccgagc cgccgtctag cgccccgacc tcgccaccat121 gagagccctg ctggcgcgcc tgcttctctg cgtcctggtc gtgagcgact ccaaaggcag181 caatgaactt catcaagttc catcgaactg tgactgtcta aatggaggaa catgtgtgtc241 caacaagtac ttctccaaca ttcactggtg caactgccca aagaaattcg gagggcagca301 ctgtgaaata gataagtcaa aaacctgcta tgaggggaat ggtcactttt accgaggaaa361 ggccagcact gacaccatgg gccggccctg cctgccctgg aactctgcca ctgtccttca421 gcaaacgtac catgcccaca gatctgatgc tcttcagctg ggcctgggga aacataatta481 ctgcaggaac ccagacaacc ggaggcgacc ctggtgctat gtgcaggtgg gcctaaagcc541 gcttgtccaa gagtgcatgg tgcatgactg cgcagatgga aaaaagccct cctctcctcc601 agaagaatta aaatttcagt gtggccaaaa gactctgagg ccccgcttta agattattgg661 gggagaattc accagcatcg agaaccagcc ctggtttgcg gccatctaca ggaggcaccg721 ggggggctct gtcacctacg tgtgtggagg cagcctcatc agcccttgct gggtgatcag781 cgccacacac tgcttcattg attacccaaa gaaggaggac tacatcgtct acctgggtcg841 ctcaaggctt aactccaaca cgcaagggga gatgaagttt gaggtggaaa acctcatcct901 acacaaggac tacagcgctg acacgcttgc tcaccacaac gacattgcct tgctgaagat961 ccgttccaag gagggcaggt gtgcgcagcc atcccggact atacagacca tctgcctgcc1021 ctcgatgtat aacgatcccc agtttggcac aagctgtgag atcactggct ttggaaaaga1081 gaattctacc gactatctct atccggagca gctgaaaatg actgttgtga agctgatttc1141 ccaccgggag tgtcagcagc cccactacta cggctctgaa gtcaccacca aaatgctgtg1201 tgctgctgac ccacagtgga aaacagattc ctgccaggga gactcagggg gacccctcgt1261 ctgttccctc caaggccgca tgactttgac tggaattgtg agctggggcc gtggatgtgc1321 cctgaaggac aagccaggcg tctacacgag agtctcacac ttcttaccct ggatccgcag
1381 tcacaccaag gaagagaatg gcctggccct ctgagggtcc ccagggagga aacgggcacc1441 acccgctttc ttgctggttg tcatttttgc agtagagtca tctccatcag ctgtaagaag1501 agactgggaa gataggctct gcacagatgg atttgcctgt gccacccacc agggcgaacg1561 acaatagctt taccctcagg cataggcctg ggtgctggct gcccagaccc ctctggccag1621 gatggagggg tggtcctgac tcaacatgtt actgaccagc aacttgtctt tttctggact1681 gaagcctgca ggagttaaaa agggcagggc atctcctgtg catgggtgaa gggagagcca1741 gctcccccga cggtgggcat ttgtgaggcc catggttgag aaatgaataa tttcccaatt1801 aggaagtgta acagctgagg tctcttgagg gagcttagcc aatgtgggag cagcggtttg1861 gggagcagag acactaacga cttcagggca gggctctgat attccatgaa tgtatcagga1921 aatatatatg tgtgtgtatg tttgcacact tgtgtgtggg ctgtgagtgt aagtgtgagt1981 aagagctggt gtctgattgt taagtctaaa tatttcctta aactgtgtgg actgtgatgc2041 cacacagagt ggtctttctg gagaggttat aggtcactcc tggggcctct tgggtccccc2101 acgtgacagt gcctgggaat gtattattct gcagcatgac ctgtgaccag cactgtctca2161 gtttcacttt cacatagatg tccctttctt ggccagttat cccttccttt tagcctagtt2221 catccaatcc tcactgggtg gggtgaggac cactcctgta cactgaatat ttatatttca2281 ctatttttat ttatattttt gtaattttaa ataaaagtga tcaataaaat gtgatttttc2341 tgatgaaaaa aaaaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>10<211>1616<212>DNA<213>人類(Homo sapiens)<400>101 ctccctgtgt tggtggagga tgtctgcagc agcatttaaa ttctgggagg gcttggttgt61 cagcagcagc aggaggaggc agagcacagc atcgtcggga ccagactcgt ctcaggccag121 ttgcagcctt ctcagccaaa cgccgaccaa ggaaaactca ctaccatgag aattgcagtg181 atttgctttt gcctcctagg catcacctgt gccataccag ttaaacaggc tgattctgga241 agttctgagg aaaagcagct ttacaacaaa tacccagatg ctgtggccac atggctaaac301 cctgacccat ctcagaagca gaatctccta gccccacaga cccttccaag taagtccaac361 gaaagccatg accacatgga tgatatggat gatgaagatg atgatgacca tgtggacagc421 caggactcca ttgactcgaa cgactctgat gatgtagatg acactgatga ttctcaccag481 tctgatgagt ctcaccattc tgatgaatct gatgaactgg tcactgattt tcccacggac541 ctgccagcaa ccgaagtttt cactccagtt gtccccacag tagacacata tgatggccga601 ggtgatagtg tggtttatgg actgaggtca aaatctaaga agtttcgcag acctgacatc661 cagtaccctg atgctacaga cgaggacatc acctcacaca tggaaagcga ggagttgaat721 ggtgcataca aggccatccc cgttgcccag gacctgaacg cgccttctga ttgggacagc781 cgtgggaagg acagttatga aacgagtcag ctggatgacc agagtgctga aacccacagc841 cacaagcagt ccagattata taagcggaaa gccaatgatg agagcaatga gcattccgat901 gtgattgata gtcaggaact ttccaaagtc agccgtgaat tccacagcca tgaatttcac961 agccatgaag atatgctggt tgtagacccc aaaagtaagg aagaagataa agacctgaaa1021 tttcgtattt ctcatgaatt agatagtgca tcttctgagg tcaattaaaa ggagaaaaaa1081 tacaatttct cactttgcat ttagtcaaaa gaaaaaatgc tttatagcaa aatgaaagag1141 aacatgaaat gcttctttct cagtttattg gttgaatgtg tatctatttg agtctggaaa1201 taactaatgt gtttgataat tagtttagtt tgtggcttca tggaaactcc ctgtaaacta1261 aaagcttcag ggttatgtct atgttcattc tatagaagaa atgcaaacta tcactgtatt
1321 ttaatatttg ttattctctc atgaatagaa atttatgtag aagcaaacaa aatactttta1381 cccacttaaa aagagaatat aacattttat gtcactataa tcttctgttt tttaagttag1441 tgtatatttt gttgtgatta tctttttgtg gtgtgaataa atcttttatc ttgaatgtaa1501 taagaatttg gtggtgtcaa ttgcttattt gttttcccac ggttgtccag caattaataa1561 aacataacct tttttactgc ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>11<211>1483<212>DNA<213>人類(Homo sapiens)<400>111 gacacagtag aaataacact ttataagcct cttcctcctc ccatctcctg gcctccttcc61 atcctcctct gcccagactc cgcccctccc agacggtcct cacttctctt ttccctagac121 tgcagccagc ggagcccgca gccggcccga gccaggaacc caggtccgga gcctcaactt181 caggatgttg acaacattgc tgccgatact gctgctgtct ggctgggcct tttgtagcca241 agacgcctca gatggcctcc aaagacttca tatgctccag atctcctact tccgcgaccc301 ctatcacgtg tggtaccagg gcaacgcgtc gctgggggga cacctaacgc acgtgctgga361 aggcccagac accaacacca cgatcattca gctgcagccc ttgcaggagc ccgagagctg421 ggcgcgcacg cagagtggcc tgcagtccta cctgctccag ttccacggcc tcgtgcgcct481 ggtgcaccag gagcggacct tggcctttcc tctgaccatc cgctgcttcc tgggctgtga541 gctgcctccc gagggctcta gagcccatgt cttcttcgaa gtggctgtga atgggagctc601 ctttgtgagt ttccggccgg agagagcctt gtggcaggca gacacccagg tcacctccgg661 agtggtcacc ttcaccctgc agcagctcaa tgcctacaac cgcactcggt atgaactgcg721 ggaattcctg gaggacacct gtgtgcagta tgtgcagaaa catatttccg cggaaaacac781 gaaagggagc caaacaagcc gctcctacac ttcgctggtc ctgggcgtcc tggtgggcag841 tttcatcatt gctggtgtgg ctgtaggcat cttcctgtgc acaggtggac ggcgatgtta901 attactctcc agccccctca gaaggggctg gattgatgga ggctggcaag ggaaagtttc961 agctcactgt gaagccagac tccccaactg aaacaccaga aggtttggag tgacagctcc1021 tttcttctcc cacatctgcc cactgaagat ttgagggagg ggagatggag aggagaggtg1081 gacaaagtac ttggtttgct aagaacctaa gaacgtgtat gctttgctga attagtctga1141 taagtgaatg tttatctatc tttgtggaaa acagataatg gagttggggc aggaagccta1201 tggcccatcc tccaaagaca gacagaatca cctgaggcgt tcaaaagata taaccaaata1261 aacaagtcat ccacaatcaa aatacaacat tcaatacttc caggtgtgtc agacttggga1321 tgggacgctg atataatagg gtagaaagaa gtaacacgaa gaagtggtgg aaatgtaaaa1381 tccaagtcat atggcagtga tcaattatta atcaattaat aatattaata aatttcttat1441 atttaaggca aaaaaaaaat aaaaaaaaaa aaaaaaaaaa aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>12<211>4221<212>DNA<213>人類(Homo sapiens)<400>12
1 ataactttgt agcgagtcga aaactgaggc tccggccgca gagaactcag cctcattcct61 gctttaaaat ctctcggcca cctttgatga ggggactggg cagttctaga cagtcccgaa121 gttctcaagg cacaggtctc ttcctggttt gactgtcctt accccgggga ggcagtgcag181 ccagctgcaa gccccacagt gaagaacatc tgagctcaaa tccagataag tgacataagt241 gacctgcttt gtaaagccat agagatggcc tgtccttgga aatttctgtt caagaccaaa301 ttccaccagt atgcaatgaa tggggaaaaa gacatcaaca acaatgtgga gaaagccccc361 tgtgccacct ccagtccagt gacacaggat gaccttcagt atcacaacct cagcaagcag421 cagaatgagt ccccgcagcc cctcgtggag acgggaaaga agtctccaga atctctggtc481 aagctggatg caaccccatt gtcctcccca cggcatgtga ggatcaaaaa ctggggcagc541 gggatgactt tccaagacac acttcaccat aaggccaaag ggattttaac ttgcaggtcc601 aaatcttgcc tggggtccat tatgactccc aaaagtttga ccagaggacc cagggacaag661 cctacccctc cagatgagct tctacctcaa gctatcgaat ttgtcaacca atattacggc721 tccttcaaag aggcaaaaat agaggaacat ctggccaggg tggaagcggt aacaaaggag781 atagaaacaa caggaaccta ccaactgacg ggagatgagc tcatcttcgc caccaagcag841 gcctggcgca atgccccacg ctgcattggg aggatccagt ggtccaacct gcaggtcttc901 gatgcccgca gctgttccac tgcccgggaa atgtttgaac acatctgcag acacgtgcgt961 tactccacca acaatggcaa catcaggtcg gccatcaccg tgttccccca gcggagtgat1021 ggcaagcacg acttccgggt gtggaatgct cagctcatcc gctatgctgg ctaccagatg1081 ccagatggca gcatcagagg ggaccctgcc aacgtggaat tcactcagct gtgcatcgac1141 ctgggctgga agcccaagta cggccgcttc gatgtggtcc ccctggtcct gcaggccaat1201 ggccgtgacc ctgagctctt cgaaatccca cctgaccttg tgcttgaggt ggccatggaa1261 catcccaaat acgagtggtt tcgggaactg gagctaaagt ggtacgccct gcctgcagtg1321 gccaacatgc tgcttgaggt gggcggcctg gagttcccag ggtgcccctt caatggctgg1381 tacatgggca cagagatcgg agtccgggac ttctgtgacg tccagcgcta caacatcctg1441 gaggaagtgg gcaggagaat gggcctggaa acgcacaagc tggcctcgct ctggaaagac1501 caggctgtcg ttgagatcaa cattgctgtg ctccatagtt tccagaagca gaatgtgacc1561 atcatggacc accactcggc tgcagaatcc ttcatgaagt acatgcagaa tgaataccgg1621 tcccgtgggg gctgcccggc agactggatt tggctggtcc ctcccatgtc tgggagcatc1681 acccccgtgt ttcaccagga gatgctgaac tacgtcctgt cccctttcta ctactatcag1741 gtagaggcct ggaaaaccca tgtctggcag gacgagaagc ggagacccaa gagaagagag1801 attccattga aagtcttggt caaagctgtg ctctttgcct gtatgctgat gcgcaagaca1861 atggcgtccc gagtcagagt caccatcctc tttgcgacag agacaggaaa atcagaggcg1921 ctggcctggg acctgggggc cttattcagc tgtgccttca accccaaggt tgtctgcatg1981 gataagtaca ggctgagctg cctggaggag gaacggctgc tgttggtggt gaccagtacg2041 tttggcaatg gagactgccc tggcaatgga gagaaactga agaaatcgct cttcatgctg2101 aaagagctca acaacaaatt caggtacgct gtgtttggcc tcggctccag catgtaccct2161 cggttctgcg cctttgctca tgacattgat cagaagctgt cccacctggg ggcctctcag2221 ctcaccccga tgggagaagg ggatgagctc agtgggcagg aggacgcctt ccgcagctgg2281 gccgtgcaaa ccttcaaggc agcctgtgag acgtttgatg tccgaggcaa acagcacatt2341 cagatcccca agctctacac ctccaatgtg acctgggacc cgcaccacta caggctcgtg2401 caggactcac agcctttgga cctcagcaaa gccctcagca gcatgcatgc caagaacgtg2461 ttcaccatga ggctcaaatc tcggcagaat ctacaaagtc cgacatccag ccgtgccacc2521 atcctggtgg aactctcctg tgaggatggc caaggcctga actacctgcc gggggagcac2581 cttggggttt gcccaggcaa ccagccggcc ctggtccaag gtatcctgga gcgagtggtg2641 gatggcccca caccccacca gacagtgcgc ctggaggccc tggatgagag tggcagctac2701 tgggtcagtg acaagaggct gcccccctgc tcactcagcc aggccctcac ctacttcctg2761 gacatcacca cacccccaac ccagctgctg ctccaaaagc tggcccaggt ggccacagaa2821 gagcctgaga gacagaggct ggaggccctg tgccagccct cagagtacag caagtggaag
2881 ttcaccaaca gccccacatt cctggaggtg ctagaggagt tcccgtccct gcgggtgtct2941 gctggcttcc tgctttccca gctccccatt ctgaagccca ggttatactc catcagctcc3001 tcccgggatc acacgcccac agagatccac ctgactgtgg ccgtggtcac ctaccacacc3061 cgagatggcc agggtcccct gcaccacggc gtctgcagca catggctcaa cagcctgaag3121 ccccaagacc cagtgccctg ctttgtgcgg aatgccagcg gcttccacct ccccgaggat3181 ccctcccatc cttgcatcct catcgggcct ggcacaggca tcgcgccctt ccgcagtttc3241 tggcagcaac ggctccatga ctcccagcac aagggagtgc ggggaggccg catgaccttg3301 gtgtttgggt gccgccgccc agatgaggac cacatctacc aggaggagat gctggagatg3361 gcccagaagg gggtgctgca tgcggtgcac acagcctatt cccgcctgcc tggcaagccc3421 aaggtctatg ttcaggacat cctgcggcag cagctggcca gcgaggtgct ccgtgtgctc3481 cacaaggagc caggccacct ctatgtttgc ggggatgtgc gcatggcccg ggacgtggcc3541 cacaccctga agcagctggt ggctgccaag ctgaaattga atgaggagca ggtcgaggac3601 tatttctttc agctcaagag ccagaagcgc tatcacgaag atatctttgg tgctgtattt3661 ccttacgagg cgaagaagga cagggtggcg gtgcagccca gcagcctgga gatgtcagcg3721 ctctgagggc ctacaggagg ggttaaagct gccggcacag aacttaagga tggagccagc3781 tctgcattat ctgaggtcac agggcctggg gagatggagg aaagtgatat cccccagcct3841 caagtcttat ttcctcaacg ttgctcccca tcaagccctt tacttgacct cctaacaagt3901 agcaccctgg attgatcgga gcctcctctc tcaaactggg gcctccctgg tcccttggag3961 acaaaatctt aaatgccagg cctggcaagt gggtgaaaga tggaacttgc tgctgagtgc4021 accacttcaa gtgaccacca ggaggtgcta tcgcaccact gtgtatttaa ctgccttgtg4081 tacagttatt tatgcctctg tatttaaaaa actaacaccc agtctgttcc ccatggccac4141 ttgggtcttc cctgtatgat tccttgatgg agatatttac atgaattgca ttttacttta4201 atcacaaaaa aaaaaaaaaa a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>13<211>2601<212>DNA<213>人類(Homo sapiens)<400>131 ccgcccttgt aggctgtcca cctcaaacgg gccggacagg atatataaga gagaatgcac61 cgtgcactac acacgcgact cccacaaggt tgcagccgga gccgcccagc tcaccgagag121 cctagttccg gccagggtcg ccccggcaac cacgagccca gccaatcagc gccccggact181 gcaccagagc catggtcggc agaagagcac tgatcgtact ggctcactca gagaggacgt241 ccttcaacta tgccatgaag gaggctgctg cagcggcttt gaagaagaaa ggatgggagg301 tggtggagtc ggacctctat gccatgaact tcaatcccat catttccaga aaggacatca361 caggtaaact gaaggaccct gcgaactttc agtatcctgc cgagtctgtt ctggcttata421 aagaaggcca tctgagccca gatattgtgg ctgaacaaaa gaagctggaa gccgcagacc481 ttgtgatatt ccagttcccc ctgcagtggt ttggagtccc tgccattctg aaaggctggt541 ttgagcgagt gttcatagga gagtttgctt acacttacgc tgccatgtat gacaaaggac601 ccttccggag taagaaggca gtgctttcca tcaccactgg tggcagtggc tccatgtact661 ctctgcaagg gatccacggg gacatgaatg tcattctctg gccaattcag agtggcattc721 tgcatttctg tggcttccaa gtcttagaac ctcaactgac atatagcatt gggcacactc781 cagcagacgc ccgaattcaa atcctggaag gatggaagaa acgcctggag aatatttggg841 atgagacacc actgtatttt gctccaagca gcctctttga cctaaacttc caggcaggat901 tcttaatgaa aaaagaggta caggatgagg agaaaaacaa gaaatttggc ctttctgtgg
961 gccatcactt gggcaagtcc atcccaactg acaaccagat caaagctaga aaatgagatt1021 ccttagcctg gatttccttc taacatgtta tcaaatctgg gtatctttcc aggcttccct1081 gacttgcttt agtttttaag atttgtgttt ttctttttcc acaaggaata aatgagaggg1141 aatcgactgt attcgtgcat ttttggatca tttttaactg attcttatga ttactatcat1201 ggcatataac caaaatccga ctgggctcaa gaggccactt agggaaagat gtagaaagat1261 gctagaaaaa tgttctttaa aggcatctac acaatttaat tcctcttttt agggctaaag1321 ttttagggta cagtttggct aggtatcatt caactctcca atgttctatt aatcacctct1381 ctgtagttta tggcagaagg gaattgctca gagaaggaaa agactgaatc tacctgccct1441 aagggactta acttgtttgg tagttagcca tctaatgctt gtttatgata tttcttgctt1501 tcaattacaa agcagttact aatatgccta gcacaagtac cactcttggt cagcttttgt1561 tgtttatata cagtacacag ataccttgaa aggaagagct aataaatctc ttctttgctg1621 cagtcatcta cttttttttt aattaaaaaa aatttttttt tgaagcagtc ttgctctgtt1681 acccaggctg gagtgcagtg gtgtgatctc ggctcactgc aacctctgcc tcccaggttc1741 cagcaattct cctgcctcag cctccctagt agctgggatg acaggcgcct gccatcatgc1801 ctgactaatt tttgtatttt tagtagagac ggcgtttcac catgttggcc aggctggtct1861 caaactcctg acctcaggtg atccgcctac ctcagcctcc caaagtgctg ggattacagg1921 cgtgatccac cacacctggc ccttgcaatc ttctacttta aggtttgcag agataaacca1981 ataaatccac accgtacatc tgcaatatga attcaagaaa ggaaatagta ccttcaatac2041 ttaaaaatag tcttccacaa aaaatacttt atttctgatc tatacaaatt ttcagaaggt2101 tattttcttt atcattgcta aactgatgac ttactatggg atggggtcca gtcccatgac2161 cttggggtac aattgtaaac ctagagtttt atcaactttg gtgaacagtt ttggcataat2221 agtcaatttc tacttctgga agtcatctca ttccactgtt ggtattatat aattcaagga2281 gaatatgata aaacactgcc ctcttgtggt gcattgaaag aagagatgag aaatgatgaa2341 aaggttgcct gaaaaatggg agacagcctc ttacttgcca agaaaatgaa gggattggac2401 cgagctggaa aacctccttt accagatgct gactggcact ggtggttttt gctctcgaca2461 gtatccacaa tagctgacgg ctgggtgttt cagtttgaaa atattttgtt gccttcatct2521 tcactgcaat tttgtgtaaa tttctcaaag atctgaatta aataaataaa attcatttct2581 acagacccac aaaaaaaaaa a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>14<211>2175<212>DNA<213>人類(Homo sapiens)<400>141 agtacagtat aaaacttcac agtgccaata ccatgaagag gagctcagac agctcttacc61 acatgataca agagccggct ggtggaagag tggggaccag aaagagaatt tgctgaagag121 gagaaggaaa aaaaaaacac caaaaaaaaa aataaaaaaa tccacacaca caaaaaaacc181 tgcgcgtgag gggggaggaa aagcagggcc ttttaaaaag gcaatcacaa caacttttgc241 tgccaggatg cccttgcttt ggctgagagg atttctgttg gcaagttgct ggattatagt301 gaggagttcc cccaccccag gatccgaggg gcacagcgcg gcccccgact gtccgtcctg361 tgcgctggcc gccctcccaa aggatgtacc caactctcag ccagagatgg tggaggccgt421 caagaagcac attttaaaca tgctgcactt gaagaagaga cccgatgtca cccagccggt481 acccaaggcg gcgcttctga acgcgatcag aaagcttcat gtgggcaaag tcggggagaa541 cgggtatgtg gagatagagg atgacattgg aaggagggca gaaatgaatg aacttatgga601 gcagacctcg gagatcatca cgtttgccga gtcaggaaca gccaggaaga cgctgcactt
661 cgagatttcc aaggaaggca gtgacctgtc agtggtggag cgtgcagaag tctggctctt721 cctaaaagtc cccaaggcca acaggactag gaccaaagtt accatccgcc tcttccagca781 gcagaagcac ccgcagggca gcttggacac aggggaagag gccgaggaag tgggcttaaa841 gggggagagg agtgaactgt tgctctctga aaaagtagta gacgctcgga agagcacctg901 gcatgtcttc cctgtctcca gcagcatcca gcggttgctg gaccagggca agagctccct961 ggacgttcgg attgcctgtg agcagtgcca ggagagtggc gccagcttgg ttctcctggg1021 caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag gtgaaggtgg1081 ggcaggagca gatgaggaaa aggagcagtc gcacagacct ttcctcatgc tgcaggcccg1141 gcagtctgaa gaccaccctc atcgccggcg tcggcggggc ttggagtgtg atggcaaggt1201 caacatctgc tgtaagaaac agttctttgt cagtttcaag gacatcggct ggaatgactg1261 gatcattgct ccctctggct atcatgccaa ctactgcgag ggtgagtgcc cgagccatat1321 agcaggcacg tccgggtcct cactgtcctt ccactcaaca gtcatcaacc actaccgcat1381 gcggggccat agcccctttg ccaacctcaa atcgtgctgt gtgcccacca agctgagacc1441 catgtccatg ttgtactatg atgatggtca aaacatcatc aaaaaggaca ttcagaacat1501 gatcgtggag gagtgtgggt gctcatagag ttgcccagcc cagggggaaa gggagcaaga1561 gttgtccagg gaagacagtg gcaaaatgaa gaaattttta aggtttctga gttaaccaga1621 aaaatagaaa ttaaaaacaa aacaaaaaaa aaaacaaaaa aaaacaaaag taaattaaaa1681 acaaaacctg atgaaacaga tgaaggaaga tgtggaaaaa atccttagcc agggctcaga1741 gatgaagcag tgaaagagac aggaattggg agggaaaggg agaatggtgt accctttatt1801 tcttctgaaa tcacactgat gacatcagtt gtttaaacgg ggtattgtcc tttcccccct1861 tgaggttccc ttgtgagcct tgaatcaacc aatctagtct gcagtagtgt ggactagaac1921 aacccaaata gcatctagaa agccatgagt ttgaaagggc ccatcacagg cactttccta1981 cccaattacc caggtcataa ggtatgtctg tgtgacactt atctctgtgt atatcagcat2041 acacacacac acacacacac acacacacac acacaggcat ttccacacat tacatatata2101 cacatactgg taaaagaaca atcgtgtgca ggtggtcaca cttccttttt ctgtaccact2161 tttgcaacaa aacaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>15<211>2305<212>DNA<213>人類(Homo sapiens)<400>151 ttcttggggc tgatgtccgc aaatatgcag aattaccggc cgggtcgctc ctgaagccag61 cgcggggagc gagcgcggcg gcggccagca ccgggaacgc accgaggaag aagcccagcc121 cccgccctcc gccccttccg tccccacccc ctacccggcg gcccaggagg ctccccggct181 gcggcgcgca ctccctgttt ctcctcctcc tggctggcgc tgcctgcctc tccgcactca241 ctgctcgccg ggcgccgtcc gccagctccg tgctccccgc gccaccctcc tccgggccgc301 gctccctaag ggatggtact gaatttcgcc gccacaggag accggctgga gcgcccgccc361 cgcgcctcgc ctctcctccg agcagccagc gcctcgggac gcgatgagga ccttggcttg421 cctgctgctc ctcggctgcg gatacctcgc ccatgttctg gccgaggaag ccgagatccc481 ccgcgaggtg atcgagaggc tggcccgcgg tcagatccac agcatccggg acctccagcg541 actcctggag atagactccg tagggagtga ggattctttg gacaccagcc tgagagctca601 cggggtccac gccactaagc atgtgcccga gaagcggccc ctgcccattc ggaggaagag661 aagcatcgag gaagctgtcc ccgctgtctg caagaccagg acggtcattt acgagattcc721 tcggagtcag gtcgacccca cgtccgccaa cttcctgatc tggcccccgt gcgtggaggt
781 gaaacgctgc accggctgct gcaacacgag cagtgtcaag tgccagccct cccgcgtcca841 ccaccgcagc gtcaaggtgg ccaaggtgga atacgtcagg aagaagccaa aattaaaaga901 agtccaggtg aggttagagg agcatttgga gtgcgcctgc gcgaccacaa gcctgaatcc961 ggattatcgg gaagaggaca cggatgtgag gtgaggatga gccgcagccc tttcctggga1021 catggatgta catggcgtgt tacattcctg aacctactat gtacggtgct ttattgccag1081 tgtgcggtct ttgttctcct ccgtgaaaaa ctgtgtccga gaacactcgg gagaacaaag1141 agacagtgca catttgttta atgtgacatc aaagcaagta ttgtagcact cggtgaagca1201 gtaagaagct tccttgtcaa aaagagagag agagagagag agagagaaaa caaaaccaca1261 aatgacaaaa acaaaacgga ctcacaaaaa tatctaaact cgatgagatg gagggtcgcc1321 ccgtgggatg gaagtgcaga ggtctcagca gactggattt ctgtccgggt ggtcacaggt1381 gcttttttgc cgaggatgca gagcctgctt tgggaacgac tccagagggg tgctggtggg1441 ctctgcaggg cccgcaggaa gcaggaatgt cttggaaacc gccacgcgaa ctttagaaac1501 cacacctcct cgctgtagta tttaagccca tacagaaacc ttcctgagag ccttaagtgg1561 tttttttttt tgtttttgtt ttgttttttt tttttttgtt tttttttttt tttttttttt1621 ttacaccata aagtgattat taagcttcct tttactcttt ggctagcttt tttttttttt1681 tttttttttt ttttttttaa ttatctcttg gatgacattt acaccgataa cacacaggct1741 gctgtaactg tcaggacagt gcgacggtat ttttcctagc aagatgcaaa ctaatgagat1801 gtattaaaat aaacatggta tacctaccta tgcatcattt cctaaatgtt tctggctttg1861 tgtttctccc ttaccctgct ttatttgtta atttaagcca ttttgaaaga actatgcgtc1921 aaccaatcgt acgccgtccc tgcggcacct gccccagagc ccgtttgtgg ctgagtgaca1981 acttgttccc cgcagtgcac acctagaatg ctgtgttccc acgcggcacg tgagatgcat2041 tgccgcttct gtctgtgttg ttggtgtgcc ctggtgccgt ggtggcggtc actccctctg2101 ctgccagtgt ttggacagaa cccaaattct ttatttttgg taagatattg tgctttacct2161 gtattaacag aaatgtgtgt gtgtggtttg tttttttgta aaggtgaagt ttgtatgttt2221 acctaatatt acctgttttg tatacctgag agcctgctat gttcttcttt tgttgatcca2281 aaattaaaaa aaaaatacca ccaac<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>16<211>3373<212>DNA<213>人類(Homo sapiens)<400>161 ggtggcaact tctcctcctg cggccgggag cggcctgcct gcctccctgc gcacccgcag61 cctcccccgc tgcctcccta gggctcccct ccggccgcca gcgcccattt ttcattccct121 agatagagat actttgcgcg cacacacata catacgcgcg caaaaaggaa aaaaaaaaaa181 aaaagcccac cctccagcct cgctgcaaag agaaaaccgg agcagccgca gctcgcagct241 cgcagctcgc agcccgcagc ccgcagagga cgcccagagc ggcgagcagg cgggcagacg301 gaccgacgga ctcgcgccgc gtccacctgt cggccgggcc cagccgagcg cgcagcgggc361 acgccgcgcg cgcggagcag ccgtgcccgc cgcccgggcc cgccgccagg gcgcacacgc421 tcccgccccc ctacccggcc cgggcgggag tttgcacctc tccctgcccg ggtgctcgag481 ctgccgttgc aaagccaact ttggaaaaag ttttttgggg gagacttggg ccttgaggtg541 cccagctccg cgctttccga ttttgggggc ctttccagaa aatgttgcaa aaaagctaag601 ccggcgggca gaggaaaacg cctgtagccg gcgagtgaag acgaaccatc gactgccgtg661 ttccttttcc tcttggaggt tggagtcccc tgggcgcccc cacacggcta gacgcctcgg721 ctggttcgcg acgcagcccc ccggccgtgg atgctgcact cgggctcggg atccgcccag
781 gtagccggcc tcggacccag gtcctgcgcc caggtcctcc cctgccccct agcgacggag841 ccggggccgg gggcggcggc gccgggggca tgcgggtgag ccgcggctgc agaggcctga901 gcgcctgatc gccgcggacc tgagccgagc ccacccccct ccccagcccc ccaccctggc961 cgcgggggcg gcgcgctcga tctacgcgtc cggggccccg cggggccggg cccggagtcg1021 gcatgaatcg ctgctgggcg ctcttcctgt ctctctgctg ctacctgcgt ctggtcagcg1081 ccgaggggga ccccattccc gaggagcttt atgagatgct gagtgaccac tcgatccgct1141 cctttgatga tctccaacgc ctgctgcacg gagaccccgg agaggaagat ggggccgagt1201 tggacctgaa catgacccgc tcccactctg gaggcgagct ggagagcttg gctcgtggaa1261 gaaggagcct gggttccctg accattgctg agccggccat gatcgccgag tgcaagacgc1321 gcaccgaggt gttcgagatc tcccggcgcc tcatagaccg caccaacgcc aacttcctgg1381 tgtggccgcc ctgtgtggag gtgcagcgct gctccggctg ctgcaacaac cgcaacgtgc1441 agtgccgccc cacccaggtg cagctgcgac ctgtccaggt gagaaagatc gagattgtgc1501 ggaagaagcc aatctttaag aaggccacgg tgacgctgga agaccacctg gcatgcaagt1561 gtgagacagt ggcagctgca cggcctgtga cccgaagccc ggggggttcc caggagcagc1621 gagccaaaac gccccaaact cgggtgacca ttcggacggt gcgagtccgc cggcccccca1681 agggcaagca ccggaaattc aagcacacgc atgacaagac ggcactgaag gagacccttg1741 gagcctaggg gcatcggcag gagagtgtgt gggcagggtt atttaatatg gtatttgctg1801 tattgccccc atggggtcct tggagtgata atattgtttc cctcgtccgt ctgtctcgat1861 gcctgattcg gacggccaat ggtgcttccc ccacccctcc acgtgtccgt ccacccttcc1921 atcagcgggt ctcctcccag cggcctccgg tcttgcccag cagctcaaag aagaaaaaga1981 aggactgaac tccatcgcca tcttcttccc ttaactccaa gaacttggga taagagtgtg2041 agagagactg atggggtcgc tctttggggg aaacgggttc cttcccctgc acctggcctg2101 ggccacacct gagcgctgtg gactgtcctg aggagccctg aggacctctc agcatagcct2161 gcctgatccc tgaacccctg gccagctctg aggggaggca cctccaggca ggccaggctg2221 cctcggactc catggctaag accacagacg ggcacacaga ctggagaaaa cccctcccac2281 ggtgcccaaa caccagtcac ctcgtctccc tggtgcctct gtgcacagtg gcttcttttc2341 gttttcgttt tgaagacgtg gactcctctt ggtgggtgtg gccagcacac caagtggctg2401 ggtgccctct caggtgggtt agagatggag tttgctgttg aggtggtgta gatggtgacc2461 tgggtatccc ctgcctcctg ccaccccttc ctccccatac tccactctga ttcacctctt2521 cctctggttc ctttcatctc tctacctcca ccctgcattt tcctcttgtc ctggcccttc2581 agtctgctcc accaaggggc tcttgaaccc cttattaagg ccccagatga ccccagtcac2641 tcctctctag ggcagaagac tagaggccag ggcagcaagg gacctgctca tcatattcca2701 acccagccac gactgccatg taaggttgtg cagggtgtgt actgcacaag gacattgtat2761 gcagggagca ctgttcacat catagataaa gctgatttgt atatttatta tgacaatttc2821 tggcagatgt aggtaaagag gaaaaggatc cttttcctaa ttcacacaaa gactccttgt2881 ggactggctg tgcccctgat gcagcctgtg gctggagtgg ccaaatagga gggagactgt2941 ggtaggggca gggaggcaac actgctgtcc acatgacctc catttcccaa agtcctctgc3001 tccagcaact gcccttccag gtgggtgtgg gacacctggg agaaggtctc caagggaggg3061 tgcagccctc ttgcccgcac ccctccctgc ttgcacactt ccccatcttt gatccttctg3121 agctccacct ctggtggctc ctcctaggaa accagctcgt gggctgggaa tgggggagag3181 aagggaaaag atccccaaga ccccctgggg tgggatctga gctcccacct cccttcccac3241 ctactgcact ttcccccttc ccgccttcca aaacctgctt ccttcagttt gtaaagtcgg3301 tgattatatt tttgggggct ttccttttat tttttaaatg taaaatttat ttatattccg3361 tatttaaagt tgt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142
<210>17<211>2653<212>DNA<213>人類(Homo sapiens)<400>171 atggccctgt ccactgagca tcctcccgcc acacagaaac ccgcccagcc ggggccaccg61 accccacccc ctgcctggaa acttaaggag gccggagctg tggggagctc agagctgaga121 tcctacagga gtccagggct ggagagaaaa cctctgcgag gaaagggaag gagcaagccg181 tgaatttaag ggacgctgtg aagcaatcat ggatgcaatg aagagagggc tctgctgtgt241 gctgctgctg tgtggagcag tcttcgtttc gcccagccag gaaatccatg cccgattcag301 aagaggagcc agatcttacc aagtgatctg cagagatgaa aaaacgcaga tgatatacca361 gcaacatcag tcatggctgc gccctgtgct cagaagcaac cgggtggaat attgctggtg421 caacagtggc agggcacagt gccactcagt gcctgtcaaa agttgcagcg agccaaggtg481 tttcaacggg ggcacctgcc agcaggccct gtacttctca gatttcgtgt gccagtgccc541 cgaaggattt gctgggaagt gctgtgaaat agataccagg gccacgtgct acgaggacca601 gggcatcagc tacaggggca cgtggagcac agcggagagt ggcgccgagt gcaccaactg661 gaacagcagc gcgttggccc agaagcccta cagcgggcgg aggccagacg ccatcaggct721 gggcctgggg aaccacaact actgcagaaa cccagatcga gactcaaagc cctggtgcta781 cgtctttaag gcggggaagt acagctcaga gttctgcagc acccctgcct gctctgaggg841 aaacagtgac tgctactttg ggaatgggtc agcctaccgt ggcacgcaca gcctcaccga901 gtcgggtgcc tcctgcctcc cgtggaattc catgatcctg ataggcaagg tttacacagc961 acagaacccc agtgcccagg cactgggcct gggcaaacat aattactgcc ggaatcctga1021 tggggatgcc aagccctggt gccacgtgct gaagaaccgc aggctgacgt gggagtactg1081 tgatgtgccc tcctgctcca cctgcggcct gagacagtac agccagcctc agtttcgcat1141 caaaggaggg ctcttcgccg acatcgcctc ccacccctgg caggctgcca tctttgccaa1201 gcacaggagg tcgcccggag agcggttcct gtgcgggggc atactcatca gctcctgctg1261 gattctctct gccgcccact gcttccagga gaggtttccg ccccaccacc tgacggtgat1321 cttgggcaga acataccggg tggtccctgg cgaggaggag cagaaatttg aagtcgaaaa1381 atacattgtc cataaggaat tcgatgatga cacttacgac aatgacattg cgctgctgca1441 gctgaaatcg gattcgtccc gctgtgccca ggagagcagc gtggtccgca ctgtgtgcct1501 tcccccggcg gacctgcagc tgccggactg gacggagtgt gagctctccg gctacggcaa1561 gcatgaggcc ttgtctcctt tctattcgga gcggctgaag gaggctcatg tcagactgta1621 cccatccagc cgctgcacat cacaacattt acttaacaga acagtcaccg acaacatgct1681 gtgtgctgga gacactcgga gcggcgggcc ccaggcaaac ttgcacgacg cctgccaggg1741 cgattcggga ggccccctgg tgtgtctgaa cgatggccgc atgactttgg tgggcatcat1801 cagctggggc ctgggctgtg gacagaagga tgtcccgggt gtgtacacca aggttaccaa1861 ctacctagac tggattcgtg acaacatgcg accgtgacca ggaacacccg actcctcaaa1921 agcaaatgag atcccgcctc ttcttcttca gaagacactg caaaggcgca gtgcttctct1981 acagacttct ccagacccac cacaccgcag aagcgggacg agaccctaca ggagagggaa2041 gagtgcattt tcccagatac ttcccatttt ggaagttttc aggacttggt ctgatttcag2101 gatactctgt cagatgggaa gacatgaatg cacactagcc tctccaggaa tgcctcctcc2161 ctgggcagaa agtggccatg ccaccctgtt ttcagctaaa gcccaacctc ctgacctgtc2221 accgtgagca gctttggaaa caggaccaca aaaatgaaag catgtctcaa tagtaaaaga2281 taacaagatc tttcaggaaa gacggattgc attagaaata gacagtatat ttatagtcac2341 aagagcccag cagggcctca aagttggggc aggctggctg gcccgtcatg ttcctcaaaa2401 gcacccttga cgtcaagtct ccttcccctt tccccactcc ctggctctca gaaggtattc2461 cttttgtgta cagtgtgtaa agtgtaaatc ctttttcttt ataaacttta gagtagcatg2521 agagaattgt atcatttgaa caactaggct tcagcatatt tatagcaatc catgttagtt
2581 tttactttct gttgccacaa ccctgtttta tactgtactt aataaattca gatatatttt2641 tcacagtttt tcc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>18<211>1254<212>DNA<213>人類(Homo sapiens)<400>181 atgaagacgg agcggccccg gcccaacacc ttcatcatcc gctgcctgca gtggaccact61 gtcatcgaac gcaccttcca tgtggagact cctgaggagc gggaggagtg gacaaccgcc121 atccagactg tggccgacgg cctcaagaag caggaggagg aggagatgga cttccggtcg181 ggctcaccca gcgacaactc aggggccgaa gagatggagg tgtccctggc caagcccaag241 caccgcgtga ccatgaacga gtttgagtac ctgaagctgc tgggcaaggg cactttcggc301 aaggtgatcc tggtgaagga gaaggccaca gcgtactacg ccatgaagat cctcaagaag361 gaagtcatcg tggccaagga cgaggtggcc cacacactca ccgagaaccg cgtccagcag421 aactccaggc accccttcct cactcgcctg aagtactctt tccagaccca cgaccgcctc481 tgctttgtca tggagtacgc caacgggggc gagctgttct tccacctgtc ccgggagcgt541 gtgttcgccg aggaccgggc ccgcttctat ggcgctgaga ttgtgtcagc cctggactac601 ctgcactcgg agaagaacgt ggtgtaccgg gacctcaagc tggagaacct catgctggac661 aaggacgggc acattaagat cacagacttc gggctgtgca aggaggggat caaggacggt721 gccaccatga agaccttttg cggcacacct gagtacctgg cccccgaggt gctggaggac781 aatgactacg gccgtgcagt ggactggtgg gggctgggcg tggtcatgta cgagatgatg841 tgcggtcgcc tgcccttcta caaccaggac catgagaagc tttttgagct catcctcatg901 gaggagatcc gcttcccgcg cacgcttggt cccgaggcca agtccttgct ttcagggctg961 ctcaagaagg accccaagca gaggcttggc gggggctccg aggacgccaa ggagatcatg1021 cagcatcgct tctttaccgg tatcgtgtgg cagcacgtgt acgagaagaa gctcagccca1081 cccttcaagc cccaggtcac gtcggagact gacaccaggt attttgatga ggagttcacg1141 gcccagatga tcaccatcac accacctgac caagatgaca gcatggagtg tgtggacagc1201 gagcgcaggc cccacttccc ccagttctcc tactcgccca gcgcgacggc ctga<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>19<211>1828<212>DNA<213>人類(Homo sapiens)<400>191 acttctccct agagcagggg tgtttgccag cagcctgcac tctcagaaat cagacttgag61 tggccggaac ccttgagacc agaggcttac catgctgctc cctaggaggg ccaggaactg121 ctgacgtgac cactggacag ttattcgtgt ctcttacaat taccaaacag aatggacaag181 cttaataaaa taaccgtccc cgccagtcag aagttgaggc agcttcaaaa gatggtccat241 gatattaaaa acaatgaagg tggaataatg aataaaatca aaaagctaaa agtcaaagca301 cctccaagtg ttcctcgaag ggactacgct tcagagagcc ctgctgacga agaggagcag361 tggtccgatg actttgacag cgactatgaa aatccagatg agcactcgga ctcagagatg
421 tacgtgatgc ccgccgagga gaacgctgat gacagctacg agccgcctcc agtagagcag481 gaaaccaggc cggttcaccc agccctgccc ttcgccagag gcgagtatat agacaatcga541 tcaagccaga ggcattcccc acccttcagc aagacacttc ccagtaagcc cagctggcct601 tcagagaaag caaggctcac ctccaccctg ccggccctga ctgctttgca gaaacctcaa661 gtcccaccca aacccaaagg cctccttgag gatgaggctg attatgtggt ccccgtggaa721 gataatgatg aaaactatat tcatcccaca gaaagcagtt cacctccacc tgaaaaagct781 cccatggtga atagatcaac caagccaaat tcctcaacgc ccgcctctcc tccaggaaca841 gcttcaggtc gaaacagtgg ggcctgggaa accaagtcac ctccaccagc tgcaccatcc901 ccgttgccac gggccgggaa aaaaccaacg acaccactga agacaactcc agttgcctct961 caacagaatg cttcaagtgt ttgtgaagaa aaacctatac ctgctgaacg ccaccgaggg1021 tcaagtcaca gacaagaagc tgtgcagtca ccagtgtttc ctcctgccca gaaacaaatc1081 caccaaaaac ccatacctct gccaagattt acagaagggg gaaacccaac tgtggatggg1141 cccctaccca gcttttcatc taattccact atttcagaac aggaagctgg cgttctctgc1201 aagccatggt atgctggagc ctgtgatcga aagtctgctg aagaggcatt gcacagatca1261 aacaaggatg gatcatttct tattcggaaa agctctggcc atgattccaa acaaccatat1321 acactagttg tattctttaa taagcgagta tataatattc ctgtgcgatt tattgaagca1381 acaaaacaat atgccttggg cagaaagaaa aatggtgaag agtactttgg aagtgttgct1441 gaaatcatca ggaatcatca acatagtcct ttggttctta ttgacagtca gaataacaca1501 aaagattcca ccagactgaa gtatgcagtt aaagtttcat aaagggggaa aaaaaagatc1561 aataccattg cttcagacac tttcccaaag tttctccttt tgagaaaaag tcccaaaact1621 tcatattttg gattatgaat catccagtaa taaaatggaa gatggagtca gctattgaag1681 tggtcatcca tttcttttta agaagctcat gtggacttgt tctattgcct gacctgatga1741 actgttaata tctggtgagg ttgagttatc atgctactaa tattttccaa ataaatattt1801 ttatttttaa aaataaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>20<211>1936<212>DNA<213>人類(Homo sapiens)<400>201 ccggagcctc ctggaccagg agaactgtaa cgcgagcccc gagccatggg cgaaaggcgg61 ggccgagacg ggttgggggc gccgacggtt tcccggccct ggctgcagct tggaggagaa121 gctgagcctg tgcttccgcc cctcggatcc gggcgccgag cccgaggacg gccgtgcggc181 catcacggag ctcaactcct gcagggggac gagatttgga atgccctgac agataattat241 gggaatgtga tgcctgtaga ctggaagtca tcgcatacta ggaccttgca cttgcttact301 ctgaacctct cagaaaaagg ggtaagtgac agtttgctct ttgatacatc agatgatgaa361 gagctgagag aacagctgga tatgcactca atcatcgtct cctgtgttaa tgatgaaccc421 ctcttcacgg cagaccaggt tattgaagaa attgaagaaa tgatgcagga atcaccggac481 ccagaagatg atgaaacccc tacacagtca gatcggcttt caatgctttc ccaggaaatt541 caaactctca agaggtctag taccggcagt tatgaagaga gagtgaaaag gctctcagtg601 tctgagttaa atgaaatcct ggaagaaatt gagactgcca ttaaggagta ctctgaggag661 ctggtgcagc agttggcttt acgagatgaa ctggagtttg aaaaggaagt gaaaaacagc721 tttatttctg ttcttattga agtgcaaaac aaacagaaag agcacaaaga aacagcaaaa781 aagaaaaaga aactaaaaaa tggcagctct cagaatggga agaatgagag aagtcatatg841 cccggcacat atttgactac agtcattcct tatgagaaaa aaaacggacc accgtctgtt
901 gaagatcttc aaatattaac aaaaattctt cgtgccatga aggaggacag tgaaaaagtt961 ccgagcttgt taactgatta tattctgaaa gttctgtgtc ctacatagag cagcaacttt1021 atctgcggtg ggctccaagc tagatttccg acagcattat tctgagagct ggctaccatt1081 acccttcttg ctattggaaa ctcagcacat ttgaacttgg gtttgattca gtattaacag1141 atcttgacta cactaattct ttatattata gaaccaacgg aaatatgggc actattttga1201 attctagaga tggtttttgt taaatctact aataaactgt tctcttagta gattaagaga1261 gagtaatatt aattgtgcat gtgcagttgt atttctcatt aactgacagt atgcccattt1321 gtttttatgg ctttcttatc taaactgcac tgatgaacta gattaaagcc ttgggagatt1381 tatactataa attcagtgat ggcaagaacc aacactgttt ttttgtgaga attgtcagtg1441 taactattac ctaccagtat tgttcagaga gattgaaaca gaataaacgg gctgttcttg1501 aagaagcaaa accagaatat gcattacttt ggtttaatac ttagtgctaa cattgaaact1561 gttggtggtg atggattttg tagcttgctg cttgtttcac cactggtcaa attttaacca1621 ttaaattgcc attcactttt agaatcttgt atttaagtaa gttttgattt tcaaatgttc1681 tgcttcatgt gtctgtgaag aattgtactt ttttaaaagt gtgtgtcctc tgaggtgctt1741 gagaaagtgt acactgcaga actgcccatt ctcattactg tgtcctattt tattcatgcc1801 tgtgtgtttt tcttaagtat gaattctaga tacagctact tatggattca tcaatatcat1861 gagcactttt gctggttcca gtcaaatcaa tggcatttaa taaatttttt aagaagtaaa1921 aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>21<211>2443<212>DNA<213>人類(Homo sapiens)<400>211 cccccccccg ccgctgccgc ctctgcctgg gtcccttcgg ccgtacctct gcgtgggggc61 tgcctccccg gctcccggtg cagacaccat gtacggattt gtgaatcacg ccctggagtt121 gctggtgatc cgcaattacg gccccgaggt gtgggaagac atcaaaaaag aggcacagtt181 agatgaagaa ggacagtttc ttgtcagaat aatatatgat gactccaaaa cttatgattt241 ggttgctgct gcaagcaaag tcctcaatct caatgctgga gaaatcctcc aaatgtttgg301 gaagatgttt ttcgtctttt gccaagaatc tggttatgat acaatcttgc gtgtcctggg361 ctctaatgtc agagaatttc tacagaacct tgatgctctg cacgaccacc ttgctaccat421 ctacccagga atgcgtgcac cttcctttag gtgcactgat gcagaaaagg gcaaaggact481 cattttgcac tactactcag agagagaagg acttcaggat attgtcattg gaatcatcaa541 aacagtggca caacaaatcc atggcactga aatagacatg aaggttattc agcaaagaaa601 tgaagaatgt gatcatactc aatttttaat tgaagaaaaa gagtcaaaag aagaggattt661 ttatgaagat cttgacagat ttgaagaaaa tggtacccag gaatcacgca tcagcccata721 tacattctgc aaagcttttc cttttcatat aatatttgac cgggacctag tggtcactca781 gtgtggcaat gctatataca gagttctccc ccagctccag cctgggaatt gcagccttct841 gtctgtcttc tcgctggttc gtcctcatat tgatattagt ttccatggga tcctttctca901 catcaatact gtttttgtat tgagaagcaa ggaaggattg ttggatgtgg agaaattaga961 atgtgaggat gaactgactg ggactgagat cagctgctta cgtctcaagg gtcaaatgat1021 ctacttacct gaagcagata gcatactttt tctatgttca ccaagtgtca tgaacctgga1081 cgatttgaca aggagagggc tgtatctaag tgacatccct ctgcatgatg ccacgcgcga1141 tcttgttctt ttgggagaac aatttagaga ggaatacaaa ctcacccaag aactggaaat1201 cctcactgac aggctacagc tcacgttaag agccctggaa gatgaaaaga aaaagacaga
1261 cacattgctg tattctgtcc ttcctccgtc tgttgccaat gagctgcggc acaagcgtcc1321 agtgcctgcc aaaagatatg acaatgtgac catcctcttt agtggcattg tgggcttcaa1381 tgctttctgt agcaagcatg catctggaga aggagccatg aagatcgtca acctcctcaa1441 cgacctctac accagatttg acacactgac tgattcccgg aaaaacccat ttgtttataa1501 ggtggagact gttggtgaca agtatatgac agtgagtggt ttaccagagc catgcattca1561 ccatgcacga tccatctgcc acctggcctt ggacatgatg gaaattgctg gccaggttca1621 agtagatggt gaatctgttc agataacaat agggatacac actggagagg tagttacagg1681 tgtcatagga cagcggatgc ctcgatactg tctttttggg aatactgtca acctcacaaa1741 ccgaacagaa accacaggag aaaagggaaa aataaatgtg tctgaatata catacagatg1801 tcttatgtct ccagaaaatt cagatccaca attccacttg gagcacagag gcccagtgtc1861 catgaagggc aaaaaagaac caatgcaagt ttggtttcta tccagaaaaa atacaggaac1921 agaggaaaca aagcaggatg atgactgaat cttggattat ggggtgaaga ggagtacaga1981 ctaggttcca gttttctcct aacacgtgcc aagcccagga gcagttcttc cctatggata2041 cagattttct tttgtccttg tccattaccc caagactttc ttctagatat atctctcact2101 atccgttatt caaccttagc tctgctttct attacttttt aggctttagt atattatcta2161 aagtttggct tttgatgtgg atgatgtgag cttcatgtgt cttaaaatct actacaagca2221 ttacctaaca tggtgatctg caagtagtag gcacccaata aatatttgtt gaatttagtt2281 aaatgaaact gaacagtgtt tggccatgtg tatatttata tcatgtttac caaatctgtt2341 tagtgttcca catatatgta tatgtatatt ttaatgacta taatgtaata aagtttatat2401 catgttggtg tatatcatta tagaaatcat tttctaaagg agt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>22<211>1424<212>DNA<213>人類(Homo sapiens)<400>221 gaaggactgg ggaagactgg atgagaaggg tagaagaggg tgggtgtggg atggggaggg61 gagagtggaa aggccctggg cagaccctgg cagaaggggc acggggcagg gtgtgagttc121 cccactagca gggccaggtg agctatggtg ctgcacctac tgctcttctt gctgctgacc181 ccacagggtg ggcacagctg ccaggggctg gagctggccc gggaacttgt tctggccaag241 gtgagggccc tgttcttgga tgccttgggg ccccccgcgg tgaccaggga aggtggggac301 cctggagtca ggcggctgcc ccgaagacat gccctggggg gcttcacaca caggggctct361 gagcccgagg aagaggagga tgtctcccaa gccatccttt tcccagccac agatgccagc421 tgtgaggaca agtcagctgc cagagggctg gcccaggagg ctgaggaggg cctcttcaga481 tacatgttcc ggccatccca gcatacacgc agccgccagg tgacttcagc ccagctgtgg541 ttccacaccg ggctggacag gcagggcaca gcagcctcca atagctctga gcccctgcta601 ggcctgctgg cactgtcacc gggaggaccc gtggctgtgc ccatgtcttt gggccatgct661 ccccctcact gggccgtgct gcacctggcc acctctgctc tctctctgct gacccacccc721 gtcctggtgc tgctgctgcg ctgtcccctc tgtacctgct cagcccggcc tgaggccacg781 cccttcctgg tggcccacac tcggaccaga ccacccagtg gaggggagag agcccgacgc841 tcaactcccc tgatgtcctg gccttggtct ccctctgctc tgcgcctgct gcagaggcct901 ccggaggaac cggctgccca tgccaactgc cacagagtag cactgaacat ctccttccag961 gagctgggct gggaacggtg gatcgtgtac cctcccagtt tcatcttcca ctactgtcat1021 ggtggttgtg ggctgcacat cccaccaaac ctgtcccttc cagtccctgg ggctccccct1081 accccagccc agccctactc cttgctgcca ggggcccagc cctgctgtgc tgctctccca
1141 gggaccatga ggcccctaca tgtccgcacc acctcggatg gaggttactc tttcaagtat1201 gagacagtgc ccaaccttct cacgcagcac tgtgcttgta tctaagggtg gggggtcttc1261 cttcttaatc ccatggctgg tggccacgcc cccaccatca tcagctggga ggaaaggcag1321 agttgggaaa tagatggctc ccactcctcc ctcctttcac ttctctgcct atgggctacc1381 ctccccaccc cacttctatc tcaataaaga acacagtgca tatg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>23<211>3334<212>DNA<213>人類(Homo sapiens)<400>231 attcctgcct gggaggttgt ggaagaagga agatggccag agctttgtgt ccactgcaag61 ccctctggct tctggagtgg gtgctgctgc tcttgggacc ttgtgctgcc cctccagcct121 gggccttgaa cctggaccca gtgcagctca ccttctatgc aggccccaat ggcagccagt181 ttggattttc actggacttc cacaaggaca gccatgggag agtggccatc gtggtgggcg241 ccccgcggac cctgggcccc agccaggagg agacgggcgg cgtgttcctg tgcccctgga301 gggccgaggg cggccagtgc ccctcgctgc tctttgacct ccgtgatgag acccgaaatg361 taggctccca aactttacaa accttcaagg cccgccaagg actgggggcg tcggtcgtca421 gctggagcga cgtcattgtg gcctgcgccc cctggcagca ctggaacgtc ctagaaaaga481 ctgaggaggc tgagaagacg cccgtaggta gctgcttttt ggctcagcca gagagcggcc541 gccgcgccga gtactccccc tgtcgcggga acaccctgag ccgcatttac gtggaaaatg601 attttagctg ggacaagcgt tactgtgaag cgggcttcag ctccgtggtc actcaggccg661 gagagctggt gcttggggct cctggcggct attatttctt aggtctcctg gcccaggctc721 cagttgcgga tattttctcg agttaccgcc caggcatcct tttgtggcac gtgtcctccc781 agagcctctc ctttgactcc agcaacccag agtacttcga cggctactgg gggtactcgg841 tggccgtggg cgagttcgac ggggatctca acactacaga atatgtcgtc ggtgccccca901 cttggagctg gaccctggga gcggtggaaa ttttggattc ctactaccag aggctgcatc961 ggctgcgcgc agagcagatg gcgtcgtatt ttgggcattc agtggctgtc actgacgtca1021 acggggatgg gaggcatgat ctgctggtgg gcgctccact gtatatggag agccgggcag1081 accgaaaact ggccgaagtg gggcgtgtgt atttgttcct gcagccgcga ggcccccacg1141 cgctgggtgc ccccagcctc ctgctgactg gcacacagct ctatgggcga ttcggctctg1201 ccatcgcacc cctgggcgac ctcgaccggg atggctacaa tgacattgca gtggctgccc1261 cctacggggg tcccagtggc cggggccaag tgctggtgtt cctgggtcag agtgaggggc1321 tgaggtcacg tccctcccag gtcctggaca gccccttccc cacaggctct gcctttggct1381 tctcccttcg aggtgccgta gacatcgatg acaacggata cccagacctg atcgtgggag1441 cttacggggc caaccaggtg gctgtgtaca gagctcagcc agtggtgaag gcctctgtcc1501 agctactggt gcaagattca ctgaatcctg ctgtgaagag ctgtgtccta cctcagacca1561 agacacccgt gagctgcttc aacatccaga tgtgtgttgg agccactggg cacaacattc1621 ctcagaagct atccctaaat gccgagctgc agctggaccg gcagaagccc cgccagggcc1681 ggcgggtgct gctgctgggc tctcaacagg caggcaccac cctgaacctg gatctgggcg1741 gaaagcacag ccccatctgc cacaccacca tggccttcct tcgagatgag gcagacttcc1801 gggacaagct gagccccatt gtgctcagcc tcaatgtgtc cctaccgccc acggaggctg1861 gaatggcccc tgctgtcgtg ctgcatggag acacccatgt gcaggagcag acacgaatcg1921 tcctggactc tggggaagat gacgtatgtg tgccccagct tcagctcact gccagcgtga1981 cgggctcccc gctcctagtt ggggcagata atgtcctgga gctgcagatg gacgcagcca
2041 acgagggcga gggggcctat gaagcagagc tggccgtgca cctgccccag ggcgcccact2101 acatgcgggc cctaagcaat gtcgagggct ttgagagact catctgtaat cagaagaagg2161 agaatgagac cagggtggtg ctgtgtgagc tgggcaaccc catgaagaag aacgcccaga2221 taggaatcgc gatgttggtg agcgtgggga atctggaaga ggctggggag tctgtgtcct2281 tccagctgca gatacggagc aagaacagcc agaatccaaa cagcaagatt gtgctgctgg2341 acgtgccggt ccgggcagag gcccaagtgg agctgcgagg gaactccttt ccagcctccc2401 tggtggtggc agcagaagaa ggtgagaggg agcagaacag cttggacagc tggggaccca2461 aagtggagca cacctatgag ctccacaaca atggccctgg gactgtgaat ggtcttcacc2521 tcagcatcca ccttccggga cagtcccagc cctccgacct gctctacatc ctggatatac2581 agccccaggg gggccttcag tgcttcccac agcctcctgt caaccctctc aaggtggact2641 gggggctgcc catccccagc ccctccccca ttcacccggc ccatcacaag cgggatcgca2701 gacagatctt cctgccagag cccgagcagc cctcgaggct tcaggatcca gttctcgtaa2761 gctgcgactc ggcgccctgt actgtggtgc agtgtgacct gcaggagatg gcgcgcgggc2821 agcgggccat ggtcacggtg ctggccttcc tgtggctgcc cagcctctac cagaggcctc2881 tggatcagtt tgtgctgcag tcgcacgcat ggttcaacgt gtcctccctc ccctatgcgg2941 tgcccccgct cagcctgccc cgaggggaag ctcaggtgtg gacacagctg ctccgggcct3001 tggaggagag ggccattcca atctggtggg tgctggtggg tgtgctgggt ggcctgctgc3061 tgctcaccat cctggtcctg gccatgtgga aggtcggctt cttcaagcgg aaccggccac3121 ccctggaaga agatgatgaa gagggggagt gatggtgcag cctacactat tctagcagga3181 gggttgggcg tgctacctgc accgcccctt ctccaacaag ttgcctccaa gctttgggtt3241 ggagctgttc cattgggtcc tcttggtgtc gtttccctcc caacagagct gggctacccc3301 ccctcctgct gcctaataaa gagactgagc cctg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>24<211>11433<212>DNA<213>人類(Homo sapiens)<400>241 aggctgcttc gttgcacacc cgagaaagtt tcagccaaac ttcgggcggc ggctgaggcg61 gcggccgagg agcggcggac tcggggcgcg gggagtcgag gcatttgcgc ctgggcttcg121 gagcgtagcg ccagggcctg agcctttgaa gcaggaggag gggaggagag agtggggctc181 ctctatcggg accccctccc catgtggatc tgcccaggcg gcggcggcgg cggcggagga241 ggaggcgacc gagaagatgc ccgccctgcg ccccgctctg ctgtgggcgc tgctggcgct301 ctggctgtgc tgcgcggccc ccgcgcatgc attgcagtgt cgagatggct atgaaccctg361 tgtaaatgaa ggaatgtgtg ttacctacca caatggcaca ggatactgca aatgtccaga421 aggcttcttg ggggaatatt gtcaacatcg agacccctgt gagaagaacc gctgccagaa481 tggtgggact tgtgtggccc aggccatgct ggggaaagcc acgtgccgat gtgcctcagg541 gtttacagga gaggactgcc agtactcaac atctcatcca tgctttgtgt ctcgaccctg601 cctgaatggc ggcacatgcc atatgctcag ccgggatacc tatgagtgca cctgtcaagt661 cgggtttaca ggtaaggagt gccaatggac ggatgcctgc ctgtctcatc cctgtgcaaa721 tggaagtacc tgtaccactg tggccaacca gttctcctgc aaatgcctca caggcttcac781 agggcagaaa tgtgagactg atgtcaatga gtgtgacatt ccaggacact gccagcatgg841 tggcacctgc ctcaacctgc ctggttccta ccagtgccag tgccctcagg gcttcacagg901 ccagtactgt gacagcctgt atgtgccctg tgcaccctca ccttgtgtca atggaggcac961 ctgtcggcag actggtgact tcacttttga gtgcaactgc cttccaggtt ttgaagggag
1021 cacctgtgag aggaatattg atgactgccc taaccacagg tgtcagaatg gaggggtttg1081 tgtggatggg gtcaacactt acaactgccg ctgtccccca caatggacag gacagttctg1141 cacagaggat gtggatgaat gcctgctgca gcccaatgcc tgtcaaaatg ggggcacctg1201 tgccaaccgc aatggaggct atggctgtgt atgtgtcaac ggctggagtg gagatgactg1261 cagtgagaac attgatgatt gtgccttcgc ctcctgtact ccaggctcca cctgcatcga1321 ccgtgtggcc tccttctctt gcatgtgccc agaggggaag gcaggtctcc tgtgtcatct1381 ggatgatgca tgcatcagca atccttgcca caagggggca ctgtgtgaca ccaaccccct1441 aaatgggcaa tatatttgca cctgcccaca aggctacaaa ggggctgact gcacagaaga1501 tgtggatgaa tgtgccatgg ccaatagcaa tccttgtgag catgcaggaa aatgtgtgaa1561 cacggatggc gccttccact gtgagtgtct gaagggttat gcaggacctc gttgtgagat1621 ggacatcaat gagtgccatt cagacccctg ccagaatgat gctacctgtc tggataagat1681 tggaggcttc acatgtctgt gcatgccagg tttcaaaggt gtgcattgtg aattagaaat1741 aaatgaatgt cagagcaacc cttgtgtgaa caatgggcag tgtgtggata aagtcaatcg1801 tttccagtgc ctgtgtcctc ctggtttcac tgggccagtt tgccagattg atattgatga1861 ctgttccagt actccgtgtc tgaatggggc aaagtgtatc gatcacccga atggctatga1921 atgccagtgt gccacaggtt tcactggtgt gttgtgtgag gagaacattg acaactgtga1981 ccccgatcct tgccaccatg gtcagtgtca ggatggtatt gattcctaca cctgcatctg2041 caatcccggg tacatgggcg ccatctgcag tgaccagatt gatgaatgtt acagcagccc2101 ttgcctgaac gatggtcgct gcattgacct ggtcaatggc taccagtgca actgccagcc2161 aggcacgtca ggggttaatt gtgaaattaa ttttgatgac tgtgcaagta acccttgtat2221 ccatggaatc tgtatggatg gcattaatcg ctacagttgt gtctgctcac caggattcac2281 agggcagaga tgtaacattg acattgatga gtgtgcctcc aatccctgtc gcaagggtgc2341 aacatgtatc aacggtgtga atggtttccg ctgtatatgc cccgagggac cccatcaccc2401 cagctgctac tcacaggtga acgaatgcct gagcaatccc tgcatccatg gaaactgtac2461 tggaggtctc agtggatata agtgtctctg tgatgcaggc tgggttggca tcaactgtga2521 agtggacaaa aatgaatgcc tttcgaatcc atgccagaat ggaggaactt gtgacaatct2581 ggtgaatgga tacaggtgta cttgcaagaa gggctttaaa ggctataact gccaggtgaa2641 tattgatgaa tgtgcctcaa atccatgcct gaaccaagga acctgctttg atgacataag2701 tggctacact tgccactgtg tgctgccata cacaggcaag aattgtcaga cagtattggc2761 tccctgttcc ccaaaccctt gtgagaatgc tgctgtttgc aaagagtcac caaattttga2821 gagttatact tgcttgtgtg ctcctggctg gcaaggtcag cggtgtacca ttgacattga2881 cgagtgtatc tccaagccct gcatgaacca tggtctctgc cataacaccc agggcagcta2941 catgtgtgaa tgtccaccag gcttcagtgg tatggactgt gaggaggaca ttgatgactg3001 ccttgccaat ccttgccaga atggaggttc ctgtatggat ggagtgaata ctttctcctg3061 cctctgcctt ccgggtttca ctggggataa gtgccagaca gacatgaatg agtgtctgag3121 tgaaccctgt aagaatggag ggacctgctc tgactacgtc aacagttaca cttgcaagtg3181 ccaggcagga tttgatggag tccattgtga gaacaacatc aatgagtgca ctgagagctc3241 ctgtttcaat ggtggcacat gtgttgatgg gattaactcc ttctcttgct tgtgccctgt3301 gggtttcact ggatccttct gcctccatga gatcaatgaa tgcagctctc atccatgcct3361 gaatgaggga acgtgtgttg atggcctggg tacctaccgc tgcagctgcc ccctgggcta3421 cactgggaaa aactgtcaga ccctggtgaa tctctgcagt cggtctccat gtaaaaacaa3481 aggtacttgc gttcagaaaa aagcagagtc ccagtgccta tgtccatctg gatgggctgg3541 tgcctattgt gacgtgccca atgtctcttg tgacatagca gcctccagga gaggtgtgct3601 tgttgaacac ttgtgccagc actcaggtgt ctgcatcaat gctggcaaca cgcattactg3661 tcagtgcccc ctgggctata ctgggagcta ctgtgaggag caactcgatg agtgtgcgtc3721 caacccctgc cagcacgggg caacatgcag tgacttcatt ggtggataca gatgcgagtg3781 tgtcccaggc tatcagggtg tcaactgtga gtatgaagtg gatgagtgcc agaatcagcc3841 ctgccagaat ggaggcacct gtattgacct tgtgaaccat ttcaagtgct cttgcccacc
3901 aggcactcgg ggcctactct gtgaagagaa cattgatgac tgtgcccggg gtccccattg3961 ccttaatggt ggtcagtgca tggataggat tggaggctac agttgtcgct gcttgcctgg4021 ctttgctggg gagcgttgtg agggagacat caacgagtgc ctctccaacc cctgcagctc4081 tgagggcagc ctggactgta tacagctcac caatgactac ctgtgtgttt gccgtagtgc4141 ctttactggc cggcactgtg aaaccttcgt cgatgtgtgt ccccagatgc cctgcctgaa420t tggagggact tgtgctgtgg ccagtaacat gcctgatggt ttcatttgcc gttgtccccc4261 gggattttcc ggggcaaggt gccagagcag ctgtggacaa gtgaaatgta ggaaggggga4321 gcagtgtgtg cacaccgcct ctggaccccg ctgcttctgc cccagtcccc gggactgcga4381 gtcaggctgt gccagtagcc cctgccagca cgggggcagc tgccaccctc agcgccagcc4441 tccttattac tcctgccagt gtgccccacc attctcgggt agccgctgtg aactctacac4501 ggcacccccc agcacccctc ctgccacctg tctgagccag tattgtgccg acaaagctcg4561 ggatggcgtc tgtgatgagg cctgcaacag ccatgcctgc cagtgggatg ggggtgactg4621 ttctctcacc atggagaacc cctgggccaa ctgctcctcc ccacttccct gctgggatta4681 tatcgacaac cagtgtgatg agctgtgcaa cacggtcgag tgcctgtttg acaactttga4741 atgccagggg aacagcaaga catgcaagta tgacaaatac tgtgcagacc acttcaaaga4801 caaccactgt gaccaggggt gcaacagtga ggagtgtggt tgggatgggc tggactgtgc4861 tgctgaccaa cctgagaacc tggcagaagg taccctggtt attgtggtat tgatgccacc4921 tgaacaactg ctccaggatg ctcgcagctt cttgcgggca ctgggtaccc tgctccacac4981 caacctgcgc attaagcggg actcccaggg ggaactcatg gtgtacccct attatggtga5041 gaagtcagct gctatgaaga aacagaggat gacacgcaga tcccttcctg gtgaacaaga5101 acaggaggtg gctggctcta aagtctttct ggaaattgac aaccgccagt gtgttcaaga5161 ctcagaccac tgcttcaaga acacggatgc agcagcagct ctcctggcct ctcacgccat5221 acaggggacc ctgtcatacc ctcttgtgtc tgtcgtcagt gaatccctga ctccagaacg5281 cactcagctc ctctatctcc ttgctgttgc tgttgtcatc attctgttta ttattctgct5341 gggggtaatc atggcaaaac gaaagcgtaa gcatggctct ctctggctgc ctgaaggttt5401 cactcttcgc cgagatgcaa gcaatcacaa gcgtcgtgag ccagtgggac aggatgctgt5461 ggggctgaaa aatctctcag tgcaagtctc agaagctaac ctaattggta ctggaacaag5521 tgaacactgg gtcgatgatg aagggcccca gccaaagaaa gtaaaggctg aagatgaggc5581 cttactctca gaagaagatg accccattga tcgacggcca tggacacagc agcaccttga5641 agctgcagac atccgtagga caccatcgct ggctctcacc cctcctcagg cagagcagga5701 ggtggatgtg ttagatgtga atgtccgtgg cccagatggc tgcaccccat tgatgttggc5761 ttctctccga ggaggcagct cagatttgag tgatgaagat gaagatgcag aggactcttc5821 tgctaacatc atcacagact tggtctacca gggtgccagc ctccaggccc agacagaccg5881 gactggtgag atggccctgc accttgcagc ccgctactca cgggctgatg ctgccaagcg5941 tctcctggat gcaggtgcag atgccaatgc ccaggacaac atgggccgct gtccactcca6001 tgctgcagtg gcagctgatg cccaaggtgt cttccagatt ctgattcgca accgagtaac6061 tgatctagat gccaggatga atgatggtac tacacccctg atcctggctg cccgcctggc6121 tgtggaggga atggtggcag aactgatcaa ctgccaagcg gatgtgaatg cagtggatga6181 ccatggaaaa tctgctcttc actgggcagc tgctgtcaat aatgtggagg caactctttt6241 gttgttgaaa aatggggcca accgagacat gcaggacaac aaggaagaga cacctctgtt6301 tcttgctgcc cgggagggga gctatgaagc agccaagatc ctgttagacc attttgccaa6361 tcgagacatc acagaccata tggatcgtct tccccgggat gtggctcggg atcgcatgca6421 ccatgacatt gtgcgccttc tggatgaata caatgtgacc ccaagccctc caggcaccgt6481 gttgacttct gctctctcac ctgtcatctg tgggcccaac agatctttcc tcagcctgaa6541 gcacacccca atgggcaaga agtctagacg gcccagtgcc aagagtacca tgcctactag6601 cctccctaac cttgccaagg aggcaaagga tgccaagggt agtaggagga agaagtctct6661 gagtgagaag gtccaactgt ctgagagttc agtaacttta tcccctgttg attccctaga6721 atctcctcac acgtatgttt ccgacaccac atcctctcca atgattacat cccctgggat
6781 cttacaggcc tcacccaacc ctatgttggc cactgccgcc cctcctgccc cagtccatgc6841 ccagcatgca ctatcttttt ctaaccttca tgaaatgcag cctttggcac atggggccag6901 cactgtgctt ccctcagtga gccagttgct atcccaccac cacattgtgt ctccaggcag6961 tggcagtgct ggaagcttga gtaggctcca tccagtccca gtcccagcag attggatgaa7021 ccgcatggag gtgaatgaga cccagtacaa tgagatgttt ggtatggtcc tggctccagc7081 tgagggcacc catcctggca tagctcccca gagcaggcca cctgaaggga agcacataac7141 cacccctcgg gagcccttgc cccccattgt gactttccag ctcatcccta aaggcagtat7201 tgcccaacca gcgggggctc cccagcctca gtccacctgc cctccagctg ttgcgggccc7261 cctgcccacc atgtaccaga ttccagaaat ggcccgtttg cccagtgtgg ctttccccac7321 tgccatgatg ccccagcagg acgggcaggt agctcagacc attctcccag cctatcatcc7381 tttcccagcc tctgtgggca agtaccccac acccccttca cagcacagtt atgcttcctc7441 aaatgctgct gagcgaacac ccagtcacag tggtcacctc cagggtgagc atccctacct7501 gacaccatcc ccagagtctc ctgaccagtg gtcaagttca tcaccccact ctgcttctga7561 ctggtcagat gtgaccacca gccctacccc tgggggtgct ggaggaggtc agcggggacc7621 tgggacacac atgtctgagc caccacacaa caacatgcag gtttatgcgt gagagagtcc7681 acctccagtg tagagacata actgactttt gtaaatgctg ctgaggaaca aatgaaggtc7741 atccgggaga gaaatgaaga aatctctgga gccagcttct agaggtagga aagagaagat7801 gttcttattc agataatgca agagaagcaa ttcgtcagtt tcactgggta tctgcaaggc7861 ttattgatta ttctaatcta ataagacaag tttgtggaaa tgcaagatga atacaagcct7921 tgggtccatg tttactctct tctatttgga gaataagatg gatgcttatt gaagcccaga7981 cattcttgca gcttggactg cattttaagc cctgcaggct tctgccatat ccatgagaag8041 attctacact agcgtcctgt tgggaattat gccctggaat tctgcctgaa ttgacctacg8101 catctcctcc tccttggaca ttcttttgtc ttcatttggt gcttttggtt ttgcacctct8161 ccgtgattgt agccctacca gcatgttata gggcaagacc tttgtgcttt tgatcattct8221 ggcccatgaa agcaactttg gtctcctttc ccctcctgtc ttcccggtat cccttggagt8281 ctcacaaggt ttactttggt atggttctca gcacaaacct ttcaagtatg ttgtttcttt8341 ggaaaatgga catactgtat tgtgttctcc tgcatatatc attcctggag agagaagggg8401 agaagaatac ttttcttcaa caaattttgg gggcaggaga tcccttcaag aggctgcacc8461 ttaatttttc ttgtctgtgt gcaggtcttc atataaactt taccaggaag aagggtgtga8521 gtttgttgtt tttctgtgta tgggcctggt cagtgtaaag ttttatcctt gatagtctag8581 ttactatgac cctccccact tttttaaaac cagaaaaagg tttggaatgt tggaatgacc8641 aagagacaag ttaactcgtg caagagccag ttacccaccc acaggtcccc ctacttcctg8701 ccaagcattc cattgactgc ctgtatggaa cacatttgtc ccagatctga gcattctagg8761 cctgtttcac tcactcaccc agcatatgaa actagtctta actgttgagc ctttcctttc8821 atatccacag aagacactgt ctcaaatgtt gtacccttgc catttaggac tgaactttcc8881 ttagcccaag ggacccagtg acagttgtct tccgtttgtc agatgatcag tctctactga8941 ttatcttgct gcttaaaggc ctgctcacca atctttcttt cacaccgtgt ggtccgtgtt9001 actggtatac ccagtatgtt ctcactgaag acatggactt tatatgttca agtgcaggaa9061 ttggaaagtt ggacttgttt tctatgatcc aaaacagccc tataagaagg ttggaaaagg9121 aggaactata tagcagcctt tgctattttc tgctaccatt tcttttcctc tgaagcggcc9181 atgacattcc ctttggcaac taacgtagaa actcaacaga acattttcct ttcctagagt9241 caccttttag atgataatgg acaactatag acttgctcat tgttcagact gattgcccct9301 cacctgaatc cactctctgt attcatgctc ttggcaattt ctttgacttt cttttaaggg9361 cagaagcatt ttagttaatt gtagataaag aatagttttc ttcctcttct ccttgggcca9421 gttaataatt ggtccatggc tacactgcaa cttccgtcca gtgctgtgat gcccatgaca9481 cctgcaaaat aagttctgcc tgggcatttt gtagatatta acaggtgaat tcccgactct9541 tttggtttga atgacagttc tcattccttc tatggctgca agtatgcatc agtgcttccc9601 acttacctga tttgtctgtc ggtggcccca tatggaaacc ctgcgtgtct gttggcataa
9661 tagtttacaa atggtttttt cagtcctatc caaatttatt gaaccaacaa aaataattac9721 ttctgccctg agataagcag attaagtttg ttcattctct gctttattct ctccatgtgg9781 caacattctg tcagcctctt tcatagtgtg caaacatttt atcattctaa atggtgactc9841 tctgcccttg gacccattta ttattcacag atggggagaa cctatctgca tggacctctg9901 tggaccacag cgtacctgcc cctttctgcc ctcctgctcc agccccactt ctgaaagtat9961 cagctactga tccagccact ggatatttta tatcctccct tttccttaag cacaatgtca10021 gaccaaattg cttgtttctt tttcttggac tactttaatt tggatccttt gggtttggag10081 aaagggaatg tgaaagctgt cattacagac aacaggtttc agtgatgagg aggacaacac10141 tgcctttcaa actttttact gatctcttag attttaagaa ctcttgaatt gtgtggtatc10201 taataaaagg gaaggtaaga tggataatca ctttctcatt tgggttctga attggagact10261 cagtttttat gagacacatc ttttatgcca tgtatagatc ctcccctgct atttttggtt10321 tatttttatt gttataaatg ctttctttct ttgactcctc ttctgcctgc ctttggggat10381 aggttttttt gtttgtttat ttgcttcctc tgttttgttt taagcatcat tttcttatgt10441 gaggtgggga agggaaaggt atgagggaaa gagagtctga gaattaaaat attttagtat10501 aagcaattgg ctgtgatgct caaatccatt gcatcctctt attgaatttg ccaatttgta10561 atttttgcat aataaagaac caaaggtgta atgttttgtt gagaggtggt ttagggattt10621 tggccctaac caatacattg aatgtatgat gactatttgg gaggacacat ttatgtaccc10681 agaggccccc actaataagt ggtactatgg ttacttcctt gtgtacattt ctcttaaaag10741 tgatattata tctgtttgta tgagaaaccc agtaaccaat aaaatgaccg catattcctg10801 actaaacgta gtaaggaaaa tgcacacttt gtttttactt ttccgtttca ttctaaaggt10861 agttaagatg aaatttatat gaaagcattt ttatcacaaa ataaaaaagg tttgccaagc10921 tcagtggtgt tgtatttttt attttccaat actgcatcca tggcctggca gtgttacctc10981 atgatgtcat aatttgctga gagagcaaat tttcttttct ttctgaatcc cacaaagcct11041 agcaccaaac ttcttttttt cttcctttaa ttagatcata aataaatgat cctggggaaa11101 aagcatctgt caaataggaa acatcacaaa actgagcact cttctgtgca ctagccatag11161 ctggtgacaa acagatggtt gctcagggac aaggtgcctt ccaatggaaa tgcgaagtag11221 ttgctatagc aagaattggg aactgggata taagtcataa tattaattat gctgttatgt11281 aaatgattgg tttgtaacat tccttaagtg aaatttgtgt agaacttaat atacaggatt11341 ataaaataat attttgtgta taaatttgtt ataagttcac attcatacat ttatttataa11401 agtcagtgag atatttgaac atgaaaaaaa aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>25<211>6762<212>DNA<213>人類(Homo sapiens)<400>251 agacgtgagg cttgcagcag gccgaggagg aagaagaggg gcagtgggag cagaggaggt61 ggctcctgcc ccagtgagag ctctgagggt ccctgcctga agagggacag ggaccggggc121 ttggagaagg ggctgtggaa tgcagccccc ttcactgctg ctgctgctgc tgctgctgct181 gctgctatgt gtctcagtgg tcagacccag agggctgctg tgtgggagtt tcccagaacc241 ctgtgccaat ggaggcacct gcctgagcct gtctctggga caagggacct gccagtgtgc301 ccctggcttc ctgggtgaga cgtgccagtt tcctgacccc tgccagaacg cccagctctg361 ccaaaatgga ggcagctgcc aagccctgct tcccgctccc ctagggctcc ccagctctcc421 ctctccattg agacccagct tcttgtgcac ttgcctccct ggcttcactg gtgagagatg481 ccaggccaag cttgaagacc cttgtcctcc ctccttctgt tccaaaaggg gccgctgcca
541 catccaggcc tcgggccgcc cacagtgctc ctgcatgcct ggatggacag gtgagcagtg601 ccagcttcgg gacttctgtt cagccaaccc atgtgttaat ggaggggtgt gtctggccac661 atacccccag atccagtgcc actgcccacc gggcttcgag ggccatgcct gtgaacgtga721 tgtcaacgag tgcttccagg acccaggacc ctgccccaaa ggcacctcct gccataacac781 cctgggctcc ttccagtgcc tctgccctgt ggggcaggag ggtccacgtt gtgagctgcg841 ggcaggaccc tgccctccta ggggctgttc gaatgggggc acctgccagc tgatgccaga901 gaaagactcc acctttcacc tctgcctctg tcccccaggt ttcataggcc cagactgtga961 ggtgaatcca gacaactgtg tcagccacca gtgtcagaat gggggcactt gccaggatgg1021 gctggacacc tacacctgcc tctgcccaga aacctggaca ggctgggact gctccgaaga1081 tgtggatgag tgtgagaccc agggtccccc tcactgcaga aacgggggca cctgccagaa1141 ctctgctggt agctttcact gcgtgtgtgt gagtggctgg ggcggcacaa gctgtgagga1201 gaacctggat gactgtattg ctgccacctg tgccccggga tccacctgca ttgaccgggt1261 gggctctttc tcctgcctct gcccacctgg acgcacagga ctcctgtgcc acttggaaga1321 catgtgtctg agccagccgt gccatgggga tgcccaatgc agcaccaacc ccctcacagg1381 ctccacactc tgcctgtgtc agcctggcta ttcggggccc acctgccacc aggacctgga1441 cgagtgtctg atggcccagc aaggcccaag tccctgtgaa catggcggtt cctgcctcaa1501 cactcctggc tccttcaact gcctctgtcc acctggctac acaggctccc gttgtgaggc1561 tgatcacaat gagtgcctct cccagccctg ccacccagga agcacctgtc tggacctact1621 tgccaccttc cactgcctct gcccgccagg cttagaaggg cagctctgtg aggtggagac1681 caacgagtgt gcctcagctc cctgcctgaa ccacgcggat tgccatgacc tgctcaacgg1741 cttccagtgc atctgcctgc ctggattctc cggcacccga tgtgaggagg atatcgatga1801 gtgcagaagc tctccctgtg ccaatggtgg gcagtgccag gaccagcctg gagccttcca1861 ctgcaagtgt ctcccaggct ttgaagggcc acgctgtcaa acagaggtgg atgagtgcct1921 gagtgaccca tgtcccgttg gagccagctg ccttgatctt ccaggagcct tcttttgcct1981 ctgcccctct ggtttcacag gccagctctg tgaggttccc ctgtgtgctc ccaacctgtg2041 ccagcccaag cagatatgta aggaccagaa agacaaggcc aactgcctct gtcctgatgg2101 aagccctggc tgtgccccac ctgaggacaa ctgcacctgc caccacgggc actgccagag2161 atcctcatgt gtgtgtgacg tgggttggac ggggccagag tgtgaggcag agctaggggg2221 ctgcatctct gcaccctgtg cccatggggg gacctgctac ccccagccct ctggctacaa2281 ctgcacctgc cctacaggct acacaggacc cacctgtagt gaggagatga cagcttgtca2341 ctcagggcca tgtctcaatg gcggctcctg caaccctagc cctggaggct actactgcac2401 ctgccctcca agccacacag ggccccagtg ccaaaccagc actgactact gtgtgtctgc2461 cccgtgcttc aatgggggta cctgtgtgaa caggcctggc accttctcct gcctctgtgc2521 catgggcttc cagggcccgc gctgtgaggg aaagctccgc cccagctgtg cagacagccc2581 ctgtaggaat agggcaacct gccaggacag ccctcagggt ccccgctgcc tctgccccac2641 tggctacacc ggaggcagct gccagactct gatggactta tgtgcccaga agccctgccc2701 acgcaattcc cactgcctcc agactgggcc ctccttccac tgcttgtgcc tccagggatg2761 gaccgggcct ctctgcaacc ttccactgtc ctcctgccag aaggctgcac tgagccaagg2821 catagacgtc tcttcccttt gccacaatgg aggcctctgt gtcgacagcg gcccctccta2881 tttctgccac tgcccccctg gattccaagg cagcctgtgc caggatcacg tgaacccatg2941 tgagtccagg ccttgccaga acggggccac ctgcatggcc cagcccagtg ggtatctctg3001 ccagtgtgcc ccaggctacg atggacagaa ctgctcaaag gaactcgatg cttgtcagtc3061 ccaaccctgt cacaaccatg gaacctgtac tcccaaacct ggaggattcc actgtgcctg3121 ccctccaggc tttgtggggc tacgctgtga gggagacgtg gacgagtgtc tggaccagcc3181 ctgccacccc acaggcactg cagcctgcca ctctctggcc aatgccttct actgccagtg3241 tctgcctgga cacacaggcc agtggtgtga ggtggagata gacccctgcc acagccaacc3301 ctgctttcat ggagggacct gtgaggccac agcaggatca cccctgggtt tcatctgcca3361 ctgccccaag ggttttgaag gccccacctg cagccacagg gccccttcct gcggcttcca
3421 tcactgccac cacggaggcc tgtgtctgcc ctcccctaag ccaggcttac caccacgctg3481 tgcctgcctc agtggctatg ggggtcctga ctgcctgacc ccaccagcfc ctaaaggctg3541 tggccctccc tccccatgcc tatacaatgg cagctgctca gagaccacgg gcttgggggg3601 cccaggcttt cgatgctcct gccctcacag ctctccaggg ccccggtgtc agaaacccgg3661 agccaagggg tgtgagggca gaagtggaga tggggcctgc gatgctggct gcagtggccc3721 gggaggaaac tgggatggag gggactgctc tctgggagtc ccagacccct ggaagggctg3781 cccctcccac tctcggtgct ggcttctctt ccgggacggg cagtgccacc cacagtgtga3841 ctctgaagag tgtctgtttg atggctacga ctgtgagacc cctccagcct gcactccagc3901 ctatgaccag tactgccatg atcacttcca caacgggcac tgtgagaaag gctgcaacac3961 tgcagagtgt ggctgggatg gaggtgactg caggcctgaa gatggggacc cagagtgggg4021 gccctccctg gccctgctgg tggtactgag ccccccagcc ctagaccagc agctgtttgc4081 cctggcccgg gtgctgtccc tgactctgag ggtaggactc tgggtaagga aggatcgtga4141 tggcagggac atggtgtacc cctatcctgg ggcccgggct gaagaaaagc taggaggaac4201 tcgggacccc acctatcagg agagagcagc ccctcaaacg cagcccctgg gcaaggagac4261 cgactccctc agtgctgggt ttgtggtggt catgggtgtg gatttgtccc gctgtggccc4321 tgaccacccg gcatcccgct gtccctggga ccctgggctt ctactccgct tccttgctgc4381 gatggctgca gtgggagccc tggagcccct gctgcctgga ccactgctgg ctgtccaccc4441 tcatgcaggg accgcacccc ctgccaacca gcttccctgg cctgtgctgt gctccccagt4501 ggccggggtg attctcctgg ccctaggggc tcttctcgtc ctccagctca tccggcgtcg4561 acgccgagag catggagctc tctggctgcc ccctggtttc actcgacggc ctcggactca4621 gtcagctccc caccgacgcc ggcccccact aggcgaggac agcattggtc tcaaggcact4681 gaagccaaag gcagaagttg atgaggatgg agttgtgatg tgctcaggcc ctgaggaggg4741 agaggaggtg ggccaggctg aagaaacagg cccaccctcc acgtgccagc tctggtctct4801 gagtggtggc tgtggggcgc tccctcaggc agccatgcta actcctcccc aggaatctga4861 gatggaagcc cctgacctgg acacccgtgg acctgatggg gtgacacccc tgatgtcagc4921 agtttgctgt ggggaagtac agtccgggac cttccaaggg gcatggttgg gatgtcctga4981 gccctgggaa cctctgctgg atggaggggc ctgtccccag gctcacaccg tgggcactgg5041 ggagaccccc ctgcacctgg ctgcccgatt ctcccggcca accgctgccc gccgcctcct5101 tgaggctgga gccaacccca accagccaga ccgggcaggg cgcacacccc ttcatgctgc5161 tgtggctgct gatgctcggg aggtctgcca gcttctgctc cgtagcagac aaactgcagt5221 ggacgctcgc acagaggacg ggaccacacc cttgatgctg gctgccaggc tggcggtgga5281 agacctggtt gaagaactga ttgcagccca agcagacgtg ggggccagag ataaatgggg5341 gaaaactgcg ctgcactggg ctgctgccgt gaacaacgcc cgagccgccc gctcgcttct5401 ccaggccgga gccgataaag atgcccagga caacagggag cagacgccgc tattcctggc5461 ggcgcgggaa ggagcggtgg aagtagccca gctactgctg gggctggggg cagcccgaga5521 gctgcgggac caggctgggc tagcgccggc ggacgtcgct caccaacgta accactggga5581 tctgctgacg ctgctggaag gggctgggcc accagaggcc cgtcacaaag ccacgccggg5641 ccgcgaggct gggcccttcc cgcgcgcacg gacggtgtca gtaagcgtgc ccccgcatgg5701 gggcggggct ctgccgcgct gccggacgct gtcagccgga gcaggccctc gtgggggcgg5761 agcttgtctg caggctcgga cttggtccgt agacttggct gcgcgggggg gcggggccta5821 ttctcattgc cggagcctct cgggagtagg agcaggagga ggcccgaccc ctcgcggccg5881 taggttttct gcaggcatgc gcgggcctcg gcccaaccct gcgataatgc gaggaagata5941 cggagtggct gccgggcgcg gaggcagggt ctcaacggat gactggccct gtgattgggt6001 ggccctggga gcttgcggtt ctgcctccaa cattccgatc ccgcctcctt gccttactcc6061 gtccccggag cggggatcac ctcaacttga ctgtggtccc ccagccctcc aagaaatgcc6121 cataaaccaa ggaggagagg gtaaaaaata gaagaataca tggtagggag gaattccaaa6181 aatgattacc cattaaaagg caggctggaa ggccttcctg gttttaagat ggatccccca6241 aaatgaaggg ttgtgagttt agtttctctc ctaaaatgaa tgtatgccca ccagagcaga
6301 catcttccac gtggagaagc tgcagctctg gaaagagggt ttaagatgct aggatgaggc6361 aggcccagtc ctcctccaga aaataagaca ggccacagga gggcagagtg gagtggaaat6421 acccctaagt tggaaccaag aattgcaggc atatgggatg taagatgttc tttcctatat6481 atggtttcca aagggtgccc ctatgatcca ttgtccccac tgcccacaaa tggctgacaa6541 atatttattg ggcacctact atgtgccagg cactgtgtag gtgctgaaaa gtggccaagg6601 gccacccccg ctgatgactc cttgcattcc ctcccctcac aacaaagaac tccactgtgg6661 ggatgaagcg cttcttctag ccactgctat cgctatttaa gaaccctaaa tctgtcaccc6721 ataataaagc tgatttgaag tgttaaaaaa aaaaaaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>26<211>581<212>DNA<213>人類(Homo sapiens)<400>261 ttcaccaatg tttatatcaa aaactttggg gaagaggtgg atgatgagag tctgaaagag61 ctattcagtc agtttggtaa gaccctaagt gtcaaggtga tgagagatcc caatgggaaa121 tccaaaggct ttggctttgt gagttacgaa aaacacgagg atgccaataa ggctgtggaa181 gagatgaatg gaaaagaaat aagtggtaaa atcatatttg taggccgtgc acaaaagaaa241 gtagaacggc aggcagagtt aaaacggaaa tttgaacagt tgaaacagga gagaattagt301 cgatatcagg gggtgaatct ctacattaag aacttggatg acactattga tgatgagaaa361 ttaaggaaag aattttctcc ttttggatca attaccagtg ctaaggtaat gctggaggat421 ggaagaagca aagggtttgg cttcgtctgc ttctcatctc ctgaagaagc aaccaaagca481 gtcactgaga tgaatggacg cattgtgggc tccaagccac tatatgttgc cctggcccag541 aggaaggaag agagaaaggc tcacctgacc aaccccgaat t<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>27<211>2966<212>DNA<213>人類(Homo sapiens)<400>271 cgcccgagcc gcgcgcggag ctgccggggg ctccttagca cccgggcgcc ggggccctcg61 cccttccgca gccttcactc cagccctctg ctcccgcacg ccatgaagtc gccgttctac121 cgctgccaga acaccacctc tgtggaaaaa ggcaactcgg cggtgatggg cggggtgctc181 ttcagcaccg gcctcctggg caacctgctg gccctggggc tgctggcgcg ctcggggctg241 gggtggtgct cgcggcgtcc actgcgcccg ctgccctcgg tcttctacat gctggtgtgt301 ggcctgacgg tcaccgactt gctgggcaag tgcctcctaa gcccggtggt gctggctgcc361 tacgctcaga accggagtct gcgggtgctt gcgcccgcat tggacaactc gttgtgccaa421 gccttcgcct tcttcatgtc cttctttggg ctctcctcga cactgcaact cctggccatg481 gcactggagt gctggctctc cctagggcac cctttcttct accgacggca catcaccctg541 cgcctgggcg cactggtggc cccggtggtg agcgccttct ccctggcttt ctgcgcgcta601 cctttcatgg gcttcgggaa gttcgtgcag tactgccccg gcacctggtg ctttatccag661 atggtccacg aggagggctc gctgtcggtg ctggggtact ctgtgctcta ctccagcctc
721 atggcgctgc tggtcctcgc caccgtgctg tgcaacctcg gcgccatgcg caacctctat781 gcgatgcacc ggcggctgca gcggcacccg cgctcctgca ccagggactg tgccgagccg841 cgcgcggacg ggagggaagc gtcccctcag cccctggagg agctggatca cctcctgctg901 ctggcgctga tgaccgtgct cttcactatg tgttctctgc ccgtaattta tcgcgcttac961 tatggagcat ttaaggatgt caaggagaaa aacaggacct ctgaagaagc agaagacctc1021 cgagccttgc gatttctatc tgtgatttca attgtggacc cttggatttt tatcattttc1081 agatctccag tatttcggat attttttcac aagattttca ttagacctct taggtacagg1141 agccggtgca gcaattccac taacatggaa tccagtctgt gacagtgttt ttcactctgt1201 ggtaagctga ggaatatgtc acattttcag tcaaagaacc atgattaaaa aaaaaaagac1261 aacttacaat ttaaatcctt aaaagttacc tcccataaca aaagcatgta tatgtatttt1321 caaaagtatt tgatatctta acaatgtgtt accattctat agtcatgaac cccttcagtg1381 cattttcatt tttttattaa cagcaactaa aattttatat attgtaacca gtgttaaaag1441 tcttaaaaaa caatggtatt aattgtccct acatttgtgc ttggtggccc tatttttttt1501 ttttagagag gccttgagac atacaggtct tttaaaatac agtagaaaca ccactgttta1561 cgattatacg atggacattc ataaaaagca taatttctta ccctattcat tttttggtga1621 aacctgattc attgatttta tatcattgcc gatgtttagt tcatttcttt gccaattgat1681 ctaagcatag cctgaattat gatgttcctc agagaagtga ggtgggaaat atgaccaggt1741 caggcagttg gaggggcttc cccagccacc atcggggagt acttgctgcc tcaggtggag1801 acctgaagct gtaactagat gcagagcaag atatgactat agcccacaac ccaaagaagc1861 aaaaattcgt ttttatcttt tgaaatccag tttcttttgt attgagtcaa gggtgtcagt1921 aggaatcaaa agttgggggt gggttgcaaa atgttctttc agtttttaga acctccattt1981 tataaaagaa ttatcctatc aatggattct ttagtggaag gatttatgct tctttgaaaa2041 ccagtgtgtg actcactgta gagccatgtt tactgtttga ctgtgtggca caggggggca2101 tttggcacag caaaaagccc acccaggact tagcctcagt tgacgatagt aacaatggcc2161 ttaacatcta ccttaacagc tacctattac agccgtattc tgctgtccgt ggagacggta2221 agatcttagg ttccaagatt ttacttcaaa ttacaccttc aaaactggag cagcatatag2281 ccgaaaagga gcacaactga gcactttaat agtaatttaa aagttttcaa gggtcagcaa2341 tatgatgact gaaagggaaa agtggaggaa acgcagctgc aactgaagcg gagactctaa2401 acccagcttg caggtaagag ctttcacctt tggtaaaaga acagctgggg aggttcaagg2461 ggtttcagca tctctggagt tcctttgtat ctgacaatct caggactcca aggtgcaaag2521 cctgctgcat ttgcgtgatc tcaagacctc cagccagaag tcccttccaa atataagagt2581 actcatgttt atttatttcc aactgagcag caacctcctt tgtttcactt atgttttttc2641 cagtatctga gataatataa agctgggtaa ttttttatgt aattttttgg tatagcaaaa2701 ctgtgaaaaa gccaaattag gcatacaagg agtatgattt aacagtatga catgatgaaa2761 aaaatacagt tgtttttgaa atttaacttt tgtttgtacc ttcaatgtgt aagtacatgc2821 atgttttatt gtcagaggaa gaacatgttt tttgtattct ttttttggag aggtgtgtta2881 ggataattgt ccagttaatt tgaaaaggcc ccagatgaat caataaatat aattttatag2941 taaaaaaaaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>28<211>2403<212>DNA<213>人類(Homo sapiens)<400>281 tttgcaggtg cctcaggaac cctgaagctg ggctgagcca tgatgctgct gccagaaccc
61 ctgcagaggg cctggtttca ggagactcag agtcctctgt gaaaaagccc ttggagagcg121 ccccagcagg gctgcacttg gctcctgtga ggaaggggct caggggtctg ggcccctccg181 cctgggccgg gctgggagcc aggcgggcgg ctgggctgca gcaatggacc gtgagctggc241 ccagcccgcg tccgtgctga gcctgcctgt cgtctgtggc catgcccatc atgggctcct301 cggtgtacat cacggtggag ctggccattg ctgtgctggc catcctgggc aatgtgctgg361 tgtgctgggc cgtgtggctc aagagcaacc tgcagaacgt caccaactac tttgtggtgt421 cactggcggc ggccgacatc gcagtgggtg tgctcgccat cccctttgcc atcaccatca481 gcaccgggtt ctgcgctgcc tgccacggct gcctcttcat tgcctgcttc gtcctggtcc541 tcacgcagag ctccatcttc agtctcctgg ccatcgccat tgaccgctac attgccatcc601 gcatcccgct ccggtacaat ggcttggtga ccggcacgag ggctaagggc atcattgcca661 tctgctgggt gctgtcgttt gccatcggcc tgactcccat gctaggttgg aacaactgcg721 gtcagccaaa ggagggcaag aaccactccc agggctgcgg ggagggccaa gtggcctgtc781 tctttgagga tgtggtcccc atgaactaca tggtgtactt caacttcttt gcctgtgtgc841 tggtgcccct gctgctcatg ctgggtgtct atttgcggat cttcctggcg gcgcgacgac901 agctgaagca gatggagagc cagcctctgc cgggggagcg ggcacggtcc acactgcaga961 aggaggtcca tgctgccaag tcactggcca tcattgtggg gctctttgcc ctctgctggc1021 tgcccctaca catcatcaac tgcttcactt tcttctgccc cgactgcagc cacgcccctc1081 tctggctcat gtacctggcc atcgtcctct cccacaccaa ttcggttgtg aatcccttca1141 tctacgccta ccgtatccgc gagttccgcc agaccttccg caagatcatt cgcagccacg1201 tcctgaggca gcaagaacct ttcaaggcag ctggcaccag tgcccgggtc ttggcagctc1261 atggcagtga cggagagcag gtcagcctcc gtctcaacgg ccacccgcca ggagtgtggg1321 ccaacggcag tgctccccac cctgagcgga ggcccaatgg ctatgccctg gggctggtga1381 gtggagggag tgcccaagag tcccagggga acacgggcct cccagacgtg gagctcctta1441 gccatgagct caagggagtg tgcccagagc cccctggcct agatgacccc ctggcccagg1501 atggagcagg agtgtcctga tgattcatgg agtttgcccc ttcctaaggg aaggagatct1561 ttatctttct ggttggcttg accagtcagg ttgggagaag agagagagtg ccaggagacc1621 ctgagggcag ccggttccta ctttggactg agagaaggga gccccaggct ggagcagcat1681 gaggcccagc aagaagggct tgggttctga ggaagcagat gtttcatgct gtgaggcctt1741 gcaccaggtg ggggccacag caccagcagc atctttgctg ggcaggccca gccctccact1801 gcagaagcat ctggaagcac caccttgtct ccacagagca gcttgggcac agcagactgg1861 cctggccctg agactgggga gtggctccaa tagcctcctg ccacccacac accactctcc1921 ctagactctc ctagggttca ggagctgctg ggcccagagg tgacatttga cttttttcca1981 ggaaaaatgt aagtgtgagg aaaccctttt tattttatta cctttcactc tctggctgct2041 gggtctgccg tcggtcctgc tgctaacctg gcaccagagc ctctgcccgg ggagcctcag2101 gcagtcctct cctgctgtca cagctgccat ccacttctca gtcccagggc catctcttgg2161 agtgacaaag ctgggatcaa ggatagggag ttgtaacaga gcagtgccag agcatgggcc2221 caggtcccag gggagaggtt ggggctggca ggccactggc atgtgctgag tagcgcagag2281 ctacccagtg agaggccttg tctaactgcc tttccttcta aagggaatgt ttttttctga2341 gataaaataa aaacgagcca catcgtgttt taagcttgtc caaatgaaaa aaaaaaaaaa2401 aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>29<211>3592<212>DNA<213>人類(Homo sapiens)
<400>291 ggcggggggc gcacagagcc agaggggctt gcgagcggcg gctgagggac cgcggggagg61 gggcgccgag cggctccagc gcagagactc tcactgcacg ccggaggccc cttcctcgct121 ccgcccgcgc gaccgcgcgc cccagtcccg ccccgccccg ctaaccgccc cagacacagc181 gctcgccgag ggtcgcttgg accctgatct tacccgtggg caccctgcgc tctgcctgcc241 gcgaagaccg gctccccgac ccgcagaagt caggagagag ggtgaagcgg agcagcccga301 ggcggggcag cctcccggag cagcgccgcg cagagcccgg gacaatgggg ccgcggcggc361 tgctgctggt ggccgcctgc ttcagtctgt gcggcccgct gttgtctgcc cgcacccggg421 cccgcaggcc agaatcaaaa gcaacaaatg ccaccttaga tccccggtca tttcttctca481 ggaaccccaa tgataaatat gaaccatttt gggaggatga ggagaaaaat gaaagtgggt541 taactgaata cagattagtc tccatcaata aaagcagtcc tcttcaaaaa caacttcctg601 cattcatctc agaagatgcc tccggatatt tgaccagctc ctggctgaca ctctttgtcc661 catctgtgta caccggagtg tttgtagtca gcctcccact aaacatcatg gccatcgttg721 tgttcatcct gaaaatgaag gtcaagaagc cggcggtggt gtacatgctg cacctggcca781 cggcagatgt gctgtttgtg tctgtgctcc cctttaagat cagctattac ttttccggca841 gtgattggca gtttgggtct gaattgtgtc gcttcgtcac tgcagcattt tactgtaaca901 tgtacgcctc tatcttgctc atgacagtca taagcattga ccggtttctg gctgtggtgt961 atcccatgca gtccctctcc tggcgtactc tgggaagggc ttccttcact tgtctggcca1021 tctgggcttt ggccatcgca ggggtagtgc ctctcgtcct caaggagcaa accatccagg1081 tgcccgggct caacatcact acctgtcatg atgtgctcaa tgaaaccctg ctcgaaggct1141 actatgccta ctacttctca gccttctctg ctgtcttctt ttttgtgccg ctgatcattt1201 ccacggtctg ttatgtgtct atcattcgat gtcttagctc ttccgcagtt gccaaccgca1261 gcaagaagtc ccgggctttg ttcctgtcag ctgctgtttt ctgcatcttc atcatttgct1321 tcggacccac aaacgtcctc ctgattgcgc attactcatt cctttctcac acttccacca1381 cagaggctgc ctactttgcc tacctcctct gtgtctgtgt cagcagcata agctcgtgca1441 tcgaccccct aatttactat tacgcttcct ctgagtgcca gaggtacgtc tacagtatct1501 tatgctgcaa agaaagttcc gatcccagca gttataacag cagtgggcag ttgatggcaa1561 gtaaaatgga tacctgctct agtaacctga ataacagcat atacaaaaag ctgttaactt1621 aggaaaaggg actgctggga ggttaaaaag aaaagtttat aaaagtgaat aacctgagga1681 ttctattagt ccccacccaa actttattga ttcacctcct aaaacaacag atgtacgact1741 tgcatacctg ctttttatgg gagctgtcaa gcatgtattt ttgtcaatta ccagaaagat1801 aacaggacga gatgacggtg ttattccaag ggaatattgc caatgctaca gtaataaatg1861 aatgtcactt ctggatatag ctaggtgaca tatacatact tacatgtgtg tatatgtaga1921 tgtatgcaca cacatatatt atttgcagtg cagtatagaa taggcacttt aaaacactct1981 ttccccgcac cccagcaatt atgaaaataa tctctgattc cctgatttaa tatgcaaagt2041 ctaggttggt agagtttagc cctgaacatt tcatggtgtt catcaacagt gagagactcc2101 atagtttggg cttgtaccac ttttgcaaat aagtgtattt tgaaattgtt tgacggcaag2161 gtttaagtta ttaagaggta agacttagta ctatctgtgc gtagaagttc tagtgttttc2221 aattttaaac atatccaagt ttgaattcct aaaattatgg aaacagatga aaagcctctg2281 ttttgatatg ggtagtattt tttacatttt acacactgta cacataagcc aaaactgagc2341 ataagtcctc tagtgaatgt aggctggctt tcagagtagg ctattcctga gagctgcatg2401 tgtccgcccc cgatggagga ctccaggcag cagacacatg ccagggccat gtcagacaca2461 gattggccag aaaccttcct gctgagcctc acagcagtga gactggggcc actacatttg2521 ctccatcctc ctgggattgg ctgtgaactg atcatgttta tgagaaactg gcaaagcaga2581 atgtgatatc ctaggaggta atgaccatga aagacttctc tacccatctt aaaaacaacg2641 aaagaaggca tggacttctg gatgcccatc cactgggtgt aaacacatct agtagttgtt2701 ctgaaatgtc agttctgata tggaagcacc cattatgcgc tgtggccact ccaataggtg2761 ctgagtgtac agagtggaat aagacagaga cctgccctca agagcaaagt agatcatgca
2821 tagagtgtga tgtatgtgta ataaatatgt ttcacacaaa caaggcctgt cagctaaaga2881 agtttgaaca tttgggttac tatttcttgt ggttataact taatgaaaac aatgcagtac2941 aggacatata ttttttaaaa taagtctgat ttaattgggc actatttatt tacaaatgtt3001 ttgctcaata gattgctcaa atcaggtttt cttttaagaa tcaatcatgt cagtctgctt3061 agaaataaca gaagaaaata gaattgacat tgaaatctag gaaaattatt ctataatttc3121 catttactta agacttaatg agactttaaa agcatttttt aacctcctaa gtatcaagta3181 tagaaaatct tcatggaatt cacaaagtaa tttggaaatt aggttgaaac atatctctta3241 tcttacgaaa aaatggtagc attttaaaca aaatagaaag ttgcaaggca aatgtttatt3301 taaaagagca ggccaggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggctga3361 ggcgggtgga tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaacccgt3421 ctctactaaa aatgcaaaaa aaattagccg ggcgtggtgg caggcacctg tagtcccagc3481 tactcgggag gctgaggcag gagactggcg tgaacccagg aggcggacct tgtagtgagc3541 cgagatcgcg ccactgtgct ccagcctggg caacagagca agactccatc tc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>30<211>2876<212>DNA<213>人類(Homo sapiens)<400>301 tgaaacctaa cccgccctgg ggaggcgcgc agcagaggct ccgattcggg gcaggtgaga61 ggctgacttt ctctcggtgc gtccagtgga gctctgagtt tcgaatcggc ggcggcggat121 tccccgcgcg cccggcgtcg gggcttccag gaggatgcgg agccccagcg cggcgtggct181 gctgggggcc gccatcctgc tagcagcctc tctctcctgc agtggcacca tccaaggaac241 caatagatcc tctaaaggaa gaagccttat tggtaaggtt gatggcacat cccacgtcac301 tggaaaagga gttacagttg aaacagtctt ttctgtggat gagttttctg catctgtcct361 cactggaaaa ctgaccactg tcttccttcc aattgtctac acaattgtgt ttgtggtggg421 tttgccaagt aacggcatgg ccctgtgggt ctttcttttc cgaactaaga agaagcaccc481 tgctgtgatt tacatggcca atctggcctt ggctgacctc ctctctgtca tctggttccc541 cttgaagatt gcctatcaca tacatggcaa caactggatt tatggggaag ctctttgtaa601 tgtgcttatt ggctttttct atggcaacat gtactgttcc attctcttca tgacctgcct661 cagtgtgcag aggtattggg tcatcgtgaa gcccatgggg cactccagga agaaggcaaa721 cattgccatt ggcatctccc tggcaatatg gctgctgatt ctgctggtca ccatcccttt781 gtatgtcgtg aagcagacca tcttcattcc tgccctgaac atcacgacct gtcatgatgt841 tttgcctgag cagctcttgg tgggagacat gttcaattac ttcctctctc tggccattgg901 ggtctttctg ttcccagcct tcctcacagc ctctgcctat gtgctgatga tcagaatgct961 gcgatcttct gccatggatg aaaactcaga gaagaaaagg aagagggcca tcaaactcat1021 tgtcactgtc ctggccatgt acctgatctg cttcactcct agtaaccttc tgcttgtggt1081 gcattatttt ctgattaaga gccagggcca gagccatgtc tatgccctgt acattgtagc1141 cctctgcctc tctaccctta acagctgcat cgaccccttt gtctattact ttgtttcaca1201 tgatttcagg gatcatgcaa agaacgctct cctttgccga agtgtccgca ctgtaaagca1261 gatgcaagta tccctcacct caaagaaaca ctccaggaaa tccagctctt actcttcaag1321 ttcaaccact gttaagacct cctattgagt tttccaggtc ctcagatggg aattgcacag1381 taggatgtgg aacctgttta atgttatgag gacgtgtctg ttatttccta atcaaaaagg1441 tctcaccaca taccatgtgg atgcagcacc tctcaggatt gctaggagct cccctgtttg1501 catgagaaaa gtagtccccc aaattaacat cagtgtctgt ttcagaatct ctctactcag
1561 atgaccccag aaactgaacc aacagaagca gacttttcag aagatggtga agacagaaac1621 ccagtaactt gcaaaaagta gacttggtgt gaagactcac ttctcagctg aaattatata1681 tatacacata tatatatttt acatctggga tcatgataga cttgttaggg cttcaaggcc1741 ctcagagatg atcagtccaa ctgaacgacc ttacaaatga ggaaaccaag ataaatgagc1801 tgccagaatc aggtttccaa tcaacagcag tgagttggga ttggacagta gaatttcaat1861 gtccagtgag tgaggttctt gtaccacttc atcaaaatca tggatcttgg ctgggtgcgg1921 tgcctcatgc ctgtaatcct agcactttgg gaggctgagg caggcaatca cttgaggtca1981 ggagttcgag accagcctgg ccatcatggc gaaacctcat ctctactaaa aatacaaaag2041 ttaaccaggt gtgtggtgca cgtttgtaat cccagttact caggaggctg aggcacaaga2101 attgagtatc actttaactc aggaggcaga ggttgcagtg agccgagatt gcaccactgc2161 actccagctt gggtgataaa ataaaataaa atagtcgtga atcttgttca aaatgcagat2221 tcctcagatt caataatgag agctcagact gggaacaggg cccaggaatc tgtgtggtac2281 aaacctgcat ggtgtttatg cacacagaga tttgagaacc attgttctga atgctgcttc2341 catttgacaa agtgccgtga taatttttga aaagagaagc aaacaatggt gtctctttta2401 tgttcagctt ataatgaaat ctgtttgttg acttattagg actttgaatt atttctttat2461 taaccctctg agtttttgta tgtattatta ttaaagaaaa atgcaatcag gattttaaac2521 atgtaaatac aaattttgta taacttttga tgacttcagt gaaattttca ggtagtctga2581 gtaatagatt gttttgccac ttagaatagc atttgccact tagtatttta aaaaataatt2641 gttggagtat ttattgtcag ttttgttcac ttgttatcta atacaaaatt ataaagcctt2701 cagagggttt ggaccacatc tctttggaaa atagtttgca acatatttaa gagatacttg2761 atgccaaaat gactttatac aacgattgta tttgtgactt ttaaaaataa ttattttatt2821 gtgtaattga tttataaata acaaaatttt ttttacaact taaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>31<211>1629<212>DNA<213>人類(Homo sapiens)<400>311 acacatcagg ggcttgctct tgcaaaacca aaccacaaga cagacttgca aaagaaggca61 tgcacagctc agcactgctc tgttgcctgg tcctcctgac tggggtgagg gccagcccag121 gccagggcac ccagtctgag aacagctgca cccacttccc aggcaacctg cctaacatgc181 ttcgagatct ccgagatgcc ttcagcagag tgaagacttt ctttcaaatg aaggatcagc241 tggacaactt gttgttaaag gagtccttgc tggaggactt taagggttac ctgggttgcc301 aagccttgtc tgagatgatc cagttttacc tggaggaggt gatgccccaa gctgagaacc361 aagacccaga catcaaggcg catgtgaact ccctggggga gaacctgaag accctcaggc421 tgaggctacg gcgctgtcat cgatttcttc cctgtgaaaa caagagcaag gccgtggagc481 aggtgaagaa tgcctttaat aagctccaag agaaaggcat ctacaaagcc atgagtgagt541 ttgacatctt catcaactac atagaagcct acatgacaat gaagatacga aactgagaca601 tcagggtggc gactctatag actctaggac ataaattaga ggtctccaaa atcggatctg661 gggctctggg atagctgacc cagccccttg agaaacctta ttgtacctct cttatagaat721 atttattacc tctgatacct caacccccat ttctatttat ttactgagct tctctgtgaa781 cgatttagaa agaagcccaa tattataatt tttttcaata tttattattt tcacctgttt841 ttaagctgtt tccatagggt gacacactat ggtatttgag tgttttaaga taaattataa901 gttacataag ggaggaaaaa aaatgttctt tggggagcca acagaagctt ccattccaag961 cctgaccacg ctttctagct gttgagctgt tttccctgac ctccctctaa tttatcttgt
1021 ctctgggctt ggggcttcct aactgctaca aatactctta ggaagagaaa ccagggagcc1081 cctttgatga ttaattcacc ttccagtgtc tcggagggat tcccctaacc tcattcccca1141 accacttcat tcttgaaagc tgtggccagc ttgttattta taacaaccta aatttggttc1201 taggccgggc gcggtggctc acgcctgtaa tcccagcact ttgggaggct gaggcgggtg1261 gatcacttga ggtcaggagt tcctaaccag cctggtcaac atggtgaaac cccgtctcta1321 ctaaaaatac aaaaattagc cgggcatggt ggcgcgcacc tgtaatccca gctacttggg1381 aggctgaggc aagagaattg cttgaaccca ggagatggaa gttgcagtga gctgatatca1441 tgcccctgta ctccagcctg ggtgacagag caagactctg tctcaaaaaa taaaaataaa1501 aataaatttg gttctaatag aactcagttt taactagaat ttattcaatt cctctgggaa1561 tgttacattg tttgtctgtc ttcatagcag attttaattt tgaataaata aatgtatctt1621 attcacatc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>32<211>1185<212>DNA<213>人類(Homo sapiens)<400>321 gctcagggca catgcctccc ctccccaggc cgcggcccag ctgaccctcg gggctccccc61 ggcagcggac agggaagggt taaaggcccc cggctccctg ccccctgccc tggggaaccc121 ctggccctgt ggggacatga actgtgtttg ccgcctggtc ctggtcgtgc tgagcctgtg181 gccagataca gctgtcgccc ctgggccacc acctggcccc cctcgagttt ccccagaccc241 tcgggccgag ctggacagca ccgtgctcct gacccgctct ctcctggcgg acacgcggca301 gctggctgca cagctgaggg acaaattccc agctgacggg gaccacaacc tggattccct361 gcccaccctg gccatgagtg cgggggcact gggagctcta cagctcccag gtgtgctgac421 aaggctgcga gcggacctac tgtcctacct gcggcacgtg cagtggctgc gccgggcagg481 tggctcttcc ctgaagaccc tggagcccga gctgggcacc ctgcaggccc gactggaccg541 gctgctgcgc cggctgcagc tcctgatgtc ccgcctggcc ctgccccagc cacccccgga601 cccgccggcg cccccgctgg cgcccccctc ctcagcctgg gggggcatca gggccgccca661 cgccatcctg ggggggctgc acctgacact tgactgggcc gtgaggggac tgctgctgct721 gaagactcgg ctgtgacccg gggcccaaag ccaccaccgt ccttccaaag ccagatctta781 tttatttatt tatttcagta ctgggggcga aacagccagg tgatcccccc gccattatct841 ccccctagtt agagacagtc cttccgtgag gcctggggga catctgtgcc ttatttatac901 ttatttattt caggagcagg ggtgggaggc aggtggactc ctgggtcccc gaggaggagg961 ggactggggt cccggattct tgggtctcca agaagtctgt ccacagactt ctgccctggc1021 tcttccccat ctaggcctgg gcaggaacat atattattta tttaagcaat tacttttcat1081 gttggggtgg ggacggaggg gaaagggaag cctgggtttt tgtacaaaaa tgtgagaaac1141 ctttgtgaga cagagaacag ggaattaaat gtgtcataca tatcc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>33<211>3122<212>DNA<213>人類(Homo sapiens)
<400>331 tcggcggaga cctgctcccc agaagacgcc tcctgcttcc cactgcgccc tggaggacgc61 gggctggctg ctgggcgagc tcggcggagg cacgcccctc gcctccccgc ggagtgcgga121 ctcgccccgg tgcccaaact ccgcccaccc tctagggagc tccgctctcc cgcctaaccc181 cggcactccg gacagagctg ggcctgggga aggggttcct gaactacgcg gacgccgaac241 gggacgcgct gcagaagcgc acgagtctgc ggccacgcgc gctccgatgg ctgccaggag301 ctgagctcag ggtgggcgga ggaagcggtt agacgccccg aaactgagct gcacgtttct361 aaggtaggga ggaggaagat gcccccaatt aagttgatct ttgagccaag gaggctgggg421 agcagcctcc ccaagctaga gccctgcaga gcgagtttcc cttgacctcg ctgcgcctct481 ggcgcgctct gcagcgcgga cccgcggccc ctcgggaaag cgcagtcgga aagttatccg541 cggcggttcc ctgcgcgccc tgttgtgtaa gctcggcgtt gccagcggac ggagaagttg601 ctggcttgcc cgatagccca gttcggtggc ggcccggggc ggatttcatg gcccgcggcg661 aacgcggggc cagagctggc gtgggcgagc ccctgcgcgc cccctcccgc ggggatccag721 ttcgcctgct cccttccgct cgctggcttt tccgatgctt gctgcgcccc tggccgccgc781 tgccctctcg ccgcctccta cccctcggag ccgccgccta agtcgaggag gagagaatga841 ccgaggtgct gtggccggct gtccccaacg ggacggacgc tgccttcctg gccggtccgg901 gttcgtcctg ggggaacagc acggtcgcct ccactgccgc cgtctcctcg tcgttcaaat961 gcgccttgac caagacgggc ttccagtttt actacctgcc ggctgtctac atcttggtat1021 tcatcatcgg cttcctgggc aacagcgtgg ccatctggat gttcgtcttc cacatgaagc1081 cctggagcgg catctccgtg tacatgttca atttggctct ggccgacttc ttgtacgtgc1141 tgactctgcc agccctgatc ttctactact tcaataaaac agactggatc ttcggggatg1201 ccatgtgtaa actgcagagg ttcatctttc atgtgaacct ctatggcagc atcttgtttc1261 tgacatgcat cagtgcccac cggtacagcg gtgtggtgta ccccctcaag tccctgggcc1321 ggctcaaaaa gaagaatgcg atctgtatca gcgtgctggt gtggctcatt gtggtggtgg1381 cgatctcccc catcctcttc tactcaggta ccggggtccg caaaaacaaa accatcacct1441 gttacgacac cacctcagac gagtacctgc gaagttattt catctacagc atgtgcacga1501 ccgtggccat gttctgtgtc cccttggtgc tgattctggg ctgttacgga ttaattgtga1561 gagctttgat ttacaaagat ctggacaact ctcctctgag gagaaaatcg atttacctgg1621 taatcattgt actgactg tttttgctg tgtcttacatccc tttccatgtg atgaaaacga1681 tgaacttgag ggcccggctt gattttcaga ccccagcaat gtgtgctttc aatgacaggg1741 tttatgccac gtatcaggtg acaagaggtc tagcaagtct caacagttgt gtggacccca1801 ttctctattt cttggcggga gatactttca gaaggagact ctcccgagcc acaaggaaag1861 cttctagaag aagtgaggca aatttgcaat ccaagagtga agacatgacc ctcaatattt1921 tacctgagtt caagcagaat ggagatacaa gcctgtgaag gcacaagaat ctccaaacac1981 ctctctgttg taatatggta ggatgcttaa cagaatcaag tacttttccc ctctttaact2041 ttctagttta gaaaaaaatc aaaccaagaa aatagtgagt taaaaaaata atagaagtag2101 aaatgcccac atccacactt agcttgtttg ggtttgcttt cacagtctct cttccttctg2161 actagaagta tgtataataa aacaatacta cctagttaaa catttacttt ctcttttgcc2221 tttaaaatgt gcaggctttt ctgtttaaag tgtgtgtgca catgagtact ggggctgttt2281 ttgatattag taatttctct aagaaaacta gccccctgca acttgagttt gtggtttatc2341 tagcctttat tgttttttta aaatccacag taggaataaa aaatctatat tctcagaaat2401 atctagcatg gtatataaca aaacactaaa ctcatcagtt catccggcat cagatcaatg2461 gatctctgag cggggtgttt ttttcagtgt cttataagca tagatgatag ttgactgagt2521 ttctttaggg cattgaatag acaagtaaag ctaatgaatt taaaagcctg aaaagtgatt2581 gttttccagt tatttctgga aaaggtctca ttatatattg ggtgctaaat gtttgatggg2641 gaaagcctgc atatattatc gtactggtaa aatgcattca aaataattaa agtgcatgta2701 ttttccttgt aaacaccatg agctctctta gacatcttgt gataaagagc atttacttgc2761 cccactgctg tgcaatgcct taggactttg tttgtgttcc aggacaagtg ttcactcaca
2821 tctgtaaaaa caattttaag aattgcaaat aaattacaga ccaaagattg agtaaagtca2881 aataactgtt agtaagttga aggatattgg acaggaggac agtatttcag aaaaggagag2941 gttgacagtc atccacaagg catagcctcc aagtatactc tcaaatgtat gaagcaactg3001 gggtgggcag aagacatttt agaatgaggg ctttagttta aattaaagtc atggtggaga3061 agactcttgc ttcctccaag tgtttgaaaa cacaaaatgc gatatgaaaa aaaaaaaaaa3121 aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>34<211>2395<212>DNA<213>人類(Homo sapiens)<400>341 gccgccgtcg gcgcgctggg tgcgggaagg gggctctgga tttcggtccc tccccttttt61 cctctgagtc tcggaacgct ccagctctca gaccctcttc ctcccaggta aaggccggga121 gaggagggcg catctctttt ccaggcaccc caccatgggc aatgcctcca atgactccca181 gtctgaggac tgcgagacgc gacagtggct tcccccaggc gaaagcccag ccatcagctc241 cgtcatgttc tcggccgggg tgctggggaa cctcatagca ctggcgctgc tggcgcgccg301 ctggcggggg gacgtggggt gcagcgccgg ccgcaggagc tccctctcct tgttccacgt361 gctggtgacc gagctggtgt tcaccgacct gctcgggacc tgcctcatca gcccagtggt421 actggcttcg tacgcgcgga accagaccct ggtggcactg gcgcccgaga gccgcgcgtg481 cacctacttc gctttcgcca tgaccttctt cagcctggcc acgatgctca tgctcttcgc541 catggccctg gagcgctacc tctcgatcgg gcacccctac ttctaccagc gccgcgtctc601 gcgctccggg ggcctggccg tgctgcctgt catctatgca gtctccctgc tcttctgctc661 gctgccgctg ctggactatg ggcagtacgt ccagtactgc cccgggacct ggtgcttcat721 ccggcacggg cggaccgctt acctgcagct gtacgccacc ctgctgctgc ttctcattgt781 ctcggtgctc gcctgcaact tcagtgtcat tctcaacctc atccgcatgc accgccgaag841 ccggagaagc cgctgcggac cttccctggg cagtggccgg ggcggccccg gggcccgcag901 gagaggggaa agggtgtcca tggcggagga gacggaccac ctcattctcc tggctatcat961 gaccatcacc ttcgccgtct gctccttgcc tttcacgatt tttgcatata tgaatgaaac1021 ctcttcccga aaggaaaaat gggacctcca agctcttagg tttttatcaa ttaattcaat1081 aattgaccct tgggtctttg ccatccttag gcctcctgtt ctgagactaa tgcgttcagt1141 cctctgttgt cggatttcat taagaacaca agatgcaaca caaacttcct gttctacaca1201 gtcagatgcc agtaaacagg ctgacctttg aggtcagtag tttaaaagtt cttagttata1261 tagcatctgg aagatcattt tgaaattgtt ccttggagaa atgaaaacag tgtgtaaaca1321 aaatgaagct gccctaataa aaaggagtat acaaacattt aagctgtggt caaggctaca1381 gatgtgctga caaggcactt catgtaaagt gtcagaagga gctacaaaac ctaccctcag1441 tgagcatggt acttggcctt tggaggaaca atcggctgca ttgaagatcc agctgcctat1501 tgatttaagc tttcctgttg aatgacaaag tatgtggttt tgtaatttgt ttgaaacccc1561 aaacagtgac tgtactttct attttaatct tgctactacc gttatacaca tatagtgtac1621 agccagacta gattaaactt catatgtaat ctctaggaag tcaatatgtg gaagcaacca1681 agcctgctgt cttgtgatca cttagcgaac cctttatttg aacaatgaag ttgaaaatca1741 taggcacctt ttactgtgat gtttgtgtat gtgggagtac tctcatcact acagtattac1801 tcttacaaga gtggactcag tgggttaaca tcagttttgt ttactcatcc tccaggaact1861 gcaggtcaag ttgtcaggtt atttatttta taatgtccat atgctaatag tgatcaagaa1921 gactttagga atggttctct caacaagaaa taatagaaat gtctcaaggc agttaattct
1981 cattaatact cttattatcc tatttctggg ggaggatgta cgtggccatg tatgaagcca2041 aatattaggc ttaaaaactg aaaaatctgg ttcattcttc agatatactg gaaccctttt2101 aaagttgata ttggggccat gagtaaaata gattttataa gatgactgtg ttgtaccaaa2161 attcatctgt ctatatttta tttagggaac atggtttgac tcatcttata tgggaaacca2221 tgtagcagtg agtcatatct taatatattt ctaaatgttt ggcatgtaaa tgtaaactca2281 gcatcaaaat atttcagtga atttgcactg tttaatcata gttactgtgt aaactcatct2341 gaaatgttac aaaaataaac tataaaacaa aaatttgaaa aaaaaaaaaa aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>35<211>3466<212>DNA<213>人類(Homo sapiens)<400>351 gccccgcagt ttccgcgcta agggaacgag tgcgcggagg ggacgagcgg ctggaccaca61 gccggcgccc gatcaggatc tccgcgctgg gatcggtgga acttgaggca gcggcggcgc121 ggggcgccat ggcacaccga gcggctccgt cttctgctcc tcagagagcc cggctggcgg181 cctgggatga caagatgtct ggactgcaat cctgcacagt tttgagaggg agatgacttg241 agtggttggc ttttatctcc acaacaatgt ccatgaacaa ttccaaacag ctagtgtctc301 ctgcagctgc gcttctttca aacacaacct gccagacgga aaaccggctt tccgtatttt361 tttcagtaat cttcatgaca gtgggaatct tgtcaaacag ccttgccatc gccattctca421 tgaaggcata tcagagattt agacagaagt ccaaggcatc gtttctgctt ttggccagtg481 gcctggtaat cactgatttc tttggccatc tcatcaatgg agccatagca gtatttgtat541 atgcttctga taaagaatgg atccgctttg accaatcaaa tgtcctttgc agtatttttg601 gtatctgcat ggtgttttct ggtctgtgcc cacttcttct aggcagtgtg atggccattg661 agcggtgtat tggagtcaca aaaccaatat ttcattctac gaaaattaca tccaaacatg721 tgaaaatgat gttaagtggt gtgtgcttgt ttgctgtttt catagctttg ctgcccatcc781 ttggacatcg agactataaa attcaggcgt cgaggacctg gtgtttctac aacacagaag841 acatcaaaga ctgggaagat agattttatc ttctactttt ttcttttctg gggctcttag901 cccttggtgt ttcattgttg tgcaatgcaa tcacaggaat tacactttta agagttaaat961 ttaaaagtca gcagcacaga caaggcagat ctcatcattt ggaaatggta atccagctcc1021 tggcgataat gtgtgtctcc tgtatttgtt ggagcccatt tctggttaca atggccaaca1081 ttggaataaa tggaaatcat tctctggaaa cctgtgaaac aacacttttt gctctccgaa1141 tggcaacatg gaatcaaatc ttagatcctt gggtatatat tcttctacga aaggctgtcc1201 ttaagaatct ctataagctt gccagtcaat gctgtggagt gcatgtcatc agcttacata1261 tttgggagct tagttccatt aaaaattcct taaaggttgc tgctatttct gagtcaccag1321 ttgcagagaa atcagcaagc acctagctta ataggacagt aaatctgtgt ggggctagaa1381 caaaattaag acatgtttgg caatatttca gttagttaaa tacctgtagc ctaactggaa1441 aattcaggct tcatcatgta gtttgaagat actattgtca gattcaggtt ttgaaatttg1501 tcaaataaac aggataactg tacatttttc acttgttttt gccaatggga ggtagacaca1561 ataaaataat gccatgggag tcacactgaa agcaattttg agcttatctg tcttatttat1621 gctttgagtg aatcatctgt tgaggtctaa tgcctttact tggcctattt gccagagaac1681 atcttaatgc agcctgcata gtgaaatggt tattttgaga tcaccgctct gtagctaacc1741 cttataaact aggctcagta aaataaagca ctcttatttt ttgatctggc ctattttgcc1801 cctcattgtg tagcctcaat taacacatgc atggtcatga cacccagaat tcatgatggt1861 ttgttataac aacctctgca tattccaggt ctggcagaca ggttgcctga ccctgcaatc
1921 ctatctagaa tgggcccatt cttgtcatat ttgacaaata ggactgccta catttattat1981 tatgaaggtc gattgttgtt ggaagtgttt tttcatgtca tagattagca attttcaaat2041 aattattttt tctctgaaaa ttttgtgtgt gattgcacaa taaataattt ttagagaaac2101 aaaggctctt tctcagcaca ttgatgggca actagaatta cagcagtttc aaaactctac2161 catggataat gcaaacaaac cgaagctaca tgccaatgat aggtgcaaag aatattggca2221 aaaggtgctt taccttgagc cattatttgt gtcagagaac aaaagaaaca gaatcaatat2281 ataaaattca aagactatct gcagctagtg tgtttcttct ttacacacat atacacacag2341 acatcagaaa attctgttga gagcaggttc attaaatttg taagatggca tattctaaag2401 cctgtgctac cagtactaag aggggaagac tggcaatttg ccaagcactt ggggattatt2461 ataacaatta actaggagat caagagataa taatctctcc ccaaattttc caataataat2521 tgagactttt tctttgcttg tttgtgtaat tcaaccaaaa gaatttcaat acccattcaa2581 attgtcctag gtctatcaga aattagggaa ggtagtcctg ctttataata ggaaaatgta2641 tttctgtata agagttcttt gctttcatta acttggattc atttaaaaat taatcttccc2701 tgttaggctg atttcagatt ctctaggaaa tctgtgtaag taaccagaag acctttcaga2761 tggtttattt gctttcagca gagaatttat ttcatacagt tacttaagag tgttgatgtc2821 ttgtgaacag agatataagg aaccattctc catccttcct tatcatgctg ggtacaatgc2881 ttctatgaat atttccatgt attttgactg gggagaggca tggagaagaa actctcattc2941 aggggctcca ggatccttct ccttgaggct tctaaataaa tggcagaatt cttgctgtat3001 tgccatgatg tcaccctggc catgtgtact gacttgagga gatcttgcaa catggccatg3061 tgcaaggctt taaggagtga gagagatgtg tacatatctt aggagggtta tctatgttat3121 ctgagtatat gtttgggtaa ccaaattggt cttaaaaatg atgttaaccc aagaagtaga3181 catcaaaaat taaaaaaaaa aaaaggaatg tgttttcatt gttttaagtt tttcttctga3241 gtaaaacaaa attatagaaa acaaatgcaa caatgtgcac atctgactta agagtttcat3301 ttctgttatt atatgtgttg catgtagctt ggcgatttac tgtgtaatga ataatagact3361 ggaacatcta ccaataactt tcacataaat gttcaaaata gaagtgtatt ttttcaggtt3421 tctggaaata aatagtaaaa taaatggcaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>36<211>839<212>DNA<213>人類(Homo sapiens)<400>361 ccatttcaac tttaacacag catgatcgaa acatacaacc aaacttctcc ccgatctgcg61 gccactggac tgcccatcag catgaaaatt tttatgtatt tacttactgt ttttcttatc121 acccagatga ttgggtcagc actttttgct gtgtatcttc atagaaggtt ggacaagata181 gaagatgaaa ggaatcttca tgaagatttt gtattcatga aaacgataca gagatgcaac241 acaggagaaa gatccttatc cttactgaac tgtgaggaga ttaaaagcca gtttgaaggc301 tttgtgaagg atataatgtt aaacaaagag gagacgaaga aagaaaacag ctttgaaatg361 caaaaaggtg atcagaatcc tcaaattgcg gcacatgtca taagtgaggc cagcagtaaa421 acaacatctg tgttacagtg ggctgaaaaa ggatactaca ccatgagcaa caacttggta481 accctggaaa atgggaaaca gctgaccgtt aaaagacaag gactctatta tatctatgcc541 caagtcacct tctgttccaa tcgggaagct tcgagtcaag ctccatttat agccagcctc601 tgcctaaagt cccccggtag attcgagaga atcttactca gagctgcaaa tacccacagt661 tccgccaaac cttgcaggca acaatccatt cacttgggag gagtatttga attgtaacca721 ggtgcttcgg tgtttgtcaa tgtgactgat ccaagccaag tgagccatgg cactggctca
781 cgtcctttgg cttactcaaa ctctgaacag tgtcaccttg caggctgtgg tggagctga<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>37<211>1536<212>DNA<213>人類(Homo sapiens)<400>371 gattacggca agcttggcac gagggcaggc attgcccgag gccagccgag ccgccagagc61 cgcgggccgc gggggtgtcg cgggcccaac cccaggatgc tcccctgcac ctcctgccta121 cccgggtctc tactgctctg ggcgctgcta ctgttgctct tgggatcagc ttctcctcag181 gattctgaag agcccgacag ctacacggaa tgcacagatg gctatgagtg ggacccagac241 agccagcact gccgggatgt caacgagtgt ctgaccatcc ctgaggcctg caagggggaa301 atgaagtgca tcaaccacta cgggggctac ttgtgcctgc cccgctccgc tgccgtcatc361 aacgacctac acggcgaggg acccccgcca ccagtgcctc ccgctcaaca ccccaacccc421 tgcccaccag gctatgagcc cgacgatcag gacagctgtg tggatgtgga cgagtgtgcc481 caggccctgc acgactgtcg ccccagccag gactgccata acttgcctgg ctcctatcag541 tgcacctgcc ctgatggtta ccgcaagatc gggcccgagt gtgtggacat agacgagtgc601 cgctaccgct actgccagca ccgctgcgtg aacctgcctg gctccttccg ctgccagtgc661 gagccgggtt tccagctggg gcctaacaac cgctcctgtg ttgatgtgaa cgagtgtgac721 atgggggccc catgcgagca gcgctgcttc aactcctatg ggaccttcct gtgtcgctgc781 caccagggct atgagctgca tcgggatggc ttctcctgca gtgatattga tgagtgtagc841 tactccagct acctctgtca gtaccgctgc gtcaacgagc caggccgttt ctcctgccac901 tgcccacagg gttaccagct gctggccaca cgcctctgcc aagacattga tgagtgtgag961 tctggtgcgc accagtgctc cgaggcccaa acctgtgtca acttccatgg gggctaccgc1021 tgcgtggaca ccaaccgctg cgtggagccc tacatccagg tctctgagaa ccgctgtctc1081 tgcccggcct ccaaccctct atgtcgagag cagccttcat ccattgtgca ccgctacatg1141 accatcacct cggagcggag cgtgcccgct gacgtgttcc agatccaggc gacctccgtc1201 taccccggtg cctacaatgc ctttcagatc cgtgctggaa actcgcaggg ggacttttac1261 attaggcaaa tcaacaacgt cagcgccatg ctggtcctcg cccggccggt gacgggcccc1321 cgggagtacg tgctggacct ggagatggtc accatgaatt ccctcatgag ctaccgggcc1381 agctctgtac tgaggctcac cgtctttgta ggggcctaca ccttctgagg agcaggaggg1441 agccaccctc cctgcagcta ccctagctga ggagcctgtt gtgaggggca gaatgagaaa1501 ggcaataaag ggagaaagaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>38<211>1101<212>DNA<213>人類(Homo sapiens)<400>381 atttgaggaa ccatgtctcc atccccgacc gccctcttct gtcttgggct gtgtctgggg61 cgtgtgccag cgcagagtgg accgctcccc aagccctccc tccaggctct gcccagctcc121 ctggtgcccc tggagaagcc agtgaccctc cggtgccagg gacctccggg cgtggacctg
181 taccgcctgg agaagctgag ttccagcagg taccaggatc aggcagtcct cttcatcccg241 gccatgaaga gaagtctggc tggacgctac cgctgctcct accagaacgg aagcctctgg301 tccctgccca gcgaccagct ggagctcgtt gccacgggag tttttgccaa accctcgctc361 tcagcccagc ccggcccggc ggtgtcgtca ggaggggacg taaccctaca gtgtcagact421 cggtatggct ttgaccaatt tgctctgtac aaggaagggg accctgcgcc ctacaagaat481 cccgagagat ggtaccgggc tagtttcccc atcatcacgg tgaccgccgc ccacagcgga541 acctaccgat gctacagctt ctccagcagg gacccatacc tgtggtcggc ccccagcgac601 cccctggagc ttgtggtcac aggaacctct gtgaccccca gccggttacc aacagaacca661 ccttcctcgg tagcagaatt ctcagaagcc accgctgaac tgaccgtctc attcacaaac721 aaagtcttca caactgagac ttctaggagt atcaccacca gtccaaagga gtcagactct781 ccagctggtc ctgcccgcca gtactacacc aagggcaacc tggtccggat atgcctcggg841 gctgtgatcc taataatcct ggcggggttt ctggcagagg actggcacag ccggaggaag901 cgcctgcggc acaggggcag ggctgtgcag aggccgcttc cgcccctgcc gcccctcccg961 cagacccgga aatcacacgg gggtcaggat ggaggccgac aggatgttca cagccgcggg1021 ttatgttcat gaccgctgaa ccccaggcac ggtcgtatcc aagggaggga tcatggcatg1081 ggaggcgact caatcactag t<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>39<211>1534<212>DNA<213>人類(Homo sapiens)<400>391 tcatgtgggg gcgactgctc ctgtggcccc tggtgctggg gttcagcctg tctggcggca61 cccagacccc cagcgtctac gacgagagcg ggagcaccgg aggtggtgat gacagcacgc121 cctcaatcct gcctgccccc cgcggctacc caggccaagt ctgtgccaat gacagtgaca181 ccctggagct cccggacagc tcacgggcac tgcttctggg ctgggtgccc accaggctgg241 tgcccgccct ctatgggctg gtcctggtgg tggggctgcc ggccaatggg ctggcgctgt301 gggtgctggc cacgcaggca cctcggctgc cctccaccat gctgctgatg aacctcgcga361 ctgctgacct cctgctggcc ctggcgctgc ccccgcggat cgcctaccac ctgcgtggcc421 agcgctggcc cttcggggag gccgcctgcc gcctggccac ggccgcactc tatggtcaca481 tgtatggctc agtgctgctg ctggccgccg tcagcctgga tcgctacctg gccctggtgc541 acccgctgcg ggcccgcgcc ctgcgtggcc ggcgcctggc ccttggactc tgcatggctg601 cttggctcat ggcggccgcc ctggcactgc ccctgacact gcagcggcag accttccggc661 tggcgcgctc cgatcgcgtg ctctgccatg acgcgctgcc cctggacgca caggcctccc721 actggcaacc ggccttcacc tgcctggcgc tgttgggctg tttcctgccc ctgctggcca781 tgctgctgtg ctacggggcc accctgcaca cgctggcggc cagcggccgg cgctacggcc841 acgcgctgag gctgaccgca gtggtgctgg cctccgccgt ggccttcttc gtgcccagca901 acctgctgct gctgctgcat tactcggacc cgagccccag cgcctggggc aacctctatg961 gtgcctacgt gcccagcctg gcgctgagca ccctcaacag ctgcgtggat cccttcatct1021 actactacgt gtcggccgag ttcagggaca aggtgcgggc agggctcttc caacggtcgc1081 cgggggacac cgtggcctcc aaggcctctg cggaaggggg cagccggggc atgggcaccc1141 actcctcttt gctccagtga cacaaagtgg ggaaggctgt actgggtcga acagggtccc1201 ttcccccact tcacgtcctt cctgggacct cagaatgtga ccttatttgg aaatagggtt1261 gttacaactg tcactagcag aggtcacttt ggagaagggt gggccttaca tccagtgtgg1321 gtggtgtcct cataagataa ggagaggcca ggcctggtgg ctcacgcctg taatcccagc
1381 actttaagag gccaaggcgg atggatcact tgagcccagg agttcaacac cagcctgagc1441 aacatggtaa aaccccatct ctaccaaaaa tacaaaaatt agctgggctt ggtggctggc1501 gcctgtaatc ccagctactc angagactga ggca<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>40<211>504<212>DNA<213>人類(Homo sapiens)<400>401 ttcctgcaca gagagattca cgcaccctca agagtgtggg tgagacatat acagcctgtt61 agacctgaag gcagatggct cttcttaagg ccaataagga tctcatttcc gcaggattga121 aggagttcag cgttctgctg aatcagcagg tcttcaatga tcctctcgtc tctgaagaag181 acatggtgac tgtggtggag gactggatga acttctacat caactattac aggcagcagg241 tgacagggga gccccaagag cgagacaagg ctctgcagga gcttcggcaa gagctgaaca301 ctctggccaa ccctttcctg gccaagtaca gggacttcct gaagtctcat gagctcccga361 gtcacccacc gccctcctcc tagctcaggg acccagcccc tcctctctga gaaactctga421 ccttcatgtc cttaggctgt gctcctgcca ctctaccctg acacctcaat aaagaccagt481 gctggttttg ttggaaaaaa aaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>41<211>1312<212>DNA<213>人類(Homo sapiens)<400>411 gcggagcaag catcacacca tggcgtatga gtgttcctct gtgtagactc aacctgcgcc61 tcgccgtccc ccattcgcac acccgatgcc cgggggtcgc tacggactta aaatctccgc121 accgcaccct ccacctcaga aacgttcctg gatccgaaca ctgccccctg acgacctaga181 gagatcccgg ctcccagccc actgagtggc ttcagcctcg ctgccccccg cccacttcat241 ccctcaggca cctcccaact cctggcctct ctgcacgagg cgcctgcccc gggccccgcc301 tacaggggac ccagctcttc ttgcagccac tggaagctga tcacctggag tgaagacctc361 acacgaagaa gtctggaaga agaggaagag gaaagaaaag gagtcaggga tggcccttac421 tcaggtacgg ttgacattta gggatgtggc catagaattc tctcaggagg agtggaaatg481 cctggaccct gctcagagga tcttatacag ggacgtgatg ttggagaact actggaacct541 tgtttctctg ggactgtgtc attttgatat gaatattatc tccatgttgg aggaagggaa601 agagccctgg actgtgaaga gctgtgtgaa aatagcaaga aaaccaagaa cgccggaatg661 tgtcaaaggc gtggtcacag acctgctcag gagatggaaa cattggctgc tgctccttgg721 catctgctgc cccaaacctc atggaagagt ctccagccgt ctccgcctgt cgaggtccct781 cggccatttc ttccattctg cttttgccac tttcatgggg gtgtgtgata agcgagtggg841 ttctatcttc taagattgtt ctcagcataa ccgtaaagac acctaacaaa atccttctgt901 cattgatcct cagtcttaca tggggtgcgt attctgtttt tccaggcttc agcacagaaa961 tacaagtact gcatgttgtc acttacattt ggaatctaaa ccaataaaac taatagcagc1021 aaagagtaga atgtgggtta ccacaggttg gggactggag ggaataggga gatgttggtc
1081 actgggtgaa aacattagga gtaaatgata ggtttttgag atgacttata tggtaatagg1141 cttgtttcca tcagtccata ttgtatacct ataacagaat atcagtttgt ttcctgtaaa1201 tatatataac tataatttgt caatatagaa tttttttaaa aatcatattc cagttcttat1261 tgtgttggtt ctaaataaaa atgcttcttt ctcttaaaaa aaaaaaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>42<211>2225<212>DNA<213>人類(Homo sapiens)<400>421 ggtttttgag cccattactg ttggagctac agggagagaa acagaggagg agactgcaag61 agatcattgg aggccgtggg cacgctcttt actccatgtg tgggacattc attgcggaat121 aacatcggag gagaagtttc ccagagctat ggggacttcc catccggcgt tcctggtctt181 aggctgtctt ctcacagggc tgagcctaat cctctgccag ctttcattac cctctatcct241 tccaaatgaa aatgaaaagg ttgtgcagct gaattcatcc ttttctctga gatgctttgg301 ggagagtgaa gtgagctggc agtaccccat gtctgaagaa gagagctccg atgtggaaat361 cagaaatgaa gaaaacaaca gcggcctttt tgtgacggtc ttggaagtga gcagtgcctc421 ggcggcccac acagggttgt acacttgcta ttacaaccac actcagacag aagagaatga481 gcttgaaggc aggcacattt acatctatgt gccagaccca gatgtagcct ttgtacctct541 aggaatgacg gattatttag tcatcgtgga ggatgatgat tctgccatta taccttgtcg601 cacaactgat cccgagactc ctgtaacctt acacaacagt gagggggtgg tacctgcctc661 ctacgacagc agacagggct ttaatgggac cttcactgta gggccctata tctgtgaggc721 caccgtcaaa ggaaagaagt tccagaccat cccatttaat gtttatgctt taaaaggtac781 ttgtatcatc tccttccttc tttaaataag agtaacaggc aaaatcataa ggtgcgtgta841 ggattttttt ttttttttaa atcatcatca ctggtgatcc taaattctga tttggggatt901 taggacccca gctaatacaa tgtctgtggc tataataata agcttaaaat tactaaaggc961 caaagcttga ttacccatgc aagatttcat gtttcatcag ttgacttcaa aatactgtaa1021 ggaattcttt tcttacataa gcctcttact ttcattcaca ttcctgacta tggcggccct1081 aaaaacaaac atacacccag ggggttagat gcctagatta attttagtaa cttaagaaaa1141 gtgatttgaa gaaagtagtt tagacttcaa ccctttgatg tccacagtta gtacgcttgg1201 ggaagtataa tacatgctga ggtcaacaga tatttcctga acactatatt acatggagga1261 atgggtagca gcaagagtac actgttttaa aatcagagca cagctaattt tgtgccaggc1321 actgtgctag gttctgggaa agtactgaga ataactgagg agcagagtgg aagagaagaa1381 gagaagaaac aattggatag aaacaaagtg tctagagcag tgtggatcag caaatgttgg1441 ttgattaaat gaataaattt attagtcaag gagattgtgg acgagtataa ccataactaa1501 cccactgctg aggaatgcgg tgttctgttt gattggaatt tatttttatt gttattattt1561 tgtaattctg tattataact atatgcctaa ttgttgtaca ccatctcaca atcaagcctt1621 gtgagatttt ccaaatttta tcttgatcaa actggtttgc aaattatttt tcagggtttt1681 cttaaaaaaa aaaaaaaaaa cccaaacttt ataagatcct ggctatcctg tggattttta1741 ggcccttgta tttgttcttt tttatagcaa catcagagct ggatctagaa atggaagctc1801 ttaaaaccgt gtataagtca ggggaaacga ttgtggtcac ctgtgctgtt tttaacaatg1861 aggtggttga ccttcaatgg acttaccctg gagaagtggt aggtaccctc aaaacgtgca1921 atggcttgga gcagagcaac agggctcaga agacctgcat ttgagctcgg tctgtcactg1981 atgggcacat cactgagttt ctctagacct tagcttccca cctctgggat gaacacattt2041 gattaaatgg cctttaggac tccttgatca atgggagagt ttgaaatgat agttcctgga
2101 ccaggccctt cagaatacat aaagagtgtg ccgtaagcct tctttttcag aaggcagaca2161 gaaataggaa ggttctctgg ctacaagata tcaaccaaaa aaaaaaaaaa aaaaaaaaaa2221 aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>43<211>1108<212>DNA<213>人類(Homo sapiens)<400>431 aacagacagc agcgacttta ggctggataa tagtcaaatt cttacctcgc tctttcactg61 ctagtaagat cagattgcgt tctttcagtt actcttcaat cgccagtttc ttgatctgct121 tctaaaagaa gaagtagaga agataaatcc tgtcttcaat acctggaagg aaaaacaaaa181 taacctcaac tccgttttga aaaaaacatt ccaagaactt tcatcagaga ttttacttag241 atgatttaca caatgaagaa agtacatgca ctttgggctt ctgtatgcct gctgcttaat301 cttgcccctg cccctcttaa tgctgattct gaggaagatg aagaacacac aattatcaca361 gatacggagt tgccaccact gaaacttatg cattcatttt gtgcattcaa ggcggatgat421 ggcccatgta aagcaatcat gaaaagattt ttcttcaata ttttcactcg acagtgcgaa481 gaatttatat atgggggatg tgaaggaaat cagaatcgat ttgaaagtct ggaagagtgc541 aaaaaaatgt gtacaagaga taatgcaaac aggattataa agacaacatt gcaacaagaa601 aagccagatt tctgcttttt ggaagaagat cctggaatat gtcgaggtta tattaccagg661 tatttttata acaatcagac aaaacagtgt gaacgtttca agtatggtgg atgcctgggc721 aatatgaaca attttgagac actggaagaa tgcaagaaca tttgtgaaga tggtccgaat781 ggtttccagg tggataatta tggaacccag ctcaatgctg tgaataactc cctgactccg841 caatcaacca aggttcccag cctttttgtt acaaaagaag gaacaaatga tggttggaag901 aatgcggctc atatttacca agtctttctg aacgccttct gcattcatgc atccatgttc961 tttctaggat tggatagcat ttcatgccta tgttaatatt tgtgcttttg gcatttcctt1021 aatatttata tgtatacgtg atgcctttga tagcatactg ctaataaagt tttaatattt1081 acatgcaaaa aaaaaaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>44<211>612<212>DNA<213>人類(Homo sapiens)<400>441 acactcgctt ctggaacgtc tgaggttatc aataagctcc tagtccagac gccatgggtc61 atttcacaga ggaggacaag gctactatca caagcctgtg gggcaaggtg aatgtggaag121 atgctggagg agaaaccctg ggaaggctcc tggttgtcta cccatggacc cagaggttct181 ttgacagctt tggcaacctg tcctctgcct ctgccatcat gggcaacccc aaagtcaagg241 cacatggcaa gaaggtgctg acttccttgg gagatgccat aaagcacctg gatgatctca301 agggcacctt tgcccagctg agtgaactgc actgtgacaa gctgcatgtg gatcctgaga361 acttcaagct cctgggaaat gtgctggtga ccgttttggc aatccatttc ggcaaagaat421 tcacccctga ggtgcaggct tcctggcaga agatggtgac tgcagtggcc agtgccctgt
481 cctccagata ccactgagcc tcttgcccat gattcagagc tttcaaggat aggctttatt541 ctgcaagcaa tacaaataat aaatctattc tgctgagaga tcaaaaaaaa aaaaaaaaaa601 aaaaaaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>45<211>2557<212>DNA<213>人類(Homo sapiens)<400>451 gccgagccca gctccccgcg gcggccgcta gcccccggcc ccgagccacc actccgacct61 agcggccgcc gcccccggtg cgggatgagg agatccgcgg ccgccactgg gccccatgga121 ggagccgcag ccgccccgcc caccagcgag catggcctta ctgggcagcc agcactccgg181 cgccccctcc gcggccggcc cacctggcgg gacttcctcc gcggccacgg cggccgtgct241 ctccttcagc accgtggcga ccgcggcgct ggggaacctg agcgacgcaa gcggaggcgg301 cacagctgcc gctcccggtg gcggcggcct tggcgggtcc ggggcagcgc gggaggcggg361 ggcggcggtg aggcggccgc taggcccgga ggcggcgccg ctgctgtcgc acggagctgc421 agtggcggcc caggcgctcg tcctcctgct catcttcctg ctgtctagcc ttggcaactg481 cgcggtgatg ggggtgattg tgaagcaccg gcagctccgc accgtcacca acgccttcat541 cctgtcgctg tccctatcgg atctgctcac ggcgctgctc tgcctgcccg ccgccttcct601 ggacctcttc actccgcccg ggggttcggc gcctgccgcc gccgcggggc cctggcgcgg661 cttctgcgcc gccagccgct tcttcagctc gtgcttcggc atcgtgtcca cgctcagcgt721 ggcgctcatc tcgttggacc gttactgcgc tatcgtgcgg ccgccgcggg agaagatcgg781 ccgccgccgc gcgctgcagc tgctggcggg cgcctggctg acggccctgg gcttctcctt841 gccctgggag ctgctcgggg cgccccggga actcgcggcg gcgcagagct tccacggctg901 cctctaccgg acctccccgg accccgcgca gctgggcgcg gccttcagcg tggggctggt961 ggtggcctgc tacctgctgc ccttcctgct catgtgcttc tgccactacc acatctgcaa1021 gacggtgcgc ctgtcggacg tgcgcgtgcg gccggtgaac acctacgcgc gcgtgctgcg1081 cttcttcagc gaggtgcgca cggccaccac cgtcctcatc atgatcgtct tcgtcatctg1141 ctgctggggg ccctactgct tcctggtgct gctggccgcc gcccggcagg cccagaccat1201 gcaggccccc tcgctcctca gcgtggtggc cgtctggctg acctgggcca atggggccat1261 caaccctgtc atctacgcca tccgcaatcc caacatttcg atgctcctag ggcgcaaccg1321 cgaggagggc taccggacta ggaatgtgga cgctttcctg cccagccagg gcccgggtct1381 gcaagccaga agccgcagtc gccttcgaaa ccgctatgcc aaccggctgg gggcctgcaa1441 caggatgtcc tcttccaacc cggccagcgg agtggcaggg gacgtggcca tgtgggcccg1501 caaaaatcca gttgtacttt tctgccgaga gggaccacca gagccggtga cggcagtgac1561 caaacagcct aaatccgaag ctggggatac cagcctctaa gacggttgga atggccagct1621 tatgaaggca aatttccact cgcattattt aatgatggaa gattctgggg gagagttgtg1681 gatttcataa agccaaacat ttaaagctag agacggggga ggcttaccac tttccccaaa1741 caacataaaa gacaatgtcc cttcttcaaa agtgccaaaa ggaatgtaaa atgcaaaaat1801 taaaacaatc ttaaaccaca taaccaagca ttgtgaactg ctatccaact atttagtggt1861 agaactagga tttgaactgc agtctgtttg gcctcagaac tccatgtttg tttctctcta1921 tccccacaga agtctacagg gcaacttcct gggagctaag gctactaaaa ggtagaagcc1981 acagtactca tctgcagagg gcttacagcc tcagcaagga ccttgtggct ttgtaacaac2041 aatcagccat aacaagttta cttgtggaaa agaaaaggtg tagcactttc agaagaggct2101 atcaaagaaa agagatgaac ttggaagcaa gagatacgca gctcagcatg acagagactc
2161 cattccaggt ggaaaaagca catggctctt tcttctccga gatcccagga ctatcttatt2221 ttcctcagag gggcaggtta caagaacttc acatctctca ggctacatgt tgcaaaggtt2281 aaattccagg ttgtacgatt tttcacttcc accatcaagt tatgagtgtg attgtttccc2341 tgcagttttg ccaatagagt gattttagac tatttacatc gtgggttaca accaatgtca2401 gttattctgg ggaaacccaa ctgccatgtt gtgaggacac tcaagcagcc ctatggagga2461 gcccacatgg tgagtgaata actacaagct gactctaatt ttaaaaaata aaaattttat2521 ctctcaccaa ttttaaaatg acaaaaaaaa aaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>46<211>2475<212>DNA<213>人類(Homo sapiens)<400>461 agccgctctc cgcatcccag gacagcggtg cggccctcgg ccggggcgcc cactccgcag61 cacccagcga gcgagcgagc gagcgagggc ggccgacgcg cccggccggg acccagctgc121 ccgtatgacc gcgccgggcg ccgccgggcg ctgccctccc acgacatggc tgggctccct181 gctgttgttg gtctgtctcc tggcgagcag gagtatcacc gaggaggtgt cggagtactg241 tagccacatg attgggagtg gacacctgca gtctctgcag cggctgattg acagtcagat301 ggagacctcg tgccaaatta catttgagtt tgtagaccag gaacagttga aagatccagt361 gtgctacctt aagaaggcat ttctcctggt acaagacata atggaggaca ccatgcgctt421 cagagataac acccccaatg ccatcgccat tgtgcagctg caggaactct ctttgaggct481 gaagagctgc ttcaccaagg attatgaaga gcatgacaag gcctgcgtcc gaactttcta541 tgagacacct ctccagttgc tggagaaggt caagaatgtc tttaatgaaa caaagaatct601 ccttgacaag gactggaata ttttcagcaa gaactgcaac aacagctttg ctgaatgctc661 cagccaagat gtggtgacca agcctgattg caactgcctg taccccaaag ccatccctag721 cagtgacccg gcctctgtct cccctcatca gcccctcgcc ccctccatgg cccctgtggc781 tggcttgacc tgggaggact ctgagggaac tgagggcagc tccctcttgc ctggtgagca841 gcccctgcac acagtggatc caggcagtgc caagcagcgg ccacccagga gcacctgcca901 gagctttgag ccgccagaga ccccagttgt caaggacagc accatcggtg gctcaccaca961 gcctcgcccc tctgtcgggg ccttcaaccc cgggatggag gatattcttg actctgcaat1021 gggcactaat tgggtcccag aagaagcctc tggagaggcc agtgagattc ccgtacccca1081 agggacagag ctttccccct ccaggccagg agggggcagc atgcagacag agcccgccag1141 acccagcaac ttcctctcag catcttctcc actccctgca tcagcaaagg gccaacagcc1201 ggcagatgta actggtaccg ccttgcccag ggtgggcccc gtgaggccca ctggccagga1261 ctggaatcac accccccaga agacagacca tccatctgcc ctgctcagag accccccgga1321 gccaggctct cccaggatct catcaccgcg cccccagggc ctcagcaacc cctccaccct1381 ctctgctcag ccacagcttt ccagaagcca ctcctcgggc agcgtgctgc cccttgggga1441 gctggagggc aggaggagca ccagggatcg gaggagcccc gcagagccag aaggaggacc1501 agcaagtgaa ggggcagcca ggcccctgcc ccgttttaac tccgttcctt tgactgacac1561 acatgagagg cagtccgagg gatcctccag cccgcagctc caggagtctg tcttccacct1621 gctggtgccc agtgtcatcc tggtcttgct ggccgtcgga ggcctcttgt tctacaggtg1681 gaggcggcgg agccatcaag agcctcagag agcggattct cccttggagc aaccagaggg1741 cagccccctc actcaggatg acagacaggt ggaactgcca gtgtagaggg aattctaaga1801 cccctcacca tcctggacac tctcgtttgt caatgtccct ctgaaaatgt gacgcccagc1861 cccggacaca gtactccaga tgttgtctga ccagctcaga gagagtacag tgggactgtt
1921 accttccttg atatggacag tattcttcta tttgtgcaga ttaagattgc attagttcct1981 ttcttaacaa ctgcatcata ctgttgtcat atgttgagcc tgtggtctat aaaaccccca2041 gttccatttc ccataaactt ctgtcaagcc agaccatctc taccctgtac ttggacaact2101 taactttttt aaccaaagtg cagtttatgt tcacctttgt taaagccagc ttgtggtttc2161 tgcccatcac ctgaacctac tgaagttgtg tgaaatccta attctgtcat ctccgtagcc2221 ctcccagttg tgcctcctgc acattgatga gtgcctgctg ttgtctttgc ccatgttgtt2281 gatgtagctg tgaccctatt gttcctcacc cctgcccccc gccaacccca gctggcccac2341 ctcttccccc tcccacccaa gcccacagcc agcccatcag gaagccttcc tggcttctcc2401 acaaccttct gactgtcttt tcagtcatgc cccctgctct tttgtatttg gctaatagta2461 tatcaatttg cactt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>47<211>1983<212>DNA<213>人類(Homo sapiens)<400>471 gaggactgca gtgtaggact ttcctgcaga ataccatttg atcctattaa gaattgtcca61 aatgttggag catttgattg aaaaatcctt cttagccatt ttaaagatag ctttccaatg121 attagacgaa ttgattcttt ctgtgactca tcagttcatt tcctgtaaaa ttcatgtctt181 gctgttgatt tgtgaataag aaccagagct tgtagaaacc actttaatca tatcgaggag241 tttgcaagaa acaggtgctt aacactaatt cacctcctga acaagaaaaa tgggctgtga301 ccggaactgt gggctcatcg ctggggctgt cattggtgct gtcctggctg tgtttggagg361 tattctaatg ccagttggag acctgcttat ccagaagaca attaaaaagc aagttgtcct421 cgaagaaggt acaattgctt ttaaaaattg ggttaaaaca ggcacagaag tttacagaca481 gttttggatc tttgatgtgc aaaatccaca ggaagtgatg atgaacagca gcaacattca541 agttaagcaa agaggtcctt atacgtacag agttcgtttt ctagccaagg aaaatgtaac601 ccaggacgct gaggacaaca cagtctcttt cctgcagccc aatggtgcca tcttcgaacc661 ttcactatca gttggaacag aggctgacaa cttcacagtt ctcaatctgg ctgtggcagc721 tgcatcccat atctatcaaa atcaatttgt tcaaatgatc ctcaattcac ttattaacaa781 gtcaaaatct tctatgttcc aagtcagaac tttgagagaa ctgttatggg gctataggga841 tccatttttg agtttggttc cgtaccctgt tactaccaca gttggtctgt tttatcctta901 caacaatact gcagatggag tttataaagt tttcaatgga aaagataaca taagtaaagt961 tgccataatc gacacatata aaggtaaaag gaatctgtcc tattgggaaa gtcactgcga1021 catgattaat ggtacagatg cagcctcatt tccacctttt gttgagaaaa gccaggtatt1081 gcagttcttt tcttctgata tttgcaggtc aatctatgct gtatttgaat ccgacgttaa1141 tctgaaagga atccctgtgt atagatttgt tcttccatcc aaggcctttg cctctccagt1201 tgaaaaccca gacaactatt gtttctgcac agaaaaaatt atctcaaaaa attgtacatc1261 atatggtgtg ctagacatca gcaaatgcaa agaagggaga cctgtgtaca tttcacttcc1321 tcattttctg tatgcaagtc ctgatgtttc agaacctatt gatggattaa acccaaatga1381 agaagaacat aggacatact tggatattga acctataact ggattcactt tacaatttgc1441 aaaacggctg caggtcaacc tattggtcaa gccatcagaa taaattcaag tattaaagaa1501 tctgaagagg aactatattg tgcctattct ttggcttaat gagactggga ccattggtga1561 tgagaaggca aacatgttca gaagtcaagt aactggaaaa ataaacctcc ttggcctgat1621 agaaatgatc ttactcagtg ttggtgtggt gatgtttgtt gcttttatga tttcatattg1681 tgcatgcaga tcgaaaacaa taaaataagt aagtatgtac caaaaaatat tgcttcaata
1741 atattagctt atatattact tgttttcact ttatcaaaga gaagttacat attaggccat1801 atatatttct agacatgtct agccactgat catttttaaa tataggtaaa taaacctata1861 aatattatca cgcagatcac taaagtatat ctttaattct gggagaaatg agataaaaga1921 tgtacttgtg accattgtaa caatagcaca aataaagcac ttgtgccaaa gttgtccaaa1981 aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>48<211>2217<212>DNA<213>人類(Homo sapiens)<400>481 tgctgtactg agagagaatg ttacataaca ttgagaacta gtacaagtaa atattaaagt61 gaagtgacca tttcctacac aagctcattc agaggaggat gaagaccatt ttggaggaag121 aaaagcaccc ttattaagaa ttgcagcaag taagccaaca aggtcttttc aggatgattt181 tcttatatca agtggtacat ttcattttat ttacttcagt ttctggtgaa tgtgtgactc241 agttgttgaa ggacacctgc tttgaaggag gggacattac tacggtcttc acaccaagcg301 ccaagtactg ccaggtagtc tgcacttacc acccaagatg tttactcttc actttcacgg361 cggaatcacc atctgaggat cccacccgat ggtttacttg tgtcctgaaa gacagtgtta421 cagaaacact gccaagagtg aataggacag cagcgatttc tgggtattct ttcaagcaat481 gctcacacca aataagcgct tgcaacaaag acatttatgt ggacctagac atgaagggca541 taaactataa cagctcagtt gccaagagtg ctcaagaatg ccaagaaaga tgcacggatg601 acgtccactg ccactttttc acgtacgcca caaggcagtt tcccagcctg gagcatcgta661 acatttgtct actgaagcac acccaaacag ggacaccaac cagaataacg aagctcgata721 aagtggtgtc tggattttca ctgaaatcct gtgcactttc taatctggct tgtattaggg781 acattttccc taatacggtg tttgcagaca gcaacatcga cagtgtcatg gctcccgatg841 cttttgtctg tggccgaatc tgcactcatc atcccggttg cttgtttttt accttctttt901 cccaggaatg gcccaaagaa tctcaaagaa atctttgtct ccttaaaaca tctgagagtg961 gattgcccag tacacgcatt aaaaagagca aagctctttc tggtttcagt ctacaaagct1021 gcaggcacag catcccagtg ttctgccatt cttcatttta ccatgacact gatttcttgg1081 gagaagaact ggatattgtt gctgcaaaaa gtcacgaggc ctgccagaaa ctgtgcacca1141 atgccgtccg ctgccagttt tttacctata ccccagccca agcatcctgc aacgaaggga1201 agggcaagtg ttacttaaag ctttcttcaa acggatctcc aactaaaata cttcacggga1261 gaggaggcat ctctggatac acattaaggt tgtgtaaaat ggataatgag tgtaccacca1321 aaatcaagcc caggatcgtt ggaggaactg cgtctgttcg tggtgagtgg ccgtggcagg1381 tgaccctgca cacaacctca cccactcaga gacacctgtg tggaggctcc atcattggaa1441 accagtggat attaacagcc gctcactgtt tctatggggt agagtcacct aagattttgc1501 gtgtctacag tggcatttta aatcaatctg aaataaaaga ggacacatct ttctttgggg1561 ttcaagaaat aataatccat gatcagtata aaatggcaga aagcgggtat gatattgcct1621 tgttgaaact ggaaaccaca gtgaattaca cagattctca acgacccata tgcctgcctt1681 ccaaaggaga tagaaatgta atatacactg attgctgggt gactggatgg gggtacagaa1741 aactaagaga caaaatacaa aatactctcc agaaagccaa gataccctta gtgaccaacg1801 aagagtgcca gaagagatac agaggacata aaataaccca taagatgatc tgtgccggct1861 acagggaagg agggaaggac gcttgcaagg gagattcggg aggccctctg tcctgcaaac1921 acaatgaggt ctggcatctg gtaggcatca cgagctgggg cgaaggctgt gctcaaaggg1981 agcggccagg tgtttacacc aacgtggtcg agtacgtgga ctggattctg gagaaaactc
2041 aagcagtgtg aatgggttcc caggggccat tggagtccct gaaggaccca ggatttgctg2101 ggagagggtg ttgagttcac tgtgccagca tgcttcctcc acagtaacac gctgaagggg2161 cttggtgttt gtaagaaaat gctagaagaa aacaaactgt cacaagttgt tatgtcc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>49<211>6914<212>DNA<213>人類(Homo sapiens)<400>491 tcattgcagc tgggacagcc cggagtgtgg ttagcagctc ggcaagcgct gcccaggtcc61 tggggtggtg gcagccagcg ggagcaggaa aggaagcatg ttcccaggct gcccacgcct121 ctgggtcctg gtggtcttgg gcaccagctg ggtaggctgg gggagccaag ggacagaagc181 ggcacagcta aggcagttct acgtggctgc tcagggcatc agttggagct accgacctga241 gcccacaaac tcaagtttga atctttctgt aacttccttt aagaaaattg tctacagaga301 gtatgaacca tattttaaga aagaaaaacc acaatctacc atttcaggac ttcttgggcc361 tactttatat gctgaagtcg gagacatcat aaaagttcac tttaaaaata aggcagataa421 gcccttgagc atccatcctc aaggaattag gtacagtaaa ttatcagaag gtgcttctta481 ccttgaccac acattccctg cagagaagat ggacgacgct gtggctccag gccgagaata541 cacctatgaa tggagtatca gtgaggacag tggacccacc catgatgacc ctccatgcct601 cacacacatc tattactccc atgaaaatct gatcgaggat ttcaactctg ggctgattgg661 gcccctgctt atctgtaaaa aagggaccct aactgagggt gggacacaga agacgtttga721 caagcaaatc gtgctactat ttgctgtgtt tgatgaaagc aagagctgga gccagtcatc781 atccctaatg tacacagtca atggatatgt gaatgggaca atgccagata taacagtttg841 tgcccatgac cacatcagct ggcatctgct gggaatgagc tcggggccag aattattctc901 cattcatttc aacggccagg tcctggagca gaaccatcat aaggtctcag ccatcaccct961 tgtcagtgct acatccacta ccgcaaatat gactgtgggc ccagagggaa agtggatcat1021 atcttctctc accccaaaac atttgcaagc tgggatgcag gcttacattg acattaaaaa1081 ctgcccaaag aaaaccagga atcttaagaa aataactcgt gagcagaggc ggcacatgaa1141 gaggtgggaa tacttcattg ctgcagagga agtcatttgg gactatgcac ctgtaatacc1201 agcgaatatg gacaaaaaat acaggtctca gcatttggat aatttctcaa accaaattgg1261 aaaacattat aagaaagtta tgtacacaca gtacgaagat gagtccttca ccaaacatac1321 agtgaatccc aatatgaaag aagatgggat tttgggtcct attatcagag cccaggtcag1381 agacacactc aaaatcgtgt tcaaaaatat ggccagccgc ccctatagca tttaccctca1441 tggagtgacc ttctcgcctt atgaagatga agtcaactct tctttcacct caggcaggaa1501 caacaccatg atcagagcag ttcaaccagg ggaaacctat acttataagt ggaacatctt1561 agagtttgat gaacccacag aaaatgatgc ccagtgctta acaagaccat actacagtga1621 cgtggacatc atgagagaca tcgcctctgg gctaatagga ctacttctaa tctgtaagag1681 cagatccctg gacaggcgag gaatacagag ggcagcagac atcgaacagc aggctgtgtt1741 tgctgtgttt gatgagaaca aaagctggta ccttgaggac aacatcaaca agttttgtga1801 aaatcctgat gaggtgaaac gtgatgaccc caagttttat gaatcaaaca tcatgagcac1861 tatcaatggc tatgtgcctg agagcataac tactcttgga ttctgctttg atgacactgt1921 ccagtggcac ttctgtagtg tggggaccca gaatgaaatt ttgaccatcc acttcactgg1981 gcactcattc atctatggaa agaggcatga ggacaccttg accctcttcc ccatgcgtgg2041 agaatctgtg acggtcacaa tggataatgt tggaacttgg atgttaactt ccatgaattc2101 tagtccaaga agcaaaaagc tgaggctgaa attcagggat gttaaatgta tcccagatga
2161 tgatgaagac tcatatgaga tttttgaacc tccagaatct acagtcatgg ctacacggaa2221 aatgcatgat cgtttagaac ctgaagatga agagagtgat gctgactatg attaccagaa2281 cagactggct gcagcattag gaattaggtc attccgaaac tcatcattga accaggaaga2341 agaagagttc aatcttactg ccctagctct ggagaatggc actgaattcg tttcttcgaa2401 cacagatata attgttggtt caaattattc ttccccaagt aatattagta agttcactgt2461 caataacctt gcagaacctc agaaagcccc ttctcaccaa caagccacca cagctggttc2521 cccactgaga cacctcattg gcaagaactc agttctcaat tcttccacag cagagcattc2581 cagcccatat tctgaagacc ctatagagga tcctctacag ccagatgtca cagggatacg2641 tctactttca cttggtgctg gagaattcag aagtcaagaa catgctaagc gtaagggacc2701 caaggtagaa agagatcaag cagcaaagca caggttctcc tggatgaaat tactagcaca2761 taaagttggg agacacctaa gccaagacac tggttctcct tccggaatga ggccctggga2821 ggaccttcct agccaagaca ctggttctcc ttccagaatg aggccctggg aggaccctcc2881 tagtgatctg ttactcttaa aacaaagtaa ctcatctaag attttggttg ggagatggca2941 tttggcttct gagaaaggta gctatgaaat aatccaagat actgatgaag acacagctgt3001 taacaattgg ctgatcagcc cccagaatgc ctcacgtgct tggggagaaa gcacccctct3061 tgccaacaag cctggaaagc agagtggcca cccaaagttt cctagagtta gacataaatc3121 tctacaagta agacaggatg gaggaaagag tagactgaag aaaagccagt ttctcattaa3181 gacacgaaaa aagaaaaaag agaagcacac acaccatgct cctttatctc cgaggacctt3241 tcaccctcta agaagtgaag cctacaacac attttcagaa agaagactta agcattcgtt3301 ggtgcttcat aaatccaatg aaacatctct tcccacagac ctcaatcaga cattgccctc3361 tatggatttt ggctggatag cctcacttcc tgaccataat cagaattcct caaatgacac3421 tggtcaggca agctgtcctc caggtcttta tcagacagtg cccccagagg aacactatca3481 aacattcccc attcaagacc ctgatcaaat gcactctact tcagacccca gtcacagatc3541 ctcttctcca gagctcagtg aaatgcttga gtatgaccga agtcacaagt ccttccccac3601 agatataagt caaatgtccc cttcctcaga acatgaagtc tggcagacag tcatctctcc3661 agacctcagc caggtgaccc tctctccaga actcagccag acaaacctct ctccagacct3721 cagccacacg actctctctc cagaactcat tcagagaaac ctttccccag ccctcggtca3781 gatgcccatt tctccagacc tcagccatac aaccctttct ccagacctca gccatacaac3841 cctttcttta gacctcagcc agacaaacct ctctccagaa ctcagtcaga caaacctttc3901 tccagccctc ggtcagatgc ccctttctcc agacctcagc catacaacca tttctctaga3961 cttcagccag acaaacctct ctccagaact cagccatatg actctctctc cagaactcag4021 tcagacaaac ctttccccag ccctcggtca gatgcccatt tctccagacc tcagccatac4081 aaccctttct ctagacttca gccagacaaa cctctctcca gaactcagtc aaacaaacct4141 ttccccagcc ctcggtcaga tgcccctttc tccagacccc agccatacaa ccctttctct4201 agacctcagc cagacaaacc tctctccaga actcagtcag acaaaccttt ccccagacct4261 cagtgagatg cccctctttg cagatctcag tcaaattccc cttaccccag acctcgacca4321 gatgacactt tctccagacc ttggtgagac agatctttcc ccaaactttg gtcagatgtc4381 cctttcccca gacctcagcc aggtgactct ctctccagac atcagtgaca ccacccttct4441 cccggatctc agccagatat cacctcctcc agaccttgat cagatattct acccttctga4501 atctagtcag tcattgcttc ttcaagaatt taatgagtct tttccttatc cagaccttgg4561 tcagatgcca tctccttcat ctcctactct caatgatact tttctatcaa aggaatttaa4621 tccactggtt atagtgggcc tcagtaaaga tggtacagat tacattgaga tcattccaaa4681 ggaagaggtc cagagcagtg aagatgacta tgctgaaatt gattatgtgc cctatgatga4741 cccctacaaa actgatgtta ggacaaacat caactcctcc agagatcctg acaacattgc4801 agcatggtac ctccgcagca acaatggaaa cagaagaaat tattacattg ctgctgaaga4861 aatatcctgg gattattcag aatttgtaca aagggaaaca gatattgaag actctgatga4921 tattccagaa gataccacat ataagaaagt agtttttcga aagtacctcg acagcacttt4981 taccaaacgt gatcctcgag gggagtatga agagcatctc ggaattcttg gtcctattat
5041 cagagctgaa gtggatgatg ttatccaagt tcgttttaaa aatttagcat ccagaccgta5101 ttctctacat gcccatggac tttcctatga aaaatcatca gagggaaaga cttatgaaga5161 tgactctcct gaatggttta aggaagataa tgctgttcag ccaaatagca gttataccta5221 cgtatggcat gccactgagc gatcagggcc agaaagtcct ggctctgcct gtcgggcttg5281 ggcctactac tcagctgtga acccagaaaa agatattcac tcaggcttga taggtcccct5341 cctaatctgc caaaaaggaa tactacataa ggacagcaac atgcctgtgg acatgagaga5401 atttgtctta ctatttatga cctttgatga aaagaagagc tggtactatg aaaagaagtc5461 ccgaagttct tggagactca catcctcaga aatgaaaaaa tcccatgagt ttcacgccat5521 taatgggatg atctacagct tgcctggcct gaaaatgtat gagcaagagt gggtgaggtt5581 acacctgctg aacataggcg gctcccaaga cattcacgtg gttcactttc acggccagac5641 cttgctggaa aatggcaata aacagcacca gttaggggtc tggccccttc tgcctggttc5701 atttaaaact cttgaaatga aggcatcaaa acctggctgg tggctcctaa acacagaggt5761 tggagaaaac cagagagcag ggatgcaaac gccatttctt atcatggaca gagactgtag5821 gatgccaatg ggactaagca ctggtatcat atctgattca cagatcaagg cttcagagtt5881 tctgggttac tgggagccca gattagcaag attaaacaat ggtggatctt ataatgcttg5941 gagtgtagaa aaacttgcag cagaatttgc ctctaaacct tggatccagg tggacatgca6001 aaaggaagtc ataatcacag ggatccagac ccaaggtgcc aaacactacc tgaagtcctg6061 ctataccaca gagttctatg tagcttacag ttccaaccag atcaactggc agatcttcaa6121 agggaacagc acaaggaatg tgatgtattt taatggcaat tcagatgcct ctacaataaa6181 agagaatcag tttgacccac ctattgtggc tagatatatt aggatctctc caactcgagc6241 ctataacaga cctacccttc gattggaact gcaaggttgt gaggtaaatg gatgttccac6301 acccctgggt atggaaaatg gaaagataga aaacaagcaa atcacagctt cttcgtttaa6361 gaaatcttgg tggggagatt actgggaacc cttccgtgcc cgtctgaatg cccagggacg6421 tgtgaatgcc tggcaagcca aggcaaacaa caataagcag tggctagaaa ttgatctact6481 caagatcaag aagataacgg caattataac acagggctgc aagtctctgt cctctgaaat6541 gtatgtaaag agctatacca tccactacag tgagcaggga gtggaatgga aaccatacag6601 gctgaaatcc tccatggtgg acaagatttt tgaaggaaat actaatacca aaggacatgt6661 gaagaacttt ttcaaccccc caatcatttc caggtttatc cgtgtcattc ctaaaacatg6721 gaatcaaagt attgcacttc gcctggaact ctttggctgt gatatttact agaattgaac6781 attcaaaaac ccctggaaga gactctttaa gacctcaaac catttagaat gggcaatgta6841 ttttacgctg tgttaaatgt taacagtttt ccactatttc tctttctttt ctattagtga6901 ataaaatttt atac<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>50<211>2478<212>DNA<213>人類(Homo sapiens)<400>501 agtcccatgg ggaatgtcaa caggcagggg cagcactgca gagatttcat catggtctcc61 caggccctca ggctcctctg ccttctgctt gggcttcagg gctgcctggc tgcaggcggg121 gtcgctaagg cctcaggagg agaaacacgg gacatgccgt ggaagccggg gcctcacaga181 gtcttcgtaa cccaggagga agcccacggc gtcctgcacc ggcgccggcg cgccaacgcg241 ttcctggagg agctgcggcc gggctccctg gagagggagt gcaaggagga gcagtgctcc301 ttcgaggagg cccgggagat cttcaaggac gcggagagga cgaagctgtt ctggatttct361 tacagtgatg gggaccagtg tgcctcaagt ccatgccaga atgggggctc ctgcaaggac
421 cagctccagt cctatatctg cttctgcctc cctgccttcg agggccggaa ctgtgagacg481 cacaaggatg accagctgat ctgtgtgaac gagaacggcg gctgtgagca gtactgcagt541 gaccacacgg gcaccaagcg ctcctgtcgg tgccacgagg ggtactctct gctggcagac601 ggggtgtcct gcacacccac agttgaatat ccatgtggaa aaatacctat tctagaaaaa661 agaaatgcca gcaaacccca aggccgaatt gtggggggca aggtgtgccc caaaggggag721 tgtccatggc aggtcctgtt gttggtgaat ggagctcagt tgtgtggggg gaccctgatc781 aacaccatct gggtggtctc cgcggcccac tgtttcgaca aaatcaagaa ctggaggaac841 ctgatcgcgg tgctgggcga gcacgacctc agcgagcacg acggggatga gcagagccgg901 cgggtggcgc aggtcatcat ccccagcacg tacgtcccgg gcaccaccaa ccacgacatc961 gcgctgctcc gcctgcacca gcccgtggtc ctcactgacc atgtggtgcc cctctgcctg1021 cccgaacgga cgttctctga gaggacgctg gccttcgtgc gcttctcatt ggtcagcggc1081 tggggccagc tgctggaccg tggcgccacg gccctggagc tcatggtgct caacgtgccc1141 cggctgatga cccaggactg cctgcagcag tcacggaagg tgggagactc cccaaatatc1201 acggagtaca tgttctgtgc cggctactcg gatggcagca aggactcctg caagggggac1261 agtggaggcc cacatgccac ccactaccgg ggcacgtggt acctgacggg catcgtcagc1321 tggggccagg gctgcgcaac cgtgggccac tttggggtgt acaccagggt ctcccagtac1381 atcgagtggc tgcaaaagct catgcgctca gagccacgcc caggagtcct cctgcgagcc1441 ccatttccct agcccagcag ccctggcctg tggagagaaa gccaaggctg cgtcgaactg1501 tcctggcacc aaatcccata tattcttctg cagttaatgg ggtagaggag ggcatgggag1561 ggagggagag gtggggaggg agacagagac agaaacagag agagacagag acagagagag1621 actgagggag agactctgag gacatggaga gagactcaaa gagactccaa gattcaaaga1681 gactaataga gacacagaga tggaatagaa aagatgagag gcagaggcag acaggcgctg1741 gacagagggg caggggagtg ccaaggttgt cctggaggca gacagcccag ctgagcctcc1801 ttacctccct tcagccaagc cccacctgca cgtgatctgc tggccctcag gctgctgctc1861 tgccttcatt gctggagaca gtagaggcat gaacacacat ggatgcacac acacacacgc1921 caatgcacac acacagagat atgcacacac acggatgcac acacagatgg tcacacagag1981 atacgcaaac acaccgatgc acacgcacat agagatatgc acacacagat gcacacacag2041 atatacacat ggatgcacgc acatgccaat gcacgcacac atcagtgcac acggatgcac2101 agagatatgc acacaccgat gtgcgcacac acagatatgc acacacatgg atgagcacac2161 acacaccaag tgcgcacaca caccgatgta cacacacaga tgcacacaca gatgcacaca2221 caccgatgct gactccatgt gtgctgtcct ctgaaggcgg ttgtttagct ctcacttttc2281 tggttcttat ccattatcat cttcacttca gacaattcag aagcatcacc atgcatggtg2341 gcgaatgccc ccaaactctc ccccaaatgt atttctccct tcgctgggtg ccgggctgca2401 cagactattc cccacctgct tcccagcttc acaataaacg gctgcgtctc ctccgcacac2461 ctgtggtgcc tgccaccc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>51<211>2804<212>DNA<213>人類(Homo sapiens)<400>511 accactttca caatctgcta gcaaaggtta tgcagcgcgt gaacatgatc atggcagaat61 caccaggcct catcaccatc tgccttttag gatatctact cagtgctgaa tgtacagttt121 ttcttgatca tgaaaacgcc aacaaaattc tgaatcggcc aaagaggtat aattcaggta181 aattggaaga gtttgttcaa gggaaccttg agagagaatg tatggaagaa aagtgtagtt
241 ttgaagaagc acgagaagtt tttgaaaaca ctgaaagaac aactgaattt tggaagcagt301 atgttgatgg agatcagtgt gagtccaatc catgtttaaa tggcggcagt tgcaaggatg361 acattaattc ctatgaatgt tggtgtccct ttggatttga aggaaagaac tgtgaattag421 atgtaacatg taacattaag aatggcagat gcgagcagtt ttgtaaaaat agtgctgata481 acaaggtggt ttgctcctgt actgagggat atcgacttgc agaaaaccag aagtcctgtg541 aaccagcagt gccatttcca tgtggaagag tttctgtttc acaaacttct aagctcaccc601 gtgctgagac tgtttttcct gatgtggact atgtaaattc tactgaagct gaaaccattt661 tggataacat cactcaaagc acccaatcat ttaatgactt cactcgggtt gttggtggag721 aagatgccaa accaggtcaa ttcccttggc aggttgtttt gaatggtaaa gttgatgcat781 tctgtggagg ctctatcgtt aatgaaaaat ggattgtaac tgctgcccac tgtgttgaaa841 ctggtgttaa aattacagtt gtcgcaggtg aacataatat tgaggagaca gaacatacag901 agcaaaagcg aaatgtgatt cgaattattc ctcaccacaa ctacaatgca gctattaata961 agtacaacca tgacattgcc cttctggaac tggacgaacc cttagtgcta aacagctacg1021 ttacacctat ttgcattgct gacaaggaat acacgaacat cttcctcaaa tttggatctg1081 gctatgtaag tggctgggga agagtcttcc acaaagggag atcagcttta gttcttcagt1141 accttagagt tccacttgtt gaccgagcca catgtcttcg atctacaaag ttcaccatct1201 ataacaacat gttctgtgct ggcttccatg aaggaggtag agattcatgt caaggagata1261 gtgggggacc ccatgttact gaagtggaag ggaccagttt cttaactgga attattagct1321 ggggtgaaga gtgtgcaatg aaaggcaaat atggaatata taccaaggta tcccggtatg1381 tcaactggat taaggaaaaa acaaagctca cttaatgaaa gatggatttc caaggttaat1441 tcattggaat tgaaaattaa cagggcctct cactaactaa tcactttccc atcttttgtt1501 agatttgaat atatacattc tatgatcatt gctttttctc tttacagggg agaatttcat1561 attttacctg agcaaattga ttagaaaatg gaaccactag aggaatataa tgtgttagga1621 aattacagtc atttctaagg gcccagccct tgacaaaatt gtgaagttaa attctccact1681 ctgtccatca gatactatgg ttctccacta tggcaactaa ctcactcaat tttccctcct1741 tagcagcatt ccatcttccc gatcttcttt gcttctccaa ccaaaacatc aatgtttatt1801 agttctgtat acagtacagg atctttggtc tactctatca caaggccagt accacactca1861 tgaagaaaga acacaggagt agctgagagg ctaaaactca tcaaaaacac tactcctttt1921 cctctaccct attcctcaat cttttacctt ttccaaatcc caatccccaa atcagttttt1981 ctctttctta ctccctctct cccttttacc ctccatggtc gttaaaggag agatggggag2041 catcattctg ttatacttct gtacacagtt atacatgtct atcaaaccca gacttgcttc2101 catagtggag acttgctttt cagaacatag ggatgaagta aggtgcctga aaagtttggg2161 ggaaaagttt ctttcagaga gttaagttat tttatatata taatatatat ataaaatata2221 taatatacaa tataaatata tagtgtgtgt gtgtatgcgt gtgtgtagac acacacgcat2281 acacacatat aatggaagca ataagccatt ctaagagctt gtatggttat ggaggtctga2341 ctaggcatga tttcacgaag gcaagattgg catatcattg taactaaaaa agctgacatt2401 gacccagaca tattgtactc tttctaaaaa taataataat aatgctaaca gaaagaagag2461 aaccgttcgt ttgcaatcta cagctagtag agactttgag gaagaattca acagtgtgtc2521 ttcagcagtg ttcagagcca agcaagaagt tgaagttgcc tagaccagag gacataagta2581 tcatgtctcc tttaactagc ataccccgaa gtggagaagg gtgcagcagg ctcaaaggca2641 taagtcattc caatcagcca actaagttgt ccttttctgg tttcgtgttc accatggaac2701 attttgatta tagttaatcc ttctatcttg aatcttctag agagttgctg accaactgac2761 gtatgtttcc ctttgtgaat taataaactg gtgttctggt tcat<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>52
<211>2941<212>DNA<213>人類(Homo sapiens)<400>521 cctgtggccg ctcccggctc ggagtgtgat ctaagcaggt tgcgtacctt cctcaggtga61 ctccggccac agcccattgt ccgcggccac cggcggagtt tagccgcaga cctcgaagcg121 ccccggggtc cttcccgaac ggcagcggct gcggcgggtc catggagaag ggccctgtgc181 gggcaccggc ggagaagccg cggggcgcca ggtgcagcaa tgggttcccc gagcgggatc241 cgccgcggcc cgggcccagc aggccggcgg agaagccccc gcggcccgag gccaagagcg301 cgcagcccgc ggacggctgg aagggcgagc ggccccgcag cgaggaggat aacgagctga361 acctccctaa cctggcagcc gcctactcgt ccatcctgag ctcgctgggc gagaaccccc421 agcggcaagg gctgctcaag acgccctgga gggcggcctc ggccatgcag ttcttcacca481 agggctacca ggagactatc tcagatgtcc taaacgatgc tatatttgat gaagatcatg541 atgagatggt gattgtgaag gacatagaca tgttttccat gtgtgagcat cacttggttc601 catttgttgg aaaggtccat attggttatc ttcctaacaa gcaagtcctt ggcctcagca661 aacttgcgag gattgtagaa atctatagta gaagactaca agttcaggag cgccttacaa721 aacaaattgc tgtagcaatc acggaagcct tgcggcctgc tggagtcggg gtagtggttg781 aagcaacaca catgtgtatg gtaatgcgag gtgtacagaa aatgaacagc aaaactgtga841 ccagcacaat gttgggtgtg ttccgggagg atccaaagac tcgggaagag ttcctgactc901 tcattaggag ctgagcttca ttcagtgtgt gtgcgttggt tgccgatcgt actgccagta961 gcattgtctg tctgtccggt cttgtttgta cattccattt tcaattgtta cagatgtgaa1021 ctttattcct tgtcactaat tatatttaaa attatttcta ggaagtcaaa taaatataat1081 aaagggttga gccctctact ttcttcttgc cacctttttg tggcaatatt aaagtgaact1141 gctaatagtg taagtacgtg cacaaaacca ctgccagata accagagggg cctgggaagg1201 gagaagaatt agtgtatttt tttcaaatag tacagtaatt tgcctcataa gcataggagc1261 attgggaatg agagggaact gtgcccagta tactgttttt tttcttcctc caataaaagt1321 ggtgtagtgc cgaaagtgct aaaatattta gtgcggtatt gctctgtgaa ttcaagttca1381 acagacttca ctttggtcat gtttattaaa ccaccagtga catttaaaaa tatattttta1441 gcagtcgtaa tgttagtcac caagggaagg tggtggaatg tctatgtttt tgattttact1501 gtgagttaaa aaggcacatt tctaccttct attgttttta aattcaagaa tagggaatta1561 gttcctggtg ttgtttacga gtgtattctc gtgtcaacat acagggattt agacatttaa1621 ctctctgtgc cttgataaga atatcattta gagtgtagat acttttgcct ttttaaaaaa1681 gccattattt tatgagactt agtactcaca ctgcaaataa ctagtcagct cagttttaac1741 tttataggtt tattgagttt cctttgtgtg atccatgtag atgcctcaaa atgtttcttc1801 ttcttctttt ttttaatctt ataagatatt tttctaagta tttccagaaa catttgagag1861 tgcccatcat tttcaggtct gcagaaccat agcttccacg cacctgaacg agcacagaat1921 gaactgacgg tggaagacat tatgagctgt gtccaacgtt ttaaccaaag cgtatcgtac1981 caacgatctg tgaaaatgca ctggaagctt ctggtcccgg tttcctttgt ggtctatgtg2041 ggtcttgtcc tcattgtaac tccgtataga tggtataggt attttaatcc tggaagctgt2101 tgccttatta atgattatct taaaatttcc tccattgggg cagcgtgggc caaattaaaa2161 caaacaaaac cgcaactcct ccacagaaac acaaacacag ttattccatg aagtttagta2221 tttggttgac atagtgctct tcaaattcat cccattaccc taaaagtaat aactttgatg2281 cttgctttaa ctttagtccc atctctgcca ctttgatgct atttgggtta tgatggggca2341 agatggcaga ggtattgggt ttttttgttt ttttccattc ctctctactt ctgtttccta2401 gctttttctt tctggagttt aagtacagtg atggttggct tgagtacctt tttaaatcta2461 gcccagtata aacattagcc tgcttaatat ttagacattt ataggtagaa ttctgagcac2521 tcaactcatg tttggcattt taaagtaaaa acaagtgtga cttcgaggac caaagaaatt2581 gtcagctata catttatctt tatgaactca tttatattcc tttttaatga ctcgttgttc
2641 taacatttcc tagaagtgtt cttataaagg tctaatgtat ccacaggctg ttgtcttatt2701 agtaaatgca aagtaatgac tttgtctgtt ttactctagt ctttagtact tcaaaattac2761 cttttcatat ccatgatctt gagtccattt gggggatttt taagaatttg atgtatttca2821 atacactgtt caaaattaaa ttgtttaatt ttatgtatga gtatgtatgt tcctgaagtt2881 ggtcctattt aaattattaa actattgtaa ctttgttctt gtgaaaaaaa aaaaaaaaaa2941 a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>53<211>2427<212>DNA<213>人類(Homo sapiens)<400>531 gagagaagga cggagtcgag tggcacccta gaagacgctc tgtgccttcg gaggtctttc61 tgcctgcctg tcctcatgcc tctcctcctc ttgctgctcc tgctgccaag ccccttacac121 ccccacccca tctgtgaggt ctccaaagtg gccagccacc tagaagtgaa ctgtgacaag181 aggaatctga cagcgctgcc tccagacctg ccgaaagaca caaccatcct ccacctgagt241 gagaacctcc tgtacacctt ctccctggca accctgatgc cttacactcg cctcactcag301 ctgaacctag ataggtgcga gctcaccaag ctccaggtcg atgggacgct gccagtgctg361 gggaccctgg atctatccca caatcagctg caaagcctgc ccttgctagg gcagacactg421 cctgctctca ccgtcctgga cgtctccttc aaccggctga cctcgctgcc tcttggtgcc481 ctgcgtggtc ttggcgaact ccaagagctc tacctgaaag gcaatgagct gaagaccctg541 cccccagggc tcctgacgcc cacacccaag ctggagaagc tcagtctggc taacaacaac601 ttgactgagc tccccgctgg gctcctgaat gggctggaga atctcgacac ccttctcctc661 caagagaact cgctgtatac aataccaaag ggcttttttg ggtcccacct cctgcctttt721 gcttttctcc acgggaaccc ctggttatgc aactgtgaga tcctctattt tcgtcgctgg781 ctgcaggaca atgctgaaaa tgtctacgta tggaagcaag gtgtggacgt caaggccatg841 acctctaacg tggccagtgt gcagtgtgac aattcagaca agtttcccgt ctacaaatac901 ccaggaaagg ggtgccccac ccttggtgat gaaggtgaca cagacctata tgattactac961 ccagaagagg acactgaggg cgataaggtg cgtgccacaa ggactgtggt caagttcccc1021 accaaagccc atacaacccc ctggggtcta ttctactcat ggtccactgc ttctctagac1081 agccaaatgc cctcctcctt gcatccaaca caagaatcca ctaaggagca gaccacattc1141 ccacctagat ggaccccaaa tttcacactt cacatggaat ccatcacatt ctccaaaact1201 ccaaaatcca ctactgaacc aaccccaagc ccgaccacct cagagcccgt cccggagccc1261 gccccaaaca tgaccaccct ggagcccact ccaagcccga ccaccccaga gcccacctca1321 gagcccgccc ccagcccgac caccccggag cccaccccaa tcccgaccat cgccacaagc1381 ccgaccatcc tggtgtctgc cacaagcctg atcactccaa aaagcacatt tttaactacc1441 acaaaacccg tatcactctt agaatccacc aaaaaaacca tccctgaact tgatcagcca1501 ccaaagctcc gtggggtgct ccaagggcat ttggagagct ccagaaatga cccttttctc1561 caccccgact tttgctgcct cctccccctg ggcttctatg tcttgggtct cttctggctg1621 ctctttgcct ctgtggtcct catcctgctg ctgagctggg ttgggcatgt gaaaccacag1681 gccctggact ctggccaagg tgctgctctg accacagcca cacaaaccac acacctggag1741 ctgcagaggg gacggcaagt gacagtgccc cgggcctggc tgctcttcct tcgaggttcg1801 cttcccactt tccgctccag cctcttcctg tgggtacggc ctaatggccg tgtggggcct1861 ctagtggcag gaaggaggcc ctcagctctg agtcagggtc gtggtcagga cctgctgagc1921 acagtgagca ttaggtactc tggccacagc ctctgagggt gggaggtttg gggaccttga
1981 gagaagagcc tgtgggctct cctattggaa tctagttggg ggttggaggg gtaaggaaca2041 cagggtgata ggggaggggt cttagttcct ttttctgtat cagaagccct gtcttcacaa2101 cacaggcaca caatttcagt cccagccaaa gcagaagggg taatgacatg gacttggcgg2161 ggggacaaga caaagctccc gatgctgcat ggggcgctgc cagatctcac ggtgaaccat2221 tttggcagaa tacagcatgg ttcccacatg catctatgca cagaagaaaa tctggaaagt2281 gatttatcag gatgtgagca ctcgttgtgt ctggatgtta caaatatggg tggttttatt2341 ttctttttcc ctgtttagca ttttctagtt ttccactatt attgtatatt atctgtataa2401 taaaaaataa ttttagggtt gggaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>54<211>2075<212>DNA<213>人類(Homo sapiens)<400>541 gccataaagg ccgccgcgcg cccacgcgcc tcgcttgctg cgcgctgccg gcgctccttc61 ctcctcggct cgcgtctcac tcagtgtacc ttctagtccc gccatggccg ctctcacccg121 ggacccccag ttccagaagc tgcagcaatg gtaccgcgag caccgctccg agctgaacct181 gcgccgcctc ttcgatgcca acaaggaccg cttcaaccac ttcagcttga ccctcaacac241 caaccatggg catatcctgg tggattactc caagaacctg gtgacggagg acgtgatgcg301 gatgctggtg gacttggcca agtccagggg cgtggaggcc gcccgggagc ggatgttcaa361 tggtgagaag atcaactaca ccgagggtcg agccgtgctg cacgtggctc tgcggaaccg421 gtcaaacaca cccatcctgg tagacggcaa ggatgtgatg ccagaggtca acaaggttct481 ggacaagatg aagtctttct gccagcgtgt ccggagcggt gactggaagg ggtacacagg541 caagaccatc acggacgtca tcaacattgg cattggcggc tccgacctgg gacccctcat601 ggtgactgaa gcccttaagc catactcttc aggaggtccc cgcgtctggt atgtctccaa661 cattgatgga actcacattg ccaaaaccct ggcccagctg aaccccgagt cctccctgtt721 catcattgcc tccaagacct ttactaccca ggagaccatc acgaatgcag agacggcgaa781 ggagtggttt ctccaggcgg ccaaggatcc ttctgcagtg gcgaagcact ttgttgccct841 gtctactaac acaaccaaag tgaaggagtt tggaattgac cctcaaaaca tgttcgagtt901 ctgggattgg gtgggaggac gctactcgct gtggtcggcc atcggactct ccattgccct961 gcacgtgggt tttgacaact tcgagcagct gctctcgggg gctcactgga tggaccagca1021 cttccgcacg acgcccctgg agaagaacgc ccccgtcttg ctggccctgc tgggtatctg1081 gtacatcaac tgctttgggt gtgagacaca cgccatgctg ccctatgacc agtacctgca1141 ccgctttgct gcgtacttcc agcagggcga catggagtcc aatgggaaat acatcaccaa1201 atctggaacc cgtgtggacc accagacagg ccccattgtg tggggggagc cagggaccaa1261 tggccagcat gctttttacc agctcatcca ccaaggcacc aagatgatac cctgtgactt1321 cctcatcccg gtccagaccc agcaccccat acggaagggt ctgcatcaca agatcctcct1381 ggccaacttc ttggcccaga cagaggccct gatgagggga aaatcgacgg aggaggcccg1441 aaaggagctc caggctgcgg gcaagagtcc agaggacctt gagaggctgc tgccacataa1501 ggtctttgaa ggaaatcgcc caaccaactc tattgtgttc accaagctca caccattcat1561 gcttggagcc ttggtcgcca tgtatgagca caagatcttc gttcagggca tcatctggga1621 catcaacagc tttgaccagt ggggagtgga gctgggaaag cagctggcta agaaaataga1681 gcctgagctt gatggcagtg ctcaagtgac ctctcacgac gcttctacca atgggctcat1741 caacttcatc aagcagcagc gcgaggccag agtccaataa actcgtgctc atctgcagcc1801 tcctctgtga ctcccctttc tcttctcgtc cctcctcccc ggagccggca ctgcatgttc
1861 ctggacacca cccagagcac cctctggttg tgggcttgga ccacgagccc ttagcaggga1921 aggctggtct cccccagcct aacccccagc ccctccatgt ctatgctccc tctgtgttag1981 aattggctga agtgtttttg tgcagctgac ttttctgacc catgttcacg ttgttcacat2041 cccatgtaga aaaataaaga tgccacggag gaggt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>55<211>2237<212>DNA<213>人類(Homo sapiens)<400>551 atgaccttgg ctgctttcat ctctgaagcg ccacttctca gaaacacaga gctttagctc61 cgccaaaatg aaacactcat taaacgcact tctcattttc ctcatcataa catctgcgtg121 gggtgggagc aaaggcccgc tggatcagct agagaaagga ggggaaactg ctcagtctgc181 agatccccag tgggagcagt taaataacaa aaacctgagc atgcctcttc tccctgccga241 cttccacaag gaaaacaccg tcaccaacga ctggattcca gagggggagg aggacgacga301 ctatctggac ctggagaaga tattcagtga agacgacgac tacatcgaca tcgtcgacag361 tctgtcagtt tccccgacag actctgatgt gagtgctggg aacatcctcc agctttttca421 tggcaagagc cggatccagc gtcttaacat cctcaacgcc aagttcgctt tcaacctcta481 ccgagtgctg aaagaccagg tcaacacttt cgataacatc ttcatagcac ccgttggcat541 ttctactgcg atgggtatga tttccttagg tctgaaggga gagacccatg aacaagtgca601 ctcgattttg cattttaaag actttgttaa tgccagcagc aagtatgaaa tcacgaccat661 tcataatctc ttccgtaagc tgactcatcg cctcttcagg aggaattttg ggtacacact721 gcggtcagtc aatgaccttt atatccagaa gcagtttcca atcctgcttg acttcaaaac781 taaagtaaga gagtattact ttgctgaggc ccagatagct gacttctcag accctgcctt841 catatcaaaa accaacaacc acatcatgaa gctcaccaag ggcctcataa aagatgctct901 ggagaatata gaccctgcta cccagatgat gattctcaac tgcatctact tcaaaggatc961 ctgggtgaat aaattcccag tggaaatgac acacaaccac aacttccggc tgaatgagag1021 agaggtagtt aaggtttcca tgatgcagac caaggggaac ttcctcgcag caaatgacca1081 ggagctggac tgcgacatcc tccagctgga atacgtgggg ggcatcagca tgctaattgt1141 ggtcccacac aagatgtctg ggatgaagac cctcgaagcg caactgacac cccgggtggt1201 ggagagatgg caaaaaagca tgacaaacag aactcgagaa gtgcttctgc cgaaattcaa1261 gctggagaag aactacaatc tagtggagtc cctgaagttg atggggatca ggatgctgtt1321 tgacaaaaat ggcaacatgg caggcatctc agaccaaagg atcgccatcg acctgttcaa1381 gcaccaaggc acgatcacag tgaacgagga aggcacccaa gccaccactg tgaccacggt1441 ggggttcatg ccgctgtcca cccaagtccg cttcactgtc gaccgcccct ttcttttcct1501 catctacgag catcgcacca gctgcctgct cttcatggga agagtggcca accccagcag1561 gtcctagagg tggaggtcta ggtgtctgaa gtgccttggg ggcaccctca ttttgtttcc1621 attccaacaa cgagaacaga gatgttctgg catcatttac gtagtttacg ctaccaatct1681 gaattcgagg cccatatgag aggagcttag aaacgaccaa gaagagaggc ttgttggaat1741 caattctgca caatagccca tgctgtaagc tcatagaagt cactgtaact gtagtgtgtc1801 tgctgttacc tagagggtct cacctcccca ctcttcacag caaacctgag cagcgcgtcc1861 taagcacctc ccgctccggt gaccccatcc ttgcacacct gactctgtca ctcaagcctt1921 tctccaccag gcccctcatc tgaataccaa gcacagaaat gagtggtgtg actaattcct1981 tacctctccc aaggagggta cacaactagc accattcttg atgtccaggg aagaagccac2041 ctcaagacat atgaggggtg ccctgggcta atgttagggc ttaattttct caaagcctga
2101 cctttcaaat ccatgatgaa tgccatcagt ccctcctgct gttgcctccc tgtgacctgg2161 aggacagtgt gtgccatgtc tcccatacta gagataaata aatgtagcca catttactgt2221 gaaaaaaaaa aaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>56<211>4894<212>DNA<213>人類(Homo sapiens)<400>561 cgccgcggga ggcggacgag atgcgagcgc ggccgcggcc ccggccgctc tgggcgactg61 tgctggcgct gggggcgctg gcgggcgttg gcgtaggagg gcccaacatc tgtaccacgc121 gaggtgtgag ctcctgccag cagtgcctgg ctgtgagccc catgtgtgcc tggtgctctg181 atgaggccct gcctctgggc tcacctcgct gtgacctgaa ggagaatctg ctgaaggata241 actgtgcccc agaatccatc gagttcccag tgagtgaggc ccgagtacta gaggacaggc301 ccctcagcga caagggctct ggagacagct cccaggtcac tcaagtcagt ccccagagga361 ttgcactccg gctccggcca gatgattcga agaatttctc catccaagtg cggcaggtgg421 aggattaccc tgtggacatc tactacttga tggacctgtc ttactccatg aaggatgatc481 tgtggagcat ccagaacctg ggtaccaagc tggccaccca gatgcgaaag ctcaccagta541 acctgcggat tggcttcggg gcatttgtgg acaagcctgt gtcaccatac atgtatatct601 ccccaccaga ggccctcgaa aacccctgct atgatatgaa gaccacctgc ttgcccatgt661 ttggctacaa acacgtgctg acgctaactg accaggtgac ccgcttcaat gaggaagtga721 agaagcagag tgtgtcacgg aaccgagatg ccccagaggg tggctttgat gccatcatgc781 aggctacagt ctgtgatgaa aagattggct ggaggaatga tgcatcccac ttgctggtgt841 ttaccactga tgccaagact catatagcat tggacggaag gctggcaggc attgtccagc901 ctaatgacgg gcagtgtcat gttggtagtg acaatcatta ctctgcctcc actaccatgg961 attatccctc tttggggctg atgactgaga agctatccca gaaaaacatc aatttgatct1021 ttgcagtgac tgaaaatgta gtcaatctct atcagaacta tagtgagctc atcccaggga1081 ccacagttgg ggttctgtcc atggattcca gcaatgtcct ccagctcatt gttgatgctt1141 atgggaaaat ccgttctaaa gtagagctgg aagtgcgtga cctccctgaa gagttgtctc1201 tatccttcaa tgccacctgc ctcaacaatg aggtcatccc tggcctcaag tcttgtatgg1261 gactcaagat tggagacacg gtgagcttca gcattgaggc caaggtgcga ggctgtcccc1321 aggagaagga gaagtccttt accataaagc ccgtgggctt caaggacagc ctgatcgtcc1381 aggtcacctt tgattgtgac tgtgcctgcc aggcccaagc tgaacctaat agccatcgct1441 gcaacaatgg caatgggacc tttgagtgtg gggtatgccg ttgtgggcct ggctggctgg1501 gatcccagtg tgagtgctca gaggaggact atcgcccttc ccagcaggac gaatgcagcc1561 cccgggaggg tcagcccgtc tgcagccagc ggggcgagtg cctctgtggt caatgtgtct1621 gccacagcag tgactttggc aagatcacgg gcaagtactg cgagtgtgac gacttctcct1681 gtgtccgcta caagggggag atgtgctcag gccatggcca gtgcagctgt ggggactgcc1741 tgtgtgactc cgactggacc ggctactact gcaactgtac cacgcgtact gacacctgca1801 tgtccagcaa tgggctgctg tgcagcggcc gcggcaagtg tgaatgtggc agctgtgtct1861 gtatccagcc gggctcctat ggggacacct gtgagaagtg ccccacctgc ccagatgcct1921 gcacctttaa gaaagaatgt gtggagtgta agaagtttga ccggggagcc ctacatgacg1981 aaaatacctg caaccgttac tgccgtgacg agattgagtc agtgaaagag cttaaggaca2041 ctggcaagga tgcagtgaat tgtacctata agaatgagga tgactgtgtc gtcagattcc2101 agtactatga agattctagt ggaaagtcca tcctgtatgt ggtagaagag ccagagtgtc
2161 ccaagggccc tgacatcctg gtggtcctgc tctcagtgat gggggccatt ctgctcattg2221 gccttgccgc cctgctcatc tggaaactcc tcatcaccat ccacgaccga aaagaattcg2281 ctaaatttga ggaagaacgc gccagagcaa aatgggacac agccaacaac ccactgtata2341 aagaggccac gtctaccttc accaatatca cgtaccgggg cacttaatga taagcagtca2401 tcctcagatc attatcagcc tgtgccacga ttgcaggagt ccctgccatc atgtttacag2461 aggacagtat ttgtggggag ggatttgggg ctcagagtgg ggtaggttgg gagaatgtca2521 gtatgtggaa gtgtgggtct gtgtgtgtgt atgtgggggt ctgtgtgttt atgtgtgtgt2581 gttgtgtgtg ggagtgtgta atttaaaatt gtgatgtgtc ctgataagct gagctcctta2641 gcctttgtcc cagaatgcct cctgcaggga ttcttcctgc ttagcttgag ggtgactatg2701 gagctgagca ggtgttcttc attacctcag tgagaagcca gctttcctca tcaggccatt2761 gtccctgaag agaagggcag ggctgaggcc tctcattcca gaggaaggga caccaagcct2821 tggctctacc ctgagttcat aaatttatgg ttctcaggcc tgactctcag cagctatggt2881 aggaactgct gggcttggca gcccgggtca tctgtacctc tgcctccttt cccctccctc2941 aggccgaagg aggagtcagg gagagctgaa ctattagagc tgcctgtgcc ttttgccatc3001 ccctcaaccc agctatggtt ctctcgcaag ggaagtcctt gcaagctaat tctttgacct3061 gttgggagtg aggatgtctg ggccactcag gggtcattca tggcctgggg gatgtaccag3121 catctcccag ttcataatca caacccttca gatttgcctt attggcagct ctactctgga3181 ggtttgttta gaagaagtgt gtcaccctta ggccagcacc atctctttac ctcctaattc3241 cacaccctca ctgctgtaga catttgctat gagctgggga tgtctctcat gaccaaatgc3301 ttttcctcaa agggagagag tgctattgta gagccagagg tctggcccta tgcttccggc3361 ctcctgtccc tcatccatag cacctccaca tacctggccc tgtgccttgg tgtgctgtat3421 ccatccatgg ggctgattgt atttaccttc tacctcttgg ctgccttgtg aaggaattat3481 tcccatgagt tggctgggaa taagtgccag gatggaatga tgggtcagtt gtatcagcac3541 gtgtggcctg ttcttctatg ggttggacaa cctcatttta actcagtctt taatctgaga3601 ggccacagtg caattttatt ttatttttct catgatgagg ttttcttaac ttaaaagaac3661 atgtatataa acatgcttgc attatatttg taaatttatg tgatggcaaa gaaggagagc3721 ataggaaacc acacagactt gggcagggta cagacactcc cacttggcat cattcacagc3781 aagtcactgg ccagtggctg gatctgtgag gggctctctc atgatagaag gctatgggga3841 tagatgtgtg gacacattgg acctttcctg aggaagaggg actgttcttt tgtcccagaa3901 aagcagtggc tccattggtg ttgacataca tccaacatta aaagccaccc ccaaatgccc3961 aagaaaaaaa gaaagactta tcaacatttg ttccatgagc agaaaactgg agctctggcc4021 tcagtgttac agctaaataa tctttaatta aggcaagtca ctttcttctt cttaaagctg4081 ttttctagtt tgagaaatga tgggatttta gcagccagtc ttgaaggtct ctttcagtat4141 caacattcta agatgctggg acttactgtg tcatcaaatg tgcggttaag attctctggg4201 atattgatac tgtttgtgtt tttagttggg agatctgaga gacctggctt tggcaagagc4261 agatgtcatt ccatatcacc tttctcaatg aaagtctcat tctatcctct ctccaaaccc4321 gttttccaac atttgttaat agttacgtct ctcctgatgt agcacttaag cttcatttag4381 ttattatttc tttcttcact ttgcacacat ttgcatccac atattaggga agaggaatcc4441 ataagtagct gaaatatcta ttctgtatta ttgtgttaac attgagaata agccttggaa4501 ttagatatgg ggcaatgact gagccctgtc tcacccatgg attactcctt actgtaggga4561 atggcagtat ggtagaggga taaatagggg gcggggaggg atagtcatgg atccaagaag4621 tccttagaaa tagtggcagg gaacaggtgt ggaagctcat gcctgtaatt ataaccttca4681 gctactaaga caggtgtggt ggctcacgcc tgtgattata atcttcagtt actaagacag4741 agtccatgag agtgttaatg ggacattttc tttagataag atgttttata tgaagaaact4801 gtatcaaagg gggaagaaaa tgtatttaac aggtgaatca aatcaggaat cttgtctgag4861 ctactggaat gaagttcaca ggtcttgaag acca<110>同濟大學附屬同濟醫(yī)院
<120>肺血栓栓塞癥相關基因及其應用<160>142<210>57<211>5896<212>DNA<213>人類(Homo sapiens)<400>571 ctgcggccgg cccgcgagct aggctgggtt tttttttttc tcccctccct cccccctttt61 tccatgcagc tgatctaaaa gggaataaaa ggctgcgcat aatcataata ataaaagaag121 gggagcgcga gagaaggaaa gaaagccggg aggtggaaga ggagggggag cgtctcaaag181 aagcgatcag aataataaaa ggaggccggg ctctttgcct tctggaacgg gccgctcttg241 aaagggcttt tgaaaagtgg tgttgttttc cagtcgtgca tgctccaatc ggcggagtat301 attagagccg ggacgcggcg gccgcagggg cagcggcgac ggcagcaccg gcggcagcac361 cagcgcgaac agcagcggcg gcgtcccgag tgcccgcggc gcgcggcgca gcgatgcgtt421 ccccacggac gcgcggccgg tccgggcgcc ccctaagcct cctgctcgcc ctgctctgtg481 ccctgcgagc caaggtgtgt ggggcctcgg gtcagttcga gttggagatc ctgtccatgc541 agaacgtgaa cggggagctg cagaacggga actgctgcgg cggcgcccgg aacccgggag601 accgcaagtg cacccgcgac gagtgtgaca catacttcaa agtgtgcctc aaggagtatc661 agtcccgcgt cacggccggg gggccctgca gcttcggctc agggtccacg cctgtcatcg721 ggggcaacac cttcaacctc aaggccagcc gcggcaacga ccgcaaccgc atcgtgctgc781 ctttcagttt cgcctggccg aggtcctata cgttgcttgt ggaggcgtgg gattccagta841 atgacaccgt tcaacctgac agtattattg aaaaggcttc tcactcgggc atgatcaacc901 ccagccggca gtggcagacg ctgaagcaga acacgggcgt tgcccacttt gagtatcaga961 tccgcgtgac ctgtgatgac tactactatg gctttggctg caataagttc tgccgcccca1021 gagatgactt ctttggacac tatgcctgtg accagaatgg caacaaaact tgcatggaag1081 gctggatggg ccccgaatgt aacagagcta tttgccgaca aggctgcagt cctaagcatg1141 ggtcttgcaa actcccaggt gactgcaggt gccagtatgg ctggcaaggc ctgtactgtg1201 ataagtgcat cccacacccg ggatgcgtcc acggcatctg taatgagccc tggcagtgcc1261 tctgtgagac caactggggc ggccagctct gtgacaaaga tctcaattac tgtgggactc1321 atcagccgtg tctcaacggg ggaacttgta gcaacacagg ccctgacaaa tatcagtgtt1381 cctgccctga ggggtattca ggacccaact gtgaaattgc tgagcacgcc tgcctctctg1441 atccctgtca caacagaggc agctgtaagg agacctccct gggctttgag tgtgagtgtt1501 ccccaggctg gaccggcccc acatgctcta caaacattga tgactgttct cctaataact1561 gttcccacgg gggcacctgc caggacctgg ttaacggatt taagtgtgtg tgccccccac1621 agtggactgg gaaaacgtgc cagttagatg caaatgaatg tgaggccaaa ccttgtgtaa1681 acgccaaatc ctgtaagaat ctcattgcca gctactactg cgactgtctt cccggctgga1741 tgggtcagaa ttgtgacata aatattaatg actgccttgg ccagtgtcag aatgacgcct1801 cctgtcggga tttggttaat ggttatcgct gtatctgtcc acctggctat gcaggcgatc1861 actgtgagag agacatcgat gaatgtgcca gcaacccctg tttgaatggg ggtcactgtc1921 agaatgaaat caacagattc cagtgtctgt gtcccactgg tttctctgga aacctctgtc1981 agctggacat cgattattgt gagcctaatc cctgccagaa cggtgcccag tgctacaacc2041 gtgccagtga ctatttctgc aagtgccccg aggactatga gggcaagaac tgctcacacc2101 tgaaagacca ctgccgcacg accccctgtg aagtgattga cagctgcaca gtggccatgg2161 cttccaacga cacacctgaa ggggtgcggt atatttcctc caacgtctgt ggtcctcacg2221 ggaagtgcaa gagtcagtcg ggaggcaaat tcacctgtga ctgtaacaaa ggcttcacgg2281 gaacatactg ccatgaaaat attaatgact gtgagagcaa cccttgtaga aacggtggca2341 cttgcatcga tggtgtcaac tcctacaagt gcatctgtag tgacggctgg gagggggcct2401 actgtgaaac caatattaat gactgcagcc agaacccctg ccacaatggg ggcacgtgtc
2461 gcgacctggt caatgacttc tactgtgact gtaaaaatgg gtggaaagga aagacctgcc2521 actcacgtga cagtcagtgt gatgaggcca cgtgcaacaa cggtggcacc tgctatgatg2581 agggggatgc ttttaagtgc atgtgtcctg gcggctggga aggaacaacc tgtaacatag2641 cccgaaacag tagctgcctg cccaacccct gccataatgg gggcacatgt gtggtcaacg2701 gcgagtcctt tacgtgcgtc tgcaaggaag gctgggaggg gcccatctgt gctcagaata2761 ccaatgactg cagccctcat ccctgttaca acagcggcac ctgtgtggat ggagacaact2821 ggtaccggtg cgaatgtgcc ccgggttttg ctgggcccga ctgcagaata aacatcaatg2881 aatgccagtc ttcaccttgt gcctttggag cgacctgtgt ggatgagatc aatggctacc2941 ggtgtgtctg ccctccaggg cacagtggtg ccaagtgcca ggaagtttca gggagacctt3001 gcatcaccat ggggagtgtg ataccagatg gggccaaatg ggatgatgac tgtaatacct3061 gccagtgcct gaatggacgg atcgcctgct caaaggtctg gtgtggccct cgaccttgcc3121 tgctccacaa agggcacagc gagtgcccca gcgggcagag ctgcatcccc atcctggacg3181 accagtgctt cgtccacccc tgcactggtg tgggcgagtg tcggtcttcc agtctccagc3241 cggtgaagac aaagtgcacc tctgactcct attaccagga taactgtgcg aacatcacat3301 ttacctttaa caaggagatg atgtcaccag gtcttactac ggagcacatt tgcagtgaat3361 tgaggaattt gaatattttg aagaatgttt ccgctgaata ttcaatctac atcgcttgcg3421 agccttcccc ttcagcgaac aatgaaatac atgtggccat ttctgctgaa gatatacggg3481 atgatgggaa cccgatcaag gaaatcactg acaaaataat cgatcttgtt agtaaacgtg3541 atggaaacag ctcgctgatt gctgccgttg cagaagtaag agttcagagg cggcctctga3601 agaacagaac agatttcctt gttcccttgc tgagctctgt cttaactgtg gcttggatct3661 gttgcttggt gacggccttc tactggtgcc tgcggaagcg gcggaagccg ggcagccaca3721 cacactcagc ctctgaggac aacaccacca acaacgtgcg ggagcagctg aaccagatca3781 aaaaccccat tgagaaacat ggggccaaca cggtccccat caaggattac gagaacaaga3841 actccaaaat gtctaaaata aggacacaca attctgaagt agaagaggac gacatggaca3901 aacaccagca gaaagcccgg tttgccaagc agccggcgta tacgctggta gacagagaag3961 agaagccccc caacggcacg ccgacaaaac acccaaactg gacaaacaaa caggacaaca4021 gagacttgga aagtgcccag agcttaaacc gaatggagta catcgtatag cagaccgcgg4081 gcactgccgc cgctaggtag agtctgaggg cttgtagttc tttaaactgt cgtgtcatac4141 tcgagtctga ggccgttgct gacttagaat ccctgtgtta atttaagttt tgacaagctg4201 gcttacactg gcaatggtag tttctgtggt tggctgggaa atcgagtgcc gcatctcaca4261 gctatgcaaa aagctagtca acagtaccct ggttgtgtgt ccccttgcag ccgacacggt4321 ctcggatcag gctcccagga gcctgcccag ccccctggtc tttgagctcc cacttctgcc4381 agatgtccta atggtgatgc agtcttagat catagtttta tttatattta ttgactcttg4441 agttgttttt gtatattggt tttatgatga cgtacaagta gttctgtatt tgaaagtgcc4501 tttgcagctc agaaccacag caacgatcac aaatgacttt attatttatt tttttaattg4561 tatttttgtt gttgggggag gggagacttt gatgtcagca gttgctggta aaatgaagaa4621 tttaaagaaa aaaatgtcaa aagtagaact ttgtatagtt atgtaaataa ttctttttta4681 ttaatcactg tgtatatttg atttattaac ttaataatca agagccttaa aacatcattc4741 ctttttattt atatgtatgt gtttagaatt gaaggttttt gatagcattg taagcgtatg4801 gctttatttt tttgaactct tctcattact tgttgcctat aagccaaaat taaggtgttt4861 gaaaatagtt tattttaaaa caataggatg ggcttctgtg cccagaatac tgatggaatt4921 ttttttgtac gacgtcagat gtttaaaaca ccttctatag catcacttaa aacacgtttt4981 aaggactgac tgaggcagtt tgaggattag tttagaacag gtttttttgt ttgtttgttt5041 tttgtttttc tgctttagac ttgaaaagag acaggcaggt gatctgctgc agagcagtaa5101 gggaacaagt tgagctatga cttaacatag ccaaaatgtg agtggttgaa tatgattaaa5161 aatatcaaat taattgtgtg aacttggaag cacaccaatc tgactttgta aattctgatt5221 tcttttcacc attcgtacat aatactgaac cacttgtaga tttgattttt tttttaatct5281 actgcattta gggagtattc taataagcta gttgaatact tgaaccataa aatgtccagt
5341 aagatcactg tttagatttg ccatagagta cactgcctgc cttaagtgag gaaatcaaag5401 tgctattacg aagttcaaga tcaaaaaggc ttataaaaca gagtaatctt gttggttcac5461 cattgagacc gtgaagatac tttgtattgt cctattagtg ttatatgaac atacaaatgc5521 atctttgatg tgttgttctt ggcaataaat tttgaaaagt aatatttatt aaattttttt5581 gtatgaaaac atggaacagt gtggctcttc tgagcttacg tagttctacc ggctttgccg5641 tgtgcttctg ccaccctgct gagtctgttc tggtaatcgg ggtataatag gctctgcctg5701 acagagggat ggaggaagaa ctgaaaggct tttcaaccac aaaactcatc tggagttctc5761 aaagacctgg ggctgctgtg aagctggaac tgcgggagcc ccatctaggg gagccttgat5821 tcccttgtta ttcaacagca agtgtgaata ctgcttgaat aaacaccact ggattaatgg5881 aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>58<211>2732<212>DNA<213>人類(Homo sapiens)<400>581 aacaacatcc tgggattggg acccactttc tgggcactgc tggccagtcc caaaatggaa61 cataaggaag tggttcttct acttctttta tttctgaaat caggtcaagg agagcctctg121 gatgactatg tgaataccca gggggcttca ctgttcagtg tcactaagaa gcagctggga181 gcaggaagta tagaagaatg tgcagcaaaa tgtgaggagg acgaagaatt cacctgcagg241 gcattccaat atcacagtaa agagcaacaa tgtgtgataa tggctgaaaa caggaagtcc301 tccataatca ttaggatgag agatgtagtt ttatttgaaa agaaagtgta tctctcagag361 tgcaagactg ggaatggaaa gaactacaga gggacgatgt ccaaaacaaa aaatggcatc421 acctgtcaaa aatggagttc cacttctccc cacagaccta gattctcacc tgctacacac481 ccctcagagg gactggagga gaactactgc aggaatccag acaacgatcc gcaggggccc541 tggtgctata ctactgatcc agaaaagaga tatgactact gcgacattct tgagtgtgaa601 gaggaatgta tgcattgcag tggagaaaac tatgacggca aaatttccaa gactatgtct661 ggactggaat gccaggcctg ggactctcag agcccacacg ctcatggata cattccttcc721 aaatttccaa acaagaacct gaagaagaat tactgtcgta accccgatag ggagctgcgg781 ccttggtgtt tcaccaccga ccccaacaag cgctgggaac tttgcgacat cccccgctgc841 acaacacctc caccatcttc tggtcccacc taccagtgtc tgaagggaac aggtgaaaac901 tatcgcggga atgtggctgt taccgtttcc gggcacacct gtcagcactg gagtgcacag961 acccctcaca cacataacag gacaccagaa aacttcccct gcaaaaattt ggatgaaaac1021 tactgccgca atcctgacgg aaaaagggcc ccatggtgcc atacaaccaa cagccaagtg1081 cggtgggagt actgtaagat accgtcctgt gactcctccc cagtatccac ggaacaattg1141 gctcccacag caccacctga gctaacccct gtggtccagg actgctacca tggtgatgga1201 cagagctacc gaggcacatc ctccaccacc accacaggaa agaagtgtca gtcttggtca1261 tctatgacac cacaccggca ccagaagacc ccagaaaact acccaaatgc tggcctgaca1321 atgaactact gcaggaatcc agatgccgat aaaggcccct ggtgttttac cacagacccc1381 agcgtcaggt gggagtactg caacctgaaa aaatgctcag gaacagaagc gagtgttgta1441 gcacctccgc ctgttgtcct gcttccagat gtagagactc cttccgaaga agactgtatg1501 tttgggaatg ggaaaggata ccgaggcaag agggcgacca ctgttactgg gacgccatgc1561 caggactggg ctgcccagga gccccataga cacagcattt tcactccaga gacaaatcca1621 cgggcgggtc tggaaaaaaa ttactgccgt aaccctgatg gtgatgtagg tggtccctgg1681 tgctacacga caaatccaag aaaactttac gactactgtg atgtccctca gtgtgcggcc
1741 ccttcatttg attgtgggaa gcctcaagtg gagccgaaga aatgtcctgg aagggttgtg1801 ggggggtgtg tggcccaccc acattcctgg ccctggcaag tcagtcttag aacaaggttt1861 ggaatgcact tctgtggagg caccttgata tccccagagt gggtgttgac tgctgcccac1921 tgcttggaga agtccccaag gccttcatcc tacaaggtca tcctgggtgc acaccaagaa1981 gtgaatctcg aaccgcatgt tcaggaaata gaagtgtcta ggctgttctt ggagcccaca2041 cgaaaagata ttgccttgct aaagctaagc agtcctgccg tcatcactga caaagtaatc2101 ccagcttgtc tgccatcccc aaattatgtg gtcgctgacc ggaccgaatg tttcatcact2161 ggctggggag aaacccaagg tacttttgga gctggccttc tcaaggaagc ccagctccct2221 gtgattgaga ataaagtgtg caatcgctat gagtttctga atggaagagt ccaatccacc2281 gaactctgtg ctgggcattt ggccggaggc actgacagtt gccagggtga cagtggaggt2341 cctctggttt gcttcgagaa ggacaaatac attttacaag gagtcacttc ttggggtctt2401 ggctgtgcac gccccaataa gcctggtgtc tatgttcgtg tttcaaggtt tgttacttgg2461 attgagggag tgatgagaaa taattaattg gacgggagac agagtgacgc actgactcac2521 ctagaggctg ggacgtgggt agggatttag catgctggaa ataactggca gtaatcaaac2581 gaagacactg tccccagcta ccagctacgc caaacctcgg cattttttgt gttattttct2641 gactgctgga ttctgtagta aggtgacata gctatgacat ttgttaaaaa taaactctgt2701 acttaacttt gatttgagta aattttggtt tt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>59<211>1843<212>DNA<213>人類(Homo sapiens)<400>591 ctgcaggggg gggggggggg gggggctgtc atggcggcag gacggcgaac ttgcagtatc61 tccacgaccc gcccctacag gtgccagtgc ctccagaatg tggcagctca caagcctcct121 gctgttcgtg gccacctggg gaatttccgg cacaccagct cctcttgact cagtgttctc181 cagcagcgag cgtgcccacc aggtgctgcg gatccgcaaa cgtgccaact ccttcctgga241 ggagctccgt cacagcagcc tggagcggga gtgcatagag gagatctgtg acttcgagga301 ggccaaggaa attttccaaa atgtggatga cacactggcc ttctggtcca agcacgtcga361 cggtgaccag tgcttggtct tgcccttgga gcacccgtgc gccagcctgt gctgcgggca421 cggcacgtgc atcgacggca tcggcagctt cagctgcgac tgccgcagcg gctgggaggg481 ccgcttctgc cagcgcgagg tgagcttcct caattgctcg ctggacaacg gcggctgcac541 gcattactgc ctagaggagg tgggctggcg gcgctgtagc tgtgcgcctg gctacaagct601 gggggacgac ctcctgcagt gtcaccccgc agtgaagttc ccttgtggga ggccctggaa661 gcggatggag aagaagcgca gtcacctgaa acgagacaca gaagaccaag aagaccaagt721 agatccgcgg ctcattgatg ggaagatgac caggcgggga gacagcccct ggcaggtggt781 cctgctggac tcaaagaaga agctggcctg cggggcagtg ctcatccacc cctcctgggt841 gctgacagcg gcccactgca tggatgagtc caagaagctc cttgtcaggc ttggagagta901 tgacctgcgg cgctgggaga agtgggagct ggacctggac atcaaggagg tcttcgtcca961 ccccaactac agcaagagca ccaccgacaa tgacatcgca ctgctgcacc tggcccagcc1021 cgccaccctc tcgcagacca tagtgcccat ctgcctcccg gacagcggcc ttgcagagcg1081 cgagctcaat caggccggcc aggagaccct cgtgacgggc tggggctacc acagcagccg1141 agagaaggag gccaagagaa accgcacctt cgtcctcaac ttcatcaaga ttcccgtggt1201 cccgcacaat gagtgcagcg aggtcatgag caacatggtg tctgagaaca tgctgtgtgc1261 gggcatcctc ggggaccggc aggatgcctg cgagggcgac agtggggggc ccatggtcgc
1321 ctccttccac ggcacctggt tcctggtggg cctggtgagc tggggtgagg gctgtgggct1381 ccttcacaac tacggcgttt acaccaaagt cagccgctac ctcgactgga tccatgggca1441 catcagagac aaggaagccc cccagaagag ctgggcacct tagcgaccct ccctgcaggg1501 ctgggctttt gcatggcaat ggatgggaca ttaaagggac atgtaacaag cacaccggcc1561 tgctgttctg tccttccatc cctcttttgg gctcttctgg agggaagtaa catttactga1621 gcacctgttg tatgtcacat gccttatgaa tagaatctta actcctagag caactctgtg1681 gggtggggag gagcagatcc aagttttgcg gggtctaaag ctgtgtgtgt tgagggggat1741 actctgttta tgaaaaagaa taaaaaacac aaccacgaaa aaaaaaaaaa aaaaaaaaaa1801 aaaaaaaaaa aaaaaaaccc ccccccgccc cccccccctg cag<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>60<211>3309<212>DNA<213>人類(Homo sapiens)<400>601 ctgcaggggg gggggggggg gggggggggg ggggggggcg cagcacggct cagaccgagg61 cgcacaggct cgcagctccg ggcgcctagc gcccggtccc cgccgcgacg cgccaccgtc121 cctgccggcg cctccgcgcc ttcgaaatga gggtcctggg tgggcgctgc ggggcgccgc181 tggcgtgtct cctcctagtg cttcccgtct cagaggcaaa ccttctgtca aagcaacagg241 cttcacaagt cctggttagg aagcgtcgtg caaattcttt acttgaagaa accaaacagg301 gtaatcttga aagagaatgc atcgaagaac tgtgcaataa agaagaagcc agggaggtct361 ttgaaaatga cccggaaacg gattattttt atccaaaata cttagtttgt cttcgctctt421 ttcaaactgg gttattcact gctgcacgtc agtcaactaa tgcttatcct gacctaagaa481 gctgtgtcaa tgccattcca gaccagtgta gtcctctgcc atgcaatgaa gatggatata541 tgagctgcaa agatggaaaa gcttctttta cttgcacttg taaaccaggt tggcaaggag601 aaaagtgtga atttgacata aatgaatgca aagatccctc aaatataaat ggaggttgca661 gtcaaatttg tgataataca cctggaagtt accactgttc ctgtaaaaat ggttttgtta721 tgctttcaaa taagaaagat tgtaaagatg tggatgaatg ctctttgaag ccaagcattt781 gtggcacagc tgtgtgcaag aacatcccag gagattttga atgtgaatgc cccgaaggct841 acagatataa tctcaaatca aagtcttgtg aagatataga tgaatgctct gagaacatgt901 gtgctcagct ttgtgtcaat taccctggag gttacacttg ctattgtgat gggaagaaag961 gattcaaact tgcccaagat cagaagagtt gtgaggttgt ttcagtgtgc cttcccttga1021 accttgacac aaagtatgaa ttactttact tggcggagca gtttgcaggg gttgttttat1081 atttaaaatt tcgtttgcca gaaatcagca gattttcagc agaatttgat ttccggacat1141 atgattcaga aggcgtgata ctgtacgcag aatctatcga tcactcagcg tggctcctga1201 ttgcacttcg tggtggaaag attgaagttc agcttaagaa tgaacataca tccaaaatca1261 caactggagg tgatgttatt aataatggtc tatggaatat ggtgtctgtg gaagaattag1321 aacatagtat tagcattaaa atagctaaag aagctgtgat ggatataaat aaacctggac1381 ccctttttaa gccggaaaat ggattgctgg aaaccaaagt atactttgca ggattccctc1441 ggaaagtgga aagtgaactc attaaaccga ttaaccctcg tctagatgga tgtatacgaa1501 gctggaattt gatgaagcaa ggagcttctg gaataaagga aattattcaa gaaaaacaaa1561 ataagcattg cctggttact gtggagaagg gctcctacta tcctggttct ggaattgctc1621 aatttcacat agattataat aatgtatcca gtgctgaggg ttggcatgta aatgtgacct1681 tgaatattcg tccatccacg ggcactggtg ttatgcttgc cttggtttct ggtaacaaca1741 cagtgccctt tgctgtgtcc ttggtggact ccacctctga aaaatcacag gatattctgt
1801 tatctgttga aaatactgta atatatcgga tacaggccct aagtctatgt tccgatcaac1861 aatctcatct ggaatttaga gtcaacagaa acaatctgga gttgtcgaca ccacttaaaa1921 tagaaaccat ctcccatgaa gaccttcaaa gacaacttgc cgtcttggac aaagcaatga1981 aagcaaaagt ggccacatac ctgggtggcc ttccagatgt tccattcagt gccacaccag2041 tgaatgcctt ttataatggc tgcatggaag tgaatattaa tggtgtacag ttggatctgg2101 atgaagccat ttctaaacat aatgatatta gagctcactc atgtccatca gtttggaaaa2161 agacaaagaa ttcttaaggc atcttttctc tgcttataat accttttcct tgtgtgtaat2221 tatacttatg tttcaataac agctgaaggg ttttatttac aatgtgcagt ctttgattat2281 tttgtggtcc tttcctggga tttttaaaag gtcctttgtc aaggaaaaaa attctgttgt2341 gatataaatc acagtaaaga aattcttact tctcttgcta tctaagaata gtgaaaaata2401 acaattttaa atttgaattt ttttcctaca aatgacagtt tcaatttttg tttgtaaaac2461 taaattttaa ttttatcatc atgaactagt gtctaaatac ctatgttttt ttcagaaagc2521 aaggaagtaa actcaaacaa aagtgcgtgt aattaaatac tattaatcat aggcagatac2581 tattttgttt atgtttttgt ttttttcctg atgaaggcag aagagatggt ggtctattaa2641 atatgaattg aatggagggt cctaatgcct tatttcaaaa caattcctca gggggaccag2701 ctttggcttc atctttctct tgtgtggctt cacatttaaa ccagtatctt tattgaatta2761 gaaaacaagt gggacatatt ttcctgagag cagcacagga atcttcttct tggcagctgc2821 agtctgtcag gatgagatat cagattaggt tggataggtg gggaaatctg aagtgggtac2881 attttttaaa ttttgctgtg tgggtcacac aaggtctaca ttacaaaaga cagaattcag2941 ggatggaaag gagaatgaac aaatgtggga gttcatagtt ttccttgaat ccaactttta3001 attaccagag taagttgcca aaatgtgatt gttgaagtac aaaaggaact atgaaaacca3061 gaacaaattt taacaaaagg acaaccacag agggatatag tgaatatcgt atcattgtaa3121 tcaaagaagt aaggaggtaa gattgccacg tgcctgctgg tactgtgatg catttcaagt3181 ggcagtttta tcacgtttga atctaccatt catagccaga tgtgtatcag atgtttcact3241 gacagttttt aacaataaat tcttttcact gtattttata tcacttataa taaatcggtg3301 tataatttt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>61<211>4048<212>DNA<213>人類(Homo sapiens)<400>611 ggctgcctcg caggggctgc gcgcagcggc aagaagtgtc tgggctggga cggacaggag61 aggctgtcgc catcggcgtc ctgtgcccct ctgctccggc acggccctgt cgcagtgccc121 gcgctttccc cggcgcctgc acgcggcgcg cctgggtaac atgcttgggg tcctggtcct181 tggcgcgctg gccctggccg gcctggggtt ccccgcaccc gcagagccgc agccgggtgg241 cagccagtgc gtcgagcacg actgcttcgc gctctacccg ggccccgcga ccttcctcaa301 tgccagtcag atctgcgacg gactgcgggg ccacctaatg acagtgcgct cctcggtggc361 tgccgatgtc atttccttgc tactgaacgg cgacggcggc gttggccgcc ggcgcctctg421 gatcggcctg cagctgccac ccggctgcgg cgaccccaag cgcctcgggc ccctgcgcgg481 cttccagtgg gttacgggag acaacaacac cagctatagc aggtgggcac ggctcgacct541 caatggggct cccctctgcg gcccgttgtg cgtcgctgtc tccgctgctg aggccactgt601 gcccagcgag ccgatctggg aggagcagca gtgcgaagtg aaggccgatg gcttcctctg661 cgagttccac ttcccagcca cctgcaggcc actggctgtg gagcccggcg ccgcggctgc721 cgccgtctcg atcacctacg gcaccccgtt cgcggcccgc ggagcggact tccaggcgct
781 gccggtgggc agctccgccg cggtggctcc cctcggctta cagctaatgt gcaccgcgcc841 gcccggagcg gtccaggggc actgggccag ggaggcgccg ggcgcttggg actgcagcgt901 ggagaacggc ggctgcgagc acgcgtgcaa tgcgatccct ggggctcccc gctgccagtg961 cccagccggc gccgccctgc aggcagacgg gcgctcctgc accgcatccg cgacgcagtc1021 ctgcaacgac ctctgcgagc acttctgcgt tcccaacccc gaccagccgg gctcctactc1081 gtgcatgtgc gagaccggct accggctggc ggccgaccaa caccggtgcg aggacgtgga1141 tgactgcata ctggagccca gtccgtgtcc gcagcgctgt gtcaacacac agggtggctt1201 cgagtgccac tgctacccta actacgacct ggtggacggc gagtgtgtgg agcccgtgga1261 cccgtgcttc agagccaact gcgagtacca gtgccagccc ctgaaccaaa ctagctacct1321 ctgcgtctgc gccgagggct tcgcgcccat tccccacgag ccgcacaggt gccagatgtt1381 ttgcaaccag actgcctgtc cagccgactg cgaccccaac acccaggcta gctgtgagtg1441 ccctgaaggc tacatcctgg acgacggttt catctgcacg gacatcgacg agtgcgaaaa1501 cggcggcttc tgctccgggg tgtgccacaa cctccccggt accttcgagt gcatctgcgg1561 gcccgactcg gcccttgccc gccacattgg caccgactgt gactccggca aggtggacgg1621 tggcgacagc ggctctggcg agcccccgcc cagcccgacg cccggctcca ccttgactcc1681 tccggccgtg gggctcgtgc attcgggctt gctcataggc atctccatcg cgagcctgtg1741 cctggtggtg gcgcttttgg cgctcctctg ccacctgcgc aagaagcagg gcgccgccag1801 ggccaagatg gagtacaagt gcgcggcccc ttccaaggag gtagtgctgc agcacgtgcg1861 gaccgagcgg acgccgcaga gactctgagc ggcctccgtc caggagcctg gctccgtcca1921 ggagcctgtg cctcctcacc cccagctttg ctaccaaagc accttagctg gcattacagc1981 tggagaagac cctccccgca ccccccaagc tgttttcttc tattccatgg ctaactggcg2041 agggggtgat tagagggagg agaatgagcc tcggcctctt ccgtgacgtc actggaccac2101 tgggcaatga tggcaatttt gtaacgaaga cacagactgc gatttgtccc aggtcctcac2161 taccgggcgc aggagggtga gcgttattgg tcggcagcct tctgggcaga ccttgacctc2221 gtgggctagg gatgactaaa atatttattt tttttaagta tttaggtttt tgtttgtttc2281 ctttgttctt acctgtatgt ctccagtatc cactttgcac agctctccgg tctctctctc2341 tctacaaact cccacttgtc atgtgacagg taaactatct tggtgaattt ttttttccta2401 gccctctcac atttatgaag caagccccac ttattcccca ttcttcctag ttttctcctc2461 ccaggaactg ggccaactca cctgagtcac cctacctgtg cctgacccta cttcttttgc2521 tcttagctgt ctgctcagac agaaccccta catgaaacag aaacaaaaac actaaaaata2581 aaaatggcca tttgcttttt caccagattt gctaatttat cctgaaattt cagattccca2641 gagcaaaata attttaaaca aaggttgaga tgtaaaaggt attaaattga tgttgctgga2701 ctgtcataga aattacaccc aaagaggtat ttatctttac ttttaaacag tgagcctgaa2761 ttttgttgct gttttgattt gtactgaaaa atggtaattg ttgctaatct tcttatgcaa2821 tttccttttt tgttattatt acttattttt gacagtgttg aaaatgttca gaaggttgct2881 ctagattgag agaagagaca aacacctccc aggagacagt tcaagaaagc ttcaaactgc2941 atgattcatg ccaattagca attgactgtc actgttcctt gtcactggta gaccaaaata3001 aaaccagctc tactggtctt gtggaattgg gagcttggga atggatcctg gaggatgccc3061 aattagggcc tagccttaat caggtcctca gagaatttct accatttcag agaggccttt3121 tggaatgtgg cccctgaaca agaattggaa gctgccctgc ccatgggagc tggttagaaa3181 tgcagaatcc taggctccac cccatccagt tcatgagaat ctatatttaa caagatctgc3241 agggggtgtg tctgctcagt aatttgagga caaccattcc agactgcttc caattttctg3301 gaatacatga aatatagatc agttataagt agcaggccaa gtcaggccct tattttcaag3361 aaactgagga attttctttg tgtagctttg ctctttggta gaaaaggcta ggtacacagc3421 tctagacact gccacacagg gtctgcaagg tctttggttc agctaagcta ggaatgaaat3481 cctgcttcag tgtatggaaa taaatgtatc atagaaatgt aacttttgta agacaaaggt3541 tttcctcttc tattttgtaa actcaaaata tttgtacata gttatttatt tattggagat3601 aatctagaac acaggcaaaa tccttgctta tgacatcact tgtacaaaat aaacaaataa
3661 caatgtgctc tcgggttgtg tgtctgttca cttttcctcc ctcagtgccc tcattttatg3721 tcattaaatg gggctcacaa accatgcaaa tgctatgaga tgcatggagg gctgccctgt3781 accccagcac ttgtgttgtc tggtggtggc accatctctg attttcaaag ctttttccag3841 aggctattat tttcactgta gaatgatttc atgctatctc tgtgtgcaca aatatttatt3901 ttctttctgt aaccataaca acttcatata tgaggacttg tgtctctgtg cttttaaatg3961 cataaatgca ttataggatc atttgttgga atgaattaaa taaacccttc ctggggcatc4021 tggcgaatcc caaaaaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>62<211>1806<212>DNA<213>人類(Homo sapiens)<400>621 agcctcgcca gagaagacaa gggcagaaag caccatgagt gggggcccaa tgggaggaag61 gcccgggggc cgaggagcac cagcggttca gcagaacata ccctccaccc tcctccagga121 ccacgagaac cagcgactct ttgagatgct tggacgaaaa tgcttgacgc tggccactgc181 agttgttcag ctgtacctgg cgctgccccc tggagctgag cactggacca aggagcattg241 tggggctgtg tgcttcgtga aggataaccc ccagaagtcc tacttcatcc gcctttacgg301 ccttcaggct ggtcggctgc tctgggaaca ggagctgtac tcacagcttg tctactccac361 ccccaccccc ttcttccaca ccttcgctgg agatgactgc caagcggggc tgaactttgc421 agacgaggac gaggcccagg ccttccgggc cctcgtgcag gagaagatac aaaaaaggaa481 tcagaggcaa agtggagaca gacgccagct acccccacca ccaacaccag ccaatgaaga541 gagaagagga gggctcccac ccctgcccct gcatccaggt ggagaccaag gaggccctcc601 agtgggtccg ctctccctgg ggctggcgac agtggacatc cagaaccctg acatcacgag661 ttcacgatac cgtgggctcc cagcacctgg acctagccca gctgataaga aacgctcagg721 gaagaagaag atcagcaaag ctgatattgg tgcacccagt ggattcaagc atgtcagcca781 cgtggggtgg gacccccaga atggatttga cgtgaacaac ctcgacccag atctgcggag841 tctgttctcc agggcaggaa tcagcgaggc ccagctcacc gacgccgaga cctctaaact901 tatctacgac ttcattgagg accagggtgg gctggaggct gtgcggcagg agatgaggcg961 ccaggagcca cttccgccgc ccccaccgcc atctcgagga gggaaccagc tcccccggcc1021 ccctattgtg gggggtaaca agggtcgttc tggtccactg ccccctgtac ctttggggat1081 tgccccaccc ccaccaacac cccggggacc cccaccccca ggccgagggg gccctccacc1141 accaccccct ccagctactg gacgttctgg accactgccc cctccacccc ctggagctgg1201 tgggccaccc atgccaccac caccgccacc accgccaccg ccgcccagct ccgggaatgg1261 accagcccct cccccactcc ctcctgctct ggtgcctgcc gggggcctgg cccctggtgg1321 gggtcgggga gcgcttttgg atcaaatccg gcagggaatt cagctgaaca agacccctgg1381 ggccccagag agctcagcgc tgcagccacc acctcagagc tcagagggac tggtgggggc1441 cctgatgcac gtgatgcaga agagaagcag agccatccac tcctccgacg aaggggagga1501 ccaggctggc gatgaagatg aagatgatga atgggatgac tgagtggctg agttacttgc1561 tgccctgtgc tcctccccgc aggacatggc tccccctcca cctgctctgt gcccaccctc1621 cactctcctc ttccagggcc cccaaccccc catttcttcc ccaccaaccc ctccaatgct1681 gttatccctg cctggtcctc acactcaccc aacaatccca aggccctttt tatacaaaaa1741 ttctcagttc tcttcactca aggattttta aagaaaaata aaagaattgt ctttctgtct1801 ctctat
<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>63<211>1978<212>DNA<213>人類(Homo sapiens)<400>631 ctgctccgga gtgacgcggg cccgggcgcg acggtctcgg cggcggcggc ggcggcgaca61 gagcgagcgc ggcgcggggc caccatgggg gcccagctca gcacgttggg ccatatggtg121 ctcttcccag tctggttcct gtacagtctg ctcatgaagc tgttccagcg ctccacgcca181 gccatcaccc tcgagagccc ggacatcaag tacccgctgc ggctcatcga ccgggagatc241 atcagccatg acacccggcg cttccgcttt gccctgccgt caccccagca catcctgggc301 ctccctgtcg gccagcacat ctacctctcg gctcgaattg atggaaacct ggtcgtccgg361 ccctatacac ccatctccag cgatgatgac aagggcttcg tggacctggt catcaaggtt421 tacttcaagg acacccatcc caagtttccc gctggaggga agatgtctca gtacctggag481 agcatgcaga ttggagacac cattgagttc cggggcccca gtgggctgct ggtctaccag541 ggcaaaggga agttcgccat ccgacctgac aaaaagtcca accctatcat caggacagtg601 aagtctgtgg gcatgatcgc gggagggaca ggcatcaccc cgatgctgca ggtgatccgc661 gccatcatga aggaccctga tgaccacact gtgtgccacc tgctctttgc caaccagacc721 gagaaggaca tcctgctgcg acctgagctg gaggaactca ggaacaaaca ttctgcacgc781 ttcaagctct ggtacacgct ggacagagcc cctgaagcct gggactacgg ccagggcttc841 gtgaatgagg agatgatccg ggaccacctt ccacccccag aggaggagcc gctggtgctg901 atgtgtggcc ccccacccat gatccagtac gcctgccttc ccaacctgga ccacgtgggc961 caccccacgg agcgctgctt cgtcttctga gggccgggca cggtcacacg gccacccgcc1021 ccgcgcaccc cacgccctgt tcacgctcac ccagtcacct ccccacatcg cacactgggg1081 ccccgggttc agcctggcct gcccgtgccc tggtgaatca cctggctgag cagttcccct1141 ggagcccctt cgggagcagg gctgtgtccc agatgggcca cggctgagcc ttcagagtac1201 gtcctgcctg gcacttactg gtccttacca gagacgccca gccccatccc tgtcctcatg1261 acccctcgtc caccccccac acacactata aggctgaggg ctgccagcag ccccgtctgc1321 ccaccattcc cggccgtgga ccatagtcgg gatgtcagca gacacacatg ggcagcccaa1381 agctgcaggt gccagggccc accccagcct cgcctgtcac ccccactccc gcctcagggc1441 caggcccagg cctcaccacc tgacgctgca tgagacattg acaccagaaa gccctcttgg1501 gggcactgct ccctacccca gggccctggc cagccgggag cttggctctc ctctggctag1561 agtgggaaga gggggctggc catggggccc tcccagaacc tcagcatttc cttccagccc1621 atccaaacac tgaggcagcc ttggggaacc ccgagctggg gggttggcag cccactgcac1681 cgcctcaggg ttttggggtc ctgggctggg gccaccatcc ctgatggcag aactcccaca1741 accacatgta tttattcctc tgtcctaaac cgtcccctcc ttccctcacc cccagcacag1801 ggggattctg agcagtgcct cttgtctgag ggacatatca gtgacctcga cgttgccttt1861 agactacagt tgtgttagcc tcttgcgtat tggctttttc agagtcattt atgagcagaa1921 aaaaaaaaag taaaactttg ctaatattaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>64<211>6557<212>DNA
<213>人類(Homo sapiens)<400>641 agagggcaag gagagagcag agaacacact ttgccttctc tttggtattg agtaatatca61 accaaattgc agacatctca acactttggc caggcagcct gctgagcaag gtatttcagc121 cagcatggca gcctctttcc cacccacctt gggactcagt tctgccccag atgaaattca181 gcacccacat attaaatttt cagaatggaa atttaagctg ttccgggtga gatcctttga241 aaagacacct gaagaagctc aaaaggaaaa gaaggattcc tttgagggga aaccctctct301 ggagcaatct ccagcagtcc tggacaaggc tgatggtcag aagccagtcc caactcagcc361 attgttaaaa gcccacccta agttttcaaa gaaatttcac gacaacgaga aagcaagagg421 caaagcgatc catcaagcca accttcgaca tctctgccgc atctgtggga attcttttag481 agctgatgag cacaacagga gatatccagt ccatggtcct gtggatggta aaaccctagg541 ccttttacga aagaaggaaa agagagctac ttcctggccg gacctcattg ccaaggtttt601 ccggatcgat gtgaaggcag atgttgactc gatccacccc actgagttct gccataactg661 ctggagcatc atgcacagga agtttagcag tgccccatgt gaggtttact tcccgaggaa721 cgtgaccatg gagtggcacc cccacacacc atcctgtgac atctgcaaca ctgcccgtcg781 gggactcaag aggaagagtc ttcagccaaa cttgcagctc agcaaaaaac tcaaaactgt841 gcttgaccaa gcaagacaag cccgtcagcg caagagaaga gctcaggcaa ggatcagcag901 caaggatgtc atgaagaaga tcgccaactg cagtaagata catcttagta ccaagctcct961 tgcagtggac ttcccagagc actttgtgaa atccatctcc tgccagatct gtgaacacat1021 tctggctgac cctgtggaga ccaactgtaa gcatgtcttt tgccgggtct gcattctcag1081 atgcctcaaa gtcatgggca gctattgtcc ctcttgccga tatccatgct tccctactga1141 cctggagagt ccagtgaagt cctttctgag cgtcttgaat tccctgatgg tgaaatgtcc1201 agcaaaagag tgcaatgagg aggtcagttt ggaaaaatat aatcaccaca tctcaagtca1261 caaggaatca aaagagattt ttgtgcacat taataaaggg ggccggcccc gccaacatct1321 tctgtcgctg actcggagag ctcagaagca ccggctgagg gagctcaagc tgcaagtcaa1381 agcctttgct gacaaagaag aaggtggaga tgtgaagtcc gtgtgcatga ccttgttcct1441 gctggctctg agggcgagga atgagcacag gcaagctgat gagctggagg ccatcatgca1501 gggaaagggc tctggcctgc agccagctgt ttgcttggcc atccgtgtca acaccttcct1561 cagctgcagt cagtaccaca agatgtacag gactgtgaaa gccatcacag ggagacagat1621 ttttcagcct ttgcatgccc ttcggaatgc tgagaaggta cttctgccag gctaccacca1681 ctttgagtgg cagccacctc tgaagaatgt gtcttccagc actgatgttg gcattattga1741 tgggctgtct ggactatcat cctctgtgga tgattaccca gtggacacca ttgcaaagag1801 gttccgctat gattcagctt tggtgtctgc tttgatggac atggaagaag acatcttgga1861 aggcatgaga tcccaagacc ttgatgatta cctgaatggc cccttcactg tggtggtgaa1921 ggagtcttgt gatggaatgg gagacgtgag tgagaagcat gggagtgggc ctgtagttcc1981 agaaaaggca gtccgttttt cattcacaat catgaaaatt actattgccc acagctctca2041 gaatgtgaaa gtatttgaag aagccaaacc taactctgaa ctgtgttgca agccattgtg2101 ccttatgctg gcagatgagt ctgaccacga gacgctgact gccatcctga gtcctctcat2161 tgctgagagg gaggccatga agagcagtga attaatgctt gagctgggag gcattctccg2221 gactttcaag ttcatcttca ggggcaccgg ctatgatgaa aaacttgtgc gggaagtgga2281 aggcctcgag gcttctggct cagtctacat ttgtactctt tgtgatgcca cccgtctgga2341 agcctctcaa aatcttgtct tccactctat aaccagaagc catgctgaga acctggaacg2401 ttatgaggtc tggcgttcca acccttacca tgagtctgtg gaagaactgc gggatcgggt2461 gaaaggggtc tcagctaaac ctttcattga gacagtccct tccatagatg cactccactg2521 tgacattggc aatgcagctg agttctacaa gatcttccag ctagagatag gggaagtgta2581 taagaatccc aatgcttcca aagaggaaag gaaaaggtgg caggccacac tggacaagca2641 tctccggaag aagatgaacc tcaaaccaat catgaggatg aatggcaact ttgccaggaa2701 gctcatgacc aaagagactg tggatgcagt ttgtgagtta attccttccg aggagaggca
2761 cgaggctctg agggagctga tggatcttta cctgaagatg aaaccagtat ggcgatcatc2821 atgccctgct aaagagtgcc cagaatccct ctgccagtac agtttcaatt cacagcgttt2881 tgctgagctc ctttctacga agttcaagta taggtatgag ggaaaaatca ccaattattt2941 tcacaaaacc ctggcccatg ttcctgaaat tattgagagg gatggctcca ttggggcatg3001 ggcaagtgag ggaaatgagt ctggtaacaa actgtttagg cgcttccgga aaatgaatgc3061 caggcagtcc aaatgctatg agatggaaga tgtcctgaaa caccactggt tgtacacctc3121 caaatacctc cagaagttta tgaatgctca taatgcatta aaaacctctg ggtttaccat3181 gaaccctcag gcaagcttag gggacccatt aggcatagag gactctctgg aaagccaaga3241 ttcaatggaa ttttaagtag ggcaaccact tatgagttgg tttttgcaat tgagtttccc3301 tctgggttgc attgagggct tctcctagca ccctttactg ctgtgtatgg ggcttcacca3361 tccaagaggt ggtaggttgg agtaagatgc tacagatgct ctcaagtcag gaatagaaac3421 tgatgagctg attgcttgag gcttttagtg agttccgaaa agcaacagga aaaatcagtt3481 atctgaaagc tcagtaactc agaacaggag taactgcagg ggaccagaga tgagcaaaga3541 tctgtgtgtg ttggggagct gtcatgtaaa tcaaagccaa ggttgtcaaa gaacagccag3601 tgaggccaga aattggtctt gtggttttca tttttttccc ccttgattga ttatattttg3661 tattgagata tgataagtgc cttctatttc atttttgaat aattcttcat ttttataatt3721 ttacatatct tggcttgcta tataagattc aaaagagctt tttaaatttt tctaataata3781 tcttacattt gtacagcatg atgaccttta caaagtgctc tcaatgcatt tacccattcg3841 ttatataaat atgttacatc aggacaactt tgagaaaatc agtccttttt tatgtttaaa3901 ttatgtatct attgtaacct tcagagttta ggaggtcatc tgctgtcatg gatttttcaa3961 taatgaattt agaatacacc tgttagctac agttagttat taaatcttct gataatatat4021 gtttacttag ctatcagaag ccaagtatga ttctttattt ttactttttc atttcaagaa4081 atttagagtt tccaaattta gagcttctgc atacagtctt aaagccacag aggcttgtaa4141 aaatataggt tagcttgatg tctaaaaata tatttcatgt cttactgaaa cattttgcca4201 gactttctcc aaatgaaacc tgaatcaatt tttctaaatc taggtttcat agagtcctct4261 cctctgcaat gtgttattct ttctataatg atcagtttac tttcagtgga ttcagaattg4321 tgtagcagga taaccttgta tttttccatc cgctaagttt agatggagtc caaacgcagt4381 acagcagaag agttaacatt tacacagtgc tttttaccac tgtggaatgt tttcacactc4441 atttttcctt acaacaattc tgaggagtag gtgttgttat tatctccatt tgatgggggt4501 ttaatgattt gctcaaagtc atttaggggt aataaatact tggcttggaa atttaacaca4561 gtccttttgt ctccaaagcc cttcttcttt ccaccacaaa ttaatcacta tgtttataag4621 gtagtatcag aattttttta ggattcacaa ctaatcacta tagcacatga ccttgggatt4681 acatttttat ggggcagggg taagcggctt ttaaatcatt tgtgtgctct ggctcttttg4741 atagaagaaa gcaacacaaa agctccaaag ggccccctaa ccctcttgtg gctccagtta4801 tttggaaact atgatctgca tccttaggaa tctgggattt gccagttgct ggcaatgtag4861 agcaggcatg gaattttata tgctagtgag tcataatgat atgttagtgt taattagttt4921 ttcttccttt gattttattg gccataattg ctactcttca tacacagtat atcaaagagc4981 ttgataattt agttgtcaaa agtgcatcgg cgacattatc tttaattgta tgtatttggt5041 gcttcttcag ggattgaact cagtatcttt cattaaaaaa cacagcagtt ttccttgctt5101 tttatatgca gaatatcaaa gtcatttcta atttagttgt caaaaacata tacatatttt5161 aacattagtt tttttgaaaa ctcttggttt tgtttttttg gaaatgagtg ggccactaag5221 ccacactttc ccttcatcct gcttaatcct tccagcatgt ctctgcacta ataaacagct5281 aaattcacat aatcatccta tttactgaag catggtcatg ctggtttata gattttttac5341 ccatttctac tctttttctc tattggtggc actgtaaata ctttccagta ttaaattatc5401 cttttctaac actgtaggaa ctattttgaa tgcatgtgac taagagcatg atttatagca5461 caacctttcc aataatccct taatcagatc acattttgat aaaccctggg aacatctggc5521 tgcaggaatt tcaatatgta gaaacgctgc ctatggtttt ttgcccttac tgttgagact5581 gcaatatcct agaccctagt tttatactag agttttattt ttagcaatgc ctattgcaag
5641 tgcaattata tactccaggg aaattcacca cactgaatcg agcatttgtg tgtgtatgtg5701 tgaagtatat ctgggacttc agaagtgcaa tgtatttttc tcctgtgaaa cctgaatcta5761 caagttttct gccaagccac tcaggtgcat tgcagggacc agtgataatg gctgatgaaa5821 attgatgatt ggtcagtgag gtcaaaagga gccttgggat taataaacat gcactgagaa5881 gcaagaggag gagaaaaaga tgtctttttc ttccaggtga actggaattt agttttgcct5941 cagatttttt tcccacaaga tacagaagaa gataaagatt tttttggttg agagtgtggg6001 tcttgcatta catcaaacag agttcaaatt ccacacagat aagaggcagg atatataagc6061 gccagtggta gttgggagga ataaaccatt atttggatgc aggtggtttt tgattgcaaa6121 tatgtgtgtg tcttcagtga ttgtatgaca gatgatgtat tcttttgatg ttaaaagatt6181 ttaagtaaga gtagatacat tgtacccatt ttacattttc ttattttaac tacagtaatc6241 tacataaata tacctcagaa atcatttttg gtgattattt tttgttttgt agaattgcac6301 ttcagtttat tttcttacaa ataaccttac attttgttta atggcttcca agagcctttt6361 tttttttgta tttcagagaa aattcaggta ccaggatgca atggatttat ttgattcagg6421 ggacctgtat ttccatgtca aatgttttca aataaaatga aatatgagtt tcaatacttt6481 ttatatttta atatttcctt aatattatgg ttattgtccg ccattttgtt gtatattgta6541 aataaagttt agattgt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>65<211>1559<212>DNA<213>人類(Homo sapiens)<400>651 aaagaaccag ttttcaggcg gattgcctca gatcacacta tctccacttg cccagccctg61 tggaagatta gcggccatgt attccaatgt gataggaact gtaacctctg gaaaaaggaa121 ggtttatctt ttgtccttgc tgctcattgg cttctgggac tgcgtgacct gtcacgggag181 ccctgtggac atctgcacag ccaagccgcg ggacattccc atgaatccca tgtgcattta241 ccgctccccg gagaagaagg caactgagga tgagggctca gaacagaaga tcccggaggc301 caccaaccgg cgtgtctggg aactgtccaa ggccaattcc cgctttgcta ccactttcta361 tcagcacctg gcagattcca agaatgacaa tgataacatt ttcctgtcac ccctgagtat421 ctccacggct tttgctatga ccaagctggg tgcctgtaat gacaccctcc agcaactgat481 ggaggtattt aagtttgaca ccatatctga gaaaacatct gatcagatcc acttcttctt541 tgccaaactg aactgccgac tctatcgaaa agccaacaaa tcctccaagt tagtatcagc601 caatcgcctt tttggagaca aatcccttac cttcaatgag acctaccagg acatcagtga661 gttggtatat ggagccaagc tccagcccct ggacttcaag gaaaatgcag agcaatccag721 agcggccatc aacaaatggg tgtccaataa gaccgaaggc cgaatcaccg atgtcattcc781 ctcggaagcc atcaatgagc tcactgttct ggtgctggtt aacaccattt acttcaaggg841 cctgtggaag tcaaagttca gccctgagaa cacaaggaag gaactgttct acaaggctga901 tggagagtcg tgttcagcat ctatgatgta ccaggaaggc aagttccgtt atcggcgcgt961 ggctgaaggc acccaggtgc ttgagttgcc cttcaaaggt gatgacatca ccatggtcct1021 catcttgccc aagcctgaga agagcctggc caaggtagag aaggaactca ccccagaggt1081 gctgcaagag tggctggatg aattggagga gatgatgctg gtggtccaca tgccccgctt1141 ccgcattgag gacggcttca gtttgaagga gcagctgcaa gacatgggcc ttgtcgatct1201 gttcagccct gaaaagtcca aactcccagg tattgttgca gaaggccgag atgacctcta1261 tgtctcagat gcattccata aggcatttct tgaggtaaat gaagaaggca gtgaagcagc1321 tgcaagtacc gctgttgtga ttgctggccg ttcgctaaac cccaacaggg tgactttcaa
1381 ggccaacagg cctttcctgg tttttataag agaagttcct ctgaacacta ttatcttcat1441 gggcagagta gccaaccctt gtgttaagta aaatgttctt attctttgca cctcttccta1501 tttttggttt gtgaacagaa gtaaaaataa atacaaacta cttccatctc acattaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>66<211>1502<212>DNA<213>人類(Homo sapiens)<400>661 cagggacaca gtactcggcc acaccatggg gcgcccactg cacctcgtcc tgctcagtgc61 ctccctggct ggcctcctgc tgctcgggga aagtctgttc atccgcaggg agcaggccaa121 caacatcctg gcgagggtca cgagggccaa ttcctttctt gaagagatga agaaaggaca181 cctcgaaaga gagtgcatgg aagagacctg ctcatacgaa gaggcccgcg aggtctttga241 ggacagcgac aagacgaatg aattctggaa taaatacaaa gatggcgacc agtgtgagac301 cagtccttgc cagaaccagg gcaaatgtaa agacggcctc ggggaataca cctgcacctg361 tttagaagga ttcgaaggca aaaactgtga attattcaca cggaagctct gcagcctgga421 caacggggac tgtgaccagt tctgccacga ggaacagaac tctgtggtgt gctcctgcgc481 ccgcgggtac accctggctg acaacggcaa ggcctgcatt cccacagggc cctacccctg541 tgggaaacag accctggaac gcaggaagag gtcagtggcc caggccacca gcagcagcgg601 ggaggcccct gacagcatca catggaagcc atatgatgca gccgacctgg accccaccga661 gaaccccttc gacctgcttg acttcaacca gacgcagcct gagaggggcg acaacaacct721 caccaggatc gtgggaggcc aggaatgcaa ggacggggag tgtccctggc aggccctgct781 catcaatgag gaaaacgagg gtttctgtgg tggaaccatt ctgagcgagt tctacatcct841 aacggcagcc cactgtctct accaagccaa gagattcaag gtgagggtag gggaccggaa901 cacggagcag gaggagggcg gtgaggcggt gcacgaggtg gaggtggtca tcaagcacaa961 ccggttcaca aaggagacct atgacttcga catcgccgtg ctccggctca agacccccat1021 caccttccgc atgaacgtgg cgcctgcctg cctccccgag cgtgactggg ccgagtccac1081 gctgatgacg cagaagacgg ggattgtgag cggcttcggg cgcacccacg agaagggccg1141 gcagtccacc aggctcaaga tgctggaggt gccctacgtg gaccgcaaca gctgcaagct1201 gtccagcagc ttcatcatca cccagaacat gttctgtgcc ggctacgaca ccaagcagga1261 ggatgcctgc cagggggaca gcgggggccc gcacgtcacc cgcttcaagg acacctactt1321 cgtgacaggc atcgtcagct ggggagaggg ctgtgcccgt aaggggaagt acgggatcta1381 caccaaggtc accgccttcc tcaagtggat cgacaggtcc atgaaaacca ggggcttgcc1441 caaggccaag agccatgccc cggaggtcat aacgtcctct ccattaaagt gagatcccac1501 tc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>67<211>1997<212>DNA<213>人類(Homo sapiens)<400>671 aattcctcag tgacccagga gctgacacac tatggcgcac gtccgaggct tgcagctgcc
61 tggctgcctg gccctggctg ccctgtgtag ccttgtgcac agccagcatg tgttcctggc121 tcctcagcaa gcacggtcgc tgctccagcg ggtccggcga gccaacacct tcttggagga181 ggtgcgcaag ggcaacctag agcgagagtg cgtggaggag acgtgcagct acgaggaggc241 cttcgaggct ctggagtcct ccacggctac ggatgtgttc tgggccaagt acacagcttg301 tgagacagcg aggacgcctc gagataagct tgctgcatgt ctggaaggta actgtgctga361 gggtctgggt acgaactacc gagggcatgt gaacatcacc cggtcaggca ttgagtgcca421 gctatggagg agtcgctacc cacataagcc tgaaatcaac tccactaccc atcctggggc481 cgacctacag gagaatttct gccgcaaccc cgacagcagc accacgggac cctggtgcta541 cactacagac cccaccgtga ggaggcagga atgcagcatc cctgtctgtg gccaggatca601 agtcactgta gcgatgactc cacgctccga aggctccagt gtgaatctgt cacctccatt661 ggagcagtgt gtccctgatc gggggcagca gtaccagggg cgcctggcgg tgaccacaca721 tgggctcccc tgcctggcct gggccagcgc acaggccaag gccctgagca agcaccagga781 cttcaactca gctgtgcagc tggtggagaa cttctgccgc aacccagacg gggatgagga841 gggcgtgtgg tgctatgtgg ccgggaagcc tggcgacttt gggtactgcg acctcaacta901 ttgtgaggag gccgtggagg aggagacagg agatgggctg gatgaggact cagacagggc961 catcgaaggg cgtaccgcca ccagtgagta ccagactttc ttcaatccga ggacctttgg1021 ctcgggagag gcagactgtg ggctgcgacc tctgttcgag aagaagtcgc tggaggacaa1081 aaccgaaaga gagctcctgg aatcctacat cgacgggcgc attgtggagg gctcggatgc1141 agagatcggc atgtcacctt ggcaggtgat gcttttccgg aagagtcccc aggagctgct1201 gtgtggggcc agcctcatca gtgaccgctg ggtcctcacc gccgcccact gcctcctgta1261 cccgccctgg gacaagaact tcaccgagaa tgaccttctg gtgcgcattg gcaagcactc1321 ccgcacaagg tacgagcgaa acattgaaaa gatatccatg ttggaaaaga tctacatcca1381 ccccaggtac aactggcggg agaacctgga ccgggacatt gccctgatga agctgaagaa1441 gcctgttgcc ttcagtgact acattcaccc tgtgtgtctg cccgacaggg agacggcagc1501 cagcttgctc caggctggat acaaggggcg ggtgacaggc tggggcaacc tgaaggagac1561 gtggacagcc aacgttggta aggggcagcc cagtgtcctg caggtggtga acctgcccat1621 tgtggagcgg ccggtctgca aggactccac ccggatccgc atcactgaca acatgttctg1681 tgctggttac aagcctgatg aagggaaacg aggggatgcc tgtgaaggtg acagtggggg1741 accctttgtc atgaagagcc cctttaacaa ccgctggtat caaatgggca tcgtctcatg1801 gggtgaaggc tgtgaccggg atgggaaata tggcttctac acacatgtgt tccgcctgaa1861 gaagtggata cagaaggtca ttgatcagtt tggagagtag gggccactca tattctgggc1921 tcctggaacc aatcccgtga aagaattatt tttgtgtttc taaaactatg gttcccaata1981 aaagtgactc tcagcgg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>68<211>3655<212>DNA<213>人類(Homo sapiens)<400>681 agcaatcctt tctttcagct ggagtgctcc tcaggagcca gccccaccct tagaaaagat61 gttttccatg aggatcgtct gcctggtcct aagtgtggtg ggcacagcat ggactgcaga121 tagtggtgaa ggtgactttc tagctgaagg aggaggcgtg cgtggcccaa gggttgtgga181 aagacatcaa tctgcctgca aagattcaga ctggcccttc tgctctgatg aagactggaa241 ctacaaatgc ccttctggct gcaggatgaa agggttgatt gatgaagtca atcaagattt301 tacaaacaga ataaataagc tcaaaaattc actatttgaa tatcagaaga acaataagga
36l ttctcattcg ttgaccacta atataatgga aattttgaga ggcgattttt cctcagcaaa42l taaccgtgat aatacctaca accgagtgtc agaggatctg agaagcagaa ttgaagtcct48l gaagcgcaaa gtcatagaaa aagtacagca tatccagctt ctgcagaaaa atgttagagc54l tcagttggtt gatatgaaac gactggaggt ggacattgat attaagatcc gatcttgtcg60l agggtcatgc agtagggctt tagctcgtga agtagatctg aaggactatg aagatcagca66l gaagcaactt gaacaggtca ttgccaaaga cttacttccc tctagagata ggcaacactt721 accactgata aaaatgaaac cagttccaga cttggttccc ggaaatttta agagccagct781 tcagaaggta cccccagagt ggaaggcatt aacagacatg ccgcagatga gaatggagtt84l agagagacct ggtggaaatg agattactcg aggaggctcc acctcttatg gaaccggatc90l agagacggaa agccccagga accctagcag tgctggaagc tggaactctg ggagctctgg961 acctggaagt actggaaacc gaaaccctgg gagctctggg actggaggga ctgcaacctg102l gaaacctggg agctctggac ctggaagtac tggaagctgg aactctggga gctctggaac1081 tggaagtact ggaaaccaaa accctgggag ccctagacct ggtagtaccg gaacctggaal14l tcctggcagc tctgaacgcg gaagtgctgg gcactggacc tctgagagct ctgtatctgg1201 tagtactgga caatggcact ctgaatctgg aagttttagg ccagatagcc caggctctgg1261 gaacgcgagg cctaacaacc cagactgggg cacatttgaa gaggtgtcag gaaatgtaag132l tccagggaca aggagagagt accacacaga aaaactggtc acttctaaag gagataaaga138l gctcaggact ggtaaagaga aggtcacctc tggtagcaca accaccacgc gtcgttcatg1441 ctctaaaacc gttactaaga ctgttattgg tcctgatggt cacaaagaag ttaccaaaga150l agtggtgacc tccgaagatg gttctgactg tcccgaggca atggatttag gcacattgtc1561 tggcataggt actctggatg ggttccgcca taggcaccct gatgaagctg ccttcttcga162l cactgcctca actggaaaaa cattcccagg tttcttctca cctatgttag gagagtttgt168l cagtgagact gagtctaggg gctcagaatc tggcatcttc acaaatacaa aggaatccag1741 ttctcatcac cctgggatag ctgaattccc ttcccgtggt aaatcttcaa gttacagcaa1801 acaatttact agtagcacga gttacaacag aggagactcc acatttgaaa gcaagagcta1861 taaaatggca gatgaggccg gaagtgaagc cgatcatgaa ggaacacata gcaccaagag192l aggccatgct aaatctcgcc ctgtcagaga ctgtgatgat gtcctccaaa cacatccttc198l aggtacccaa agtggcattt tcaatatcaa gctaccggga tccagtaaga ttttttctgt2041 ttattgcgat caagagacca gtttgggagg atggcttttg atccagcaaa gaatggatgg210l atcactgaat tttaaccgga cctggcaaga ctacaagaga ggtttcggca gcctgaatga216l cgagggggaa ggagaattct ggctaggcaa tgactacctc cacttactaa cccaaagggg222l ctctgttctt agggttgaat tagaggactg ggctgggaat gaagcttatg cagaatatca228l cttccgggta ggctctgagg ctgaaggcta tgccctccaa gtctcctcct atgaaggcac234l tgcgggtgat gctctgattg agggttccgt agaggaaggg gcagagtaca cctctcacaa240l caacatgcag ttcagcacct ttgacaggga tgcagaccag tgggaagaga actgtgcaga2461 agtctatggg ggaggctggt ggtataataa ctgccaagca gccaatctca atggaatcta2521 ctaccctggg ggctcctatg acccaaggaa taacagtcct tatgagattg agaatggagt258l ggtctgggtt tcctttagag gggcagatta ttccctcagg gctgttcgca tgaaaattag264l gccccttgtg acccaatagg ctgaagaagt gggaatggga gcactctgtc ttctttgcta2701 gagaagtgga gagaaaatac aaaaggtaaa gcagttgaga ttctctacaa cctaaaaaat2761 tcctaggtgc tattttctta tcctttgtac tgtagctaaa tgtacctgag acatattagt2821 ctttgaaaaa taaagttatg taaggttttt tttatcttta aatagctctg tgggttttaa2881 catttttata aagatatacc aagggccatt cagtacatca ggaaagtggc agacagaagc2941 ttctctctgc aaccttgaag actattggtt tgagaacttc tcttcccata ccacccaaaa3001 tcataatgcc attggaaagc aaaaagttgt tttatccatt tgatttgaat tgttttaagc306l caatatttta aggtaaaact cactgaatct aaccatagct gacctttgta gtagaattta312l caacttataa ttacaatgca caatttataa ttacaatatg tatttatgtc ttttgctatg3181 gagcaaatcc aggaaggcaa gagaaacatt ctttcctaaa tataaatgaa aatctatcct
3241 ttaaactctt ccactagacg ttgtaatgca cacttatttt tttcccaagg agtaaccaat3301 ttctttctaa aacacattta aaattttaaa actatttatg aatattaaaa aaagacataa3361 ttcacacatt aataaacaat ctcccaagta ttgatttaac ttcatttttc taataatcat3421 aaactatatt ctgtgacatg ctaattatta ttaaatgtaa gtcgttagtt cgaaagcctc3481 tcactaagta tgatctatgc tatattcaaa attcaaccca tttactttgg tcaatatttg3541 atctaagttg catctttaat cctggtggtc ttgccttctg atttttaatt tgtatccttt3601 tctattaaga tatatttgtc attttctctt gaatatgtat taaaatatcc caagc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>69<211>7633<212>DNA<213>人類(Homo sapiens)<400>691 gggccggggg gcggagcctt gcgggctgga gcgaaagaat gcgggggctg agcgcagaag61 cggctcgagg ctggaagagg atcttgggcg ccgccaggtt ctgtggacaa tcacaatggg121 aatccaagga gggtctgtcc tgttcgggct gctgctcgtc ctggctgtct tctgccattc181 aggtcatagc ctgcagtgct acaactgtcc taacccaact gctgactgca aaacagccgt241 caattgttca tctgattttg atgcgtgtct cattaccaaa gctgggttac aagtgtataa301 caagtgttgg aagtttgagc attgcaattt caacgacgtc acaacccgct tgagggaaaa361 tgagctaacg tactactgct gcaagaagga cctgtgtaac tttaacgaac agcttgaaaa421 tggtgggaca tccttatcag agaaaacagt tcttctgctg gtgactccat ttctggcagc481 agcctggagc cttcatccct aagtcaacac caggagagct tctcccaaac tccccgttcc541 tgcgtagtcc gctttctctt gctgccacat tctaaaggct tgatattttc caaatggatc601 ctgttgggaa agaataaaat tagcttgagc aacctggcta agatagaggg gctctgggag661 actttgaaga ccagtcctgt ttgcagggaa gccccacttg aaggaagaag tctaagagtg721 aagtaggtgt gacttgaact agattgcatg cttcctcctt tgctcttggg aagaccagct781 ttgcagtgac agcttgagtg ggttctctgc agccctcaga ttatttttcc tctggctcct841 tggatgtagt cagttagcat cattagtaca tctttggagg gtggggcagg agtatatgag901 catcctctct cacatggaac gctttcataa acttcaggga tcccgtgttg ccatggaggc961 atgccaaatg ttccatatgt gggtgtcagt cagggacaac aagatcctta atgcagagct1021 agaggacttc tggcagggaa gtggggaagt gttccagata gcagggcatg aaaacttaga1081 gaggtacaag tggctgaaaa tcgagttttt cctctgtctt taaattttat atgggctttg1141 ttatcttcca ctggaaaagt gtaatagcat acatcaatgg tgtgttaaag ctatttcctt1201 gccttttttt tattggaatg gtaggatatc ttggctttgc cacacacagt tacagagtga1261 acactctact acatgtgact ggcagtatta agtgtgctta ttttaaatgt tactggtaga1321 aaggcagttc aggtatgtgt gtatatagta tgaatgcagt ggggacaccc tttgtggtta1381 cagtttgaga cttccaaagg tcatccttaa taacaacaga tctgcagggg tatgttttac1441 catctgcatc cagcctcctg ctaactccta gctgactcag catagattgt ataaaatacc1501 tttgtaacgg ctcttagcac actcacagat gtttgaggct ttcagaagct cttctaaaaa1561 atgatacaca cctttcacaa gggcaaactt tttccttttc cctgtgtatt ctagtgaatg1621 aatctcaaga ttcagtagac ctaatgacat ttgtatttta tgatcttggc tgtatttaat1681 ggcataggct gacttttgca gatggaggaa tttcttgatt aatgttgaaa aaaaaccctt1741 gattatactc tgttggacaa accgagtgca atgaatgatg cttttctgaa aatgaaatat1801 aacaagtggg tgaatgtggt tatggccgaa aaggatatgc agtatgctta atggtagcaa1861 ctgaaagaag acatcctgag cagtgccagc tttcttctgt tgatgccgtt ccctgaacat
1921 aggaaaatag aaacttgctt atcaaaactt agcattacct tggtgctctg tgttctctgt1981 tagctcagtg tctttcctta catcaatagg tttttttttt tttttttggc ctgaggaagt2041 actgaccatg cccacagcca ccggctgagc aaagaagctc atttcatgtg agttctaagg2101 aatgagaaac aattttgatg aatttaagca gaaaatgaat ttctgggaac ttttttgggg2161 gcggggggtt ggggaattca gccacactcc agaaagccag gagtcgacag ttttggaagc2221 ctctctcagg attgagattc taggatgaga ttggcttact gctatcttgt gtcatgtacc2281 cactttttgg ccagactaca ctgggaagaa ggtagtcctc taaagcaaaa tctgagtgcc2341 actaaatggg gagatggggc tgttaagctg tccaaatcaa caagggtcat ataaatggcc2401 ttaaactttg gggttgcttt ctgcaaaaag ttgctgtgac tcatgccata gacaaggttg2461 agtgcctgga cccaaaggca atactgtaat gtaaagacat ttatagtact aggcaaacag2521 caccccaggt actccaggcc ctcctggctg gagagggctg tggcaataga aaattagtgc2581 caactgcagt gagtcagcct aggttaaata gagagtgtaa gagtgctgga caggaacctc2641 caccctcatg tcacatttct tcaatgtgac ccttctggcc cctctcctcc tgacagcgga2701 acaatgactg ccccgatagg tgaggctgga ggaagaatca gtcctgtcct tggcaagctc2761 ttcactatga cagtaaaggc tctctgcctg ctgccaaggc ctgtgacttt ctaacctggc2821 ctcacgctgg gtaagcttaa ggtagaggtg caggattagc aagcccacct ggctaccagg2881 ccgacagcta catcctccaa ctgaccctga tcaacgaaga gggattcatg tgtctgtctc2941 agttggttcc aaatgaaacc agggagcagg ggagttagga atcgaacacc agtcatgcct3001 actggctctc tgctcgagag ccaataccct gtgccctcca ctcatctgga tttacaggaa3061 ctgtcatagt gttcagtatt gggtggtgat aagcccattg gattgtcccc ttggggggat3121 gagctagggg tgcaaggaac acctgatgag tagataagtg gagctcatgg tatttcctga3181 aagatgctaa tctatttgcc aaacttggtc ttgaatgtac tgggggcttc aaggtatggg3241 tatatttttc ttgtgtcctt gcagttagcc cccatgtctt atgtgtgtcc tgaaaaaata3301 agagcctgcc caagactttg ggcctcttga cagaattaac cacttttata catctgagtt3361 ctcttggtaa gttctttagc agtgttcaaa gtctactagc tcgcattagt ttctgttgct3421 gccaacagat ctgaactaat gctaacagat ccccctgagg gattcttgat gggctgagca3481 gctggctgga gctagtactg actgacattc attgtgatga gggcagcttt ctggtacagg3541 attctaagct ctatgtttta tatacatttt catctgtact tgcacctcac tttacacaag3601 aggaaactat gcaaagttag ctggatcgct caaggtcact taggtaagtt ggcaagtcca3661 tgcttcccac tcagctcctc aggtcagcaa gtctacttct ctgcctattt tgtatactct3721 ctttaatatg tgcctagctt tggaaagtct agaatgggtc cctggtgcct ttttactttg3781 aagaaatcag tttctgcctc tttttggaaa agaaaacaaa gtgcaattgt tttttactgg3841 aaagttaccc aatagcatga ggtgaacagg acgtagttag gccttcctgt aaacagaaaa3901 tcatatcaaa acactatctt cccatctgtt tctcaatgcc tgctacttct tgtagatatt3961 tcatttcagg agagcagcag ttaaacccgt ggattttgta gttaggaacc tgggttcaaa4021 ccctcttcca ctaattggct atgtctctgg acaagttttt tttttttttt ttttttaaac4081 cctttctgaa ctttcacttt ctatgtctac ctcaaagaat tgttgtgagg cttgagataa4141 tgcatttgta aagggtctgc cagataggaa gatgctagtt atggatttac aaggttgtta4201 aggctgtaag agtctaaaac ctacagtgaa tcacaatgca tttaccccca ctgacttgga4261 cataagtgaa aactagccag aagtctcttt ttcaaattac ttacaggtta ttcaatataa4321 aatttttgta atggataatc ttatttatct aaactaaagc ttcctgttta tacacactcc4381 tgttattctg ggataagata aatgaccaca gtaccttaat ttctaggtgg gtgcctgtga4441 tggttcattg taggtaagga cattttctct ttttcagcag ctgtgtaggt ccagagcctc4501 tgggagagga ggggggtagc atgcacccag caggggactg aactgggaaa ctcaaggttc4561 tttttactgt ggggtagtga gctgcctttc tgtgatcggt ttccctaggg atgttgctgt4621 tcccctcctt gctattcgca gctacataca acgtggccaa ccccagtagg ctgatcctat4681 atatgatcag tgctggtgct gactctcaat agccccaccc aagctggcta taggtttaca4741 gatacattaa ttaggcaacc taaaatattg atgctggtgt tggtgtgaca taatgctatg
4801 gccagaactg aaacttagag ttataattca tgtattaggg ttctccagag ggacagaatt4861 agtaggatat atgtatatat gaaagggagg ttattaggga gaactggctc ccacagttag4921 aaggcgaagt cgcacaatag gccgtctgca agctgggtta gagagaagcc agtagtggct4981 cagcctgagt tcaaaaacct caaaactggg gaagctgaca gtgcagccag ccttcagtct5041 gtggccaaag gcccaagagc ccctggcaac caacccactg gtgcaagtcc tagattccaa5101 aggctgaaga acctggagtc tgatgtccaa gagcaggaag agtggaagaa agccagaaga5161 ctcagcaaac aaggtagaca gtgtctacca ccatagtggc cataccaaag aggctaccga5221 ttccttcctg ctacctggat ccctgaagtt gccctggtct ctgcaccttc taaacctagt5281 tcttaagagc tttccattac atgagctgtc tcaaagccct ccaataaatt ctcagtgtaa5341 gcttctgttg cttgtggaca gaaaattctg acagacctac cctataagtg ttactgtcag5401 gataacatga gaacgcacaa cagtaagtgg tcactaagtg ttagctacgg ttattttgcc5461 caaggtagca tggctagttg atgccggttg atggggctta aacccagctc cctcatcttc5521 caggcctctg tactccctat tccactaaac tacctctcag gtttattttt ttaaattctt5581 actctgcaag tacataggac cacatttacc tgggaaaaca agaataaagg ctgctctgca5641 ttttttagaa acttttttga aagggagatg ggaatgcctg cacccccaag tccagaccaa5701 cacaatggtt aattgagatg aataataaag gaaagactgt tctgggcttc ccagaatagc5761 ttggtcctta aattgtggca caaacaacct cctgtcagag ccagcctcct gccaggaaga5821 ggggtaggag actagaggcc gtgtgtgcag ccttgccctg aaggctaggg tgacaatttg5881 gaggctgtcc aaacaccctg gcctctagag ctggcctgtc tatttgaaat gccggctctg5941 atgctaatcg gcgaccctca ggcaagttac ttaaccttac atgcctcagt tttctcatct6001 ggaaaatgag aaccctaggt ttagggttgt tagaaaagtt aaatgagtta agacaagtgc6061 ctgggacaca gtagcctctt gtgtgtgttt atcattatgt cctcagcagg tcgtagaagc6121 agcttctcag gtgtgaggct ggcgcattat ctggagtggg ttgggttttc taggatggac6181 cccctgctgc attttcctca ttcatccacc agggcttaat ggggaatcaa ggaatccatg6241 tgtaactgta taataactgt agccacactc caatgaccac ctactagttg tccctggcac6301 tgcttataca tatgtccatc aaatcaatcc tatgaagtag atactgtctt cattttatag6361 atcagagaca attggggttc agagagctga tgtgattttc ccagggtcac agagagtccc6421 agattcaggc acaactcttg tattccaaga cacaaccact acatgtccaa aggctgccca6481 gagccaccgg gcacggcaaa ttgtgacata tccctaaaga ggctgagcac ctggtcagga6541 tctgatggct gacagtgtgt ccagatgcag agctggagtg ggggagggga aggggggctc6601 cttgggacag agaaggcttt ctgtgctttc tctgaaggga gcagtctgag gaccaaggga6661 acccggcaaa cagcacctca ggtactccag gccctcctgg ctggagaggg ctgtggcaat6721 ggaaaattag tgccaactgc aatgagtcag cctcggttaa atagagagtg aagaatgctg6781 gacaggaacc tccaccctca tgtcacattt cttcagtgtg acccttctgg cccctctcct6841 cctgacagcg gaacaatgac tgccccgata ggtgaggctg gaggaagaat cagtcctgtc6901 cttggcaagc tcttcactat gacagtaaag gctctctgcc tgctgccaag gcctgtgact6961 ttctaacctg gcctcacgct gggtaagctt aaggtagagg tgcaggatta gcaagcccac7021 ctggctacca ggccgacagc tacatctttc aactgaccct gatcaacgaa gagggacttg7081 tgtctctcag ttggttccaa atgaaaccag ggagcagggg cgttaggaag ctccaacagg7141 atggtactta atggggcatt tgagtggaga ggtaggtgac atagtgcttt ggagcccagg7201 gagggaaagg ttctgctgaa gttgaattca agactgttct ttcatcacaa acttgagttt7261 cctggacatt tgtttgcaga aacaaccgta gggttttgcc ttaacctcgt gggtttatta7321 ttacctcata gggactttgc ctcctgacag cagtttatgg gtgttcattg tggcacttga7381 gttttcttgc atacttgtta gagaaaccaa gtttgtcatc aacttcttat ttaaccccct7441 ggctataact tcatggatta tgttataatt aagccatcca gagtaaaatc tgtttagatt7501 atcttggagt aagggggaaa aaatctgtaa ttttttctcc tcaactagat atatacataa7561 aaaatgattg tattgcttca tttaaaaaat ataacgcaaa atctcttttc cttctaaaaa7621 aaaaaaaaaa aaa
<110>同濟大學附屬同濟醫(yī)院<12>肺血栓栓塞癥相關基因及其應用<160>142<210>70<211>1935<212>DNA<213>人類(Homo sapiens)<400>701 atctccgctg gttcccggaa gccgccgcgg acaagctctc ccgggcgcgg gcgggggtcg61 tgtgcttgga ggaagccgcg gaacccccag cgtccgtcca tggcgtggag ccttgggagc121 tggctgggtg gctgcctgct ggtgtcagca ttgggaatgg taccacctcc cgaaaatgtc181 agaatgaatt ctgttaattt caagaacatt ctacagtggg agtcacctgc ttttgccaaa241 gggaacctga ctttcacagc tcagtaccta agttatagga tattccaaga taaatgcatg301 aatactacct tgacggaatg tgatttctca agtctttcca agtatggtga ccacaccttg361 agagtcaggg ctgaatttgc agatgagcat tcagactggg taaacatcac cttctgtcct421 gtggatgaca ccattattgg accccctgga atgcaagtag aagtacttgc tgattcttta481 catatgcgtt tcttagcccc taaaattgag aatgaatacg aaacttggac tatgaagaat541 gtgtataact catggactta taatgtgcaa tactggaaaa acggtactga tgaaaagttt601 caaattactc cccagtatga ctttgaggtc ctcagaaacc tggagccatg gacaacttat661 tgtgttcaag ttcgagggtt tcttcctgat cggaacaaag ctggggaatg gagtgagcct721 gtctgtgagc aaacaaccca tgacgaaacg gtcccctcct ggatggtggc cgtcatcctc781 atggcctcgg tcttcatggt ctgcctggca ctcctcggct gcttcgcctt gctgtggtgc841 gtttacaaga agacaaagta cgccttctcc cctaggaatt ctcttccaca gcacctgaaa901 gagtttttgg gccatcctca tcataacaca cttctgtttt tctcctttcc attgtcggat961 gagaatgatg tttttgacaa gctaagtgtc attgcagaag actctgagag cggcaagcag1021 aatcctggtg acagctgcag cctcgggacc ccgcctgggc aggggcccca aagctaggct1081 ctgagaagga aacacactcg gctgggcaca gtgacgtact ccatctcaca tctgcctcag1141 tgagggatca gggcagcaaa caagggccaa gaccatctga gccagcccca catctagaac1201 tcccagaccc tggacttagc caccagagag ctacatttta aaggctgtct tggcaaaaat1261 actccatttg ggaactcact gccttataaa ggctttcatg atgttttcag aagttggcca1321 ctgagagtgt aattttcagc cttttatatc actaaaataa gatcatgttt taattgtgag1381 aaacagggcc gagcacagtg gctcacgcct gtaataccag caccttagag gtcgaggcag1441 gcggatcact tgaggtcagg agttcaagac cagcctggcc aatatggtga aacccagtct1501 ctactaaaaa tacaaaaatt agctaggcat gatggcgcat gcctataatc ccagctactc1561 gagtgcctga ggcaggagaa ttgcatgaac ccgggaggag gaggaggagg ttgcagtgag1621 ccgagatagc ggcactgcac tccagcctgg gtgacaaagt gagactccat ctcaaaaaaa1681 aaaaaaaaaa aaattgtgag aaacagaaat acttaaaatg aggaataaga atggagatgt1741 tacatctggt agatgtaaca ttctaccaga ttatggatgg actgatctga aaatcgacct1801 caactcaagg gtggtcagct caatgctaca cagagcacgg acttttggat tctttgcagt1861 actttgaatt tatttttcta cctatatatg ttttatatgc tgctggtgct ccattaaagt1921 tttactctgt gttgc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>71<211>1131
<212>DNA<213>人類(Homo sapiens)<400>711 attcccagaa accaggaaat ttctgaaact gagttttaaa cctggcaact cttttaccat61 ccctttgtat ttttgcagtt cctccctata ccagcttcct tacagctgtt ctgatttcct121 gtcgtaagat tttttctttt cattttctcc agggagggta aatcaatata acctcttctc181 tagagaggag gtggttaggt tggtcttaag cagtgttaga agatctattt tttttcaaac241 caggtgtctg agctgggtga attccagcct ggggagagga ctttgatcac cagatgtttt301 tttggtgtgc gtgctgtctt atggttgcgt ggcgagtttc tgcttcagat gcagagcact361 gtccagagct tcctccagtg gacaatagca tatttgtcgc aaaggaggtg gaaggacaga421 ttctggggac ttacgtttgt atcaagggct accacctggt aggaaagaag accctttttt481 gcaatgcctc taaggagtgg gataacacca ctactgagtg ccgcttgggc cactgtcctg541 atcctgtgct ggtgaatgga gagttcagtt cttcagggcc tgtgaatgta agtgacaaaa601 tcacgtttat gtgcaatgac cactacatcc tcaagggcag caatcggagc cagtgtctag661 aggaccacac ctgggcacct ccctttccca tctgcaaaag tagggactgt gaccctcctg721 ggaatccagt tcatggctat tttgaaggaa ataacttcac cttaggatcc accattagtt781 attactgtga agacaggtac tacttagtgg gcgtgcagga gcagcaatgc gttgatgggg841 agtggagcag tgcacttcca gtctgcaagt tgatccagga agctcccaaa ccagagtgtg901 agaaggcact tcttgccttt caggagagta agaacctctg cgaagccatg gagaacttta961 tgcaacaatt aaaggaaagt ggcatgacaa tggaggagct aaaatattct ctggagctga1021 agaaagctga gttgaaggca aaattgttgt aacactacag ctgagcagat gtaatagaaa1081 taaacctatg aataaatttt cttcttggtt ctgaaaaaaa aaaaaaaaaa a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>72<211>3948<212>DNA<213>人類(Homo sapiens)<400>721 ggcaagggac ggagaacggg gcggaggcgg agtcagggcg cccgcgcgtg ggccccgccc61 ccttatgtag ggtataaagc ccctcccgct cacagtttcc ctagtcctcg aaggctcgga121 agcccgtcac catgtcgtgc gagtcgtcta tggttctcgg gtactgggat attcgtgggc181 tggcgcacgc catccgcctg ctcctggagt tcacggatac ctcttatgag gagaaacggt241 acacgtgcgg ggaagctcct gactatgatc gaagccaatg gctggatgtg aaattcaagc301 tagacctgga ctttcctaat ctgccctacc tcctggatgg gaagaacaag atcacccaga361 gcaatgccat cttgcgctac atcgctcgca agcacaacat gtgtggtgag actgaagaag421 aaaagattcg agtggacatc atagagaacc aagtaatgga tttccgcaca caactgataa481 ggctctgtta cagctctgac cacgaaaaac tgaagcctca gtacttggaa gagctacctg541 gacaactgaa acaattctcc atgtttctgg ggaaattctc atggtttgcc ggggaaaagc601 tcacctttgt ggattttctc acctatgata tcttggatca gaaccgtata tttgacccca661 agtgcctgga tgagttccca aacctgaagg ctttcatgtg ccgttttgag gctttggaga721 aaatcgctgc ctacttacag tctgatcagt tctgcaagat gcccatcaac aacaagatgg781 cccagtgggg caacaagcct gtatgctgag caggaggcag acttgcagag cttgttttgt841 ttcatcctgt ccgtaagggg tcagcgctct tgctttgctc ttttcaatga atagcactta901 tgttactggt gtccagctga gtttctcttg ggtataaagg ctaaaaggga aaaaggatat961 gtggagaatc atcaagatat gaattgaatc gctgcgatac tggcatttcc ctactcccca
1021 actgagttca agggctgtag gttcatgccc aagccctgag agtgggtact agaaaaaacg1081 agattgcaca gttggagaga gcaggtgtgt taaatgggac tggagtccct gtgaagactg1141 ggtgaggata acacaagtaa aactgtggta ctgatggact taaccggagt tcggaaaccg1201 tcctgtgtac acatgggagt ttagtgtgat aaaggcagta tttcagactg gtgggctagc1261 caatagagtt gggacaattg cttactcatt aaaaataata gagccccact tgacactatt1321 cactaaaatt aatctggaat ttaaggccca acattaaaca caaagctgtt gaaatattga1381 tgaaaatgta agaatttttg tgaccacggg gtaggagaag tttctttaaa gacgtaaaaa1441 gaaaaaaacc ataggctgct ctgcctgtgg agtagccatt ctttattctt ttacttttta1501 aaataataac aatcacaaag gaaagatttg ccaattgaat aggatcaaat tctacaactt1561 ttcctaaggc acccacaaat aaatgacaag tgagacaaaa agcactagta taaagattat1621 ataaagacct ataaatcatt aagacaactg agtttttaaa aatggacaaa atccatgaac1681 aatttataaa atagaaatat agccaaaaat gtctaaaaga tgtttatgat gtaaggaatt1741 atcaattaca acagtgagaa accatatttc cttctatccg atgagtaaaa agtttctaaa1801 gtgttggcaa ggcttaggaa agtgatatgc atttcctgct ggtcaagttg taaattagta1861 tagctacttt ggaggacaat tgtaaaattt aaatcatatc ctatgaccca gcaattccat1921 gctataaaaa ctcatccatg gccgggcttg gtggctcacg cctgtaatcc cagcactttg1981 ggaggctgag gtgggcagat cacgaggtca agagatcgag accatcctgg ccaacatgat2041 gaaaccccgt ttctactaaa aatacaaaaa ttagctgggc atggtggcat gtgcctatag2101 tcccagctac tcaggaggct gaggcaggag aattgcttga acctgggagg cagaggttgc2161 agtgagccga gatcacgcca ctgcactcca gcctggctac agggcgagac tctgtctcaa2221 aaaaaaaaaa aaaaaaaaaa aaaaaacatt caaagagaca tatactaaga tgttcactgt2281 ggcattgtct gtaatgacaa ataagtggaa accgtgtaaa tacctgtcaa tactatggag2341 taccatgtgg caacggaaga atgagactga actgtgtgaa ctaacatgca aagatcccca2401 aaacaggcca ggtgtggttg ctcacagctg taataacaac accttcagag gctgaggtga2461 gaggatcagt tgaggccagg agtttaagac cagcctgggc aacatagtga gacccctgtc2521 tcccaaaaat tttttttaat tagctgtgcg caattgctca tgcatagtcc cagctaccca2581 ggaggctgag gtgggaggat cacttgagcc caggaatttg aagctgcagt gagctgtgtt2641 cttgccactg cactccaatc tgggtgactg agcaagaccc tgtctcttaa aaaaataaaa2701 aagatctcca agcatagaga agagtctgga gggaaacacc aaactcataa cagtcttact2761 gcaggcaagt gggataaagg cccagactcc atggtggaag ttaaagggca tttccaagtt2821 aaggctaaga cttgcttttc taactaagag aatgtgctca tgcattgctt gtgtagtaga2881 aactagtttt tagaaaagaa agcaaactta agaaacactg actcctgtgg agatgacttg2941 gcaccactct cctttcacag agcagagtct gaatagtctt cagagatagg cctgtgggcc3001 agattgccat cccctatgga ccagaagcca aggatctctc tagtgatggt cagagggccc3061 aaatggcagg gatacccagt gatgtcagga ggaatagtac agacagaagg tgctaagcag3121 acaattcaac tgccatgttt tgccaccccc tgtgagcagg gattaggtgt tcaggccagt3181 atcttgggca tgggggagcc tttggccaga agaggtataa agctcagaag tttttcagtc3241 tgataactat tgatataatt tccatagtgt gagggagcgg tatgctctac ccttgtgtat3301 ttaaggcagg acagagaaat tgaggatgcc cctggggcta gatcgatgat atgaccagaa3361 atcaaaaagg gaatgcatta tttattgctg tgtaacactg ttaagagagg aggtagttaa3421 gggatggata ggcacataga gagggaaggt ctcaggagaa gggatagaaa ggaactatgt3481 tcacaagaac aacggcaaga cagtgcctat actgcctcta cagttaatag gaaaaacgga3541 agaagttacc cttaagctag gatgttgctc agaagtgacc atcccaactt tggtgcgggc3601 acaataaatc agcctaaatg tccctaattt aacccagctc attataatgt cattaaacat3661 gacattagca ttgtggtttt agcaccccca tgggttttgc ttaggcactc atgggtaata3721 accaagatgg agtccctttg gcaaaactta ggcatgcaca gctgtagtac cccaagaaga3781 aaatgttact tctctcatct gggcaaaacc cacagaagac ttcccagctt ctgccacata3841 aaagacacag aacacagacg ccttactggc aacctgcttt caagacccct gtctttgctg
3901 agagctttcc tttttcccaa taaattctac tctgccctac tcactctc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>73<211>3015<212>DNA<213>人類(Homo sapiens)<400>731 cccttatggc gattgggcgg ctgcagagac caggactcag ttcccctgcc ctagtctgag61 cctagtgggt gggactcagc tcagagtcag ttttccagaa gcaggtttca gtgcagagtt121 ttcctacact tttcctgcgc tagagcagcg agcagcctgg aacagaccca ggcggaggac181 acctgtgggg gagggagcgc ctggaggagc ttagagaccc cagccgggcg tgatctcacc241 atgtgcggat ttgcgaggcg cgccctggag ctgctagaga tccggaagca cagccccgag301 gtgtgcgaag ccaccaagac tgcggctctt ggagaaagcg tgagcagggg gccaccgcgg361 tctccgcgcc tgtctgcacc ctgtcgcctg agctgcctga cagtgacaat gacatcccag421 ttaccagtgt ccttgaattg atagtggctt ctgtttgtca gtctcatata agaactacag481 ctcatcagga ggagatcgca gcagggtaag agacaccaac accatgttct gcacgaagct541 caaggatctc aagatcacag gagagtgtcc tttctcctta ctggcaccag gtcaagttcc601 taacgagtct tcagaggagg cagcaggaag ctcagagagc tgcaaagcaa ccgtgcccat661 ctgtcaagac attcctgaga agaacataca agaaagtctt cctcaaagaa aaaccagtcg721 gagccgagtc tatcttcaca ctttggcaga gagtatttgc aaactgattt tcccagagtt781 tgaacggctg aatgttgcac ttcagagaac attggcaaag cacaaaataa aagaaagcag841 gaaatctttg gaaagagaag actttgaaaa aacaattgca gagcaagcag ttgcagcagg901 agttccagtg gaggttatca aagaatctct tggtgaagag gtttttaaaa tatgttacga961 ggaagatgaa aacatccttg gggtggttgg aggcaccctt aaagattttt taaacagctt1021 cagtaccctt ctgaaacaga gcagccattg ccaagaagca ggaaaaaggg gcaggcttga1081 ggacgcctcc attctatgcc tggataagga ggatgatttt ctacatgttt actacttctt1141 ccctaagaga accacctccc tgattcttcc cggcatcata aaggcagctg ctcacgtatt1201 atatgaaacg gaagtggaag tgtcgttaat gcctccctgc ttccataatg attgcagcga1261 gtttgtgaat cagccctact tgttgtactc cgttcacatg aaaagcacca agccatccct1321 gtcccccagc aaaccccagt cctcgctggt gattcccaca tcgctattct gcaagacatt1381 tccattccat ttcatgtttg acaaagatat gacaattctg caatttggca atggcatcag1441 aaggctgatg aacaggagag actttcaagg aaagcctaat tttgaagaat actttgaaat1501 tctgactcca aaaatcaacc agacgtttag cgggatcatg actatgttga atatgcagtt1561 tgttgtacga gtgaggagat gggacaactc tgtgaagaaa tcttcaaggg ttatggacct1621 caaaggccaa atgatctaca ttgttgaatc cagtgcaatc ttgtttttgg ggtcaccctg1681 tgtggacaga ttagaagatt ttacaggacg agggctctac ctctcagaca tcccaattca1741 caatgcactg agggatgtgg tcttaatagg ggaacaagcc cgagctcaag atggcctgaa1801 gaagaggctg gggaagctga aggctaccct tgagcaagcc caccaagccc tggaggagga1861 gaagaaaaag acagtagacc ttctgtgctc catatttccc tgtgaggttg ctcagcagct1921 gtggcaaggg caagttgtgc aagccaagaa gttcagtaat gtcaccatgc tcttctcaga1981 catcgttggg ttcactgcca tctgctccca gtgctcaccg ctgcaggtca tcaccatgct2041 caatgcactg tacactcgct tcgaccagca gtgtggagag ctggatgtct acaaggtgga2101 gaccattggc gatgcctatt gtgtagctgg gggattacac aaagagagtg atactcatgc2161 tgttcagata gcgctgatgg ccctgaagat gatggagctc tctgatgaag ttatgtctcc2221 ccatggagaa cctatcaaga tgcgaattgg actgcactct ggatcagttt ttgctggcgt
2281 cgttggagtt aaaatgcccc gttactgtct ttttggaaac aatgtcactc tggctaacaa2341 atttgagtcc tgcagtgtac cacgaaaaat caatgtcagc ccaacaactt acagattact2401 caaagactgt cctggtttcg tgtttacccc tcgatcaagg gaggaacttc caccaaactt2461 ccctagtgaa atccccggaa tctgccattt tctggatgct taccaacaag gaacaaactc2521 aaaaccatgc ttccaaaaga aagatgtgga agatggcaat gccaattttt taggcaaagc2581 atcaggaata gattagcaac ctatatacct atttataagt ctttggggtt tgactcattg2641 aagatgtgta gagcctctga aagcacttta gggattgtag atggctaaca agcagtatta2701 aaatttcagg agccaagtca caatctttct cctgtttaac atgacaaaat gtactcactt2761 cagtacttca gctcttcaag aaaaaaaaaa aaaccttaaa aagctacttt tgtgggagta2821 tttctattat ataaccagca cttactacct gtactcaaaa ttcagcacct tgtacatata2881 tcagataatt gtagtcaatt gtacaaactg atggagtcac ctgcaatctc atatcctggt2941 ggaatgccat ggttattaaa gtgtgtttgt gatagtgtcg tcaaaaaaaa aaaaaaaaaa3001 aaaaaaaaaa aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>74<211>2245<212>DNA<213>人類(Homo sapiens)<400>741 agaacagctt gaagaccgtt catttttaag tgacaagaga ctcacctcca agaagcaatt61 gtgttttcag aatgatttta ttcaagcaag caacttattt catttccttg tttgctacag121 tttcctgtgg atgtctgact caactctatg aaaacgcctt cttcagaggt ggggatgtag181 cttccatgta caccccaaat gcccaatact gccagatgag gtgcacattc cacccaaggt241 gtttgctatt cagttttctt ccagcaagtt caatcaatga catggagaaa aggtttggtt301 gcttcttgaa agatagtgtt acaggaaccc tgccaaaagt acatcgaaca ggtgcagttt361 ctggacattc cttgaagcaa tgtggtcatc aaataagtgc ttgccatcga gacatttata421 aaggagttga tatgagagga gtcaatttta atgtgtctaa ggttagcagt gttgaagaat481 gccaaaaaag gtgcaccaat aacattcgct gccagttttt ttcatatgcc acgcaaacat541 ttcacaaggc agagtaccgg aacaattgcc tattaaagta cagtcccgga ggaacaccta601 ccgctataaa ggtgctgagt aacgtggaat ctggattctc actgaagccc tgtgcccttt661 cagaaattgg ttgccacatg aacatcttcc agcatcttgc gttctcagat gtggatgttg721 ccagggttct cactccagat gcttttgtgt gtcggaccat ctgcacctat caccccaact781 gcctcttctt tacattctat acaaatgtat ggaaaatcga gtcacaaaga aatgtttgtc841 ttcttaaaac atctgaaagt ggcacaccaa gttcctctac tcctcaagaa aacaccatat901 ctggatatag ccttttaacc tgcaaaagaa ctttacctga accctgccat tctaaaattt961 acccgggagt tgactttgga ggagaagaat tgaatgtgac ttttgttaaa ggagtgaatg1021 tttgccaaga gacttgcaca aagatgattc gctgtcagtt tttcacttat tctttactcc1081 cagaagactg taaggaagag aagtgtaagt gtttcttaag attatctatg gatggttctc1141 caactaggat tgcgtatggg acacaaggga gctctggtta ctctttgaga ttgtgtaaca1201 ctggggacaa ctctgtctgc acaacaaaaa caagcacacg cattgttgga ggaacaaact1261 cttcttgggg agagtggccc tggcaggtga gcctgcaggt gaagctgaca gctcagaggc1321 acctgtgtgg agggtcactc ataggacacc agtgggtcct cactgctgcc cactgctttg1381 atgggcttcc cctgcaggat gtttggcgca tctatagtgg cattttaaat ctgtcagaca1441 ttacaaaaga tacacctttc tcacaaataa aagagattat tattcaccaa aactataaag1501 tctcagaagg gaatcatgat atcgccttga taaaactcca ggctcctttg aattacactg
1561 aattccaaaa accaatatgc ctaccttcca aaggtgacac aagcacaatt tataccaact1621 gttgggtaac cggatggggc ttctcgaagg agaaaggtga aatccaaaat attctacaaa1681 aggtaaatat tcctttggta acaaatgaag aatgccagaa aagatatcaa gattataaaa1741 taacccaacg gatggtctgt gctggctata aagaaggggg aaaagatgct tgtaagggag1801 attcaggtgg tcccttagtt tgcaaacaca acggaatgtg gcgtttggtg ggcatcacaa1861 gctggggtga aggctgtgcc cgcagggagc aacctggtgt ctacaccaaa gtcgctgagt1921 acatggactg gattttagag aaaacacaga gcagtgatgg aaaagctcag atgcagtcac1981 cagcatgaga agcagtccag agtctaggca atttttacaa cctgagttca agtcaaattc2041 tgagcctggg gggtcctcat ctgcaaagca tggagagtgg catcttcttt gcatcctaag2101 gacgaaagac acagtgcact cagagctgct gaggacaatg tctgctgaag cccgctttca2161 gcacgccgta accaggggct gacaatgcga ggtcgcaact gagatctcca tgactgtgtg2221 ttgtgaaata aaatggtgaa agatc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>75<211>1668<212>DNA<213>人類(Homo sapiens)<400>751 aaatatgttt ggataaccca gcagagccat ttaacctttg ggaacaaggc aactagcgtc61 tggcagcagg aatccaacca gtgccctgag ttctgaggca gagaggagga cagaagaaac121 aagaggctgg agattgtcaa attcagtatc ccagttggct cttgattctt ggtgaaacca181 tccctcagct cctagaggga gattgttaga tcatgaaact aattaccatc cttttcctct241 gctccaggct gctactaagt ttaacccagg aatcacagtc cgaggaaatt gactgcaatg301 acaaggattt atttaaagct gtggatgctg ctctgaagaa atataacagt caaaaccaaa361 gtaacaacca gtttgtattg taccgcataa ctgaagccac taagacggtt ggctctgaca421 cgttttattc cttcaagtac gaaatcaagg agggggattg tcctgttcaa agtggcaaaa481 cctggcagga ctgtgagtac aaggatgctg caaaagcagc cactggagaa tgcacggcaa541 ccgtggggaa gaggagcagt acgaaattct ccgtggctac ccagacctgc cagattactc601 cagccgaggg ccctgtggtg acagcccagt acgactgcct cggctgtgtg catcctatat661 caacgcagag cccagacctg gagcccattc tgagacacgg cattcagtac tttaacaaca721 acactcaaca ttcctccctc ttcatgctta atgaagtaaa acgggcccaa agacaggtgg781 tggctggatt gaactttcga attacctact caattgtgca aacgaattgt tccaaagaga841 attttctgtt cttaactcca gactgcaagt ccctttggaa tggtgatacc ggtgaatgta901 cagataatgc atacatcgat attcagctac gaattgcttc cttctcacag aactgtgaca961 tttatccagg gaaggatttt gtacaaccac ctaccaagat ttgcgtgggc tgccccagag1021 atatacccac caacagccca gagctggagg agacactgac tcacaccatc acaaagctta1081 atgcagagaa taacgcaact ttctatttca agattgacaa tgtgaaaaaa gcaagagtac1141 aggtggtggc tggcaagaaa tattttattg acttcgtggc cagggaaacc acatgttcca1201 aggaaagtaa tgaagagttg accgaaagct gtgagaccaa aaaacttggc caaagcctag1261 attgcaacgc tgaagtttat gtggtaccct gggagaaaaa aatttaccct actgtcaact1321 gtcaaccact gggaatgatc tcactgatga aaaggcctcc aggtttttca cctttccgat1381 catcacgaat aggggaaata aaagaagaaa caactagtca cctaaggtcc tgcgagtaca1441 agggtcgacc cccaaaggca ggggcagagc cagcatctga gagggaggtc tcttgaccaa1501 tgggcagaat cttcactcca ggcacatagc cccaaccacc tctgccagca accttgagag1561 gaaggacaag aagaaagatg ggatagaatt taaatagaga agaatgccat tttatcactc
1621 tgcctctggg tgaaataaag atcagtcttg atgttctaac tctaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>76<211>1388<212>DNA<213>人類(Homo sapitens)<400>761 gggatcctta ttctatatct cttggtattt agtgtaaaaa ttttaaaatc tttacctagc61 aatcttgagg aagaaacttg ataactgata atacatgaga ttgttaccta agtgaaatat121 aatcctatat attcaacaaa ctttagagaa ataagataaa ttttaaagta aatgacttct181 gtagttttat agatcctcca aaccaatcta gtctcagatc tcaccttcat catttctctc241 atttcctttt ggcctaatta atcaaaatcc ttcctagaat gttcatttct ggccagtatg301 tcttcctgaa tatgaataag aaataaaata ccatttgatg tttgaaatta tgggggtaat361 ctcaatgacg gaaatagatg accaggaaaa gggaaacgaa tgcctgattc attatattca421 tgaagatatc aaaggtttat aaagccaata tctgggaaag agaaaaccgt gagacttcca481 gatcttctct ggtgaagtgt gtttcctgca acgatcacga acatgaacat caaaggatcg541 ccatggaaag ggtccctcct gctgctgctg gtgtcaaacc tgctcctgtg ccagagcgtg601 gcccccttgc ccatctgtcc cggcggggct gcccgatgcc aggtgaccct tcgagacctg661 tttgaccgcg ccgtcgtcct gtcccactac atccataacc tctcctcaga aatgttcagc721 gaattcgata aacggtatac ccatggccgg gggttcatta ccaaggccat caacagctgc781 cacacttctt cccttgccac ccccgaagac aaggagcaag cccaacagat gaatcaaaaa841 gactttctga gcctgatagt cagcatattg cgatcctgga atgagcctct gtatcatctg901 gtcacggaag tacgtggtat gcaagaagcc ccggaggcta tcctatccaa agctgtagag961 attgaggagc aaaccaaacg gcttctagag ggcatggagc tgatagtcag ccaggttcat1021 cctgaaacca aagaaaatga gatctaccct gtctggtcgg gacttccatc cctgcagatg1081 gctgatgaag agtctcgcct ttctgcttat tataacctgc tccactgcct acgcagggat1141 tcacataaaa tcgacaatta tctcaagctc ctgaagtgcc gaatcatcca caacaacaac1201 tgctaagccc acatccattt catctatttc tgagaaggtc cttaatgatc cgttccattg1261 caagcttctt ttagttgtat ctcttttgaa tccatgcttg ggtgtaacag gtctcctctt1321 aaaaaataaa aactgactcc ttagagacat caaaatccaa aaaaaaaaaa aaaaaaaaaa1381 aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>77<211>1822<212>DNA<213>人類(Homo sapiens)<400>771 ttgccagaca gcatagaggc tgaggctggg gccaggaccc agacagagac acacggtcac61 tgcagctgaa gccgctgccc ctgctacagg caccaccagg accagctgat cattccagcc121 cacagcaatg gagccacatg actcctccca catggactct gagttccgat acactctctt181 cccgattgtt tacagcatca tctttgtgct cggggtcatt gctaatggct acgtgctgtg241 ggtctttgcc cgcctgtacc cttgcaagaa attcaatgag ataaagatct tcatggtgaa
301 cctcaccatg gcggacatgc tcttcttgat caccctgcca ctttggattg tctactacca361 aaaccagggc aactggatac tccccaaatt cctgtgcaac gtggctggct gccttttctt421 catcaacacc tactgctctg tggccttcct gggcgtcatc acttataacc gcttccaggc481 agtaactcgg cccatcaaga ctgctcaggc caacacccgc aagcgtggca tctctttgtc541 cttggtcatc tgggtggcca ttgtgggagc tgcatcctac ttcctcatcc tggactccac601 caacacagtg cccgacagtg ctggctcagg caacgtcact cgctgctttg agcattacga661 gaagggcagc gtgccagtcc tcatcatcca catcttcatc gtgttcagct tcttcctggt721 cttcctcatc atcctcttct gcaacctggt catcatccgt accttgctca tgcagccggt781 gcagcagcag cgcaacgctg aagtcaagcg ccgggcgctg tggatggtgt gcacggtctt841 ggcggtgttc atcatctgct tcgtgcccca ccacgtggtg cagctgccct ggacccttgc901 tgagctgggc ttccaggaca gcaaattcca ccaggccatt aatgatgcac atcaggtcac961 cctctgcctc cttagcacca actgtgtctt agaccctgtt atctactgtt tcctcaccaa1021 gaagttccgc aagcacctca ccgaaaagtt ctacagcatg cgcagtagcc ggaaatgctc1081 ccgggccacc acggatacgg tcactgaagt ggttgtgcca ttcaaccaga tccctggcaa1141 ttccctcaaa aattagtccc tgcttccagg cctgaagtct tctcctccat gaacatcatg1201 gactgagctg ggggaagaag ggatatctac tgtggtctgg gcaccacctc tgtgggcact1261 ggtgggccat tagatttgga ggctacctca cctgggcagg gatgatggca gagccaggct1321 gttggaaaat ccagaactca aatgagcccc ttcatccgcc tgtgggcgca tactacagta1381 actgtgactg atgactttat cctgagtccc ttaatcttat ggggccggaa ggaatgtcag1441 ggccaggtgc agaccttggg ggaagacttt aaaccaccta gttctccccg atggggcatc1501 ggtctaaagc tttgggggag tgggcgcagt ggctcacacc tgtaatccca gcactttggg1561 aggccgaggt gggcagatca tgggtcaaga gatcgagacc atcctggcca acattgtaaa1621 accccatctc tactaaaaca tacaaaaatt agccgggcat ggtggcacac gcctgtagtc1681 ccagctactc aggaggctga ggcaggagaa tcgcttgaac ctgggaggca gaggttgcag1741 tgaacctaga ttgcaccatt gcactctagc ctggcaacag agcgagattc catctcaaaa1801 aaaaaaaaaa aaaaaaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>78<211>2103<212>DNA<213>人類(Homo sapiens)<400>781 aagctgacac acagaccgac acaggcagcg agagacacga ggagcaaagc aagtgaaggc61 acagacgcac gggacaggag agcctgggca agactggaga gcccagacct gggatggcgg121 attcgtgcag gaacctcacc tacgtgcggg gctcggtggg gccggccacc agcaccctga181 tgttcgtggc cggtgtggtg ggcaacgggc tggccctggg catcctgagc gcacggcgac241 cggcgcgccc ctcggccttc gcggtgctgg tgaccggact ggcggccacc gacctgctgg301 gcaccagctt cctgagcccg gccgtgttcg tggcctatgc gcgcaacagc tccctgctgg361 gcctggcccg aggcggcccc gccctgtgcg atgccttcgc cttcgccatg accttcttcg421 gcctggcgtc catgctcatc ctctttgcca tggccgtgga gcgctgcctg gcgctgagcc481 acccctacct ctacgcgcag ctggacgggc cccgctgcgc ccgcctggcg ctgccagcca541 tctacgcctt ctgcgtcctc ttctgcgcgc tgcccctgct gggcctgggc caacaccagc601 agtactgccc cggcagctgg tgcttcctcc gcatgcgctg ggcccagccg ggcggcgccg661 ccttctcgct ggcctacgcc ggcctggtgg ccctgctggt ggctgccatc ttcctctgca721 acggctcggt caccctcagc ctctgccgca tgtaccgcca gcagaagcgc caccagggct
781 ctctgggtcc acggccgcgc accggagagg acgaggtgga ccacctgatc ctgctggccc841 tcatgacagt ggtcatggcc gtgtgctccc tgcctctcac gatccgctgc ttcacccagg901 ctgtcgcccc tgacagcagc agtgagatgg gggacctcct tgccttccgc ttctacgcct961 tcaaccccat cctggacccc tgggtcttca tccttttccg caaggctgtc ttccagcgac1021 tcaagctctg ggtctgctgc ctgtgcctcg ggcctgccca cggagactcg cagacacccc1081 tttcccagct cgcctcaggg aggagggacc caagggcccc ctctgctcct gtgggaaagg1141 aggggagctg cgtgcctttg tcggcttggg gcgaggggca ggtggagccc ttgcctccca1201 cacagcagtc cagcggcagc gccgtgggaa cgtcgtccaa agcagaagcc agcgtcgcct1261 gctccctctg ctgacatttc aagctgaccc tgtgatctct gccctgtctt cgggcgacag1321 gagccagaaa atcagggaca tggctgatgg ctgcggatgc tggaaccttg gcccccaaac1381 tctggggccg atcagctgct gtttctcctg cggcagggca gtcgctgctg gctctgggaa1441 gagagtgagg gacagaggaa acgtttatcc tggagtgcag aaagaatggt tctctcaaaa1501 taaccagtgg cctggccgac ctgctctggc cctggattcc ccatccatct cattgtctaa1561 atatttagaa ggcggagaag ttcccagagg cttctgtaca gtcaggtctg ctctggtctg1621 ggtgctggct ccaatctgcg tccacttagg aggcccaact gcccacccca agtccccagg1681 ggatggccct ccccctctac caagccactc caagagccag cccctttctg ctccacaaaa1741 accacagtta ttggaaaagc tccctgcctt cccttgccgc tggtccccca ccaggcttgg1801 gagccctggc atcccaaagg ggcaacggga ggaaggggag gctgctgcat tgtgggtgat1861 gacgtaggac atgtgcttgg tacaaaaagg gcctgagaca ttccacctag cttgactggc1921 tgcaagatga gaactggggg ggtgcaggtg gtggggagac agatggagaa gctggcagat1981 gaagggtggg ggctgcggat cccagggact gccccagaac acaaacctaa gtcctgtgcc2041 tgtccccagg gtcctgaata aataaaagcc tccttgcaga gcctgaaaaa aaaaaaaaaa2101 aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>79<211>1630<212>DNA<213>人類(Homo sapiens)<400>791 agggccgggg tggggcgctg gcgtttccgt tgcttggatc agtctaggtg cagctgcgga61 tccttcagcg tctgcatctc ggcgtcgccc cgcgtaccgt cgcccggctc tccgccgctc121 tcccgggggt tcggggcact tgggtcccac agtctggtcc tgcttcacct tcccctgacc181 tgagtagtcg ccatggcaca ggttctcaga ggcactgtga ctgacttccc tggatttgat241 gagcgggctg atgcagaaac tcttcggaag gctatgaaag gcttgggcac agatgaggag301 agcatcctga ctctgttgac atcccgaagt aatgctcagc gccaggaaat ctctgcagct361 tttaagactc tgtttggcag ggatcttctg gatgacctga aatcagaact aactggaaaa421 tttgaaaaat taattgtggc tctgatgaaa ccctctcggc tttatgatgc ttatgaactg481 aaacatgcct tgaagggagc tggaacaaat gaaaaagtac tgacagaaat tattgcttca541 aggacacctg aagaactgag agccatcaaa caagtttatg aagaagaata tggctcaagc601 ctggaagatg acgtggtggg ggacacttca gggtactacc agcggatgtt ggtggttctc661 cttcaggcta acagagaccc tgatgctgga attgatgaag ctcaagttga acaagatgct721 caggctttat ttcaggctgg agaacttaaa tgggggacag atgaagaaaa gtttatcacc781 atctttggaa cacgaagtgt gtctcatttg agaaaggtgt ttgacaagta catgactata841 tcaggatttc aaattgagga aaccattgac cgcgagactt ctggcaattt agagcaacta901 ctccttgctg ttgtgaaatc tattcgaagt atacctgcct accttgcaga gaccctctat
961 tatgctatga agggagctgg gacagatgat cataccctca tcagagtcat ggtttccagg1021 agtgagattg atctgtttaa catcaggaag gagtttagga agaattttgc cacctctctt1081 tattccatga ttaagggaga tacatctggg gactataaga aagctcttct gctgctctgt1141 ggagaagatg actaacgtgt cacggggaag agctccctgc tgtgtgcctg caccacccca1201 ctgccttcct tcagcacctt tagctgcatt tgtatgccag tgcttaacac attgccttat1261 tcatactagc atgctcatga ccaacacata cacgtcatag aagaaaatag tggtgcttct1321 ttctgatctc tagtggagat ctctttgact gctgtagtac taaagtgtac ttaatgttac1381 taagtttaat gcctggccat tttccattta tatatatttt ttaagaggct agagtgcttt1441 tagccttttt taaaaactcc atttatatta catttgtaac catgatactt taattagaag1501 cttagccttg aaattgtgaa ctcttggaaa tgttattagt gaagttcgca actaaactaa1561 acctgtaaaa ttatgatgat tgtattcaaa agattaatga aaaataaaca tttctgtccc1621 cctgaattat<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>80<211>1981<212>DNA<213>人類(Homo sapiens)<400>801 cacggggcgg gcggacgctg gcgcgggtag gtaagagcag cggcgggcgg tggcgctcac61 tcccggcttc caaccgcgcg gagcctctgc cttggagatt ctcagtgctg cggatcatgt121 ccctaagggg cagcctctcg cgtctcctcc agacgcgagt gcattccatc ctgaagaaat181 ccgtccactc cgtggctgtg ataggagccc cgttctcaca agggcagaaa agaaaaggag241 tggagcatgg tcccgctgcc ataagagaag ctggcttgat gaaaaggctc tccagtttgg301 gctgccacct aaaagacttt ggagatttga gttttactcc agtccccaaa gatgatctct361 acaacaacct gatagtgaat ccacgctcag tgggtcttgc caaccaggaa ctggctgagg421 tggttagcag agctgtgtca gatggctaca gctgtgtcac actgggagga gaccacagcc481 tggcaatcgg taccattagt ggccatgccc gacactgccc agacctttgt gttgtctggg541 ttgatgccca tgctgacatc aacacacccc ttaccacttc atcaggaaat ctccatggac601 agccagtttc atttctcctc agagaactac aggataaggt accacaactc ccaggatttt661 cctggatcaa accttgtatc tcttctgcaa gtattgtgta tattggtctg agagacgtgg721 accctcctga acattttatt ttaaagaact atgatatcca gtatttttcc atgagagata781 ttgatcgact tggtatccag aaggtcatgg aacgaacatt tgatctgctg attggcaaga841 gacaaagacc aatccatttg agttttgata ttgatgcatt tgaccctaca ctggctccag901 ccacaggaac tcctgttgtc gggggactaa cctatcgaga aggcatgtat attgctgagg961 aaatacacaa tacagggttg ctatcagcac tggatcttgt tgaagtcaat cctcagttgg1021 ccacctcaga ggaagaggcg aagactacag ctaacctggc agtagatgtg attgcttcaa1081 gctttggtca gacaagagaa ggagggcata ttgtctatga ccaacttcct actcccagtt1141 caccagatga atcagaaaat caagcacgtg tgagaattta ggagacactg tgcactgaca1201 tgtttcacaa caggcattcc agaattatga ggcattgagg ggatagatga atactaaatg1261 gttgtctggg tcaatactgc cttaatgaga acatttacac attctcacaa ttgtaaagtt1321 tcccctctat tttggtgacc aatactactg taaatgtatt tggttttttg cagttcacag1381 ggtattaata tgctacagta ctatgtaaat ttaaagaagt cataaacagc atttattacc1441 ttggtatatc atactggtct tgttgctgtt gttccttcac atttaagtgg tttttcatct1501 ttcctccctc ctcccacagc ctggctatac agtgcatcct tgaactgtca gcccacagca1561 gcaatatgct tattctatcc acatccctaa catcatgcat tcacaaggtc aaagttctgg
1621 tccacaaacc cttccctata gaagttcaat ggctgcgaaa gaatttgtag taaaccaggc1681 ctcccaggat ggcgagctcc agtaagatga taatggaaag cagcagcttg ttggttgtca1741 ctctacaaag agaagcaaag tggggagtag tcagaagttt ggataacctt ccttctaaac1801 attttggggt tagacctggg accacggctg gatactctga ggctgtatgt ttgatcacac1861 agccacttag caggaagtac tcataaggtt ctttagctgt cacttaggga taacactgtc1921 tacctcacag aaatgttaaa ctgagacaat aaaaaccaaa gcataaaaat ggattctgaa1981 a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>81<211>1177<212>DNA<213>人類(Homo sapiens)<400>811 gccaaggctg gggcagggga gtcagcagag gcctcgctcg ggcgcccagt ggtcctgccg61 cctggtctca cctcgctatg gttcgtctgc ctctgcagtg cgtcctctgg ggctgcttgc121 tgaccgctgt ccatccagaa ccacccactg catgcagaga aaaacagtac ctaataaaca181 gtcagtgctg ttctttgtgc cagccaggac agaaactggt gagtgactgc acagagttca241 ctgaaacgga atgccttcct tgcggtgaaa gcgaattcct agacacctgg aacagagaga301 cacactgcca ccagcacaaa tactgcgacc ccaacctagg gcttcgggtc cagcagaagg361 gcacctcaga aacagacacc atctgcacct gtgaagaagg ctggcactgt acgagtgagg421 cctgtgagag ctgtgtcctg caccgctcat gctcgcccgg ctttggggtc aagcagattg481 ctacaggggt ttctgatacc atctgcgagc cctgcccagt cggcttcttc tccaatgtgt541 catctgcttt cgaaaaatgt cacccttgga caagctgtga gaccaaagac ctggttgtgc601 aacaggcagg cacaaacaag actgatgttg tctgtggtcc ccaggatcgg ctgagagccc661 tggtggtgat ccccatcatc ttcgggatcc tgtttgccat cctcttggtg ctggtcttta721 tcaaaaaggt ggccaagaag ccaaccaata aggcccccca ccccaagcag gaaccccagg781 agatcaattt tcccgacgat cttcctggct ccaacactgc tgctccagtg caggagactt841 tacatggatg ccaaccggtc acccaggagg atggcaaaga gagtcgcatc tcagtgcagg901 agagacagtg aggctgcacc cacccaggag tgtggccacg tgggcaaaca ggcagttggc961 cagagagcct ggtgctgctg ctgctgtggc gtgagggtga ggggctggca ctgactgggc1021 atagctcccc gcttctgcct gcacccctgc agtttgagac aggagacctg gcactggatg1081 cagaaacagt tcaccttgaa gaacctctca cttcaccctg gagcccatcc agtctcccaa1141 cttgtattaa agacagaggc agaaaaaaaa aaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>82<211>2094<212>DNA<213>人類(Homo sapiens)<400>821 gcttgttccc tgtcctctgg ccctttgcaa ataaatgcct taccagacct gccctgccac61 cccactcgca gccacccagc aagagcagca tgtcagcctg ccggagcttt gcagttgcaa121 tctgcatttt agaaataagc atcctcacag cacagtacac gaccagttat gacccagagc
181 taacagaaag cagtggctct gcatcacaca tagactgcag aatgagcccc tggagtgaat241 ggtcacaatg cgatccttgt ctcagacaaa tgtttcgttc aagaagcatt gaggtatttg301 gacaatttaa tgggaaaaga tgcaccgacg ctgtgggaga cagacgacag tgtgtgccca361 cagagccctg tgaggatgct gaggatgact gcggaaatga ctttcaatgc agtacaggca421 gatgcataaa gatgcgactt cggtgtaatg gtgacaatga ctgcggagac ttttcagatg481 aggatgattg tgaaagtgag ccccgtcccc cctgcagaga cagagtggta gaagagtctg541 agctggcacg aacagcaggc tatgggatca acattttagg gatggatccc ctaagcacac601 cttttgacaa tgagttctac aatggactct gtaaccggga tcgggatgga aacactctga661 catactaccg aagaccttgg aacgtggctt ctttgatcta tgaaaccaaa ggcgagaaaa721 atttcagaac cgaacattac gaagaacaaa ttgaagcatt taaaagtatc atccaagaga781 agacatcaaa ttttaatgca gctatatctc taaaatttac acccactgaa acaaataaag841 ctgaacaatg ttgtgaggaa acagcctcct caatttcttt acatggcaag ggtagttttc901 ggttttcata ttccaaaaat gaaacttacc aactattttt gtcatattct tcaaagaagg961 aaaaaatgtt tctgcatgtg aaaggagaaa ttcatctggg aagatttgta atgagaaatc1021 gcgatgttgt gctcacaaca acttttgtgg atgatataaa agctttgcca actacctatg1081 aaaagggaga atattttgcc tttttggaaa cctatggaac tcactacagt agctctgggt1141 ctctaggagg actctatgaa ctaatatatg ttttggataa agcttccatg aagcggaaag1201 gtgttgaact aaaagacata aagagatgcc ttgggtatca tctggatgta tctctggctt1261 tctctgaaat ctctgttgga gctgaattta ataaagatga ttgtgtaaag aggggagagg1321 gtagagctgt aaacatcacc agtgaaaacc tcatagatga tgttgtttca ctcataagag1381 gtggaaccag aaaatatgca tttgaactga aagaaaagct tctccgagga accgtgattg1441 atgtgactga ctttgtcaac tgggcctctt ccataaatga tgctcctgtt ctcattagtc1501 aaaaactgtc tcctatatat aatctggttc cagtgaaaat gaaaaatgca cacctaaaga1561 aacaaaactt ggaaagagcc attgaagact atatcaatga atttagtgta agaaaatgcc1621 acacatgcca aaatggaggt acagtgattc taatggatgg aaagtgtttg tgtgcctgcc1681 cattcaaatt tgagggaatt gcctgtgaaa tcagtaaaca aaaaatttct gaaggattgc1741 cagccctaga gttccccaat gaaaaataga gctgttggct tctctgagct ccagtggaag1801 aagaaaacac tagtaccttc agatcctacc cctgaagata atcttagctg ccaagtaaat1861 agcaacatgc ttcatgaaaa tcctaccaac ctctgaagtc tcttctctct taggtctata1921 attttttttt taatttttct tccttaaact cctgtgatgt ttccattttt tgttccctaa1981 tgagaagtca acagtgaaat acgccagaac tgctttatcc cacggaaaat gccaatctct2041 tctaaaaaaa aacaaaatta aactaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>83<211>1246<212>DNA<213>人類(Homo sapiens)<400>831 gaccagccta cagccgcctg catctgtatc cagcgccagg tcccgccagt cccagctgcg61 cgcgcccccc agtcccgcac ccgttcggcc caggctaagt tagccctcac catgccggtc121 aaaggaggca ccaagtgcat caaatacctg ctgttcggat ttaacttcat cttctggctt181 gccgggattg ctgtccttgc cattggacta tggctccgat tcgactctca gaccaagagc241 atcttcgagc aagaaactaa taataataat tccagcttct acacaggagt ctatattctg301 atcggagccg gcgccctcat gatgctggtg ggcttcctgg gctgctgcgg ggctgtgcag361 gagtcccagt gcatgctggg actgttcttc ggcttcctct tggtgatatt cgccattgaa
421 atagctgcgg ccatctgggg atattcccac aaggatgagg tgattaagga agtccaggag481 ttttacaagg acacctacaa caagctgaaa accaaggatg agccccagcg ggaaacgctg541 aaagccatcc actatgcgtt gaactgctgt ggtttggctg ggggcgtgga acagtttatc601 tcagacatct gccccaagaa ggacgtactc gaaaccttca ccgtgaagtc ctgtcctgat661 gccatcaaag aggtcttcga caataaattc cacatcatcg gcgcagtggg catcggcatt721 gccgtggtca tgatatttgg catgatcttc agtatgatct tgtgctgtgc tatccgcagg781 aaccgcgaga tggtctagag tcagcttaca tccctgagca ggaaagttta cccatgaaga841 ttggtgggat tttttgtttg tttgttttgt tttgtttgtt gtttgttgtt tgtttttttg901 ccactaattt tagtattcat tctgcattgc tagataaaag ctgaagttac tttatgtttg961 tcttttaatg cttcattcaa tattgacatt tgtagttgag cggggggttt ggtttgcttt1021 ggtttatatt ttttcagttg tttgtttttg cttgttatat taagcagaaa tcctgcaatg1081 aaaggtacta tatttgctag actctagaca agatattgta cataaaagaa tttttttgtc1141 tttaaataga tacaaatgtc tatcaacttt aatcaagttg taacttatat tgaagacaat1201 ttgatacata ataaaaaatt atgacaatgt caaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>84<211>1959<212>DNA<213>人類(Homo sapiens)<400>841 tctcacggag acggaccaca gcaagcagag gctggggggg ggaaagacga ggaaagagga61 ggaaaacaaa agctgctact tatggaagat acaaaggagt ctaacgtgaa gacattttgc121 tccaagaata tcctagccat ccttggcttc tcctctatca tagctgtgat agctttgctt181 gctgtggggt tgacccagaa caaagcattg ccagaaaacg ttaagtatgg gattgtgctg241 gatgcgggtt cttctcacac aagtttatac atctataagt ggccagcaga aaaggagaat301 gacacaggcg tggtgcatca agtagaagaa tgcagggtta aaggtcctgg aatctcaaaa361 tttgttcaga aagtaaatga aataggcatt tacctgactg attgcatgga aagagctagg421 gaagtgattc caaggtccca gcaccaagag acacccgttt acctgggagc cacggcaggc481 atgcggttgc tcaggatgga aagtgaagag ttggcagaca gggttctgga tgtggtggag541 aggagcctca gcaactaccc ctttgacttc cagggtgcca ggatcattac tggccaagag601 gaaggtgcct atggctggat tactatcaac tatctgctgg gcaaattcag tcagaaaaca661 aggtggttca gcatagtccc atatgaaacc aataatcagg aaacctttgg agctttggac721 cttgggggag cctctacaca agtcactttt gtaccccaaa accagactat cgagtcccca781 gataatgctc tgcaatttcg cctctatggc aaggactaca atgtctacac acatagcttc841 ttgtgctatg ggaaggatca ggcactctgg cagaaactgg ccaaggacat tcaggttgca901 agtaatgaaa ttctcaggga cccatgcttt catcctggat ataagaaggt agtgaacgta961 agtgaccttt acaagacccc ctgcaccaag agatttgaga tgactcttcc attccagcag1021 tttgaaatcc agggtattgg aaactatcaa caatgccatc aaagcatcct ggagctcttc1081 aacaccagtt actgccctta ctcccagtgt gccttcaatg ggattttctt gccaccactc1141 cagggggatt ttggggcatt ttcagctttt tactttgtga tgaagttttt aaacttgaca1201 tcagagaaag tctctcagga aaaggtgact gagatgatga aaaagttctg tgctcagcct1261 tgggaggaga taaaaacatc ttacgctgga gtaaaggaga agtacctgag tgaatactgc1321 ttttctggta cctacattct ctccctcctt ctgcaaggct atcatttcac agctgattcc1381 tgggagcaca tccatttcat tggcaagatc cagggcagcg acgccggctg gactttgggc1441 tacatgctga acctgaccaa catgatccca gctgagcaac cattgtccac acctctctcc
1501 cactccacct atgtcttcct catggttcta ttctccctgg tccttttcac agtggccatc1561 ataggcttgc ttatctttca caagccttca tatttctgga aagatatggt atagcaaaag1621 cagctgaaat atgctggctg gagtgaggaa aaaaatcgtc cagggagcat tttcctccat1681 cgcagtgttc aaggccatcc ttccctgtct gccagggcca gtcttgacga gtgtgaagct1741 tccttggctt ttactgaagc ctttcttttg gaggtattca atatcctttg cctcaaggac1801 ttcggcagat actgtctctt tcatgagttt ttcccagcta cacctttctc ctttgtactt1861 tgtgcttgta taggttttaa agacctgaca cctttcataa tctttgcttt ataaaagaac1921 aatattgact ttgtctagaa aaaaaaaaaa aaaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>85<211>2153<212>DNA<213>人類(Homo sapiens)<400>851 aagactgcga gctccccgca ccccctcgca ctccctctgg ccggcccagg gcgccttcag61 cccaacctcc ccagccccac gggcgccacg gaacccgctc gatctcgccg ccaactggta121 gacatggaga cccctgcctg gccccgggtc ccgcgccccg agaccgccgt cgctcggacg181 ctcctgctcg gctgggtctt cgcccaggtg gccggcgctt caggcactac aaatactgtg241 gcagcatata atttaacttg gaaatcaact aatttcaaga caattttgga gtgggaaccc301 aaacccgtca atcaagtcta cactgttcaa ataagcacta agtcaggaga ttggaaaagc361 aaatgctttt acacaacaga cacagagtgt gacctcaccg acgagattgt gaaggatgtg421 aagcagacgt acttggcacg ggtcttctcc tacccggcag ggaatgtgga gagcaccggt481 tctgctgggg agcctctgta tgagaactcc ccagagttca caccttacct ggagacaaac541 ctcggacagc caacaattca gagttttgaa caggtgggaa caaaagtgaa tgtgaccgta601 gaagatgaac ggactttagt cagaaggaac aacactttcc taagcctccg ggatgttttt661 ggcaaggact taatttatac actttattat tggaaatctt caagttcagg aaagaaaaca721 gccaaaacaa acactaatga gtttttgatt gatgtggata aaggagaaaa ctactgtttc781 agtgttcaag cagtgattcc ctcccgaaca gttaaccgga agagtacaga cagcccggta841 gagtgtatgg gccaggagaa aggggaattc agagaaatat tctacatcat tggagctgtg901 gtatttgtgg tcatcatcct tgtcatcatc ctggctatat ctctacacaa gtgtagaaag961 gcaggagtgg ggcagagctg gaaggagaac tccccactga atgtttcata aaggaagcac1021 tgttggagct actgcaaatg ctatattgca ctgtgaccga gaacttttaa gaggatagaa1081 tacatggaaa cgcaaatgag tatttcggag catgaagacc ctggagttca aaaaactctt1141 gatatgacct gttattacca ttagcattct ggttttgaca tcagcattag tcactttgaa1201 atgtaacgaa tggtactaca accaattcca agttttaatt tttaacacca tggcaccttt1261 tgcacataac atgctttaga ttatatattc cgcacttaag gattaaccag gtcgtccaag1321 caaaaacaaa tgggaaaatg tcttaaaaaa tcctgggtgg acttttgaaa agcttttttt1381 tttttttttt tttgagacgg agtcttgctc tgttgcccag gctggagtgc agtagcacga1441 tctcggctca cttgcaccct ccgtctctcg ggttcaagca attgtctgcc tcagcctccc1501 gagtagctgg gattacaggt gcgcactacc acgccaagct aatttttgta ttttttagta1561 gagatggggt ttcaccatct tggccaggct ggtcttgaat tcctgacctc agtgatccac1621 ccaccttggc ctcccaaaga tgctagtatt atgggcgtga accaccatgc ccagccgaaa1681 agcttttgag gggctgactt caatccatgt aggaaagtaa aatggaagga aattgggtgc1741 atttctagga cttttctaac atatgtctat aatatagtgt ttaggttctt ttttttttca1801 ggaatacatt tggaaattca aaacaattgg gcaaactttg tattaatgtg ttaagtgcag
1861 gagacattgg tattctgggc agcttcctaa tatgctttac aatctgcact ttaactgact1921 taagtggcat taaacatttg agagctaact atatttttat aagactacta tacaaactac1981 agagtttatg atttaaggta cttaaagctt ctatggttga cattgtatat ataatttttt2041 aaaaaggttt ttctatatgg ggattttcta tttatgtagg taatattgtt ctatttgtat2101 atattgagat aatttattta atatacttta aataaaggtg actgggaatt gtt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>86<211>2208<212>DNA<213>人類(Homo sapiens)<400>861 cttattgata acctcagacg ttcccaccac tgaagatgag gttgaaaaac ctgactttta61 tcatcatatt gataatctca ggagagctct atgcagaaga gaaaccctgt ggttttcctc121 atgtggaaaa tggaagaatt gcccaatatt actatacttt taaaagcttt tactttccaa181 tgagcataga caaaaaattg tcatttttct gcttggctgg ttataccact gaaagtggaa241 gacaagaaga gcaaaccacg tgtacaacag aaggctggtc tccagagcca aggtgcttca301 aaaaatgcac taagcctgac ctgagtaatg gttacatctc tgatgtaaag ttattgtata361 aaattcaaga gaacatgcat tatggttgcg cttcagggta caaaaccact ggagggaagg421 atgaagaagt ggttcaatgt ctctctgatg gatggtcttc tcaaccaacc tgtaggaaag481 aacatgaaac gtgtttggct cctgaattat ataatggaaa ttattccaca acacagaaaa541 cattcaaagt gaaggacaaa gtacaatacg aatgtgctac tggctactac acagctggag601 gaaagaagac agaggaggta gaatgtctca catacggatg gtctctcaca ccaaaatgta661 ccaaattaaa gtgctcttct ttaagattaa ttgaaaatgg ttattttcat cctgtaaagc721 aaacctatga agaaggagat gtcgttcagt ttttctgtca tgaaaattat tatctaagtg781 gatctgattt aattcaatgc tataactttg gttggtaccc agaatctcct gtatgcgaag841 gaagaagaaa cagatgtcct cctccacctc tgcccataaa ctccaaaatt caaacacatt901 caacaactta tcgtcatgga gaaatagttc atatagaatg tgaacttaat tttgagatcc961 atgggtcagc agaaatacgt tgtgaagatg gaaaatggac agaacctcca aaatgcattg1021 aaggacagga gaaggtagcc tgtgaggaac cacccttcat tgaaaatggt gcagcaaatt1081 tacactctaa gatttattac aatggggata aagtgacata tgcatgtaaa agcggctacc1141 ttctccatgg atcgaatgag ataacttgta atcgtggaaa atggacactt cctcctgagt1201 gtgttgaaaa taatgagaat tgtaagcatc ctcctgttgt aatgaatggg gctgttgcag1261 acgggatatt ggcaagctat gcaacaggat cctcagtgga atatagatgc aatgaatatt1321 acttactgag gggatcaaaa atatctcgtt gcgaacaagg aaaatggtca tccccacctg1381 tttgcttgga accatgtact gttaatgtgg attacatgaa cagaaataac atagaaatga1441 agtggaaata tgaagggaaa gtcttacatg gagatttaat agattttgta tgtaaacagg1501 gatatgactt atctccatta accccattgt ctgaattatc tgtgcagtgc aacagaggag1561 aagtgaaata tcctttatgt actagaaaag aatctaaagg aatgtgcaca tctcctcctc1621 ttattaaaca tggagtcatt attagttcaa cagtagacac ctatgaaaat ggctcttcag1681 tagaatacag atgttttgat caccatttcc tagaaggatc tagggaggcc tattgtttag1741 atggaatgtg gactacacca ccattgtgtt tagagccatg cacattatct tttactgaaa1801 tggaaaagaa taatttactt ctgaaatggg attttgacaa cagaccacac attttgcatg1861 gtgaatatat tgagtttatt tgtagaggag atacttatcc agctgaatta tatattactg1921 gatctatact tagaatgcaa tgtgacagag ggcagttaaa atatccaaga tgtattccaa1981 gacaaagcac tctgtcttat caagaacgct taagaacata gaaatgaatg gcagaaagag
2041 gagtcatatt tcaatacatc atgaaattcc ttataaaata taattttgag gaaataagtt2101 aaaaacttcg gagtttttcc ttgcttaaat atttgaatct aaattatttg tgctgaacat2161 ttcattattt ataaatgaaa accaataaat gtctaatttt tagtttgt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>87<211>5361<212>DNA<213>人類(Homo sapiens)<400>871 ctgcaaaccc agcgcaacta cggtcccccg gtcagaccca ggatggggcc agaacggaca61 ggggccgcgc cgctgccgct gctgctggtg ttagcgctca gtcaaggcat tttaaattgt121 tgtttggcct acaatgttgg tctcccagaa gcaaaaatat tttccggtcc ttcaagtgaa181 cagtttgggt atgcagtgca gcagtttata aatccaaaag gcaactggtt actggttggt241 tcaccctgga gtggctttcc tgagaaccga atgggagatg tgtataaatg tcctgttgac301 ctatccactg ccacatgtga aaaactaaat ttgcaaactt caacaagcat tccaaatgtt361 actgagatga aaaccaacat gagcctcggc ttgatcctca ccaggaacat gggaactgga421 ggttttctca catgtggtcc tctgtgggca cagcaatgtg ggaatcagta ttacacaacg481 ggtgtgtgtt ctgacatcag tcctgatttt cagctctcag ccagcttctc acctgcaact541 cagccctgcc cttccctcat agatgttgtg gttgtgtgtg atgaatcaaa tagtatttat601 ccttgggatg cagtaaagaa ttttttggaa aaatttgtac aaggccttga tataggcccc661 acaaagacac aggtggggtt aattcagtat gccaataatc caagagttgt gtttaacttg721 aacacatata aaaccaaaga agaaatgatt gtagcaacat cccagacatc ccaatatggt781 ggggacctca caaacacatt cggagcaatt caatatgcaa gaaaatatgc ctattcagca841 gcttctggtg ggcgacgaag tgctacgaaa gtaatggtag ttgtaactga cggtgaatca901 catgatggtt caatgttgaa agctgtgatt gatcaatgca accatgacaa tatactgagg961 tttggcatag cagttcttgg gtacttaaac agaaacgccc ttgatactaa aaatttaata1021 aaagaaataa aagcgatcgc tagtattcca acagaaagat actttttcaa tgtgtctgat1081 gaagcagctc tactagaaaa ggctgggaca ttaggagaac aaattttcag cattgaaggt1141 actgttcaag gaggagacaa ctttcagatg gaaatgtcac aagtgggatt cagtgcagat1201 tactcttctc aaaatgatat tctgatgctg ggtgcagtgg gagcttttgg ctggagtggg1261 accattgtcc agaagacatc tcatggccat ttgatctttc ctaaacaagc ctttgaccaa1321 attctgcagg acagaaatca cagttcatat ttaggttact ctgtggctgc aatttctact1381 ggagaaagca ctcactttgt tgctggtgct cctcgggcaa attataccgg ccagatagtg1441 ctatatagtg tgaatgagaa tggcaatatc acggttattc aggctcaccg aggtgaccag1501 attggctcct attttggtag tgtgctgtgt tcagttgatg tggataaaga caccattaca1561 gacgtgctct tggtaggtgc accaatgtac atgagtgacc taaagaaaga ggaaggaaga1621 gtctacctgt ttactatcaa aaagggcatt ttgggtcagc accaatttct tgaaggcccc1681 gagggcattg aaaacactcg atttggttca gcaattgcag ctctttcaga catcaacatg1741 gatggcttta atgatgtgat tgttggttca ccactagaaa atcagaattc tggagctgta1801 tacatttaca atggtcatca gggcactatc cgcacaaagt attcccagaa aatcttggga1861 tccgatggag cctttaggag ccatctccag tactttggga ggtccttgga tggctatgga1921 gatttaaatg gggattccat caccgatgtg tctattggtg cctttggaca agtggttcaa1981 ctctggtcac aaagtattgc tgatgtagct atagaagctt cattcacacc agaaaaaatc2041 actttggtca acaagaatgc tcagataatt ctcaaactct gcttcagtgc aaagttcaga2101 cctactaagc aaaacaatca agtggccatt gtatataaca tcacacttga tgcagatgga
2161 ttttcatcca gagtaacctc cagggggtta tttaaagaaa acaatgaaag gtgcctgcag2221 aagaatatgg tagtaaatca agcacagagt tgccccgagc acatcattta tatacaggag2281 ccctctgatg ttgtcaactc tttggatttg cgtgtggaca tcagtctgga aaaccctggc2341 actagccctg cccttgaagc ctattctgag actgccaagg tcttcagtat tcctttccac2401 aaagactgtg gtgaggatgg actttgcatt tctgatctag tcctagatgt ccgacaaata2461 ccagctgctc aagaacaacc ctttattgtc agcaaccaaa acaaaaggtt aacattttca2521 gtaacactga aaaataaaag ggaaagtgca tacaacactg gaattgttgt tgatttttca2581 gaaaacttgt tttttgcatc attctcccta ccggttgatg ggacagaagt aacatgccag2641 gtggctgcat ctcagaagtc tgttgcctgc gatgtaggct accctgcttt aaagagagaa2701 caacaggtga cttttactat taactttgac ttcaatcttc aaaaccttca gaatcaggcg2761 tctctcagtt tccaagcctt aagtgaaagc caagaagaaa acaaggctga taatttggtc2821 aacctcaaaa ttcctctcct gtatgatgct gaaattcact taacaagatc taccaacata2881 aatttttatg aaatctcttc ggatgggaat gttccttcaa tcgtgcacag ttttgaagat2941 gttggtccaa aattcatctt ctccctgaag gtaacaacag gaagtgttcc agtaagcatg3001 gcaactgtaa tcatccacat ccctcagtat accaaagaaa agaacccact gatgtaccta3061 actggggtgc aaacagacaa ggctggtgac atcagttgta atgcagatat caatccactg3121 aaaataggac aaacatcttc ttctgtatct ttcaaaagtg aaaatttcag gcacaccaaa3181 gaattgaact gcagaactgc ttcctgtagt aatgttacct gctggttgaa agacgttcac3241 atgaaaggag aatactttgt taatgtgact accagaattt ggaacgggac tttcgcatca3301 tcaacgttcc agacagtaca gctaacggca gctgcagaaa tcaacaccta taaccctgag3361 atatatgtga ttgaagataa cactgttacg attcccctga tgataatgaa acctgatgag3421 aaagccgaag taccaacagg agttataata ggaagtataa ttgctggaat ccttttgctg3481 ttagctctgg ttgcaatttt atggaagctc ggcttcttca aaagaaaata tgaaaagatg3541 accaaaaatc cagatgagat tgatgagacc acagagctca gtagctgaac cagcagacct3601 acctgcagtg ggaaccggca gcatcccagc cagggtttgc tgtttgcgtg catggatttc3661 tttttaaatc ccatattttt tttatcatgt cgtaggtaaa ctaacctggt attttaagag3721 aaaactgcag gtcagtttgg atgaagaaat tgtggggggt gggggaggtg cggggggcag3781 gtagggaaat aatagggaaa atacctattt tatatgatgg gggaaaaaaa gtaatcttta3841 aactggctgg cccagagttt acattctaat ttgcattgtg tcagaaacat gaaatgcttc3901 caagcatgac aacttttaaa gaaaaatatg atactctcag attttaaggg ggaaaactgt3961 tctctttaaa atatttgtct ttaaacagca actacagaag tggaagtgct tgatatgtaa4021 gtacttccac ttgtgtatat tttaatgaat attgatgtta acaagagggg aaaacaaaac4081 acaggttttt tcaatttatg ctgctcatcc aaagttgcca cagatgatac ttccaagtga4141 taattttatt tataaactag gtaaaatttg ttgttggttc cttttatacc acggctgccc4201 cttccacacc ccatcttgct ctaatgatca aaacatgctt gaataactga gcttagagta4261 tacctcctat atgtccattt aagttaggag agggggcgat atagagacta aggcacaaaa4321 ttttgtttaa aactcagaat ataacattta tgtaaaatcc catctgctag aagcccatcc4381 tgtgccagag gaaggaaaag gaggaaattt cctttctctt ttaggaggca caacagttct4441 cttctaggat ttgtttggct gactggcagt aacctagtga atttttgaaa gatgagtaat4501 ttctttggca accttcctcc tcccttactg aaccactctc ccacctcctg gtggtaccat4561 tattatagaa gccctctaca gcctgacttt ctctccagcg gtccaaagtt atcccctcct4621 ttacccctca tccaaagttc ccactccttc aggacagctg ctgtgcatta gatattaggg4681 gggaaagtca tctgtttaat ttacacactt gcatgaatta ctgtatataa actccttaac4741 ttcagggagc tattttcatt tagtgctaaa caagtaagaa aaataagcta gagtgaattt4801 ctaaatgttg gaatgttatg ggatgtaaac aatgtaaagt aaaacactct caggatttca4861 ccagaagtta cagatgaggc actggaaacc accaccaaat tagcaggtgc accttctgtg4921 gctgtcttgt ttctgaagta ctttttcttc cacaagagtg aatttgacct aggcaagttt4981 gttcaaaagg tagatcctga gatgatttgg tcagattggg ataaggccca gcaatctgca
5041 ttttaacaag caccccagtc actaggatgc agatggacca cactttgaga aacaccaccc5101 atttctactt tttgcacctt attttctctg ttcctgagcc cccacattct ctaggagaaa5161 cttagattaa aattcacaga cactacatat ctaaagcttt gacaagtcct tgacctctat5221 aaacttcaga gtcctcatta taaaatggga agactgagct ggagttcagc agtgatgctt5281 tttagtttta aaagtctatg atctgatctg gacttcctat aatacaaata cacaatcctc5341 caagaatttg acttggaaaa g<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>88<211>1548<212>DNA<213>人類(Homo sapiens)<400>881 cagggccgag ccagcccctt caccaccagc cggccgcgcc ccgggaaggg aagtttgtgg61 cggaggaggt tcgtacggga ggagggggag gcgcccacgc atctggggct gactcgctct121 ttcgcaaaac gtctgggagg agtccctggg gccacaaaac tgcctcct tcctgaggccag181 aaggagagaa gacgtgcagg gaccccgcgc acaggagctg ccctcgcgac atgggtcacc241 cgccgctgct gccgctgctg ctgctgctcc acacctgcgt cccagcctct tggggcctgc301 ggtgcatgca gtgtaagacc aacggggatt gccgtgtgga agagtgcgcc ctgggacagg361 acctctgcag gaccacgatc gtgcgcttgt gggaagaagg agaagagctg gagctggtgg421 agaaaagctg tacccactca gagaagacca acaggaccct gagctatcgg actggcttga481 agatcaccag ccttaccgag gttgtgtgtg ggttagactt gtgcaaccag ggcaactctg541 gccgggctgt cacctattcc cgaagccgtt acctcgaatg catttcctgt ggctcatcag601 acatgagctg tgagaggggc cggcaccaga gcctgcagtg ccgcagccct gaagaacagt661 gcctggatgt ggtgacccac tggatccagg aaggtgaaga agggcgtcca aaggatgacc721 gccacctccg tggctgtggc taccttcccg gctgcccggg ctccaatggt ttccacaaca781 acgacacctt ccacttcctg aaatgctgca acaccaccaa atgcaacgag ggcccaatcc841 tggagcttga aaatctgccg cagaatggcc gccagtgtta cagctgcaag gggaacagca901 cccatggatg ctcctctgaa gagactttcc tcattgactg ccgaggcccc atgaatcaat961 gtctggtagc caccggcact cacgaaccga aaaaccaaag ctatatggta agaggctgtg1021 caaccgcctc aatgtgccaa catgcccacc tgggtgacgc cttcagcatg aaccacattg1081 atgtctcctg ctgtactaaa agtggctgta accacccaga cctggatgtc cagtaccgca1141 gtggggctgc tcctcagcct ggccctgccc atctcagcct caccatcacc ctgctaatga1201 ctgccagact gtggggaggc actctcctct ggacctaaac ctgaaatccc cctctctgcc1261 ctggctggat ccgggggacc cctttgccct tccctcggct cccagcccta cagacttgct1321 gtgtgacctc aggccagtgt gccgacctct ctgggcctca gttttcccag ctatgaaaac1381 agctatctca caaagttgtg tgaagcagaa gagaaaagct ggaggaaggc cgtgggccaa1441 tgggagagct cttgttatta ttaatattgt tgccgctgtt gtgttgttgt tattaattaa1501 tattcatatt atttatttta tacttacata aagattttgt accagtgg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>89<211>643<212>DNA
<213>人類(Homo sapiens)<400>891 ggtagcgacg gtagctctag ccgggcctga gctgtgctag cacctccccc aggagaccgt61 tgcagtcggc cagccccctt ctccacggta accatgtgcg accgaaaggc cgtgatcaaa121 aatgcggaca tgtcggaaga gatgcaacag gactcggtgg agtgcgctac tcaggcgctg181 gagaaataca acatagagaa ggacattgcg gctcatatca agaaggaatt tgacaagaag241 tacaatccca cctggcattg catcgtgggg aggaacttcg gtagttatgt gacacatgaa301 accaaacact tcatctactt ctacctgggc caagtggcca ttcttctgtt caaatctggt361 taaaagcatg gactgtgcca cacacccagt gatccatcca gaaacaagga ctgcagccta421 aattccaaat accagagact gaaattttca gccttgctaa gggaacatct cgatgtttga481 acctttgttg tgttttgtac agggcattct ctgtactagt ttgtcgtggt tataaaacaa541 ttagcagaat agcctacatt tgtatttatt ttctattcca tacttctgcc cacgttgttt601 tctctcaaaa tccattcctt taaaaaataa atctgatgca ccg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>90<211>1485<212>DNA<213>人類(Homo sapiens)<400>901 ggtgggaatg gcaggctgcg tcccactgct ccagggcctg gtcctggtcc tcgccctcca61 tcgtgtggag ccctcagtat ttctcccggc ctccaaagca aacgacgttc tggtgaggtg121 gaagcgtgcg ggctcctatc ttctggaaga actcttcgag ggaaacttgg aaaaagaatg181 ttatgaagaa atctgtgtct atgaagaagc aagagaagtg tttgaaaatg aagtagtcac241 tgatgaattc tggagacgat ataagggcgg ctccccgtgc atctcccagc cctgcctcca301 caacggctct tgccaggaca gcatctgggg ctacacctgc acctgctccc ccggctatga361 gggcagcaac tgcgagctgg ctaaaaatga atgtcaccca gagcggactg atgggtgtca421 acacttctgc ctcccaggac aggaatccta cacgtgcagc tgtgctcagg gctacaggct481 tggtgaggac cacaaacagt gtgtgcccca cgaccagtgt gcctgcgggg tgctgacctc541 tgagaagcgt gcaccggatc tacaggacct cccgtggcag gtaaagttaa caaattccga601 aggaaaagac ttctgtggtg gtgttataat acgggaaaat tttgtactga caacagcaaa661 atgttcactg ttacacagga atattactgt aaaaacatat tttaacagaa cgagccaaga721 cccgctgatg atcaagataa cgcacgtcca tgtgcacatg cggtatgacg cggacgcggg781 ggagaatgac ctgtcactgc tggagctgga gtggcccatc cagtgcccag gtgcggggct841 ccccgtgtgc acccctgaga aagacttcgc tgagcacctc ctcatcccac gcaccagggg901 cctcctcagc ggctgggcac gcaatggcac tgacctgggc aactcgctga ccacgcggcc961 tgtcacactt gtggaggggg aggagtgcgg gcaggtcctg aatgtgactg tcaccaccag1021 gacctactgt gagagaagca gcgtggcggc catgcactgg atggatggaa gtgtggtcac1081 cagagaacac agaggctcct ggtttctcac gggggtcctg ggctcgcagc cagtaggagg1141 gcaggctcac atggtccttg tcaccaaggt ctccaggtac tcactctggt ttaaacagat1201 catgaactaa ctgaaactca gctagccaga atgaacaaca caaccggaag cgggattcca1261 agctggcact gccactgtgg agggcgctga aacttcatca cacactgaga ggccgtcaca1321 gccccagacc acccgcttgg cccacgcagc agcagagccg ccgtttgctg ggttgtttac1381 cgagcactgt gacctttctt tccctggaac tctttatctc aatagagacc ttaaaagaaa1441 acatgagata cgttaaataa taaaataaga taatctgtca gtcat
<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>91<211>3427<212>DNA<213>人類(Homo sapiens)<400>911 gtggattaca tcctttccct gcggaggacc agggcaagtt tcctgcctgc acggcacagg61 agagcaaact tctacagaca gaccaaggct tccatttgct gctgacacat ggaactgagg121 tgaaattgtg ctccatgatt ttacagattt cataacgttt aagagacggg actcaggtca181 tcaaaatgaa agccctcatc tttgcagctg ctggcctcct gcttctgttg cccacttttt241 gtcagagtgg catggaaaat gatacaaaca acttggcaaa gccaacctta cccattaaga301 cctttcgtgg agctccccca aattcttttg aagagttccc cttttctgcc ttggaaggct361 ggacaggagc cacgattact gtaaaaatta agtgccctga agaaagtgct tcacatctcc421 atgtgaaaaa tgctaccatg gggtacctga ccagctcctt aagtactaaa ctgatacctg481 ccatctacct cctggtgttt gtagttggtg tcccggccaa tgctgtgacc ctgtggatgc541 ttttcttcag gaccagatcc atctgtacca ctgtattcta caccaacctg gccattgcag601 attttctttt ttgtgttaca ttgcccttta agatagctta tcatctcaat gggaacaact661 gggtatttgg agaggtcctg tgccgggcca ccacagtcat cttctatggc aacatgtact721 gctccattct gctccttgcc tgcatcagca tcaaccgcta cctggccatc gtccatcctt781 tcacctaccg gggcctgccc aagcacacct atgccttggt aacatgtgga ctggtgtggg841 caacagtttt cttatatatg ctgccatttt tcatactgaa gcaggaatat tatcttgttc901 agccagacat caccacctgc catgatgttc acaacacttg cgagtcctca tctcccttcc961 aactctatta cttcatctcc ttggcattct ttggattctt aattccattt gtgcttatca1021 tctactgcta tgcagccatc atccggacac ttaatgcata cgatcataga tggttgtggt1081 atgttaaggc gagtctcctc atccttgtga tttttaccat ttgctttgct ccaagcaata1141 ttattcttat tattcaccat gctaactact actacaacaa cactgatggc ttatatttta1201 tatatctcat agctttgtgc ctgggtagtc ttaatagttg cttagatcca ttcctttatt1261 ttctcatgtc aaaaaccaga aatcactcca ctgcttacct tacaaaatag tgaaatgatc1321 ttagagaaca aggacagcca tcacagagaa cgtctgtttt caagaacaac ataagcatag1381 tgcaaggagc tccatttccg agctcctaag aaatatgctt caaaggtcaa acattacaaa1441 agcattagta gtttgtttgt ttgtttttga gactgagtct cactttatca cccagactgg1501 cgtgcagtgg cactatcttg gctcattgca acctctgcct cccaggtcag cctcccaagt1561 agctgggatt acaccaccat gcccagctac taaaaatact tgtattttta gtagagacgg1621 ggtttcacca tgttgaccag gctggtcttg aactcctgac ctcaagtgat cttccggcct1681 cagcctccca aagtgctgga ttacaggcgt gagccactga gccagccagc attagtaatt1741 tttaaaaaca ctttatcagt attttaaaaa tgttaatgca ggagaaaaga tatcacaact1801 ctatggaaaa tgacatttcc atttgcctta ttgctacttc aagctcttta aatcaccatc1861 ttccctattt ctgtgagtgg tattgccatc cttgacattt gacatcattt tttattcttt1921 ggtctctttt gactctcatg ctggtggctg cctcatcaac tgattctatc tttgtagggt1981 ccctcaccag ggtcttttat ctagtttcac ctttgccttc ttttttcctt tttttaatag2041 agacagtgtc tcgcttcgtc acctggctga agtgcagtag cctgatcata gctcacttca2101 gcctccaact cctgggctca agcaatcctg ctgtctcagc ctcccaagta actaagacta2161 caggcatgca ccaccatacc caactaattt tattttttat tttttgcaga gatggagtct2221 cactgttgcc caggctggtc ttgaactcct ggtctcgagt gatcttccta tctcagcctc2281 ccaaagtgct gggactacag gcatgagcca ctacgtccag gccacctcta ccttctaacc2341 attctctcca ctgccagcct accctccacc acttcacaag tcctgccaga ttaatcttcc
2401 ttagatatca gttaggatac atcactaaaa catttccact aactccactg tttctataat2461 aaatcataaa tctttagcct ggcattcaag gctaacttgc taatcacact tcccattaaa2521 ccttgcttat gatataggca ccaaccaaac ctcttgctct gctatatctc cactctgcct2581 cagactgaaa agctagtcct aacgtctttg ccttaattct gttcattttt tcaagtcctt2641 gaaggaccat tcttccctga ttctcaggct agaagtgtca cttttcttat ctgtacttcc2701 aaagcacttt cgtatatttt tattatggca tttatatata gttcatttat atttaaattt2761 taattccatg aacaatcaag taccaagtat aatggagaag gtgctcatcc tctgccttcc2821 ttgagcttct gggtgatgcc aggcccaagt ctttgtggca cccagctcca tgctttgaat2881 actatgtggc tgaatgaatt tttaaaatct caaagcagtt aaacagcagg aaagcccatt2941 aacttcgtac tgaaaaagca acatactgtg atgatacggg atgacatcat ttcaggttgg3001 gcatacaaaa aagtaaggaa gctaaactaa gactatactc accaggccat ttagaagttt3061 taaataatgc ctccactatt ttttttctta gacatagctt ttaatgggga aatggaattt3121 tgttattaat acccattata ttcctgtaag taaatgacta tttttccctt aactcagtga3181 ttagacagga aggaagacat tagtgattag acaggaggga agatattagt gattagacag3241 cagggaagat attagtggta aagagtgaat gatagtagtg aatataaatg gggctgagga3301 aactttaagc ataaaagatt cctgagatga ctttacaagt ctgtacgaat ctgccttgac3361 tgtatatttc atactgccca acaaaacaat aaaaaacaat tttaaatgca aaaaaaaaaa3421 aaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>92<211>1904<212>DNA<213>人類(Homo sapiens)<400>921 gcccgcgcgg gatccgggtg gctgcaggct gctggcttct gcggctgcgg ggtcggggtc61 gcggccaggg ccaagccgca gcgagttcac aggcggaacc cctgcaggcg gcgcccccta121 cgcgaggtca cccctgggaa ggagcgcagc ccacccggcc cctccgcatc cgagcaggac181 gcccgtctcc tctccctgag gatttcaggt ctccctgtcc caggaggctt gtgccaagat241 ggcatcagct ggagacaccc aggcaggccc acgggatgca gcagatcaga acttcgacta301 tatgttcaaa ctgctactga taggcaacag cagtgtgggc aagacttcct tcctgttccg361 atacgcggac gactccttca ctcccgcctt cgtcagtact gtgggcatcg atttcaaggt421 caagaccgtc taccgccatg acaagaggat caagctgcag atctgggaca cagcgggcca481 ggagcgctac cgcaccatca ccacggccta ctaccgggga gccatgggct tcctgctcat541 gtatgacatc gccaatcagg aatcctttgc cgctgtgcag gactgggcca cgcaaatcaa601 gacctactcc tgggacaacg cccaggtcat cctggtgggg aacaagtgtg acctggagga661 cgaacgtgtt gtgcctgctg aggatggccg gaggctcgcc gacgaccttg gtttcgagtt721 ctttgaagcc agtgccaagg agaacatcaa tgtgaagcag gtcttcgagc gcctggtgga781 tgtcatctgc gagaagatga acgagtccct ggaacccagc tccagctcag gcagcaacgg841 gaaaggcccg gccgtggggg atgctccagc cccccagccc agcagctgca gctgctagag901 atggccccca accccccacc cacccctctc ctgcctcggc agggactgtg atcgaggcgt961 gagccacagt ggttatctcc aagctcaggg caatcccttc cctcctgtca actgctcccc1021 gactcctgca tggctcattc cttcacaatg tcgccgtggc tgccaggttc ctcaggcagc1081 cccggtggga ggctgcggac catggggact cagctctgca tggcaggcag aggcccaggg1141 acactgacgt gcatgagctt gctgctttcc agggtgtgtt gagggtggcc atgggtgaca1201 cgtcccactc tttctgatgg aggggcatcc gtggtgcctt ctagcttaga accattttcc
1261 aggtctcttc tgggttgggc aggactgata ttcccaagct ggtggaagat ggttcatctt1321 cctcgcacag tgtgggttct tggagttcat ccagggaagg cggcgcctct ttctcaggtc1381 ctgcaggctg gtctctgagc ctgcccccac gaactttctg gattccaagg tgggatggtg1441 atccctttga cccctgcaga ccctctactt gcgaaaagca gcattgaagc agccttttcc1501 cattgtagaa gggacaggga gtcagatccc ctcaaccccc cggcttcagg gaccccagaa1561 gtgccttcca agcttccccc aagatccaca tcacccacga ccctgccact gtttttgctg1621 tgttcaccac atctctgatc ctgaagtgaa ttctggaact atggaccaca ttagactggg1681 cagagattcg cccaacccct agcactccgg ctctgggctt tcggccagaa gttaattaac1741 ctcagagcca ggagcctggg gctggggcct ccctcccagg ccctgtttag ctgtttagct1801 ggttgtgttt taagcaagtt cttgcccaat catgcatcct gctagaaaag gaaatgaagc1861 aacgttccca gccaccgcaa aaaaaaaaaa aaaaaaaaaa aaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>93<211>1285<212>DNA<213>人類(Homo sapiens)<400>931 aattacaaat tcccaatgca gttacaggat cctgggaagc agagtgtctg gatggaacct61 gagctgggtc tctgactcac ttctgacttt agttttttca agggggaaca tggcaaaggt121 gttcagtttc atccttgtta ccaccgctct gacaatgggc agggaaattt cggcgctcga181 ggactgtgcc caggagcaga tgcggctcag agcccaggtg cgcctgcttg agacccgggt241 caaacagcaa caggtcaaga tcaagcagct tttgcaggag aatgaagtcc agttccttga301 taaaggagat gagaatactg tcattgatct tggaagcaag aggcagtatg cagattgttc361 agagattttc aatgatgggt ataagctcag tggattttac aaaatcaaac ctctccagag421 cccagcagaa ttttctgttt attgtgacat gtccgatgga ggaggatgga ctgtaattca481 gagacgatct gatggcagtg aaaactttaa cagaggatgg aaagactatg aaaatggctt541 tggaaatttt gtccaaaaac atggtgaata ttggctgggc aataaaaatc ttcacttctt601 gaccactcaa gaagactaca ctttaaaaat cgaccttgca gattttgaaa aaaatagccg661 ttatgcacaa tataagaatt tcaaagttgg agatgaaaag aatttctacg agttgaatat721 tggggaatat tctggaacag ctggagattc ccttgcgggg aattttcatc ctgaggtgca781 gtggtgggct agtcaccaaa gaatgaaatt cagcacgtgg gacagagatc atgacaacta841 tgaagggaac tgcgcagaag aagatcagtc tggctggtgg tttaacaggt gtcactctgc901 aaacctgaat ggtgtatact acagcggccc ctacacggct aaaacagaca atgggattgt961 ctggtacacc tggcatgggt ggtggtattc tctgaaatct gtggttatga aaattaggcc1021 aaatgatttt attccaaatg taatttaatt gctgctgttg ggctttcgtt tctgcaattc1081 agctttgttt aaagtgattt gaaaaatact cattctgaac atatccatgc gcaatcatga1141 taactgttgt gagtagtgct tttcattctt ctcacttgcc tttgttactt aatgtgcttt1201 cagtacagca gatatgcaat attcaccaaa taaatgtaga ctgtgttaaa aaaaaaaaaa1261 aaaaaaaaaa aaaaaaaaaa aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>94<211>2128
<212>DNA<213>人類(Homo sapiens)<400>941 caagacttct ctgcattttc tgccaaaatc tgtgtcagat ttaagacaca tgcttctgca61 agcttccatg aaggttgtgc aaaaaagttt caatccagag ttgggttcca gctttctgta121 gctgtaagca ttggtggcca caccacctcc ttacaaagca actagaacct gcggcataca181 ttggagagat ttttttaatt ttctggacat gaagtaaatt tagagtgctt tctaatttca241 ggtagaagac atgtccacct tctgattatt tttggagaac attttgattt ttttcatctc301 tctctcccca cccctaagat tgtgcaaaaa aagcgtacct tgcctaattg aaataatttc361 attggatttt gatcagaact gattatttgg ttttctgtgt gaagttttga ggtttcaaac421 tttccttctg gagaatgcct tttgaaacaa ttttctctag ctgcctgatg tcaactgctt481 agtaatcagt ggatattgaa atattcaaaa tgtacagaga gtgggtagtg gtgaatgttt541 tcatgatgtt gtacgtccag ctggtgcagg gctccagtaa tgaacatgga ccagtgaagc601 gatcatctca gtccacattg gaacgatctg aacagcagat cagggctgct tctagtttgg661 aggaactact tcgaattact cactctgagg actggaagct gtggagatgc aggctgaggc721 tcaaaagttt taccagtatg gactctcgct cagcatccca tcggtccact aggtttgcgg781 caactttcta tgacattgaa acactaaaag ttatagatga agaatggcaa agaactcagt841 gcagccctag agaaacgtgc gtggaggtgg ccagtgagct ggggaagagt accaacacat901 tcttcaagcc cccttgtgtg aacgtgttcc gatgtggtgg ctgttgcaat gaagagagcc961 ttatctgtat gaacaccagc acctcgtaca tttccaaaca gctctttgag atatcagtgc1021 ctttgacatc agtacctgaa ttagtgcctg ttaaagttgc caatcataca ggttgtaagt1081 gcttgccaac agccccccgc catccatact caattatcag aagatccatc cagatccctg1141 aagaagatcg ctgttcccat tccaagaaac tctgtcctat tgacatgcta tgggatagca1201 acaaatgtaa atgtgttttg caggaggaaa atccacttgc tggaacagaa gaccactctc1261 atctccagga accagctctc tgtgggccac acatgatgtt tgacgaagat cgttgcgagt1321 gtgtctgtaa aacaccatgt cccaaagatc taatccagca ccccaaaaac tgcagttgct1381 ttgagtgcaa agaaagtctg gagacctgct gccagaagca caagctattt cacccagaca1441 cctgcagctg tgaggacaga tgcccctttc ataccagacc atgtgcaagt ggcaaaacag1501 catgtgcaaa gcattgccgc tttccaaagg agaaaagggc tgcccagggg ccccacagcc1561 gaaagaatcc ttgattcagc gttccaagtt ccccatccct gtcattttta acagcatgct1621 gctttgccaa gttgctgtca ctgttttttt cccaggtgtt aaaaaaaaaa tccattttac1681 acagcaccac agtgaatcca gaccaacctt ccattcacac cagctaagga gtccctggtt1741 cattgatgga tgtcttctag ctgcagatgc ctctgcgcac caaggaatgg agaggagggg1801 acccatgtaa tccttttgtt tagttttgtt tttgtttttt ggtgaatgag aaaggtgtgc1861 tggtcatgga atggcaggtg tcatatgact gattactcag agcagatgag gaaaactgta1921 gtctctgagt cctttgctaa tcgcaactct tgtgaattat tctgattctt ttttatgcag1981 aatttgattc gtatgatcag tactgacttt ctgattactg tccagcttat agtcttccag2041 tttaatgaac taccatctga tgtttcatat ttaagtgtat ttaaagaaaa taaacaccat2101 tattcaagcc aaaaaaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>95<211>5207<212>DNA<213>人類(Homo sapiens)<400>95
1 agagttatat tgtgccattt atggaaaaac tctccccact gctcttggct ttgacagtag61 gaatcaggtt atatatggtc tctcggtttg aagatatttg tcattaaaaa ccagaacaag121 ggctctgaga tagggtcctt tcctgaccta ctctggtaaa gtctttatcc tcaggatgca181 aggataccac cctcttcctg tggaaagtgt cgaatcacat gcagagctct aagtctttca241 gttactttgg agtgcagaac catttcagac atgctgaggg ggactctact gtgcgcggtg301 ctcgggcttc tgcgcgccca gcccttcccc tgtccgccag cttgcaagtg tgtcttccgg361 gacgccgcgc agtgctcggg gggcgacgtg gcgcgcatct ccgcgctggg cctgcccacc421 aacctcacgc acatcctgct cttcggaatg ggccgcggcg tcctgcagag ccagagcttc481 agcggcatga ccgtcctgca gcgcctcatg atctccgaca gccacatttc cgccgttgcc541 cccggcacct tcagtgacct gataaaactg aaaaccctga ggctgtcgcg caacaaaatc601 acgcatcttc caggtgcgct gctggataag atggtgctcc tggagcagtt gtttttggac661 cacaatgcgc taaggggcat tgaccaaaac atgtttcaga aactggttaa cctgcaggag721 ctcgctctga accagaatca gctcgatttc cttcctgcca gtctcttcac gaatctggag781 aacctgaagt tgttggattt atcgggaaac aacctgaccc acctgcccaa ggggttgctt841 ggagcacagg ctaagctcga gagacttctg ctccactcga accgccttgt gtctctggat901 tcggggctgt tgaacagcct gggcgccctg acggagctgc agttccaccg aaatcacatc961 cgttccatcg cacccggggc cttcgaccgg ctcccaaacc tcagttcttt gacgctttcg1021 agaaaccacc ttgcgtttct cccctctgcg ctctttcttc attcgcacaa tctgactctg1081 ttgactctgt tcgagaaccc gctggcagag ctcccggggg tgctcttcgg ggagatgggg1141 ggcctgcagg agctgtggct gaaccgcacc cagctgcgca ccctgcccgc cgccgccttc1201 cgcaacctga gccgcctgcg gtacttaggg gtgactctga gcccgcggct gagcgcgctt1261 ccgcagggcg ccttccaggg ccttggcgag ctccaggtgc tcgccctgca ctccaacggc1321 ctgaccgccc tccccgacgg cttgctgcgc ggcctcggca agctgcgcca ggtgtccctg1381 cgccgcaaca ggctgcgcgc cctgccccgt gccctcttcc gcaatctcag cagcctggag1441 agcgtccagc tcgaccacaa ccagctggag accctgcctg gcgacgtgtt tggggctctg1501 ccccggctga cggaggtcct gttggggcac aactcctggc gctgcgactg tggcctgggg1561 cccttcctgg ggtggctgcg gcagcaccta ggcctcgtgg gcggggaaga gcccccacgg1621 tgcgcaggcc ctggggcgca cgccggcctg ccgctctggg ccctgccggg gggtgacgcg1681 gagtgcccgg gcccccgggg cccgcctccc cgccccgctg cggacagctc ctcggaagcc1741 cctgtccacc cagccttggc tcccaacagc tcagaaccct gggtgtgggc ccagccggtg1801 accacgggca aaggtcaaga tcatagtccg ttctgggggt tttattttct gcttttagct1861 gttcaggcca tgatcaccgt gatcatcgtg tttgctatga ttaaaattgg ccaactcttt1921 cgaaaattaa tcagagagag agcccttggg taaaccaatg ggaaaatctt ctaattactt1981 agaacctgac cagatgtggc tcggagggga atccagaccc gctgctgtct tgctctccct2041 cccctcccca ctcctcctct cttcttcctc ttctctctca ctgccacgcc ttcctttccc2101 tcctcctccc cctctccgct ctgtgctctt cattctcacg ggcccgcaac ccctcctctc2161 tctgtccccg cccgtctctg gaaactgagc ttgacgtttg taaactgtgg ttgcctgcct2221 tcccagctcc acgcggtgtg cgctgacact gccggggggc tggactgtgt tggacccatc2281 cttgccccgc tgtgcctggc ttggcctctg gtggagagag ggacctcttc agtgtctact2341 gagtaagggg acagctccag gccggggctg tctcctgcac agagtaagcc ggtaaatgtt2401 tgtgaaatca atgcgtggat aaaggaacac atgccatcca agtgatgatg gcttttcctg2461 gagggaaagg ataggctgtt gctctatcta attttttgtt tttgtttttg gacagtctag2521 ctctgtggcc caggctggcg tgcagtgggc cgtctcagtt cactgcagcc tccgccctcc2581 aggttcaagt gattctcatg cctcagcgtt ctgagtagct gggattagag gcgtgtgcca2641 ctacacccgg ctaatttttg tactttttaa agtagagacg ggctttgcca tattggcctg2701 gctgatctca aactcctggt cttgaactcc tggccacaag tgatctgccc gccttagcct2761 cccaaagtgc tgggattaca ggcgcaagcc actacacctg ccctcttcat cgaattttat2821 ttgagaagta gagctcttgc cattttttcc cttgctccat ttttctcact ttatgtctct
2881 ctgacctatg ggctacttgg gagagcactg gactccattc atgcatgagc attttcagga2941 taagcgactt ctgtgaggct gagagaggaa gaaaacacgg agccttccct ccaggtgccc3001 agtgtaggtc cagcgtgttt cctgagcctc ctgtgagttt ccacttgctt tacatccatg3061 caacatgtca ttttgaaact ggattgattt gcatttcctg gaactctgcc acctcatttc3121 acaagcattt atggagcagt taacatgtga ctggtattca tgaatataat gataagcttg3181 attctagttc agctgctgtc acagtctcat ttgttcttcc aactgaaagc cgtaaaacct3241 ttgttgcttt aattgaatgt ctgtgcttat gagaggcagt ggttaaaaca ttttctggcg3301 agttgacaac tgtgggttca aatcccagct ctaccactta ctaactgcat gggactttgg3361 gtaagacacc tgcttacatt ctctaagcct tggtttcctg aaccttaaaa caggataaca3421 tagtacctgc ttcatagagt tttgtgagaa ttaaaggcaa taaagcatat aatgacttag3481 cccagcggcc tgcagacaat acatgttaat gaatgttagc tattattact aaagatgagc3541 aattattatt ggcatcatga tttctaaaga agagctttga gttggtattt ttctctgtgt3601 ataagggtaa gtccgaactt tctcatactg gaggttacat tcacatcagt ctgtcttccc3661 ctgcggatgg cctcagccct gggtggccag gctctgtgct cacagtccag agcaatggat3721 cctccaacac caccaggtgg atgtggagca ggagagctgg atcgtggcat ttgtttctgg3781 gttctgcagt tgggagttgg tttctgggtt ctccattggt ctacttgtct agtcccatac3841 cagactcacg gtctccatta ttggagcttt aataattttt ggtatagggt catctctcca3901 ccttgttttt cttctattct tggttctttg caattctatg aatatttcag ggtcagcatg3961 tcaactccat tgaaaaaccc tgctgggatt ttaatagaac ttacagctca cgcctgtaat4021 cccagcactt tgggaggctg aggtgggtgg atcacaggtc aggagtttga gaacagctgg4081 ccaagatggt gaaaccccgt ctctactaaa aatacaaaaa ttagctgggt gcggtggcag4141 gtgcctgtag tcccagctac ttgggacacc gaggcaggag aatcacttga acccgggagg4201 cggaggttgc agtgagccga gatcgtgcca ctgcactcta gcctgggcga cagagcgaga4261 ctccatctca aaaaaaaaga aaaagaaaat tgcagtaaat ttaaaactaa tttggggaag4321 aatctgtatt tttacaatac ctagtgttct tgccagtaag catggttcat cttcccattt4381 atttacgtca ttttaaatct ttcagtgatg ttttagaatt ttttttataa aaaccttcac4441 tataagaaca gaaaaccaaa caccgcatgt tctcactcat aggtgggaat tgaacaatga4501 gaacacttgg acacagggcg gggaacgtca cacgcctgga ctgttggggg ggtggctggg4561 agagggatag tgttaggaga aatacctaat gtaaatgacg agttaatggt gcagccaacc4621 aacctggcac atgtattcat atgtaacaaa cctgcacgtt gtgcacatgt accctagaac4681 ttaaagtata ttaaaaaaag aaaccttggc actgattttg ttagatttat tcctaggtat4741 ccttcctctt ttttgatttg tcattgctat tgtagatggc atctttttaa aaagttatat4801 tttctaaagc aaaaaataaa aaaagttgta tttctaattt ttattaccaa tatataagaa4861 tgtaatttat ttttacataa ttatcttatg tctagtaata attctgataa tttgcttctt4921 cctattaaaa ccttacaccc attattgatt tatttttctg ttttaaaata tcttcctgca4981 ctggctaaaa cctccactat aatgttgagc agaacagtga ggcatcctta gaactatctt5041 ggttgcaaag ggtaggtctc taatgtttca tcaataaatg tgatgtttct agtctgagtt5101 tgctaagtat attttaaaat aatcagtaaa gttagatttt atccattttt atcttaacta5161 ttgagatgct catatcattt ttcttcttca atgtgttaaa atggtga<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>96<211>2964<212>DNA<213>人類(Homo sapiens)<400>96
1 cagagccacg ggcgcccgcc ccgccccgcg ccgccccgcg ccggctccgc agctcgcgcc61 cgcccgcctg ccggcccgcc cggcgccggg ccatggcgct gctgcgggat gtgtcgctgc121 aggacccgcg ggaccgcttc gagctgctgc agcgcgtggg ggccgggacc tatggcgacg181 tctacaaggc ccgcgacacg gtcacgtccg aactggccgc cgtgaagata gtcaagctag241 acccagggga cgacatcagc tccctccagc aggaaatcac catcctgcgt gagtgccgcc301 accccaatgt ggtggcctac attggcagct acctcaggaa tgaccgcttg tggatctgca361 tggagttctg cggagggggc tccctgcagg agatttacca tgccactggg cccctggagg421 agcggcagat tgcctacgtc tgccgagagg cactgaaggg gctccaccac ctgcattctc481 aggggaagat ccacagagac atcaagggag ccaaccttct cctcactctc cagggagatg541 tcaaactggc tgactttggg gtgtcaggcg agctgacagc gtctgtggcc aagaggaggt601 ctttcattgg gactccctac tggatggctc ccgaggtggc tgctgtggag cgcaaaggtg661 gctacaatga gctatgtgac gtctgggccc tgggcatcac tgccattgag ctgggcgagc721 tgcagccccc tctgttccac ctgcacccca tgagggccct gatgctcatg tcgaagagca781 gcttccagcc gcccaaactg agagataaga ctcgctggac ccagaatttc caccactttc841 tcaaactggc cctgaccaag aatcctaaga agaggccgac agcagagaag ctcctgcagc901 acccgttcac gactcagcag ctccctcggg ccctcctcac acagctgctg gacaaagcca961 gtgaccctca tctggggacc ccctcccctg aggactgtga gctggagacc tatgacatgt1021 ttccagacac cattcactcc cgggggcagc acggcccagc cgagaggacc ccctcggaga1081 tccagtttca ccaggtgaaa tttggcgccc cacgcaggaa ggaaactgac ccactgaatg1141 agccgtggga ggaagagtgg acactactgg gaaaggaaga gttgagtggg agcctgctgc1201 agtcggtcca ggaggccctg gaggaaagga gtctgactat tcggtcagcc tcagaattcc1261 aggagctgga ctccccagac gataccatgg gaaccatcaa gcgggccccg ttcctagggc1321 cactccccac tgaccctcca gcagaggagc ctctgtccag tcccccagga accctgcccc1381 cacctccttc aggccccaac agctccccac tgctgcccac ggcctgggcc accatgaagc1441 agcgggagga tcctgagagg tcatcctgcc acgggctccc cccaactccc aaggtgcata1501 tgggcgcctg cttctccaag gtcttcaatg gctgccccct gcggatccac gctgctgtca1561 cctggattca ccctgttact cgggaccagt tcctggtggt aggggccgag gaaggcatct1621 acacactcaa cctgcatgaa ctgcatgagg atacgctgga gaagctgatt tcacatcgct1681 gctcctggct ctactgcgtg aacaacgtgc tgctgtcact ctcagggaaa tccacgcaca1741 tctgggccca tgacctccca ggcctgtttg agcagcggag gctacagcaa caggttcccc1801 tctccatccc caccaaccgc ctcacccagc gcatcatccc caggcgcttt gctctgtcca1861 ccaagattcc tgacaccaaa ggctgcttgc agtgtcgtgt ggtgcggaac ccctacacgg1921 gtgccacctt cctgctggcc gccctgccca ccagcctgct cctgctgcag tggtatgagc1981 cgctgcagaa gtttctgctg ctgaagaact tctccagccc tctgcccagc ccagctggga2041 tgctggagcc gctggtgctg gatgggaagg agctgccgca ggtgtgtgtt ggggccgagg2101 ggcctgaggg gcccggctgc cgcgtcctgt tccatgtcct gcccctggag gctggcctga2161 cgcccgacat cctcatccca cctgagggga tcccaggctc ggcccagcag gtgatccagg2221 tggacaggga cacaatccta gtcagctttg aacgctgtgt gaggattgtc aacatgcagg2281 gcgagcccac ggccacactg gcacctgagc tgacctttga tttccccatc gagactgtgg2341 tgtgcctgca ggacagtgtg ctggccttct ggagccatgg gatgcaaggc cgaagcctgg2401 ataccaatga ggtgacccag gagatcacag atgaaacaag gatcttccga gtgcttgggg2461 cccacagaga catcatcctg gagagcattc ccactgacaa cccagaggcg cacagcaacc2521 tctacatcct cacgggccac cagagcacct actaagagca gcgggcctgt ccaggggctc2581 cccgccccac cccacgcctt agctgcaggc ccttttgggc aaaggggccc atcctagacc2641 agaggagccc aggccctggc cctgctgggg ctgaaggtca gaagtaatcc tgagaaatgt2701 ttcaggcctg gggagggagg ggagcccccg acgcctctgc aataactgga ccagggggag2761 ctgctgtcac tcccccatcc ccgaggcagc ccagtcccta gtgcccaagg cagggaccct2821 gggcctgggc catccattcc attttgttcc acatttcctt tctactcttt ctgccaagag
2881 cctgcccctg catttgtcct gggaaacacg gtatttaaga gagaactata ttggtattaa2941 agctggtttg ttttaaaaaa aaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>97<211>2512<212>DNA<213>人類(Homo sapiens)<400>971 ggctggtgca aggagccaca gtgggctgcc tggggggctg atgccaccat tccaggagcc61 tcggtgaaga gaggatatcc atctgtgtag ccgcttctct atacgggatt cgagctccat121 ggcagcccgt ctgctcctcc tgggcatcct tctcctgctg ctgcccctgc ccgtccctgc181 cccgtgccac acagccgcac gctcagagtg caagcgcagc cacaagttcg tgcctggtgc241 atggctggcc ggggagggtg tggacgtgac cagcctccgc cgctcgggct ccttcccagt301 ggacacacaa aggttcctgc ggcccgacgg cacctgcacc ctctgtgaaa atgccctaca361 ggagggcacc ctccagcgcc tgcctctggc gctcaccaac tggcgggccc agggctctgg421 ctgccagcgc catgtaacca gggccaaagt cagctccact gaagctgtgg cccgggatgc481 ggctcgtagc atccgcaacg actggaaggt cgggctggac gtgactccta agcccaccag541 caatgtgcat gtgtctgtgg ccggctcaca ctcacaggca gccaactttg cagcccagaa601 gacccaccag gaccagtaca gcttcagcac tgacacggtg gagtgccgct tctacagttt661 ccatgtggta cacactcccc cgctgcaccc tgacttcaag agggccctcg gggacctgcc721 ccaccacttc aacgcctcca cccagcccgc ctacctcagg cttatctcca actacggcac781 ccacttcatc cgggctgtgg agctgggtgg ccgcatatcg gccctcactg ccctgcgcac841 ctgcgagctg gccctggaag ggctcacgga caacgaggtg gaggactgcc tgactgtcga901 ggcccaggtc aacataggca tccacggcag catctctgcc gaagccaagg cctgtgagga961 gaagaagaag aagcacaaga tgacggcctc cttccaccaa acctaccggg agcgccactc1021 ggaagtggtt ggcggccatc acacctccat taacgacctg ctgttcggga tccaggccgg1081 gcccgagcag tactcagcct gggtaaactc gctgcccggc agccctggcc tggtggacta1141 caccctggaa cccctgcacg tgctgctgga cagccaggac ccgcggcggg aggcactgag1201 gagggccctg agtcagtacc tgacggacag ggctcgctgg agggactgca gccggccgtg1261 cccaccaggg cggcagaaga gcccccgaga cccatgccag tgtgtgtgcc atggctcagc1321 ggtcaccacc caggactgct gccctcggca gaggggcctg gcccagctgg aggtgacctt1381 catccaagca tggggcctgt ggggggactg gttcactgcc acggatgcct atgtgaagct1441 cttctttggt ggccaggagc tgaggacgag caccgtgtgg gacaataaca accccatctg1501 gtcagtgcgg ctggattttg gggatgtgct cctggccaca ggggggcccc tgaggttgca1561 ggtctgggat caggactctg gcagggacga tgacctcctt ggcacctgtg atcaggctcc1621 caagtctggt tcccatgagg tgagatgcaa cctgaatcat ggccacctaa aattccgcta1681 tcatgccagg tgcttgcccc acctgggagg aggcacctgc ctggactatg tcccccaaat1741 gcttctgggg gagcctccag gaaaccggag tggggccgtg tggtgagaac agtgagcttg1801 gaaaggacca gtatgcttgg actgaagggg ttctcacagt gggagccagg gctgtcttcg1861 tattcccatt agaccaagct tgtccaaccc gaggcccgca tgcggcccag gatggctttg1921 aatgcggccc aacgcaaatt cgcaaacttt cttaaaacat tatgagtttc tttttgctat1981 tttttttttt tttttagctc atcggctatc gttagtgcta gtggatttta catgtggccc2041 aacacaattc ttcttccaac gtggcccaga gaagccaaaa gattggatac gcatcagaca2101 gatggaaaag ggagattcag actgtttttc agggaggtgg ctgggtttac acgctaatcc2161 cgattcaccc tgtccaaact gcctaagccc tccgccattc tcaagccctg cagtcacagc
2221 tacacagatc acagcttcag ccaggagctg ggcagaaggc caagaggctg ttcccaccag2281 gctgctcagg gctggtcttt taggaccctt cccttgagcc ctctatggtg tggcaaagcc2341 ttcattgcct taactggagc cccatcagct ccagctgctc tgtcttcttt gcccacaatg2401 ctttgcccct gagacaaatg gaggcctgtc ctgacctgtc tcaccatgta catagcttga2461 taaagggcca ataaatatga tgttatggtg aaaaaaaaaa aaaaaaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>98<211>1949<212>DNA<213>人類(Homo sapiens)<400>981 ttgaagatct ctcagttaag tctacatgaa aaggatggtt tcttggagct tccacaaact61 taaaaccatg aaacatctat tattgctact attgtgtgtt tttctagtta agtcccaagg121 tgtcaacgac aatgaggagg gtttcttcag tgcccgtggt catcgacccc ttgacaagaa181 gagagaagag gctcccagcc tgaggcctgc cccaccgccc atcagtggag gtggctatcg241 ggctcgtcca gccaaagcag ctgccactca aaagaaagta gaaagaaaag cccctgatgc301 tggaggctgt cttcacgctg acccagacct gggggtgttg tgtcctacag gatgtcagtt361 gcaagaggct ttgctacaac aggaaaggcc aatcagaaat agtgttgatg agttaaataa421 caatgtggaa gctgtttccc agacctcctc ttcttccttt cagtacatgt atttgctgaa481 agacctgtgg caaaagaggc agaagcaagt aaaagataat gaaaatgtag tcaatgagta541 ctcctcagaa ctggaaaagc accaattata tatagatgag actgtgaata gcaatatccc601 aactaacctt cgtgtgcttc gttcaatcct ggaaaacctg agaagcaaaa tacaaaagtt661 agaatctgat gtctcagctc aaatggaata ttgtcgcacc ccatgcactg tcagttgcaa721 tattcctgtg gtgtctggca aagaatgtga ggaaattatc aggaaaggag gtgaaacatc781 tgaaatgtat ctcattcaac ctgacagttc tgtcaaaccg tatagagtat actgtgacat841 gaatacagaa aatggaggat ggacagtgat tcagaaccgt caagacggta gtgttgactt901 tggcaggaaa tgggatccat ataaacaggg atttggaaat gttgcaacca acacagatgg961 gaagaattac tgtggcctac caggtgaata ttggcttgga aatgataaaa ttagccagct1021 taccaggatg ggacccacag aacttttgat agaaatggag gactggaaag gagacaaagt1081 aaaggctcac tatggaggat tcactgtaca gaatgaagcc aacaaatacc agatctcagt1141 gaacaaatac agaggaacag ccggtaatgc cctcatggat ggagcatctc agctgatggg1201 agaaaacagg accatgacca ttcacaacgg catgttcttc agcacgtatg acagagacaa1261 tgacggctgg ttaacatcag atcccagaaa acagtgttct aaagaagacg gtggtggatg1321 gtggtataat agatgtcatg cagccaatcc aaacggcaga tactactggg gtggacagta1381 cacctgggac atggcaaagc atggcacaga tgatggtgta gtatggatga attggaaggg1441 gtcatggtac tcaatgagga agatgagtat gaagatcagg cccttcttcc cacagcaata1501 gtccccaata cgtagatttt tgctcttctg tatgtgacaa catttttgta cattatgtta1561 ttggaatttt ctttcataca ttatattcct ctaaaactct caagcagacg tgagtgtgac1621 tttttgaaaa aagtatagga taaattacat taaaatagca catgattttc ttttgttttc1681 ttcatttctc ttgctcacca agaagtaaca aaagtatagt tttgacagag ttggtgttca1741 taatttcagt tctagttgat tgcgagaatt ttcaaataag gaagaggggt cttttatcct1801 tgtcgtagga aaaccatgac ggaaaggaaa aactgatgtt taaaagtcca cttttaaaac1861 tatatttatt tatgtaggat ctgtcaaaga aaacttccaa aaagatttat taattaaacc1921 agactctgtt gcaataaaaa aaaaaaaaa
<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>99<211>2764<212>DNA<213>人類(Homo sapiens)<400>991 ctctaaagct tagagccaag atggcgggat ccaggcaaag gggtctccgg gccagagttc61 ggccgctgtt ctgcgccttg ctgctgtcac tcggtcgctt cgtccggggc gacggcgtgg121 gaggagaccc cgcggtcgcg ttgccacatc gccgtttcga gtacaaatac agcttcaagg181 ggccgcacct ggtgcagagc gacgggaccg tgcccttctg ggcccacgcg gggaatgcta241 ttccaagttc agatcaaatt cgagtagcac catctttaaa aagccaaaga ggctcagtgt301 ggacaaagac aaaagcggcc tttgagaact gggaagttga ggtgacattt cgagtgactg361 gaagaggtcg aattggagct gatggcctag caatttggta tgcagaaaat caaggcttgg421 agggccctgt gtttggatca gctgatctgt ggaatggtgt tggaatattt tttgattctt481 ttgacaatga tggaaagaaa aataatcctg ctatagtaat tataggcaac aatggacaaa541 tccattatga ccatcaaaat gacggggcta gtcaagcttt ggcaagttgc cagagggact601 tccgcaacaa accctatcct gtccgagcaa agattaccta ttaccagaac acactgacag661 taatgatcaa taatggcttt acaccagata aaaatgatta tgaattttgt gccaaagtgg721 aaaatatgat tatccctgca caagggcatt ttggaatatc tgctgcaact ggaggtcttg781 cagatgacca tgatgtcctt tcttttctga ctttccagtt gactgaacct ggaaaagagc841 cgcccacacc agataaagaa atttcggaaa aggaaaaaga aaagtatcag gaggaatttg901 agcactttca acaagaattg gataaaaaaa aagaggaatt ccagaagggc caccccgacc961 tccaagggca gcctgcggag gaaatatttg agagtgtagg agatcgagag ctaagacaag1021 tctttgaagg acagaatcgt attcatcttg aaatcaagca gctgaaccgg cagttagata1081 tgattcttga tgaacagaga agatatgtct cttccttaac agaggaaatc tctaaaagag1141 gagcaggaat gcctgggcag catgggcaga ttactcaaca agaactggat actgttgtga1201 aaactcagca tgagattctg agacaagtaa atgaaatgaa aaattccatg agtgaaaccg1261 tcagactggt cagtggaatg cagcaccctg gctctgctgg aggcgtctat gagacaacac1321 agcacttcat tgacatcaaa gagcacctgc acatagtaaa gagggacata gataacttag1381 tgcagcgaaa tatgccatca aatgaaaagc cgaaatgccc agaactacca ccatttccat1441 catgtttgtc tacggtccac ttcattatat ttgttgtggt gcaaactgta ttattcattg1501 gttatatcat gtataggtct cagcaagaag cagctgccaa aaaattcttt tgactaccat1561 tttcctgtgt acttcatcta tttgtgtaca aaatgatgtc gttttgaggg aatttaagta1621 tttaaattgc ttcatagtct aaattattaa ttttcttaat aaaataactg tttaaacatt1681 gatttgcagt taagaataaa ccttaaagca aagacaacca cattttaatt tgttcacagt1741 atgtaaatct gtctaaattt cagtgaattt ctggtcagta tgatgcagcc tctgagcaga1801 tattgaccag taagagggta aataaagtgg gggcaacccc tggatatgaa tgttaccccc1861 taagtctcca atattgcagg tttccctgta taacgtaaac acacttgccc tcatgcctcc1921 cagaatatga ggtctaatta agaagtccca tcaggtttat tttgtaacca aagtcttttt1981 tagaggtcag acttcctaat caaaggcctg ggcctgcagt cctttcatct taatgcaact2041 tcctttgaaa tcaaagaata ttttgtctga gagctttaag gatctggtaa tagacttcaa2101 aatgttaagt gaaatttttt ttcctctatt tatcaatgat atatttcact tttaaaggaa2161 attttggagg aaaatatagc tgctttttgc ctaaaaaacc ttgtgggtgg aaatattcct2221 ctgagaatgg cttttatagg tattttgcct ggtaatgtat tcattcatga ttgcccatat2281 tcttgaatgt ttcttcattc caatggggtc aggtcaatat tatgaaaata atttttatat2341 ttatatttgt aactaagaat ttatttctcc ctttactaca cgatgtaaat tcacgtcaaa
2401 ttcgatgatc tgaggattta aattcacaaa acctgccact acattctggt ttacattagt2461 tacttcatgc tggctggggt tagtgaccat ttgcatactc ttttaaatca aggaggctgt2521 agtagaggca gttttaagat tcttgaaggc aaaatttgaa aaacagtgaa tacttctaat2581 tgtttccttt tagtgccaga actaagacat tgtgaagcac ttgttagtaa acttaacctt2641 gaaatgtcag actggaagga gtttttatgt ctttgtgcat acttctgggt attacagaaa2701 cagtctgtaa ataacatttt aagatgcaaa tttaattctg ttcacagctg atttatactg2761 attt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>100<211>3158<212>DNA<213>人類(Homo sapiens)<400>1001 aaaccggaac ggggcccaac ttctggggcc tggagaaggg aaacgaagtc ccccccggtt61 tcccgaggtt gcctttcctc gggcatcctt ggtttcggcg ggacttcgca gggcggatat121 aaagaacggc gcctttggga agaggcggag accggcttta aagaaagaag tcttggtcct181 gcggcttggg cgaggcaagg gcgaggcaag ggcgctttct gccgacgctc cccgtggccc241 tacgatcccc cgcgcgtccg ccgctgttct aaggagagaa gtgggggccc cccaggctcg301 cgcgtggagc gaagcagcat gggcagtcgg tgcgcgctgg ccctggcggt gctctcggcc361 ttgctgtgtc aggtctggag ctctggggtg ttcgaactga agctgcagga gttcgtcaac421 aagaaggggc tgctggggaa ccgcaactgc tgccgcgggg gcgcggggcc accgccgtgc481 gcctgccgga ccttcttccg cgtgtgcctc aagcactacc aggccagcgt gtcccccgag541 ccgccctgca cctacggcag cgccgtcacc cccgtgctgg gcgtcgactc cttcagtctg601 cccgacggcg ggggcgccga ctccgcgttc agcaacccca tccgcttccc cttcggcttc661 acctggccgg gcaccttctc tctgattatt gaagctctcc acacagattc tcctgatgac721 ctcgcaacag aaaacccaga aagactcatc agccgcctgg ccacccagag gcacctgacg781 gtgggcgagg agtggtccca ggacctgcac agcagcggcc gcacggacct caagtactcc841 taccgcttcg tgtgtgacga acactactac ggagagggct gctccgtttt ctgccgtccc901 cgggacgatg ccttcggcca cttcacctgt ggggagcgtg gggagaaagt gtgcaaccct961 ggctggaaag ggccctactg cacagagccg atctgcctgc ctggatgtga tgagcagcat1021 ggattttgtg acaaaccagg ggaatgcaag tgcagagtgg gctggcaggg ccggtactgt1081 gacgagtgta tccgctatcc aggctgtctc catggcacct gccagcagcc ctggcagtgc1141 aactgccagg aaggctgggg gggccttttc tgcaaccagg acctgaacta ctgcacacac1201 cataagccct gcaagaatgg agccacctgc accaacacgg gccaggggag ctacacttgc1261 tcttgccggc ctgggtacac aggtgccacc tgcgagctgg ggattgacga gtgtgacccc1321 agcccttgta agaacggagg gagctgcacg gatctcgaga acagctactc ctgtacctgc1381 ccacccggct tctacggcaa aatctgtgaa ttgagtgcca tgacctgtgc ggacggccct1441 tgctttaacg ggggtcggtg ctcagacagc cccgatggag ggtacagctg ccgctgcccc1501 gtgggctact ccggcttcaa ctgtgagaag aaaattgact actgcagctc ttcaccctgt1561 tctaatggtg ccaagtgtgt ggacctcggt gatgcctacc tgtgccgctg ccaggccggc1621 ttctcgggga ggcactgtga cgacaacgtg gacgactgcg cctcctcccc gtgcgccaac1681 gggggcacct gccgggatgg cgtgaacgac ttctcctgca cctgcccgcc tggctacacg1741 ggcaggaact gcagtgcccc cgtcagcagg tgcgagcacg caccctgcca caatggggcc1801 acctgccacc agaggggcca cggctatgtg tgcgaatgtg cccgaagcta cgggggtccc1861 aactgccagt tcctgctccc cgagctgccc ccgggcccag cggtggtgga cctcactgag
1921 aagctagagg gccagggcgg gccattcccc tgggtggccg tgtgcgccgg ggtcatcctt1981 gtcctcatgc tgctgctggg ctgtgccgct gtggtggtct gcgtccggct gaggctgcag2041 aagcaccggc ccccagccga cccctgccgg ggggagacgg agaccatgaa caacctggcc2101 aactgccagc gtgagaagga catctcagtc agcatcatcg gggccacgca gatcaagaac2161 accaacaaga aggcggactt ccacggggac cacagcgccg acaagaatgg cttcaaggcc2221 cgctacccag cggtggacta taacctcgtg caggacctca agggtgacga caccgccgtc2281 agggacgcgc acagcaagcg tgacaccaag tgccagcccc agggctcctc aggggaggag2341 aaggggaccc cgaccacact caggggtgga gaagcatctg aaagaaaaag gccggactcg2401 ggctgttcaa cttcaaaaga caccaagtac cagtcggtgt acgtcatatc cgaggagaag2461 gatgagtgcg tcatagcaac tgaggtgtaa aatggaagtg agatggcaag actcccgttt2521 ctcttaaaat aagtaaaatt ccaaggatat atgccccaac gaatgctgct gaagaggagg2581 gaggcctcgt ggactgctgc tgagaaaccg agttcagacc gagcaggttc tcctcctgag2641 gtcctcgacg cctgccgaca gcctgtcgcg gcccggccgc ctgcggcact gccttccgtg2701 acgtcgccgt tgcactatgg acagttgctc ttaagagaat atatatttaa atgggtgaac2761 tgaattacgc ctaagaagca tgcactgcct gagtgtatat tttggattct tatgagccag2821 tcttttcttg aattagaaac acaaacactg cctttattgt cctttttgat acgaagatgt2881 gctttttcta gatggaaaag atgtgtgtta ttttttggat ttgtaaaaat atttttcatg2941 atatctgtaa agcttgagta ttttgtgatg ttcgtttttt ataatttaaa ttttggtaaa3001 tatgtacaaa ggcacttcgg gtctatgtga ctatattttt ttgtatataa atgtatttat3061 ggaatattgt gccaatgtta tttgagtttt ttactgtttt gttaatgaag aaattccttt3121 ttaaaatatt tttccaaaat aaattttatg aggaattc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>102<211>1678<212>DNA<213>人類(Homo sapiens)<400>1021 gcatatactg tcatcatctt ggaaagaaaa ggctgagaac gtaaaactga ggacagagga61 ggaaagcagg gtgacccctg atgttgccct agaaaatgga aaacaaaaca cagcaaaaca121 gaaaaacaga agatctgact ctgcctttag ccaggaaaac agtttggggg agtaaaaagt181 attagggaaa agagtgggca ttttgcctgg aaaaaaggtt tctagagcca tctgggcttt241 ccgggaacct ggaccagact ctggcccagt aggatgtccc cgtgtcctcc ccagcagagc301 aggaacaggg tgatacagct gtccacttca gagctaggag agatggaact gacttggcag361 gagatcatgt ccatcaccga gctgcagggt ctgaatgctc caagtgagcc atcatttgag421 ccccaagccc cagctccata ccttggacct ccaccaccca caacttactg cccctgctca481 atccacccag attctggctt cccacttcct ccaccacctt atgagctccc agcatccaca541 tcccatgtcc cagatccccc atactcctat ggcaacatgg ccataccagt ctccaagcca601 ctgagcctct caggcctgct cagtgagccg ctccaagacc ccttagccct cctggacatt661 gggctgccag cagggccacc taagccccaa gaagacccag aatccgactc aggattatcc721 ctcaactata gcgatgctga atctcttgag ctggagggga cagaggctgg tcggcggcgc781 agcgaatatg tagagatgta cccagtggag tacccctact cactcatgcc caactccttg841 gcccactcca actatacctt gccagctgct gagaccccct tggccttaga gccctcctca901 ggccctgtgc gggctaagcc cactgcacgg ggggaggcag ggagtcggga tgaacgtcgg961 gccttggcca tgaagattcc ttttcctacg gacaagattg tcaacttgcc ggtagatgac1021 tttaatgagc tattggcaag gtacccgctg acagagagcc agctagcgct agtccgggac
1081 atccgacgac ggggcaaaaa caaggtggca gcccagaact gccgcaagag gaagctggaa1141 accattgtgc agctggagcg ggagctggag cggctgacca atgaacggga gcggcttctc1201 agggcccgcg gggaggcaga ccggaccctg gaggtcatgc gccaacagct gacagagctg1261 taccgtgaca ttttccagca ccttcgggat gaatcaggca acagctactc tcctgaagag1321 tacgcgctgc aacaggctgc cgatgggacc atcttccttg tgccccgggg gaccaagatg1381 gaggccacag actgagctgg cccagagggg tggaactgct gatgggattt ccttcattcc1441 cttctgataa aggtactccc caaccctgag tcccagaagg agctgagttc tctagaccag1501 aagaggatga caatggcaac aagtgtttgg aagttccaag gtgtgttcaa agaggcttgc1561 cttgagggag ggctggaatc tgtcttccct gactcggctc ctcaggtctt tagcctccac1621 cttgtctaag ctttggtcta taaagtgcgc tacagaaaaa aaaaaaaaaa aaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>101<211>3026<212>DNA<213>人類(Homo sapiens)<400>1011 tcgacccacg cgtccggatt gaggggttga ctgagcgttg cgagccttag ctttctcccg61 aacgccagcg ctgaggacac gatgtcgcgg ctctcccgct cactgctttg ggccgccacc121 tgcctgggcg tgctctgcgt gctgtccgcg gacaagaaca cgacccagca cccgaacgtg181 acgactttag cgcccatctc caacgtaacc tcggcgccgg tgacgtccct cccgctggtc241 accactccgg caccagaaac ctgtgaaggt cgaaacagct gcgtttcctg ttttaatgtt301 agcgttgtta atactacctg cttttggata gaatgtaaag atgagagcta ttgttcacat361 aactcaacag ttagtgattg tcaagtgggg aacacgacag acttctgttc cgtttccacg421 gccactccag tgccaacagc caattctaca gctaaaccca cagttcagcc ctccccttct481 acaacttcca agacagttac tacatcaggt acaacaaata acactgtgac tccaacctca541 caacctgtgc gaaagtctac ctttgatgca gccagtttca ttggaggaat tgtcctggtc601 ttgggtgtgc aggctgtaat tttctttctt tataaattct gcaaatctaa agaacgaaat661 taccacactc tgtaaacaga cccattgaat taataaggac tggtgattca tttgtgtaac721 tcactgaagc caaaatacta tcttttaaga tgtcccacat ggaagacgct attccaggat781 ctttaaattt ccatggatgc atataggatg tttgggagca tcatccgtga agaaaaaatc841 aattaaatca ttgtgttcaa caggaatatt taaaatattc tgcatgaatc ctgtggctgt901 cttattttaa atagctgctg ctgtgggatt atattttttt tccttaacat gccaaatata961 actttctgaa agtgatggaa aatgttgtct tgtgcagaca acatcatggc tcttggcagt1021 ttaaatttag taattttaat ttagtgaaca gaattgagaa gaacgtgcca aatgagaatc1081 aattaggtgg atttttggct gtcatttcaa aagtggaata aatttattaa tttagtagta1141 ctaaatggta tccttagatt aaaattttgt gcttgataac agctgttttt tctacattag1201 aaataagatg ccacacaagg aactacattc cagatttaaa gaaatgaaag gataccatta1261 gtgtgtataa cagattattg ttcatacttg taaagcatct tatgtcattg agaatataaa1321 gaacagtgcc ttagaagaca gtgaaaggta agctctagct taatgtctat gatttgttct1381 ttgacattaa ggaaggtaag gattggtcag aggatgtaac ttgatgtgag cagtagtaaa1441 cctgttttag atatcatact gttaatattt tattgaaaat ttatttcaga gcggagaaac1501 ttaagctaaa gtctgttata cagaattgaa agccttcgta tcttgaacct cccaacattt1561 ttcttatggc tgttgaaaag tatagagcta aattgattta attacacttt cctttgtact1621 ttaaaaaaaa gtatgctagc actattgtac cttgaaagga tttccaccag actgtcttga1681 gtagtgactt ctttggtgag gcaagaagga tatacattat tttagaatca tttactattt
1741 aaatgagaca atcatattat tttagaatca tttattttaa atgagacaat cattttaagt1801 tttaagataa cagaagtgac caatgtaatt tcacaacacc taaggatttt ttggttgatc1861 aggttactgt agatttttac tgattgtcct ggatgaatag actgtgcttt ttctttttct1921 ctcccttcct tcttggtttc ccatagtata ataagcatgc atactttaac ttctatagtt1981 ttctccttta gagggtcgtc ttcagtttta gaggtttact tctcccttgc ctttgactca2041 ttggactagt gcagaggctt taagtagttt aaaatgggct tttgcttttc taggtcatta2101 acgtttttta tttagtttct ttagccaata gtggctgagt ttcgcacttg attttcaata2161 ttttatagta agaaatgaca aactgctttg tttcatttca taaacaaact ctgcatttag2221 ataactatta aaggttgtta agatgaagat ttactgtttc tttgttactc gttggtacag2281 ctgtttgttt tacttgcaca tttgtacata tacttaatgt tttcaagtgc cttaattgtt2341 taaaatctct ggcttcaaag tttcttgggg aaaggtcggt ttacctcaca ttttttgttt2401 ccattagtaa tattctaggt acctcacaaa atgtattatg gtgccatggc tgttagtttt2461 tagtgagtgc tgtaggatta attcgaaaat aggcagaatt ccattcctcc caaggtggca2521 aaaattagct atactgatgt aattgtcatt tacctgggta tgaattccct gacacacatt2581 catgtcaaca tatgtagcaa attttgtgaa aacataacaa tttgaagctt ctgtaatttt2641 gagcactgct ctaacaacaa gcataatata aaattagtta gattttgcaa gtctacaaat2701 gagctcttgc aacagaactc acagcctttt tacttttttc ccctaacttt agcaatgtag2761 tatcttgagc cattaatttt tgggtttttt taaaatccag aaggtatata gaaacctttt2821 cagatttttc atctgatttg ttcttgcaga tgttcttcta tcaaatacct tattttacct2881 tacagatatt tgttgcacag gcagatactg ctgtatttag acatttctat ttcagttcat2941 taaaaactgc aaaaccaatc tgtatcatgt accaaactga cttaaaataa atctacatgt3001 ttattgaaaa aaaaaaaaaa aaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>103<211>1502<212>DNA<213>人類(Homo sapiens)<400>1031 cctgcgtccc cgccccgcgc agccgccgcg ctcctgcgct ccgaggtccg aggttcccga61 gatgaaggtc tggctgctgc ttggtcttct gctggtgcac gaagcgctgg aggatgttac121 tggccaacac cttcccaaga acaagcgtcc aaaagaacca ggagagaata gaatcaaacc181 taccaacaag aaggtgaagc ccaaaattcc taaaatgaag gacagggact cagccaattc241 agcaccaaag acgcagtcta tcatgatgca agtgctggat aaaggtcgct tccagaaacc301 cgccgctacc ctgagtctgc tggcggggca aactgtagag cttcgatgta aagggagtag361 aattgggtgg agctaccctg cgtatctgga cacctttaag gattctcgcc tcagcgtcaa421 gcagaatgag cgctacggcc agttgactct ggtcaactcc acctcggcag acacaggtga481 attcagctgc tgggtgcagc tctgcagcgg ctacatctgc aggaaggacg aggccaaaac541 gggctccacc tacatctttt ttacagagaa aggagaactc tttgtacctt ctcccagcta601 cttcgatgtt gtctacttga acccggacag acaggctgtg gttccttgtc gggtgaccgt661 gctgtcggcc aaagtcacgc tccacaggga attcccagcc aaggagatcc cagccaatgg721 aacggacatt gtttatgaca tgaagcgggg ctttgtgtat ctgcaacctc attccgagca781 ccagggtgtg gtttactgca gggcggaggc cgggggcaga tctcagatct ccgtcaagta841 ccagctgctc tacgtggcgg ttcccagtgg ccctccctca acaaccatct tggcttcttc901 aaacaaagtg aaaagtgggg acgacatcag tgtgctctgc actgtcctgg gggagcccga961 tgtggaggtg gagttcacct ggatcttccc agggcagaag gatgaaaggc ctgtgacgat
1021 ccaagacact tggaggttga tccacagagg actgggacac accacgagaa tctcccagag1081 tgtcattaca gtggaagact tcgagacgat tgatgcagga tattacattt gcactgctca1141 gaatcttcaa ggacagacca cagtagctac cactgttgag ttttcctgac ttggaaaagg1201 aaatgtaatg aacttatgga aagcccattt gtgtacacag tcagctttgg ggttcctttt1261 attagtgctt tgccagaggc tgatgtcaag caccacaccc caaccccagc gtctcgtgag1321 tccgacccag acatccaaac taaaaggaag tcatccagtc tattcacaga agtgttaact1381 tttctaacag aaagcatgat tttgattgct tacctacata cgtgttccta gtttttatac1441 atgtgtaaac aattttatat aatcaatcat ttctattaaa tgagcacgtt tttgtaaaaa1501 at<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>105<211>1496<212>DNA<213>人類(Homo sapiens)<400>1051 cgcactccct gctgggtgag cagcactgta aagatgaagc tggctaactg gtactggctg61 agctcagctg ttcttgccac ttacggtttt ttggttgtgg caaacaatga aacagaggaa121 attaaagatg aaagagcaaa ggatgtctgc ccagtgagac tagaaagcag agggaaatgc181 gaagaggcag gggagtgccc ctactaggta agcctgcccc ccttgactat tcagctcccg241 aagcaattca gcaggatcga ggaggtgttc aaagaagtcc aaaacctcaa ggaaatcgta301 aatagtctaa agaaatcttg ccaagactgc aagctgcagg ctgatgacaa cggagaccca361 ggcagaaacg gactgttgtt acccagtaca ggagccccgg gagaggttgg tgataacaga421 gttagagaat tagagagtga ggttaacaag ctgtcctctg agctaaagaa tgccaaagag481 gagatcaatg tacttcatgg tcgcctggag aagctgaatc ttgtaaatat gaacaacata541 gaaaattatg ttgacagcaa agtggcaaat ctaacatttg ttgtcaatag tttggatggc601 aaatgttcaa agtgtcccag ccaagaacaa atacagtcac gtccagttca acatctaata661 tataaagatt gctctgacta ctacgcaata ggcaaaagaa gcagtgagac ctacagagtt721 acacctgatc ccaaaaatag tagctttgaa gtttactgtg acatggagac catgggggga781 ggctggacag tgctgcaggc acgtctcgat gggagcacca acttcaccag aacatggcaa841 gactacaaag caggctttgg aaacctcaga agggaatttt ggctggggaa cgataaaatt901 catcttctga ccaagagtaa ggaaatgatt ctgagaatag atcttgaaga ctttaatggt961 gtcgaactat atgccttgta tgatcagttt tatgtggcta atgagtttct caaatatcgt1021 ttacacgttg gtaactataa tggcacagct ggagatgcat tacgtttcaa caaacattac1081 aaccacgatc tgaagttttt caccactcca gataaagaca atgatcgata tccttctggg1141 aactgtgggc tgtactacag ttcaggctgg tggtttgatg catgtctttc tgcaaactta1201 aatggcaaat attatcacca aaaatacaga ggtgtccgta atgggatttt ctggggtacc1261 tggcctggtg taagtgaggc acaccctggt ggctacaagt cctccttcaa agaggctaag1321 atgatgatca gacccaagca ctttaagcca taaatcactc tgttcattcc tccaggtatt1381 cgttatctaa tagggcaatt aattccttca gcactttaga atatgccttg tttcatattt1441 ttcatagcta aaaaatgttt gacatccttt gagatatttt attactaaaa tctgcc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>106
<211>1641<212>DNA<213>人類(Homo sapiens)<400>1061 gaattcgggg gctgcggaga gggtgcttaa ctgaggggca tgatggggga ggcggccgtg61 ccgcggggct tgtcgttgcg cgaggacagc ttcacgcgct tctcgtcgca gaacaatgtg121 tacgggctgg caggcggcgc cggcgggcgc ggggagctgc tggccgccac ccttaaaggc181 aaggtgctcg gcttccgtta ccaagacctc cgacagaaaa tccggccagt ggccaaggag241 ctgcagttca actacattcc cgtggatgcg gagattgtct ccatcgacac tttcaacaag301 tcacccccca agcggggtct ggttgtgggg atcacgttca tcaaggattc aggggacaag361 ggcagcccct tcctgaacat ttactgcgac tacgagaccg gctctgtgta caaccttgtc421 tctattgccc agagctgcct gaacctggag ctccagttca ctccgttcca gctgtgccat481 gcggaggtcc aggtcgggga tcaacttgag actgtgtttc tcttgagtgg gaacgacccg541 gccattcatc tctacaagga gaacgagggc ctgcatcagt ttgaggaaca gcccgtggaa601 aacctcttcc cagagctgac gaacctgacc agtagcgtcc tctggctgga cgtccacaac661 ttccccggca cgtcccggcg cctctcagct ctgggctgtc agagtggtta tgtccgtgtc721 gcccacgtgg accagcggag tcgagaggtt ctgcagatgt ggtcggtcct gcaggacggt781 cccatctccc gagtgattgt gttcagcctc tcggccgcca aggagaccaa ggacaggcca841 ctacaagatg agtacagcgt gctcgtggcc agcatgttgg agccagcagt ggtgtatcgg901 gacctgctga accggggtct tgaagaccag cttctcctgc ccggcagtga ccagtttgac961 agcgtcctct gcagcctggt caccgatgtg gatttggatg ggcggccaga agtcctggtg1021 gccacctatg gacaggaact gctgtgttat aagtaccggg gcccagagtc ggggcttcct1081 gaggcccagc acgggttcca tctgctgtgg cagcggagct tctccagtcc cctgctggcc1141 atggctcacg tggacctgac cggggatggg ctgcaggagc ttgccgtggt ctccctgaag1201 ggcgtgcaca tcctgcagca cagcctgatt caggcctcag agctggtctt gacccggctt1261 cgaacatcaa gtggagcaga ggagacgtcg gcctacaggg gttggaggac ggggcaggtg1321 cagggcctgc tgagaatgca gcctcttaag cacccatgca cccactcttc ccagacctgg1381 ggcgactcat ggcgtgctca cctccagccg ctggtggggg gtgtcctgaa ggacaggatg1441 ctctccccag acctccccag ggtggtgaag ctgtgccctg gggccccagc taacccactc1501 ctctctctgt acgtcaatgt ccctatttga aagcagggat gatcccattc caccctgtcc1561 actctggatg agaattggcc acctgatggt tatttatacg tccagaagaa catccccaaa1621 aaaaaaaaaa aaaccgaatt c<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>106<211>1641<212>DNA<213>人類(Homo sapiens)<400>1061 gaattcgggg gctgcggaga gggtgcttaa ctgaggggca tgatggggga ggcggccgtg61 ccgcggggct tgtcgttgcg cgaggacagc ttcacgcgct tctcgtcgca gaacaatgtg121 tacgggctgg caggcggcgc cggcgggcgc ggggagctgc tggccgccac ccttaaaggc181 aaggtgctcg gcttccgtta ccaagacctc cgacagaaaa tccggccagt ggccaaggag241 ctgcagttca actacattcc cgtggatgcg gagattgtct ccatcgacac tttcaacaag301 tcacccccca agcggggtct ggttgtgggg atcacgttca tcaaggattc aggggacaag361 ggcagcccct tcctgaacat ttactgcgac tacgagaccg gctctgtgta caaccttgtc
421 tctattgccc agagctgcct gaacctggag ctccagttca ctccgttcca gctgtgccat481 gcggaggtcc aggtcgggga tcaacttgag actgtgtttc tcttgagtgg gaacgacccg541 gccattcatc tctacaagga gaacgagggc ctgcatcagt ttgaggaaca gcccgtggaa601 aacctcttcc cagagctgac gaacctgacc agtagcgtcc tctggctgga cgtccacaac661 ttccccggca cgtcccggcg cctctcagct ctgggctgtc agagtggtta tgtccgtgtc721 gcccacgtgg accagcggag tcgagaggtt ctgcagatgt ggtcggtcct gcaggacggt781 cccatctccc gagtgattgt gttcagcctc tcggccgcca aggagaccaa ggacaggcca841 ctacaagatg agtacagcgt gctcgtggcc agcatgttgg agccagcagt ggtgtatcgg901 gacctgctga accggggtct tgaagaccag cttctcctgc ccggcagtga ccagtttgac961 agcgtcctct gcagcctggt caccgatgtg gatttggatg ggcggccaga agtcctggtg1021 gccacctatg gacaggaact gctgtgttat aagtaccggg gcccagagtc ggggcttcct1081 gaggcccagc acgggttcca tctgctgtgg cagcggagct tctccagtcc cctgctggcc1141 atggctcacg tggacctgac cggggatggg ctgcaggagc ttgccgtggt ctccctgaag1201 ggcgtgcaca tcctgcagca cagcctgatt caggcctcag agctggtctt gacccggctt1261 cgaacatcaa gtggagcaga ggagacgtcg gcctacaggg gttggaggac ggggcaggtg1321 cagggcctgc tgagaatgca gcctcttaag cacccatgca cccactcttc ccagacctgg1381 ggcgactcat ggcgtgctca cctccagccg ctggtggggg gtgtcctgaa ggacaggatg1441 ctctccccag acctccccag ggtggtgaag ctgtgccctg gggccccagc taacccactc1501 ctctctctgt acgtcaatgt ccctatttga aagcagggat gatcccattc caccctgtcc1561 actctggatg agaattggcc acctgatggt tatttatacg tccagaagaa catccccaaa1621 aaaaaaaaaa aaaccgaatt c<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>107<211>2732<212>DNA<213>人類(Homo sapiens)<400>1071 gtctttattt cagtcccgga tccgcgggcg caggcccagc tcaggccccc agggatggac61 gtcgtggacc ctgacatttt caatagagac ccccgggacc actatgacct gctacagcgg121 ctgggtggcg gcacgtatgg ggaagtcttt aaggctcgag acaaggtgtc aggggacctg181 gtggcactga agatggtgaa gatggagcct gatgatgatg tctccaccct tcagaaggaa241 atcctcatat tgaaaacttg ccggcacgcc aacatcgtgg cctaccatgg gagttatctc301 tggttgcaga aactctggat ctgcatggaa ttctgtgggg ctggttctct ccaggacatc361 taccaagtga caggctccct gtcagagctc cagattagct atgtctgccg ggaagtgctc421 cagggactgg cctatttgca ctcacagaag aagatacaca gggacatcaa gggagctaac481 atcctcatca atgatgctgg ggaggtcaga ttggctgact ttggcatctc ggcccagatt541 ggggctacac tggccagacg cctctctttc attgggacac cctactggat ggctccggaa601 gtggcagctg tggccctgaa gggaggatac aatgagctgt gtgacatctg gtccctgggc661 atcacggcca tcgaactggc cgagctacag cgagcgctct ttgatgtgca ccctctcaga721 gttctcttcc tcatgaccaa gagtggctac cagcctcccc gactgaagga aaaaggcaaa781 tggtcggctg ccttccacaa cttcatcaaa gtcactctga ctaagagtcc caagaaacga841 cccagcgcca ccaagatgct cagtcatcaa ctggtatccc agcctgggct gaatcgaggc901 ctgatcctgg atcttcttga caaactgaag aatcccggga aaggaccctc cattggggac961 attgaggatg aggagcccga gctaccccct gctatccctc ggcggatcag atccacccac1021 cgctccagct ctctggggat cccagatgca gactgctgtc ggcggcacat ggagttcagg
1081 aagctccgag gaatggagac cagaccccca gccaacaccg ctcgcctaca gcctcctcga1141 gacctcagga gcagcagccc caggaagcaa ctgtcagagt cgtctgacga tgactatgac1201 gacgtggaca tccccacccc tgcagaggac acacctcctc cacttccccc caagcccaag1261 ttccgttctc catcagacga gggtcctggg agcatggggg atgatgggca gctgagcccg1321 ggggtgctgg tccggtgtgc cagtgggccc ccaccaaaca gcccccgtcc tgggcctccc1381 ccatccacca gcagccccca cctcaccgcc cattcagaac cctcactctg gaacccaccc1441 tcccgggagc ttgacaagcc cccacttctg ccccccaaga aggaaaagat gaagagaaag1501 ggatgtgccc ttctcgtaaa gttgttcaat ggctgccccc tccggatcca cagcacggcc1561 gcctggacac atccctccac caaggaccag cacctgctcc tgggggcaga ggaaggcatc1621 ttcatcctga accggaatga ccaggaggcc acgctggaaa tgctctttcc tagccggact1681 acgtgggtgt actccatcaa caacgttctc atgtctctct caggaaagac cccccacctg1741 tattctcata gcatccttgg cctgctggaa cggaaagaga ccagagcagg aaaccccatc1801 gctcacatta gcccccaccg cctactggca aggaagaaca tggtttccac caagatccag1861 gacaccaaag gctgccgggc gtgctgtgtg gcggagggtg cgagctctgg gggcccgttc1921 ctgtgcggtg cattggagac gtccgttgtc ctgcttcagt ggtaccagcc catgaacaaa1981 ttcctgcttg tccggcaggt gctgttccca ctgccgacgc ctctgtccgt gttcgcgctg2041 ctgaccgggc caggctctga gctgcccgct gtgtgcatcg gcgtgagccc cgggcggccg2101 gggaagtcgg tgctcttcca cacggtgcgc tttggcgcgc tctcttgctg gctgggcgag2161 atgagcaccg agcagagggg acccgtgcag gtgacccagg tagaggaaga tatggtgatg2221 gtgttgatgg atggctctgt gaagctggtg accccggagg ggtccccagt ccggggactt2281 cgcacacctg agatccccat gaccgaagcg gtggaggccg tggctatggt tggaggtcag2341 cttcaggcct tctggaagca tggagtgcag gtgtgggctc taggctcgga tcagctgcta2401 caggagctga gagaccctac cctcactttc cgtctgcttg gctcccccag gctggagtgc2461 agtggcacga tctcgcctca ctgcaacctc ctcctcccag gttcaagcaa ttctcctgcc2521 tcagcctccc gagtagctgg gattacaggc ctgtagtggt ggagacacgc ccagtggatg2581 atcctactgc tcccagcaac ctctacatcc aggaatgagt ccctaggggg gtgtcaggaa2641 ctagtccttg caccccctcc cccatagaca cactagtggt catggcatgt cctcatctcc2701 caataaacat gactttagcc tctgcaaaaa aa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>108<211>4973<212>DNA<213>人類(Homo sapiens)<400>1081 cagctatcaa aaaggccata aggattttgt ccccaaattt cacatgagct accttgcttc61 aaactactga gatgaagggg gcaagattat ttgtccttct ttctagttta tggagtgggg121 gcattgggct taacaacagt aagcattctt ggactatacc tgaggatggg aactctcaga181 agactatgcc ttctgcttca gttcctccaa ataaaataca aagtttgcaa atactgccaa241 ccactcgggt catgtcggcg gagatagcta caactccaga ggcaagaact tctgaagaca301 gtcttcttaa atcaacactg cctccctcag aaacaagtgc acctgctgag ggtgtgagaa361 atcaaactct cacatccaca gagaaagcag aaggagtggt caagttacag aatcttaccc421 tcccaaccaa cgctagcatc aagttcaatc ctggagcaga atcagtggtc ctttccaatt481 ctacactgaa atttcttcag agctttgcca gaaagtcaaa tgaacaagca acttctctaa541 acacagttgg aggcactgga ggcattggag gcgttggagg cactggaggc gtgggaaatc601 gagccccacg ggaaacatac ctcagccggg gtgacagcag ttccagccaa agaactgact
661 accaaaaatc aaatttcgaa acaactagag gaaagaattg gtgtgcttat gtacatacca721 ggttatctcc cacagtgata ttggacaacc aggtcactta tgtcccaggt gggaaaggac781 cttgtggctg gaccggtgga tcctgtcctc agagatctca gaagatatcc aatcctgtct841 ataggatgca acataaaatt gtcacctcat tggattggag gtgctgtcct ggatacagtg901 ggccgaaatg tcaactaaga gcccaggaac agcaaagttt gatacacacc aaccaggctg961 aaagtcatac agctgttggc agaggagtag ctgagcagca gcagcagcaa ggctgtggtg1021 acccagaagt gatgcaaaaa atgactgatc aggtgaacta ccaggcaatg aaactgactc1081 ttctgcagaa gaagattgac aatatttctt tgactgtgaa tgatgtaagg aacacttact1141 cctccctaga aggaaaagtc agcgaagata aaagcagaga atttcaatct cttctaaaag1201 gtctaaaatc caaaagcatt aatgtactga taagagacat agtaagagaa caatttaaaa1261 tttttcaaaa tgacatgcaa gagactgtag cacagctctt caagactgta tcaagtctat1321 cagaggacct cgaaagcacc aggcaaataa ttcaaaaagt taatgaatct gtggtttcaa1381 tagcagccca gcaaaagttt gttttggtgc aagagaatcg gcccactttg actgatatag1441 tggaactaag gaatcacatt gtgaatgtaa ggcaagaaat gactcttaca tgtgagaagc1501 ctattaaaga actagaagta aagcagactc atttagaagg tgctctagaa caggaacact1561 caagaagcat tctgtattat gaatccctca ataaaactct ttctaaattg aaggaagtac1621 atgagcagct tttatcaact gaacaggtat cagaccagaa gaatgctcca gctgctgagt1681 cagttagcaa taatgtcact gagtacatgt ctactttaca tgaaaatata aagaagcaga1741 gtttgatgat gctgcaaatg tttgaagatt tgcacattca agaaagcaag attaacaatc1801 tcaccgtctc tttggagatg gagaaagagt ctctcagagg tgaatgtgaa gacatgttat1861 ccaaatgcag aaatgatttt aaatttcaac ttaaggacac agaagagaat ttacatgtgt1921 taaatcaaac attggctgaa gttctctttc caatggacaa taagatggac aaaatgagtg1981 agcaactaaa tgatttgact tatgatatgg agatccttca acccttgctt gagcagggag2041 catcactcag acagacaatg acatatgaac aaccaaagga agcaatagtg ataaggaaaa2101 agatagaaaa tctgactagt gctgtcaata gtctaaattt tattatcaaa gaacttacaa2161 aaagacacaa cttacttaga aatgaagtac agggtcgtga tgatgcctta gaaagacgta2221 tcaatgaata tgccttagaa atggaagatg gcctcaataa gacaatgact attataaata2281 atgctattga tttcattcaa gataactatg ccctaaaaga gactttaagt actattaagg2341 ataatagtga gatccatcat aaatgtacct ccgatatgga aactattttg acatttattc2401 ctcagttcca ccgtctgaat gattctattc agactttggt caatgacaat cagagatata2461 actttgtttt gcaagtcgcc aagacccttg caggtattcc cagagatgag aaactaaatc2521 agtccaactt ccaaaagatg tatcaaatgt tcaatgaaac cacttcccaa gtgagaaaat2581 accagcaaaa tatgagtcat ttggaagaaa aactactctt aactaccaag atttccaaaa2641 attttgagac tcggttgcaa gacattgagt ctaaagttac ccagacgctc ataccttatt2701 atatttcagt taaaaaaggc agtgtagtta caaatgagag agatcaggct cttcaactgc2761 aagtattaaa ttccagattt aaggcgttgg aagcaaaatc tatccatctt tcaattaact2821 tcttttcgct taacaaaact ctccacgaag ttttaacaat gtgtcacaat gcttctacaa2881 gtgtgtcaga actgaatgct accatcccta agtggataaa acattccctg ccagatattc2941 aacttcttca gaaaggtcta acagaatttg tggaaccaat aattcaaata aaaactcaag3001 ctgccctatc taatttaact tgttgtatag atcgatcgtt gcctggtagt ctggcaaatg3061 ttgtcaagtc tcagaagcaa gtaaaatcat tgccaaagaa aattaacgca cttaagaaac3121 caacggtaaa tcttaccaca gtcctgatag gccggactca aagaaacacg gacaacataa3181 tatatcctga ggagtattca agctgtagtc ggcatccgtg ccaaaatggg ggcacgtgca3241 taaatggaag aactagcttt acctgtgcct gcagacatcc ttttactggt gacaactgca3301 ctatcaagct tgtggaagaa aatgctttag ctccagattt ttccaaagga tcttacagat3361 atgcacccat ggtggcattt tttgcatctc atacgtatgg aatgactata cctggtccta3421 tcctgtttaa taacttggat gtcaattatg gagcttcata taccccaaga actggaaaat3481 ttagaattcc gtatcttgga gtatatgttt tcaagtacac catcgagtca tttagtgctc
3541 atatttctgg atttttagtg gttgatggaa tagacaagct tgcatttgag tctgaaaata3601 ttaacagtga aatacactgt gatagggttt taactgggga tgccttatta gaattaaatt3661 atgggcagga agtctggtta cgacttgcaa aaggaacaat tccagccaag tttccccctg3721 ttactacatt tagtggctat ttattatatc gtacataagt tagtatgaaa aacagactat3781 cacctttatt gagaaacagc cagtgttttc atttatcttt gcttgcacat ctgctctgtt3841 ttggtttttc tacaggaaat gaaaatcaac ttgttttttt aatatgagta aacttgtatg3901 tctattttat aaaattattt gaatattgtt taatgtctga atatgaaaga gttcttgatc3961 ctaaagaaat ttagtggcac agaaaacaaa gtgaatttgt tagcataatt attcctattc4021 ttatttcttc attttaagtc attgcaatgg aaagtaatat tataaaatgg taattacaac4081 atattatcag tcacagtttt ctttccaatt aaacacttaa cttttgttat tccctgtata4141 taaatatata acacacattt tctagattca caaatttaaa taaattactc aaaaaatgaa4201 aattgatttt gtaaactttt atttttactc tttacgttga gttgatcaat tttccatact4261 aagattttca ttcagaatca aaattaagaa agttggactg aaaatatgaa aaatgcttaa4321 ctattgttct cttcctataa ttctctaatt ataacatagt aatttacatg tagttggaca4381 tgtacactca agtctaagaa tatatgagtg gatcatttac cgccccccgc cccacaacat4441 ctataagggg caaaaagtct ttttctaata agtattcttc tatggtagta cctacagatc4501 tgcccttctt cttctaaagg gtaagtcata atctgtgtaa tactacaatt tatgggatgc4561 tcactatgcc ctgtttctct tctaaacaat ttacatgtaa tgtctcattc ctcacaataa4621 cccttgtaaa gtgggcatga ttaccatgat ttttatagtt gaagaaccta agacacagag4681 accaaggccc atgagctcat agggctgagg caggatttgg aatcaggcca tgtcttctcc4741 agagcccaca tccatccttt ctctatattg cctcccacag atgtgctaaa atttatttaa4801 ctaatccttt atcctctatt tgtgttgtct cccatttttt attattacaa tattactgtg4861 gtgaacatgc ttaaaaatac attccttgga tatctgacaa cgtgtttctg aaaaacagat4921 tttcataagt aataataaaa ataataataa aaaagttttg gtatggtaaa aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>109<211>3949<212>DNA<213>人類(Homo sapiens)<400>1091 aggagccgac gggcgctcgc aggctcagcg cgcgctgccc gcggcaggac ccggccgcct61 ccgccgccgc cgccgcccct aagcctcccg aagccatggc cgggctcggc caccccgccg121 ccttcggccg ggccacccac gccgtggtgc gggcgctacc cgagtcgctc ggccagcacg181 cgctgagaag cgccaagggc gaggaggtgg acgtcgcccg cgcggaaggg cagcaccagc241 tctacgtggg cgtgctgggc agcaagctgg ggctgcaggt ggtggagctg ccggccgacg301 agagccttcc ggactgcgtc ttcgtggagg acgtggccgt ggtgtgcgag gagacggccc361 tcatcacccg acccggggcg ccgagccgga ggaaggaggt tgacatgatg aaagaagcat421 tagaaaaact tcagctcaat atagtagaga tgaaagatga aaatgcaact ttagatggcg481 gagatgtttt attcacaggc agagaatttt ttgtgggcct ttccaaaagg acaaatcaac541 gaggtgctga aatcttggct gatactttta aggactatgc agtctccaca gtgccagtgg601 cagatgggtt gcatttgaag agtttctgca gcatggctgg gcctaacctg atcgcaattg661 ggtctagtga atctgcacag aaggccctta agatcatgca acagatgagt gaccaccgct721 acgacaaact cactgtgcct gatgacatag cagcaaactg tatatatcta aatatcccca781 acaaagggca cgtcttgctg caccgaaccc cggaagagta tccagaaagt gcaaaggttt841 atgagaaact gaaggactat atgctgatcc ccgtgagcat gtctgaactg gaaaaggtgg
901 atgggctgct cacctgctgc tcagttttaa ttaacaagaa agtagactcc tgagctgcag961 agtccccccc ggtagccggc aagaccgcac aggcaaggcc gatgactctg tgcccactcc1021 tgttgttttc cttgacaatc tactgtgcca ctgtgctact aactcttgtt tacaaaattt1081 gattctaagt tgaattgctt cattcaacac ccccaccctc cctcccctcg aggtggtacc1141 taagctgtgg atttgctaaa tgaattaagc aacctagaag atacagagct aatgaattat1201 caaaatgtga ttaatcccag taaggaaaca ctcatttagt gtctgtattt ttggtgtgaa1261 aattatttag ttgccagtat attctgaaga atgtcttctt gatcagtcag ataagcttgc1321 tttttttttt tttttttttc atgaatcatg tttggttcct gtgaaagtcc ctggtccagg1381 gatcctcctc ctttctcttt tacttctgaa ttctgaaatt cagttagtta cttttgcctt1441 tcgctcttct atcacagcca ccttgacctt gggtaaaacc caaggtcttt ccttctggct1501 accttcctgc aggtccaccc tgtctgccat tggtctcctc tgcctctgac tacatctgcc1561 accaacaacc ctcccctcac ccctgccagg ggcagacagg cttctcagca gaactgtgac1621 tgaaatcaga gctgctgtct ggggcagtgt taactacaca gaggcacatc ctgacagggt1681 ttgccccaga gatctaaatt ccagaaggag ggcaccacac ctaggaaggt aaatccagta1741 tcagaaggtt gctaaaagat taaagatcaa gaagcttgga aacatcccat gggtacaatg1801 tcttagaaag tctttaagtc acataccatg aatttttgct tcattactga ccatatatga1861 ccttggagga actctttttt ttttttcctt ctactcattt ctgtttccac ctaccctgac1921 tcaccgtatt tccagtcttc tacccctgca gttatcctag tccagcaaag tcatttcttt1981 caaaagagac atcatgtctg aaaataatta ctggtagtct aatatgagcc agagtaaaca2041 gctcctcatg gtcaatgaac atgttcagga agcgatcacc ttgatgcttg aacccaaccc2101 cagacagtgg acaattctac tttgaaatat ccgtgaatat ttactgtggg atccaattta2161 aacttctttc ttctctagcc tttaaattac acaactttga actgacacgg atctcttaca2221 aagaacaatg cggcactgaa ggaagagatg attcctttac tcaaacctgc aggaatcagc2281 ctattaacag gcaggggaaa cggtactttc caatgaatgg taactgatcc aggcacatta2341 tcacacttcc tagtcatctc cacctttcct gtattgcctg tggcttgttg tttaagatta2401 agaatcaaag agattaagaa gtatcacttc aagtcttgct ctgctcactt ctatgtttgc2461 agtcaaatta ttccttatgt tggtgaccta aagagaatta ctttcattca tttcatttcc2521 cccgtagcag atggaagtga gaaacctctg agaaaatgaa aacatcctta accactatct2581 ttccctttta tttgattatt ttatgtcaga aatttgcaaa agtttttttc tcctccttct2641 cttccttgtt gcttaacttt ttaattcatg ccatatgcag atatccaatt atgtgcatcc2701 tgtgaataaa ccacgtcttg gtcactgtca tattttgaac catctcatca gagatgaata2761 atatcttttt accagagaga gaacgaatgt tagccacatg cccaagttaa caaagaaaaa2821 atgttctcaa ggttgtcctt ttgggttaaa tctggccctt ccttggcaaa agcaaaaatt2881 ctccctgtga gagctcaaca tctcaaatac aaccacagga aaaatggccc aatctgccag2941 tttaggctta ccagcatata atttttaata tctttacttc tatcatccca aatcaaagaa3001 ctcttctcta ttatgtttaa tcaattgcaa gcaaatagat ttttctttgt aacaatttgt3061 tctgcagaag gctgtttttc acttttcctt tcttttgctt ctttctgtct ttccttctct3121 tttgtctgga gaaatcactt agactctgtg tgcctcttct acattgcatt ctgctctgct3181 atgttacctg ctaggctggc ttctttggac tccctatatg attgatgatg tgaaaaccta3241 aattacttgc agcatagtat tacttctttg atgttctcat tagcataatg ttatttttga3301 aaaggaaaga tactatcaca taagttttcc tcatctgttg tgatatacac caatggataa3361 actaacggaa actgcttttt gacattaaaa gacaggagaa attatattta actaagtaaa3421 agttaagtca gaattacttg ggtgatgtga ttcaatttag ttaaaggatg atatagagaa3481 aatacattat ttagcattat ttcttcagct ataatgaatt gctatagaaa tcaggcagat3541 ctttctaatg tgtattgatt ggtcttttca gctactctga acagattact aaggccatct3601 cctcatctct aagggagaaa aatagtctgt agatgaataa tgtaaggtaa agagttgcat3661 gtcagtcttt gtaattattt acactttaac tttctccaga actcagacat gatttcaaca3721 tggtgttaga tttgtgcatt ttattttcct gaccacctca ttccagccaa tgtatggtta
3781 tccactctgt gtgccaaaac caatcatgcc tttcacggcc ctttagttca gagaagttct3841 gcactgattt ttagtctctt gatgtctcaa tcttacatgt ataccaatca caatggaata3901 aagtgttgag ttgtactgtg aaaaaaaaaa aaaaaaaaaa aaaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>110<211>1351<212>DNA<213>人類(Homo sapiens)<400>1101 ccgcttagac aatgccccgg agccgccaga ccgtcgcgcc cctgccccat cgtagtatat61 gagctcgcct acacaaggac ccccgctaaa agccagagct cccagtcccc gaggcttgaa121 gacggggact cccttctcca ccaactctgt cctcgggggg tggggcccca gccgagatca181 cagcgcgaca ggagtggggg tggccgctgg agacaggtga agaaacaaga aaactaagaa241 atccgagcgg ttggaggggg agtctgtgtg gatgggatgg ggacgccggg ggaggggctg301 ggccgctgct cccatgccct gatccgggga gtcccagaga gcctggcgtc gggggaaggt361 gcgggggctg gccttcccgc tctggatctg gccaaagctc aaagggagca cggggtgctg421 ggaggtaaac tgaggcaacg actggggcta cagctgctag aactgccacc tgaggagtca481 ttgccgctgg gaccgctgct tggcgacacg gccgtgatcc aaggggacac ggccctaatc541 acgcggccct ggagccccgc tcgtaggcca gaggtcgatg gagtccgcaa agccctgcaa601 gacctggggc tccgaattgt ggaaatagga gacgagaacg cgacgctgga tggcactgac661 gttctcttca ccggccggga gtttttcgta ggcctctcca aatggaccaa tcaccgagga721 gctgagatcg tggcggacac gttccgggac ttcgccgtct ccactgtgcc agtctcgggt781 ccctcccacc tgcgcggtct ctgcggcatg gggggacctc gcactgttgt ggcaggcagc841 agcgacgctg ccgaaaaggc tgtccgggca atggcagtgc tgacagatca cccatatgcc901 tccctgaccc tcccagatga cgcagctgct gactgcctct ttcttcgtcc tgggttgcct961 ggtgtgcccc ctttcctcct gcaccgtgga ggtggggatc tgcccaacag ccaggaggca1021 ctgcagaagc tctctgatgt caccctggta cctgtgtcct gctcagaact ggagaaggct1081 ggcgccgggc tcagctccct ctgcttggtg ctcagcacac gcccccacag ctgagggcct1141 ggccttgggg tactgctggc caggggtagg atagtatagg aagtagaagg ggaaggaggg1201 ttagatagag aatgctgaat aggcagtagt tgggagagag cctcaatatt gggggagggg1261 agagtgtagg gaaaaggatc cactgggtga atcctccctc tcagaaccaa taaaatagaa1321 ttgacctttt aaaaaaaaaa aaaaaaaaaa a<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>111<211>7062<212>DNA<213>人類(Homo sapiens)<400>1111 gtgaggccct gccgggtcgg gctgcgggcg gccgggcgcg ggcggcggga cagacgggcg61 cacgcgagga ctgacggacg gacgcaccga gggcggcggg cacgcacggc ccgggccggc121 gctccaaggc ccgcccggga gggccggggc cgcgctcaga attttgattt ggctgctggg181 ctgctacctt gaaatccaag ccctaaaaat gccagcttct ttggacttag aagatgacct
241 ggataaatga taaaaattaa gaaagagatt ttgaagtttt cttattgtcc tcttggcata301 tgcttctgga ataatattca ccatggtttt ggatgacctt ccaaacttag aagacatcta361 tacttccttg tgttcatcaa caatggaaga ctcagagatg gattttgact ctggactaga421 agatgatgac acaaaaagtg atagtatttt ggaggattcc acaatttttg tggccttcaa481 aggaaatata gatgataaag acttcaaatg gaaattagat gcaatattga aaaacgtgcc541 caatttgtta cacatggagt ccagcaagct aaaagtacag aaggtggagc cctggaacag601 cgtgcgtgtg acattcaaca tcccccggga agcagcggag cggctacgga tccttgctca661 gagcaacaac cagcagcttc gggatttagg gattctctcc gttcagattg aaggggaagg721 tgctattaac ctggctttgg ctcagaaccg aagccaagat gtgagaatga atggacccat781 gggagctgga aattcagtta ggatggaggc gggatttcct atggcaagtg gtccaggaat841 aataaggatg aacaaccctg ccactgttat gatacccccg ggtggaaatg tgtcatcttc901 catgatggca ccaggcccca atccagagct gcagcccagg actcctcgcc ctgcttctca961 gtcagatgca atggatccac tcctctctgg gctccatata cagcagcaaa gtcatccctc1021 aggatcttta gctcccccac atcacccaat gcagcctgtc tctgtgaaca gacaaatgaa1081 cccagctaat tttccccagc tgcagcagca gcagcaacaa caacaacagc agcagcagca1141 gcagcagcag caacaacagc aacagcagca acaacagttg caggcaagac ccccacagca1201 acatcagcag caacagccac agggaattcg accccagttt actgccccaa ctcaggtgcc1261 tgttcctcca ggctggaacc agctgccttc tggagccctt caacctcctc cagcccaggg1321 ttctctgggc acaatgactg caaaccaagg gtggaagaag gctcccttgc ccggcccaat1381 gcaacagcaa ctccaggcaa gaccatcctt agccacggta cagacgcctt cccaccctcc1441 ccctccatat ccctttggca gccagcaagc ctcacaagcc cacacaaact ttcctcagat1501 gagcaaccca ggccagttca cagctcctca gatgaagagt ttgcagggag ggccctctag1561 ggtcccaact cccttgcagc agccccacct caccaacaag tctcctgcct cctcaccctc1621 ctccttccag cagggatccc ctgcatcctc cccaacggtt aaccaaactc agcagcagat1681 gggaccaagg ccacctcaaa ataacccact tccccaggga tttcagcagc ctgtcagctc1741 tccgggtcgg aatcctatgg ttcaacaggg aaatgtgcca cctaacttca tggtgatgca1801 gcagcaacca ccaaaccagg ggccacagag tttacatcca ggcctaggag gaatgcctaa1861 acgcctccca cctggcttct cagcaggaca ggccaatccg aactttatgc aaggtcaggt1921 gccttcgacc acagcaacca cccctgggaa ttcaggagcc cctcagctgc aagcaaatca1981 aaatgtccag catgcaggtg gtcaaggagc tggtcctcct caaaaccaga tgcaggtgtc2041 ccacgggccg ccaaatatga tgcagcccag cctcatggga attcatggca acatgaacaa2101 tcagcaggct ggtacttctg gggttcctca agtgaacctc agcaacatgc aaggccagcc2161 ccagcagggc ccaccatctc agctgatggg catgcaccag caaatcgtgc cctcccaggg2221 ccagatggtc cagcaacaag gaaccttgaa ccctcagaac cctatgatcc tttcaagggc2281 ccagcttatg ccacagggcc agatgatggt gaaccccccg agccaaaatc ttgggccctc2341 gccccaaagg atgaccccac ccaagcagat gctttcccag cagggcccac aaatgatggc2401 gccacataac cagatgatgg ggcctcaggg gcaggttttg ctccaacaga acccaatgat2461 agagcagatt atgaccaatc aaatgcaggg gaataagcag cagtttaaca ctcagaacca2521 gtccaatgtc atgccgggac cagcccagat aatgagggga ccaactccga acatgcaagg2581 aaatatggtg cagtttacgg gacagatgtc aggacagatg ctgccccagc aagggcctgt2641 gaacaacagt ccatctcagg ttatgggcat tcagggacag gtcctgcggc caccagggcc2701 cagcccacac atggcccagc agcatggtga tcctgctact acagcaaata acgatgtcag2761 tttatctcag atgatgcctg atgttagcat tcaacaaacc aacatggtcc cccctcatgt2821 gcaggccatg cagggaaaca gtgcctcggg aaaccacttc tcaggccatg ggatgtcttt2881 caatgcacct ttcagtggag ctcccaatgg aaatcagatg tcctgtggtc aaaatccagg2941 cttcccagtc aataaggatg tcacgctaac gagcccattg ttggtcaact tattgcagag3001 tgacatatct gcaggccatt ttggggtaaa caataagcaa aataatacca acgcaaataa3061 accgaagaag aagaaacccc ctcggaagaa gaaaaatagt cagcaagatc taaacacccc
3121 agatactcgc ccagctggtc tggaagaggc tgatcagcca ccgttgcctg gagaacaagg3181 aattaacttg gataactcag gccctaaact gccagaattt tcaaaccggc caccaggtta3241 tccttctcaa ccagttgaac agaggccact tcagcagatg cctcctcaac tcatgcagca3301 tgtggcaccc ccaccacagc caccacagca gcagccacag ccacaactgc ctcagcagca3361 gcagccacca cctcccagtc agccacagtc tcagcagcag cagcagcagc agcaacaaat3421 gatgatgatg ctcatgatgc agcaggatcc caaatcagtt aggcttccag tctctcaaaa3481 tgtccatcct ccaaggggcc ccctgaaccc cgactcccag agaatgccca tgcaacagag3541 tggcagtgtg cctgtcatgg tcagtctgca aggacctgcc tccgtgccac catcacctga3601 taaacaaaga atgccaatgc ctgtgaatac tcccttggga agcaattcaa ggaaaatggt3661 ctatcaggag agcccgcaga atccttccag ctcgccactg gcggagatgg cctcactccc3721 tgaagcaagt ggcagtgaag caccatctgt cccaggaggc ccaaacaaca tgccttcaca3781 tgtagtactt ccccagaatc agttaatgat gacagggcca aaacctggac catcgcccct3841 ttcagcaact caaggtgcaa ctccccagca accccctgta aattccctgc ccagctctca3901 cggccaccac ttcccaaatg tggctgcgcc aacccagaca tctaggccca aaacaccaaa3961 cagagccagc cccagaccct attatcctca gacacccaac aaccgccctc ccagcacaga4021 accttcagaa atcagtctgt caccagaaag actcaatgcc tccatagcag gactcttccc4081 tccacagatt aatattcctt tacctcctag gccaaattta aacaggggct ttgatcaaca4141 aggcctaaat ccaacaactt tgaaggccat cgggcaagca ccttcaaatc ttaccatgaa4201 tccttccaat tttgctaccc cacaaactca caaattagat tctgtggtag tgaattctgg4261 aaagcagtct aattctggag caacaaaacg ggcaagtcca agcaacagtc gcaggtctag4321 tcctgggtcc agtaggaaaa ccactccaag ccctgggagg caaaattcaa aagcccctaa4381 acttactctg gcctctcaga caaatgcagc cctattgcag aatgtggagt tgccgagaaa4441 tgtattggtc agtcccactc ctctggccaa tccccctgta cctgggagc tttcctaacaa4501 cagtgggctg aatcctcaga attctactgt gtctgtggct gcagttgggg gtgttgttga4561 ggataacaag gagagcttga atgtgcctca ggacagtgat tgccagaatt cccagagtag4621 gaaggaacag gtaaacattg aactaaaagc agtccctgcc caagaagtta aaatggttgt4681 ccctgaagat cagtccaaaa aggatgggca gccttcggat cctaacaaac ttcccagtgt4741 cgaagagaac aaaaatttgg tgtctcctgc tatgagggaa gcaccaacat cgttaagtca4801 acttcttgac aactctggag ctcccaatgt gacaattaaa ccccctgggc ttacagatct4861 ggaagtaaca cctccagtag tttctgggga ggacctcaaa aaagcatctg tcattcccac4921 actgcaggat ctgtcttctt ctaaagaacc ttctaattcc ctaaacttac ctcacagtaa4981 tgagctgtgt tcatcccttg tgcatcccga attgagtgag gtcagttcta acgttgcacc5041 aagcatccct ccagtaatgt caagacctgt tagctcttcc tccatttcca ctcccttgcc5101 cccaaatcaa ataactgtat ttgtcacttc caatcccatc acaacttcag ctaacacatc5161 agcagctttg ccaactcact tgcagtctgc attgatgtca acagttgtca caatgcccaa5221 tgcgggtagc aaggttatgg tttctgaggg acagtcagct gctcagtcta atgcccggcc5281 tcagttcatt acacctgtct ttatcaattc atcctcaata attcaggtta tgaaaggatc5341 acagccaagc acaattcctg cagccccact gacaaccaac tctggcctga tgcctccctc5401 tgttgcagtt gttggccctt tacacatacc tcagaacata aaattttctt ctgctcctgt5461 accgcctaat gccctctcca gtagtcctgc tccaaacatc cagacaggtc gacctttggt5521 ccttagctca cgagccaccc ctgttcagct tccttcccct ccttgtacgt cttctccagt5581 tgtcccttct catccccctg tgcagcaagt gaaagaattg aatccagatg aggctagccc5641 tcaggtgaac acctcagcag atcagaacac tcttccctct tcacagtcaa ccacaatggt5701 ttctcccctt ttgaccaata gtccagggtc ctctggcaac cggcgaagcc cagtctcgtc5761 tagtaagggc aaaggaaaag tggacaaaat tggccaaatt ttgttgacca aggcatgtaa5821 gaaagttaca ggctctcttg agaaagggga agaacaatat ggtgcagatg gagagactga5881 aggccaaggg ctagacacca cagctccggg gctcatggga acagagcagt tatccacaga5941 gctggacagt aaaaccccaa cgcccccagc acccactctg ctaaaaatga cctctagccc
6001 tgtgggcccg ggcactgcct cagcaggacc cagcttacct ggcggtgctc tccccaccag6061 tgtacgctcg atagtaacca ctctggtacc ctccgagctc atctccgccg taccgaccac6121 aaaaagcaat catggtggca tagcatctga gtcacttgcg ggtggcctag tggaggagaa6181 ggtgggatcc catccagaac ttctacccag catagccccg tcgcagaatt tagtctcaaa6241 ggaaacttca accacagcac tgcaggcctc tgttgccaga ccagagctgg aggtaaatgc6301 tgccatagtc tctggacaaa gcagtgagcc caaagagata gttgaaaagt ccaaaatccc6361 aggccgaaga aactcccgaa ctgaagagcc aactgtggcc tctgaaagtg tggaaaatgg6421 acatcgtaaa cgatcttctc gacctgcttc agcctccagc tctactaaag acataaccag6481 tgcggtgcaa tccaagcgaa gaaaatccaa gtaaacaagc aggactgcga cttgatactt6541 ggaaatgtgt gtgactttta caaagagcaa ttttgagctg tgactttttt aaatcaattt6601 ctgtacagtt agtaatttta ataatgtggc ccttttccta gtccctgcaa cctgtttcat6661 aaagtgcaat ggggaaagca ggactgttga gcccttttgg tgttgcgagt tgaagttcaa6721 ggtttctaaa atgttgtctt gtattgaaag gagctaatgc cattataaat gttactagtt6781 ttcacatttc ctaagcagcc tagagtacag ggtgagcatt tttagatctc ctaatgatgt6841 attgtgccgt ggaagtactg tgtgtgaata gcagtagtgg gggcaaaagc aatcttctca6901 tttggaaatg ttgtaaataa ttttattata tagtgttttg gatgtatttg ttgtagaaat6961 ggaccagtga ataaagagaa tctaaggatt tgtacaatgt gaaataacgt gttaaataaa7021 tgtcattgtc atagaacata aagttatgtt attggtaagg ga<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>112<211>2813<212>DNA<213>人類(Homo sapiens)<400>1121 atcggagtgt ggcagtgctg ggctggccgg cgggctgggc tgcggcccgc gcgcggccgg61 cgatgcaggg gggcaactcc ggggtccgca agcgcgaaga ggagggcgac ggggctgggg121 ctgtggctgc gccgccggcc atcgactttc ccgccgaggg cccggagccc gaatatgacg181 aatctgatgt tccagcagaa atccaggtgt taaaagaacc cctacaacag ccaaccttcc241 cttttgcagt tgcaaaccaa ctcttgctgg tttctttgct ggagcacttg agccacgtgc301 atgaaccaaa cccacttcgt tcaagacagg tgtttaagct actttgccag acgtttatca361 aaatggggct gctgtcttct ttcacttgta gtgacgagtt tagctcattg agactacatc421 acaacagagc tattactcac ttaatgaggt ctgctaaaga gagagttcgt caggatcctt481 gtgaggatat ttctcgtatc cagaaaatca gatcaaggga agtagccttg gaagcacaaa541 cttcacgtta cttaaatgaa tttgaagaac ttgccatctt aggaaaaggt ggatacggaa601 gagtatacaa ggtcaggaat aaattagatg gtcagtatta tgcaataaaa aaaatcctga661 ttaagggtgc aactaaaaca gtttgcatga aggtcctacg ggaagtgaag gtgctggcag721 gtcttcagca ccccaatatt gttggctatc acaccgcgtg gatagaacat gttcatgtga781 ttcagccacg agcagacaga gctgccattg agttgccatc tctggaagtg ctctccgacc841 aggaagagga cagagagcaa tgtggtgtta aaaatgatga aagtagcagc tcatccatta901 tctttgctga gcccacccca gaaaaagaaa aacgctttgg agaatctgac actgaaaatc961 agaataacaa gtcggtgaag tacaccacca atttagtcat aagagaatct ggtgaaattg1021 agtcgaccct ggagctccag gaaaatggct tggctggttt gtctgccagt tcaattgtgg1081 aacagcagct gccactcagg cgtaattccc acctagagga gagtttcaca tccaccgaag1141 aatcttccga agaaaatgtc aactttttgg gtcagacaga ggcacagtac cacctgatgc1201 tgcacatcca gatgcagctg tgtgagctct cgctgtggga ttggatagtc gagagaaaca
1261 agcggggccg ggagtatgtg gacgagtctg cctgtcctta tgttatggcc aatgttgcaa1321 caaaaatttt tcaagaattg gtagaaggtg tgttttacat acataacatg ggaattgtgc1381 accgagatct gaagccaaga aatatttttc ttcatggccc tgatcagcaa gtaaaaatag1441 gagactttgg tctggcctgc acagacatcc tacagaagaa cacagactgg accaacagaa1501 acgggaagag aacaccaaca catacgtcca gagtgggtac ttgtctgtac gcttcacccg1561 aacagttgga aggatctgag tatgatgcca agtcagatat gtacagcttg ggtgtggtcc1621 tgctagagct ctttcagccg tttggaacag aaatggagcg agcagaagtt ctaacaggtt1681 taagaactgg tcagttgccg gaatccctcc gtaaaaggtg tccagtgcaa gccaagtata1741 tccagcactt aacgagaagg aactcatcgc agagactatc tgccattcag ctgctgcaga1801 gtgaactttt ccaaaattct ggaaatgtta acctcaccct acagatgaag ataatagagc1861 aagaaaaaga aattgcagaa ctaaagaagc agctaaacct cctttctcaa gacaaagggg1921 tgagggatga cggaaaggat gggggcgtgg gatgaaagtg gacttaactt ttaaggtagt1981 taactggaat gtaaattttt aatctttatt agggtatagt tggtacaatg cttcgttgta2041 tttagtaagc ctttacaaga cttgttaaag atgtcagagt gccccaagct gccgttcctt2101 cccttcctgc cccacaagct ccttttcctg aatttcctac ctaaatatta accatatgcc2161 tagtctctga aactaaaaac ttggacctca tcctcaatta ttttctcctt tcaactctgt2221 tgaccctctg tctggtcttc ctctagaagg ttctaccgca gaaattgatg tgtgctccct2281 gccctcgtca ctgcccaagc ccgggcctgc acatactcac tggactgttc cagttttgac2341 agctgccagt cttcctgccc ctttcacact gcagctgaag ttcattacct gaaggacgcc2401 tcatcatttc attccttggc tccaaacctt ctgctgcctc taagataaaa gctcaacttc2461 ttaacagtgt acagtgtgca acttccaacc tttttatctg ttctctccac cttcagttta2521 gcgtcattcc aaaaccacac ccttgcaaag ctttgtactc cgcaccccag atgatctcca2581 ggcagctcag atctctttcc tgcctttgcc ctgcactgtt ccccggtact tcctccttta2641 ttgtagcact cagctcccca gccaatctgt acatccctca gaggcagcga tctgatgaat2701 tggtttttga atcccagaaa gggtctgcca tggagttggc agtcatcacg gtagatggcg2761 tatgattttg ctgaatttta aataaaatga aaaccataaa aaaaaaaaaa aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>113<211>3682<212>DNA<213>人類(Homo sapiens)<400>1131 gaccatcaga ccggcctgaa taccagaatc tctttgcaat gcactcgcct cgctcattac61 cagaaggagg ttttacctgc ctagtgacct ggttggtctg ggcatgaacc ccgagaggtg121 gaaactctca gactctcagg actgacagcc gagtggctgg ggactataaa tccgcgagaa181 ctgccctcgc gctgccatcc agctgggtag ccgggggagc gcgcgtgggg gctccgcgag241 tcgctcgccc ttggtttctg gggaagcctg ggggacgcgg ctgtggcgga ggcgccctgg301 gactcaggtc gcctggagcg tggcacgcag agccccaggc gcggagctga ggccgcgcgg361 ccgcgcttgg ccccagcggg cgtgggactg agcagtctgc tgccccccga catgtgaccc421 agccccgccg cccatgcggg ctcccggccg cccggccctg cggccgctgc cgctgccgcc481 gctgctgctg ttgctcctgg cggcgccttg gggacgggca gttccctgtg tctctggtgg541 tttgcctaaa cctgcaaaca tcaccttctt atccatcaac atgaagaatg tcctacaatg601 gactccacca gagggtcttc aaggagttaa agttacttac actgtgcagt atttcatata661 tgggcaaaag aaatggctga ataaatcaga atgcagaaat atcaatagaa cctactgtga721 tctttctgct gaaacttctg actacgaaca ccagtattat gccaaagtta aggccatttg
781 gggaacaaag tgttccaaat gggctgaaag tggacggttc tatccttttt tagaaacaca841 aattggccca ccagaggtgg cactgactac agatgagaag tccatttctg ttgtcctgac901 agctccagag aagtggaaga gaaatccaga agaccttcct gtttccatgc aacaaatata961 ctccaatctg aagtataacg tgtctgtgtt gaatactaaa tcaaacagaa cgtggtccca1021 gtgtgtgacc aaccacacgc tggtgctcac ctggctggag ccgaacactc tttactgcgt1081 acacgtggag tccttcgtcc cagggccccc tcgccgtgct cagccttctg agaagcagtg1141 tgccaggact ttgaaagatc aatcatcaga gttcaaggct aaaatcatct tctggtatgt1201 tttgcccgta tctattaccg tgtttctttt ttctgtgatg ggctattcca tctaccgata1261 tatccacgtt ggcaaagaga aacacccagc aaatttgatt ttgatttatg gaaatgaatt1321 tgacaaaaga ttctttgtgc ctgctgaaaa aatcgtgatt aactttatca ccctcaatat1381 ctcggatgat tctaaaattt ctcatcagga tatgagttta ctgggaaaaa gcagtgatgt1441 atccagcctt aatgatcctc agcccagcgg gaacctgagg ccccctcagg aggaagagga1501 ggtgaaacat ttagggtatg cttcgcattt gatggaaatt ttttgtgact ctgaagaaaa1561 cacggaaggt acttctctca cccagcaaga gtccctcagc agaacaatac ccccggataa1621 aacagtcatt gaatatgaat atgatgtcag aaccactgac atttgtgcgg ggcctgaaga1681 gcaggagctc agtttgcagg aggaggtgtc cacacaagga acattattgg agtcgcaggc1741 agcgttggca gtcttgggcc cgcaaacgtt acagtactca tacacccctc agctccaaga1801 cttagacccc ctggcgcagg agcacacaga ctcggaggag gggccggagg aagagccatc1861 gacgaccctg gtcgactggg atccccaaac tggcaggctg tgtattcctt cgctgtccag1921 cttcgaccag gattcagagg gctgcgagcc ttctgagggg gatgggctcg gagaggaggg1981 tcttctatct agactctatg aggagccggc tccagacagg ccaccaggag aaaatgaaac2041 ctatctcatg caattcatgg aggaatgggg gttatatgtg cagatggaaa actgatgcca2101 acacttcctt ttgccttttg tttcctgtgc aaacaagtga gtcacccctt tgatcccagc2161 cataaagtac ctgggatgaa agaagttttt tccagtttgt cagtgtctgt gagaattact2221 tatttctttt ctctattctc atagcacgtg tgtgattggt tcatgcatgt aggtctctta2281 acaatgatgg tgggcctctg gagtccaggg gctggccggt tgttctatgc agagaaagca2341 gtcaataaat gtttgccaga ctgggtgcag aatttattca ggtgggtgta ctctggcctc2401 ttggttcatt attttcaaac aagcacactt gtacaattat tttctgggta cttcccatat2461 gcacatagca ctgtaaaaaa tatttcccaa agatcactca ttttataaat accacttttt2521 cagaattggg tttattgcga gcaggaggag atacttaaaa catgcacata taccaggttg2581 gtggtaagtt ggtcgcatgt gaaaacctca actatttaat catcatgatt catattttga2641 gtgaatacat caggcacaga ccttcatgat atcacacact cttggctact ttaagaggcc2701 atctttaata ctttatgagt agttctggag tgtaaacata aacgagtatt cttttgtagt2761 cagaaaagtg tcctctcaat aatttagtag gggcttattg tctctcaaaa ctaacctaaa2821 agaaaatgac acattttata atagaatatt acatttattt ctggaagtgt gttttcaaaa2881 agatatttac atagtctgta aactagaaag tgttaggtaa agctctaggt tactgtgtta2941 ctattataat attaaacatt cgaataggca gtcgttcaaa gactctttgg aatatctatg3001 aatgaatatc ctctattctt ataatattaa aacccataag taaatatagg acatacaaga3061 gaaatgagtt aaatgactat gtaagggaga gtttattaaa atttgatgaa atttactgta3121 ggaactaaac tatgccataa aacaatagct ttctagttca tttccagtaa ctgttcccat3181 ctcctttacc acttgttaag aaaattaaat tcttcagtca cgctgcttta aaatgggaca3241 aaatctatta agttgaacca tatataattg tggatatttg gctgttttta atctgacaag3301 cagtaacttc atatggtttg ccttaatata tatttgtttt agtcatgaac tcataatcca3361 ttgatgctct ttcatgagaa gagatatcac ccatatttcc ttattgatat tattggtaca3421 ggcagacaac cctggtagga gagatggatt ctggggtcat gacctttcgt gattatccgc3481 aaatgcaaac agtttcagat ctaatggttt aatttaggga gtaattatat taatcagagt3541 gttctgttat tctcaatctt tatagaaacg attctgctgg ttttgaagaa cagatgtatt3601 acactaactg taaaagtagt tcaagagtga gaaagaataa attgttatta agagcaaaag
3661 aaaaataaag tgattgatga ta<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>114<211>2617<212>DNA<213>人類(Homo sapiens)<400>1141 gcgtccccct cggcgggctg ccgccgtgcc cgcgccggct ccccagcccg agcctgcccc61 ttgccctgat gaggtgcaaa gagcgggatc ggaggcgggg cctggccggg ctgtgagcgg121 cgtatgcaaa tcgagggtct cggggatgcg gatccaagac cctgggaagg tcttctttgg181 caatgtggat tcatctggga taaaacacaa tatttttaac cctccaatta ttgctcgata241 catccgtttg cacccaactc attatagcat tcgcagcact cttcgcatgg agttgatggg301 ctgtgattta aatagttgca gcatgccatt gggaatggag agtaaagcaa tatcagatgc361 acagattact gcttcatcct actttaccaa tatgtttgcc acctggtctc cttcaaaagc421 tcgacttcac ctccaaggga ggagtaatgc ctggagacct caggtgaata atccaaaaga481 gtggctgcaa gtggacttcc agaagacaat gaaagtcaca ggagtaacta ctcagggagt541 aaaatctctg cttaccagca tgtatgtgaa ggagttcctc atctccagca gtcaagatgg601 ccatcagtgg actctctttt ttcagaatgg caaagtaaag gtttttcagg gaaatcaaga661 ctccttcaca cctgtggtga actctctaga cccaccgtta ctgactcgct accttcgaat721 tcacccccag agttgggtgc accagattgc cctgaggatg gaggttctgg gctgcgaggc781 acaggacctc tactgagggt ggccactgca gcacctgcca ctgccgtcac ctctccctcc841 tcagctccag ggcagtgtcc ctccctggct tgccttctac ctttgtgcta aatcctagca901 gacactgcct tgaagcctcc tgaattaact atcatcagtc ctgcatttct ttggtggggg961 gccaggaggg tgcatccaat ttaacttaac tcttacctat tttctgcagc tgctcccaga1021 ttactccttc cttccaatat aactaggcaa aaagaagtga ggagaaacct gcatgaaagc1081 attcttccct gaaaagttag gcctctcaga gtcaccactt cctctgttgt agaaaaacta1141 tgtgatgaaa ctttgaaaaa gatatttatg atgttaacat ttcaggttaa gcctcatacg1201 tttaaaataa aactctcagt tgtttattat cctgatcaag catggaacaa agcatgtttc1261 aggatcagat caatacaatc ttggagtcaa aaggcaaatc atttggacaa tctgcaaaat1321 ggagagaata caataactac tacagtaaag tctgtttctg cttccttaca catagatata1381 attatgttat ttagtcatta tgaggggcac attcttatct ccaaaactag cattcttaaa1441 ctgagaatta tagatggggt tcaagaatcc ctaagtcccc tgaaattata taaggcattc1501 tgtataaatg caaatgtgca tttttctgac gagtgtccat agatataaag ccatttggtc1561 ttaattctga ccaataaaaa aataagtcag gaggatgcaa ttgttgaaag ctttgaaata1621 aaataacaat gtcttcttga aatttgtgat ggccaagaaa gaaaatgatg atgacattag1681 gcttctaaag gacatacatt taatatttct gtggaaatat gaggaaaatc catggttatc1741 tgagatagga gatacaaact ttgtaattct aataatgcac tcagtttact ctctccctct1801 actaatttcc tgctgaaaat aacacaacaa aaatgtaaca ggggaaatta tataccgtga1861 ctgaaaacta gagtcctact tacatagttg aaatatcaag gaggtcagaa gaaaattgga1921 ctggtgaaaa cagaaaaaac actccagtct gccatatcac cacacaatag gatccccctt1981 cttgccctcc acccccataa gattgtgaag ggtttactgc tccttccatc tgcctgaccc2041 cttcactatg actacacaga atctcctgat agtaaagggg gctggaggca aggataagtt2101 atagagcagt tggaggaagc atccaaagat tgcaacccag ggcaaatgga aaacaggaga2161 tcctaatatg aaagaaaaat ggatcccaat ctgagaaaag gcaaaagaat ggctactttt2221 ttctatgctg gagtattttc taataatcct gcttgaccct tatctgacct ctttggaaac
2281 tataacatag ctgtcacagt atagtcacaa tccacaaatg atgcaggtgc aaatggttta2341 tagccctgtg aagttcttaa agtttagagg ctaacttaca gaaatgaata agttgttttg2401 ttttatagcc cggtagagga gttaaccgca aaggtgatat ggttttactt cctgttatgt2461 ttaacttgat aatcttattt tggcattctt ttcccattga ctatatacat ctctatttct2521 caaatgttca tggaactagc tcttttattt tcctgctggt ttcttcagta atgagttaaa2581 taaaacattg acacatacaa acaaaaaaaa aaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>115<211>1567<212>DNA<213>人類(Homo sapiens)<400>1151 cgccccaccc gcgagccgca gccgcggccc cacagcttct ggggctgggg ccccggcagc61 cgggcaggcc ggcctgacct cgacctccgc cgtgcgggcc cgaccggtga gtccagcccg121 gcagtcgcag gacccggccg ccagcctctc cctccacctc tccctgcccc cagcgccagg181 cgcgggctgc gctcggtggc ggcggcgggg ccctcaggcg gccatggcgg caggcgccgg241 ggccgggtcc gcgccgcgct ggctgagggc gctgagcgag ccgctgagcg cggcgcagct301 gcggcgactg gaggagcacc gctacagcgc ggcgggcgtc tcgctgctcg agccgccgct361 gcagctctac tggacctggc tgctccagtg gatcccgctc tggatggccc ccaactccat421 caccctgctg gggctcgccg tcaacgtggt caccacgctc gtgctcatct cctactgtcc481 cacggccacc gaagaggcac catactggac atacctttta tgtgcactgg gactttttat541 ttaccagtca ctggatgcta ttgatgggaa acaagccaga agaacaaact cttgttcccc601 tttaggggag ctctttgacc atggctgtga ctctctttcc acagtattta tggcagtggg661 agcttcaatt gccgctcgct taggaactta tcctgactgg ttttttttct gctcttttat721 tgggatgttt gtgttttatt gcgctcattg gcagacttat gtttcaggca tgttgagatt781 tggaaaagtg gatgtaactg aaattcagat agctttagtg attgtctttg tgttgtctgc841 atttggagga gcaacaatgt gggactatac gattcctatt ctagaaataa aattgaagat901 ccttccagtt cttggatttc taggtggagt aatattttcc tgttcaaatt atttccatgt961 tatcctccat ggtggtgttg gcaagaatgg atccactata gcaggcacca gtgtcttgtc1021 acctggactc cacataggac taattattat actggcaata atgatctata aaaagtcagc1081 aactgatgtg tttgaaaagc atccttgtct ttatatccta atgtttggat gtgtctttgc1141 taaagtctca caaaaattag tggtagctca catgaccaaa agtgaactat atcttcaaga1201 cactgtcttt ttggggccag gtcttttgtt tttagaccag tactttaata actttataga1261 cgaatatgtt gttctatgga tggcaatggt gatttcttca tttgatatgg tgatatactt1321 tagtgctttg tgcctgcaaa tttcaagaca ccttcatcta aatatattca agactgcatg1381 tcatcaagca cctgaacagg ttcaagttct ttcttcaaag agtcatcaga ataacatgga1441 ttgaagagac ttccgaacac ttgctatctc ttgctgctgc tgtttcatgg aaggagatat1501 taaacatttg tttaattttt atttaagtgt tatacctatt tcagcaaata aaatatttca1561 ttgctta<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>116<211>3206
<212>DNA<213>人類(Homo sapiens)<400>1161 gtttataact tgaaaaatcc tctccgtctc ccttccctgc ctcctttcct ttccctttcc61 tctgccagta caactagacc cggcgtctgg cgtccccggt gcccagcatt ctgcggggca121 ggcggattaa ttggaattct tcaaaatgtc aggtgtggta cccacagccc ctgaacagcc181 tgcaggtgaa atggaaaatc aaacaaaacc accagatcca aggcctgatg ctcctcctga241 atacagttct cattttttac caggaccccc tggaacagct gtccctccac ctactggcta301 cccaggaggc ttgcctatgg gatactacag tccacagcaa cccagtacct tccctttgta361 ccagccagtt ggtggtatcc atcctgtccg gtatcagcct ggcaaatatc ctatgccaaa421 tcagtctgtt ccaataacat ggatgccagg gccaactcct atggcaaact gccctcctgg481 tctggaatac ttagttcagt tggacaacat acatgttctt cagcattttg agcctctgga541 aatgatgaca tgttttgaaa ctaataatag atatgatatt aaaaacaact cagaccagat601 ggtttacgtt gtaaccgaag acacagatga ctttaccagg aatgcctatc ggacactaag661 gcccttcgtc ctccgggtca ctgattgtat gggccgagaa atcatgacaa tgcagagacc721 cttcagatgc acctgctgtt gcttctgttg cccctctgcc agacaagagc tggaggtgca781 gtgtcctcct ggtgtcacca ttggctttgt tgcggaacat tggaacctgt gcagggcggt841 gtacagcatc caaaatgaga agaaagaaaa tgtgatgaga gttcgtgggc catgctcaac901 ctatggctgt ggttcagatt ctgtttttga ggtcaaatcc cttgatggca tatccaacat961 cggcagtatt atccggaagt ggaatggttt gttatcagca atggcagatg ctgaccattt1021 tgacattcac ttcccactag acctggatgt gaagatgaaa gccatgattt ttggagcttg1081 cttcctcatt gacttcatgt attttgaaag atctccacca caacgttcaa gatagagaga1141 cacagcaagc catcaactat ggttaatttt gaaaaatgga aaagttggat tgggcttaca1201 gtcagcactc agttatttgc aagtgtattt ctttgctttg tagagtattt ttattgggtg1261 ttaactttga cagctgagag tgggcttgca agaacacaat ctaaaagtgt gtttcaattg1321 agtatctctc tagtagaata ggagttcatc ctgaaaagct gtgactcatt aacccagtaa1381 acatatacaa agtaagctta aaacactata aacatgagat aagggaaaat gaatccagag1441 ttctcatatt aataggtagt gaaacaataa ggctttttag agcagacttt gttggcataa1501 aataacctgg cttctatccc taaccctttc ctacctttcc tctccgtcaa catgtcctca1561 tactgaagac aaacttgttt caatgatagt cttcattttt aaaaacaaaa aggcaggcag1621 acagaaataa tgatgttttc ttgcactaag aaggtactac ttgtacacat atatcaaaac1681 ctcattctgc aaagtttttg aaggtttcaa tgggaaattt gattttatta caaaataaaa1741 cattttttaa tgttaaagtt tatatattcc atgcttgttt tctcattcac tggcatggat1801 gatcaggagc tgcctatata tgaaggcaga atcagactat caggaaagga gctggccagg1861 gccacagcca gtcaagatct ctgagcaact tagagacatt ggtgtcatta tatgaagctt1921 gcatttaata catttataca taatacattt gtacatttaa ttcataacgt ctcttggtca1981 cagatgcctt atatataaaa taagttgcca gatctctaag attgcctagt acacctttgt2041 atctcatttg atgtgatacc cagaagagat cattgttttt tgtttttgtt tttgtttttt2101 tcaagaagat ccttcgtgat caccatgctg ttctcatggt aagaactgga gttatgtttt2161 taaatttgaa aatatgacat tttatgtagc actatataaa aagtgaaagc gacaaattcc2221 accgctgctt aatactgctt tgcttctttt tattgacatg atagatacat atgtatctac2281 acagagtaat aataataaaa cacagtaaac attctatttc tctatggtct acagcatgcc2341 agtaaataat atgtaggacc aataataaat tatcaattac acatttttgt gttaactaat2401 taaaagcata gtgtataagt gagtacactc taattaactt gcttctgttg cactttagtt2461 ttctacctgc atatggactg catttttttt tttaacacag tcagtatgta gaatgggatg2521 tattcttctg ctgctgctta ttaaataaag aaagcctgag tgttcttaga tggggttatt2581 ctgagatgag ggtcttagcc tacagttctt tttgaaatga aaggtgcttt gttttttaat2641 tatattcatc ttttcagggt aaatttgttt ttctgagttt ctcgtaatgc tcatttttac
2701 atgctgctac tagctttttt ttttaaaaaa agtaaaagtt gctgctttct aaaatattaa2761 ttgccttata tttgaaagtg ccattgcaat cgtaagtaga ctatgtattt cctataatga2821 tgtctgatat ttaaatagga aatcagacaa acaatattca gaaagtttaa gcatataaac2881 tttttatttt taacttgcct agatccctgt attccaaaac ctgctgcatc ataataaata2941 tatctatata tatttagcat aagacgtgat atttttaatt tcttttttaa aaaattatat3001 ttgtctctta gagttaaaat tttctttata taatattgtc atatgtcata gttttaatac3061 aattcacatg atttctatgt ttcttaatga tattttgttg tgtaaaattg atcggattga3121 ttaaaaaaca aattctctgg aatttgtgcg ttcatgcttt ttcgtattct ttatggcttt3181 taaataaata tacaatggtt aatagt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>117<211>5156<212>DNA<213>人類(Homo sapiens)<400>1171 gagaggcggg ggattggtat gcgagcgaat gtgcgagggg agggaggcgt cccggcggag61 cgtggtacta cgaccagcgc gggccggagg gggcgggggg atgcgccgcg gcggcggcgg121 cgcgggagct ggggttggtg tttggcggcg ccagagcagc ggatcccggt ctcgccgcag181 cagcagcgcg ggtgtcgtgc accgcctgaa gacgccgtac ctttctaccc tcccaccttt241 tttttttttt ttttaaataa ccggaaccaa tgaacgcagc cgggatcaga gctccggagg301 ccgccggtgc cgatgggacc aggctggcgc ccggcgggag cccgtgtctg aggcggcggg361 ggcggccgga ggagtcgccg gcggcggtgg tggcgcctcg cggagccggc gagctgcagg421 cggccggggc gccgctgcgc tttcacccgg cttctcctcg gcgccttcat cccgcctcga481 ctcctggccc agcgtggggc tggctgctgc ggcggcggcg ctgggctgcg ttgctggtgc541 tcgggctgct ggtagccgga gcggcggacg gatgcgagct tgtgccccgg cacctccgcg601 ggcggcgggc gactggctct gccgcaactg ccgcctcctc tcccgccgcg gcggccggcg661 atagcccggc gctcatgaca gatccctgca tgtcactgag tccaccatgc tttacagaag721 aagacagatt tagtctggaa gctcttcaaa caatacataa acaaatggat gatgacaaag781 atggtggaat tgaagtagag gaaagtgatg aattcatcag agaagatatg aaatataaag841 atgctactaa taaacacagc catctgcaca gagaagataa acatataacg attgaggatt901 tatggaaacg atggaaaaca tcagaagttc ataattggac ccttgaagac actcttcagt961 ggttgataga gtttgttgaa ctaccccaat atgagaagaa ttttagagac aacaatgtca1021 aaggaacgac acttcccagg atagcagtgc acgaaccttc atttatgatc tcccagttga1081 aaatcagtga ccggagtcac agacaaaaac ttcagctcaa ggcattggat gtggttttgt1141 ttggacctct aacacgccca cctcataact ggatgaaaga ttttatcctc acagtttcta1201 tagtaattgg tgttggaggc tgctggtttg cttatacgca gaataagaca tcaaaagaac1261 atgttgcaaa aatgatgaaa gatttagaga gcttacaaac tgcagagcaa agtctaatgg1321 acttacaaga gaggcttgaa aaggcacagg aagaaaacag aaatgttgct gtagaaaagc1381 aaaatttaga gcgcaaaatg atggatgaaa tcaattatgc aaaggaggag gcttgtcggc1441 tgagagagct aagggaggga gctgaatgtg aattgagtag acgtcagtat gcagaacagg1501 aattggaaca ggttcgcatg gctctgaaaa aggccgaaaa agaatttgaa ctgagaagca1561 gttggtctgt tccagatgca cttcagaaat ggcttcagtt aacacatgaa gtagaagtgc1621 aatactacaa tattaaaaga caaaacgctg aaatgcagct agctattgct aaagatgagg1681 cagaaaaaat taaaaagaag agaagcacag tctttgggac tctgcacgtt gcacacagct1741 cctccctaga tgaggtagac cacaaaattc tggaagcaaa gaaagctctc tctgagttga
1801 caacttgttt acgagaacga ctttttcgct ggcaacaaat tgagaagatc tgtggctttc1861 agatagccca taactcagga ctccccagcc tgacctcttc cctttattct gatcacagct1921 gggtggtgat gcccagagtc tccattccac cctatccaat tgctggagga gttgatgact1981 tagatgaaga cacaccccca atagtgtcac aatttcccgg gaccatggct aaacctcctg2041 gatcattagc cagaagcagc agcctgtgcc gttcacgccg cagcattgtg ccgtcctcgc2101 ctcagcctca gcgagctcag cttgctccac acgcccccca cccgtcacac cctcggcacc2161 ctcaccaccc gcaacacaca ccacactcct tgccttcccc tgatccagat atcctctcag2221 tgtcaagttg ccctgcgctt tatcgaaatg aagaggagga agaggccatt tacttctctg2281 ctgaaaagca atgggaagtg ccagacacag cttcagaatg tgactcctta aattcttcca2341 ttggaaggaa acagtctcct cctttaagcc tcgagatata ccaaacatta tctccgcgaa2401 agatatcaag agatgaggtg tccctagagg attcctcccg aggggattcg cctgtaactg2461 tggatgtgtc ttggggttct cccgactgtg taggtctgac agaaactaag agtatgatct2521 tcagtcctgc aagcaaagtg tacaatggca ttttggagaa atcctgtagc atgaaccagc2581 tttccagtgg catcccggtg cctaaacctc gccacacatc atgttcctca gctggcaacg2641 acagtaaacc agttcaggaa gccccaagtg ttgccagaat aagcagcatc ccacatgacc2701 tttgtcataa tggagagaaa agcaaaaagc catcaaaaat caaaagcctt tttaagaaga2761 aatctaagtg aactggctga cttgatggaa tcatgttcaa gtggcatctg taaactatta2821 tcccccaccc tccactcccc accttttttt tggtttaatt ttaggaatgt aactccattg2881 gggctttcca ggccggatgc catagtggaa catccagaag ggcaactgtc tactgtctgc2941 ttatttaagt gactatatat aatcaattca tcaagccagt tattactgaa aaatcattga3001 aatgagacag tttacagtca tttctgccta tttatttctg ctttgttctc agtgatgtat3061 atgcaacatt ttgttgaaag ccacgatgga cttacaagct ttaatggact cgtaagccag3121 catgggcttg caaaaatttc ttgtttacca gagcatcttc ttatctttcc acagagctat3181 ttacatcctg gactatataa cttaaaagaa gtaaaacgta attgcactac tgttttccag3241 actggaaaaa aaaaaaatct ctgcaagtga aactgtatag agtttataaa atgactatgg3301 ataggggact gttttcactt ttagatcaaa atgggttttt aagtagaacc tagggtttct3361 aattgacttg atttctggaa atgaaaaccc gcgcttttat tatgggaagc ttcttgaact3421 gcatttacta ttgtgaagtt tcaagtcccg ctgtaaagat catgttgttt tgttttcccc3481 agggctttca ctgtgattta ctgcattgca ggctgtatga taaaacacac ataatttaaa3541 gagagaaggc tcttgattcc ttatgcaagt ggaagagttg aaacttgatt gaaggactta3601 aaacattcac aaccttaagc cgaggtgggg ggatatgggg attcaggcaa ttgtttacac3661 actttgaata actgcaaagg atttacggtt tgtgaaaaat gtgtactgtg gaaaagataa3721 taaattgaag acattattgt gtgggattgt gctgattttt gttgataaca caaaaaacac3781 tatgttttct ggagagctgt gtaagctgtc ttgttgctta gttgcaatat aagaaatagt3841 gatgttttgg acgtaagttg tcaacaaatt tctattttat attgttatat ttttatgtag3901 tttgaaatgt aaaaatgttc taatatcaag attaacaaat ataaatttat ggtgcattta3961 gattgcgttg tattaattta taaagtatgg tgttcattaa attggtgggt tgtataaggg4021 tagcttttgt tgttaaaaaa acagtagaga gttaagttcc atatagcaac aaagtatgtt4081 aacatctagg gagtttctgc ttataccact ttaaaaatat gcaatcataa gtgatttggt4141 tactgcaatg cagatggatg tttggatgaa caactgatac attttagtta gaatgctttt4201 tcagcattat ggctaaaata tatgtctaac ccagtgctat ttaggtgaaa atgctaattg4261 ataaaccaga agtttctttt gagatttgct ttaaagaaat gctttagtaa gaatatgaac4321 aatttcctga tgtctcctat aaattgtgat tgtttattct attactattg ttaaaaactt4381 gaatggtatt tatattggct gatatttata tacttaatag attgagttct gtaagggcaa4441 aaacggattg aaatgaacat agcgttttgc actaatgata agataacctg agaggtaggg4501 ttgaggaaca cagggttgaa agctgttgga gaggggaaaa gttgtgcata aagaactgaa4561 aagggttctg gagtgttcat tcagagtgaa gggaaaactt tatccttcta tttcttataa4621 ccagacagga ggagttcttc cctttgaaaa ttgcaaaagg aatgagaact ttgcagttgg
4681 atgaatagag aagggaaaag ttgctggagc acggagtgaa gatgggagga gctgttagca4741 aggcccactg ctgctcctgg gtgagaaggg agctctggag caggactagc tgggggccgg4801 cactgctgct tagagtggag gaggctggcc aaagagactg tgggctgttt tcagtcaggg4861 agcatgtgca ttgtttgtgc tcaatttcag acactcattt ataaacaaat tcaaccaagg4921 gatatttact gctttatgtt gcttatgata attattttgc attaatacag tatacacatt4981 tgtaaattca acaggaaatt attgagtttt ggaaagctac agtaatttct gtattacatc5041 atttatatgt gaaaagttgg acatttctgt aagtttttaa aattatccat ttgttacttt5101 aacattttaa aattatggtg ttttcctgat tttaaaagca atattttcct tactgt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>118<211>2280<212>DNA<213>人類(Homo sapiens)<400>1181 tccagccaga aggatggggt ggctcccact cctgctgctt ctgactcaat gcttaggggt61 ccctgggcag cgctcgcgat tgaatgactt ccaagtgctc cggggcacag agctacagca121 cctgctacat gcggtggtgc ccgggccttg gcaggaggat gtggcagatg ctgaagagtg181 tgctggtcgc tgtgggccct taatggactg ccgggccttc cactacaacg tgagcagcca241 tggttgccaa ctgctgccat ggactcaaca ctcgccccac acgaggctgc ggcgttctgg301 gcgctgtgac ctcttccaga agaaagacta cgtacggacc tgcatcatga acaatggggt361 tgggtaccgg ggcaccatgg ccacgaccgt gggtggcctg ccctgccagg cttggagcca421 caagttcccg aatgatcaca agtacacgcc cactctccgg aatggcctgg aagagaactt481 ctgccgtaac cctgatggcg accccggagg tccttggtgc tacacaacag accctgctgt541 gcgcttccag agctgcggca tcaaatcctg ccgggaggcc gcgtgtgtct ggtgcaatgg601 cgaggaatac cgcggcgcgg tagaccgcac ggagtcaggg cgcgagtgcc agcgctggga661 tcttcagcac ccgcaccagc accccttcga gccgggcaag ttcctcgacc aaggtctgga721 cgacaactat tgccggaatc ctgacggctc cgagcggcca tggtgctaca ctacggatcc781 gcagatcgag cgagagttct gtgacctccc ccgctgcggg tccgaggcac agccccgcca841 agaggccaca actgtcagct gcttccgcgg gaagggtgag ggctaccggg gcacagccaa901 taccaccact gcgggcgtac cttgccagcg ttgggacgcg caaatccctc atcagcaccg961 atttacgcca gaaaaatacg cgtgcaaaga ccttcgggag aacttctgcc ggaaccccga1021 cggctcagag gcgccctggt gcttcacact gcggcccggc atgcgcgcgg ccttttgcta1081 ccagatccgg cgttgtacag acgacgtgcg gccccaggac tgctaccacg gcgcagggga1141 gcagtaccgc ggcacggtca gcaagacccg caagggtgtc cagtgccagc gctggtccgc1201 tgagacgccg cacaagccgc agttcacgtt tacctccgaa ccgcatgcac aactggagga1261 gaacttctgc cggaacccag atggggatag ccatgggccc tggtgctaca cgatggaccc1321 aaggacccca ttcgactact gtgccctgcg acgctgcgct gatgaccagc cgccatcaat1381 cctggacccc ccagaccagg tgcagtttga gaagtgtggc aagagggtgg atcggctgga1441 tcagcggcgt tccaagctgc gcgtggttgg gggccatccg ggcaactcac cctggacagt1501 cagcttgcgg aatcggcagg gccagcattt ctgcgggggg tctctagtga aggagcagtg1561 gatactgact gcccggcagt gcttctcctc ctgccatatg cctctcacgg gctatgaggt1621 atggttgggc accctgttcc agaacccaca gcatggagag ccaagcctac agcgggtccc1681 agtagccaag atggtgtgtg ggccctcagg ctcccagctt gtcctgctca agctggagag1741 atctgtgacc ctgaaccagc gtgtggccct gatctgcctg ccccctgaat ggtatgtggt1801 gcctccaggg accaagtgtg agattgcagg ctggggtgag accaaaggta cgggtaatga
1861 cacagtccta aatgtggcct tgctgaatgt catctctaac caggagtgta acatcaagca1921 ccgaggacgt gtgcgggaga gtgagatgtg cactgaggga ctgttggccc ctgtgggggc1981 ctgtgagggt gactacgggg gcccacttgc ctgctttacc cacaactgct gggtcctgga2041 aggaattata atccccaacc gagtatgcgc aaggtcccgc tggccagctg tcttcacgcg2101 tgtctctgtg tttgtggact ggattcacaa ggtcatgaga ctgggttagg cccagccttg2161 atgccatatg ccttggggag gacaaaactt cttgtcagac ataaagccat gtttcctctt2221 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaataaaaaa aaaaaaaaaa aaaaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>119<211>2077<212>DNA<213>人類(Homo sapiens)<400>1191 ccgagcgcca gcgcggggaa ccgggaaaag gaaaccgtgt tgtgtacgta agattcagga61 aacgaaacca ggagccgcgg gtgttggcgc aaaggttact cccagaccct tttccggctg121 acttctgaga aggttgcgca cagctgtgcc cggcagtcta gaggcgcaga agaggaagcc181 atcgcctggc cccggctctc tggaccttgt ctcgctcggg agcggaaaca gcggcagcca241 gagaactgtt ttaatcatgg acaaacaaaa ctcacagatg aatgcttctc acccggaaac301 aaacttgcca gttgggtatc ctcctcagta tccaccgaca gcattccaag gacctccagg361 atatagtggc taccctgggc cccaggtcag ctacccaccc ccaccagccg gccattcagg421 tcctggccca gctggctttc ctgtcccaaa tcagccagtg tataatcagc cagtatataa481 tcagccagtt ggagctgcag gggtaccatg gatgccagcg ccacagcctc cattaaactg541 tccacctgga ttagaatatt taagtcagat agatcagata ctgattcatc agcaaattga601 acttctggaa gttttaacag gttttgaaac taataacaaa tatgaaatta agaacagctt661 tggacagagg gtttactttg cagcggaaga tactgattgc tgtacccgaa attgctgtgg721 gccatctaga ccttttacct tgaggattat tgataatatg ggtcaagaag tcataactct781 ggagagacca ctaagatgta gcagctgttg ttgtccctgc tgccttcagg agatagaaat841 ccaagctcct cctggtgtac caataggtta tgttattcag acttggcacc catgtctacc901 aaagtttaca attcaaaatg agaaaagaga ggatgtacta aaaataagtg gtccatgtgt961 tgtgtgcagc tgttgtggag atgttgattt tgagattaaa tctcttgatg aacagtgtgt1021 ggttggcaaa atttccaagc actggactgg aattttgaga gaggcattta cagacgctga1081 taactttgga atccagttcc ctttagacct tgatgttaaa atgaaagctg taatgattgg1141 tgcctgtttc ctcattgact tcatgttttt tgaaagcact ggcagccagg aacaaaaatc1201 aggagtgtgg tagtggatta gtgaaagtct cctcaggaaa tctgaagtct gtatattgat1261 tgagactatc taaactcata cctgtatgaa ttaagctgta aggcctgtag ctctggttgt1321 atacttttgc ttttcaaatt atagtttatc ttctgtataa ctgatttata aaggtttttg1381 tacatttttt aatactcatt gtcaatttga gaaaaaggac atatgagttt ttgcatttat1441 taatgaaact tcctttgaaa aactgctttg aattatgatc tctgattcat tgtccatttt1501 actaccaaat attaactaag gccttattaa tttttatata aattatatct tgtcctatta1561 aatctagtta caatttattt catgcataag agctaatgtt attttgcaaa tgccatatat1621 tcaaaaaagc tcaaagataa ttttctttac tattatgttc aaataatatt caatatgcat1681 attatcttta aaaagttaaa tgttttttta atcttcaaga aatcatgcta cacttaactt1741 ctcctagaag ctaatctata ccataatatt ttcatattca caagatatta aattaccaat1801 tttcaaatta ttgttagtaa agaacaaaat gattctctcc caaagaaaga cacattttaa1861 atactccttc actctaaaac tctggtatta taacttttga aagttaatat ttctacatga
1921 aatgtttagc tcttacactc tatccttcct agaaaatggt aattgagatt actcagatat1981 taattaaata caatatcata tatatattca cagagtataa acctaaataa tgatatatta2041 gattcaaata tttgaaataa aaacttgatt tttttgt<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>120<211>1885<212>DNA<213>人類(Homo sapiens)<400>1201 ttcctaggcc accatagcgg ctggcggagg gagcgcgcgc cttgctggcc tggagggggc61 gggggccgtg gcggctttaa agcgcccagc ccaggcgtcg cggggtgggg cggctctggc121 ggctgcgggg cgcagggcgc agcggccaag cggggtcccc ggaagcacag ctggggtgtc181 tccacctacg actggccgcg cgccttttct ctcccgcgcc agggaaggag cggctgcggc241 ccccgccggg cggaggcacg gggggcgtac gaggggcgga ggggaccgcg tcgcggagga301 gatggcgcgg cacgtgcggt gacggcaccc gagccctgag ggtcccagcc ccgcgctccg361 cgtccccggg acagcatgga gcgcccggag cccgagctga tccggcagag ctggcgggca421 gtgagccgca gcccgctgga gcacggcacc gtcctgtttg ccaggctgtt tgccctggag481 cctgacctgc tgcccctctt ccagtacaac tgccgccagt tctccagccc agaggactgt541 ctctcctcgc ctgagttcct ggaccacatc aggaaggtga tgctcgtgat tgatgctgca601 gtgaccaatg tggaagacct gtcctcactg gaggagtacc ttgccagcct gggcaggaag661 caccgggcag tgggtgtgaa gctcagctcc ttctcgacag tgggtgagtc tctgctctac721 atgctggaga agtgtctggg ccctgccttc acaccagcca cacgggctgc ctggagccaa781 ctctacgggg ccgtagtgca ggccatgagt cgaggctggg atggcgagta agaggcgacc841 ccgcccggca gcccccatcc atctgtgtct gtctgttggc ctgtatctgt tgtagcccag901 gctccccaag cttccctgca tcttggtcct tgtccccttg gccacactgg agaggtgatg961 gggcagggct gggtctcagt atcctagagt ccagctgcag aaggagtggc ttttcctcca1021 ggaaggggct tctgggtgtc ccctcatccc cagtagcctc tttcttgcgt ttctttttac1081 cttttttggc actccctctg accccgcgat gagtgttttg gtggcagagg tgggatgagc1141 tggaaaggta tggaggtggg agaggatggg gctcttctgt ctgtcctgct tcttcaggtg1201 agtgcaggcc aaggcggggg tgagatggct gagcttccag cgccttctgt cctgcctgcc1261 cagtcccttc actgctttcc tgccccaaga tggcttgctt ttcacaaata aagagaaaga1321 gcagctttag ccttcttggt ggaatcccag gcagtgggag cagaatcaga actgccaggg1381 aagggaaggg ggacctgggt ctcaatgggt ctcatttgag tctcgcgggc tgtgcagatg1441 ccctgacaga gtcggtttcc tttggcggca ttccctttcc ctcattcagc acttctgctg1501 ggaactccct gactattccg ctgctgcagg aacccagcta gctggccagg tggggagggg1561 ctggggaccg gccaggaagg aggggtgact tcatcccaga gagacccgag ttcccccagc1621 ccttcatcac caacccgctc ctgcaggagt gagtcttacc tcccctggcc ctcctttctg1681 gctcagcctg cagcgactgt gaggccacag ctcctcagat tcactgcccg ctgtgtgcca1741 gtactcaggc agctggagag aagagaaggc agcagcagag gcccccgccc tcaccccagc1801 catctgcact tgtaccattt gctctgtgct gactgtggtc ctataaattc atgagaaata1861 aactggttct gtgtgcaaaa aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142
<210>121<211>1763<212>DNA<213>人類(Homo sapiens)<400>1211 cttctggtaa ggaggccccg tgatcagctc cagccatttg cagtcctggc tatcccagga61 gcttacataa agggacaatt ggagcctgag aggtgacagt gctgacacta caaggctcgg121 agctccgggc actcagacat catgagttgg tccttgcacc cccggaattt aattctctac181 ttctatgctc ttttatttct ctcttcaaca tgtgtagcat atgttgctac cagagacaac241 tgctgcatct tagatgaaag attcggtagt tattgtccaa ctacctgtgg cattgcagat301 ttcctgtcta cttatcaaac caaagtagac aaggatctac agtctttgga agacatctta361 catcaagttg aaaacaaaac atcagaagtc aaacagctga taaaagcaat ccaactcact421 tataatcctg atgaatcatc aaaaccaaat atgatagacg ctgctacttt gaagtccagg481 aaaatgttag aagaaattat gaaatatgaa gcatcgattt taacacatga ctcaagtatt541 cgatatttgc aggaaatata taattcaaat aatcaaaaga ttgttaacct gaaagagaag601 gtagcccagc ttgaagcaca gtgccaggaa ccttgcaaag acacggtgca aatccatgat661 atcactggga aagattgtca agacattgcc aataagggag ctaaacagag cgggctttac721 tttattaaac ctctgaaagc taaccagcaa ttcttagtct actgtgaaat cgatgggtct781 ggaaatggat ggactgtgtt tcagaagaga cttgatggca gtgtagattt caagaaaaac841 tggattcaat ataaagaagg atttggacat ctgtctccta ctggcacaac agaattttgg901 ctgggaaatg agaagattca tttgataagc acacagtctg ccatcccata tgcattaaga961 gtggaactgg aagactggaa tggcagaacc agtactgcag actatgccat gttcaaggtg1021 ggacctgaag ctgacaagta ccgcctaaca tatgcctact tcgctggtgg ggatgctgga1081 gatgcctttg atggctttga ttttggcgat gatcctagtg acaagttttt cacatcccat1141 aatggcatgc agttcagtac ctgggacaat gacaatgata agtttgaagg caactgtgct1201 gaacaggatg gatctggttg gtggatgaac aagtgtcacg ctggccatct caatggagtt1261 tattaccaag gtggcactta ctcaaaagca tctactccta atggttatga taatggcatt1321 atttgggcca cttggaaaac ccggtggtat tccatgaaga aaaccactat gaagataatc1381 ccattcaaca gactcacaat tggagaagga cagcaacacc acctgggggg agccaaacag1441 gtcagaccag agcaccctgc ggaaacagaa tatgactcac tttaccctga ggatgatttg1501 tagaaaatta actgctaact tctattgacc cacaaagttt cagaaattct ctgaaagttt1561 cttccttttt tctcttacta tatttattga tttcaagtct tctattaagg acatttagcc1621 ttcaatggaa attaaaactc atttaggact gtatttccaa attactgata tcagagttat1681 ttaaaaattg tttatttgag gagataacat ttcaactttg ttcctaaata tataataata1741 aaatgattga ctttatttgc aaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>122<211>4539<212>DNA<213>人類(Homo sapiens)<400>1221 acgtcatcgc cgcgcgccgg cttgccagga gctggagggg gaggtaggcg gggcggcgcg61 tgacctaagg cctctctgcc gcgcgcgcag gtacggggca gaagtcgcag gtacccagct121 gctgcccaca tttctggtcc agagtcccga accccgagca ctgggatgcc tggctactcc181 gagccaaggc actgatgttt gaactggaaa cttcaaaacg tttaataaga gtcttcagga
241 tgggtttgaa ctagacaagc tagaaatttc tttagaacac cagctctagc atgcatctcc301 cacttttggc tttcctggag aggagcttga agaggtggtt ctgcagacag ccacagtgat361 acttaggaaa ccagaggaat ggatttgact tttctgctag gattctctgt tatagtttct421 ccctgagttg taagaggcat ggaaatatac atgaaactga agaacctgca aggaagggaa481 gtggaacttt ccatgctgag tgaaaactaa ccaagtggca gttgtgactg aaaacactga541 aacctaccac gtccagattc actggattgg gggatagagg aacggtcaca gctagggaga601 aagaagtgat accggaaaag aaaacctaaa tgaagagaat gaggatgact gcacagtaga661 tggccacctc tacctccaca gaggcaaagt cagcctcgtg gtggaattat ttttttcttt721 atgatggttc caaggtaaag gaagaaggcg atccaacaag agctggcatt tgttactttt781 atccttccca gaccctgcta gaccaacagg agttgctttg tggacagatt gctggagttg841 tccgctgtgt ttctgacatt tctgactctc ctcctactct tgttcgtctg agaaaactga901 agtttgccat aaaagttgat ggagattacc tttgggtgct gggctgtgct gtggagctcc961 ctgatgtcag ctgcaagcgg tttctggatc agctagttgg attctttaat ttttacaatg1021 gacctgtttc cctagcttat gagaactgtt ctcaggaaga actgagcacg gagtgggaca1081 ccttcatcga gcaaattctg aaaaacacca gtgatctgca taagattttc aattccctct1141 ggaacttgga ccaaactaaa gtggagcccc tgttgttgct gaaggcagcc cgcattctgc1201 agacctgcca gcgctcgcct cacattctcg ctggctgcat cctctataaa ggactgattg1261 tcagcaccca actcccgccc tccctcaccg ccaaggtcct gcttcaccga acagcacctc1321 aggagcagag actccctacg ggagaggatg ccccgcagga acatggagcg gcattgcccc1381 cgaatgtcca gattatccct gtttttgtga ccaaagagga agccattagt ctccacgagt1441 tcccggtgga acagatgaca aggtctctag catctccagc aggactccag gatggttcag1501 cccagcacca tccaaagggt gggagcacat ctgccctgaa agaaaacgcc actggccatg1561 tggaatccat ggcctggacc accccagatc ccacatcccc tgacgaagct tgtccagatg1621 gcaggaagga gaacggatgc ttgtctggcc atgatctgga gagcatcagg cccgcaggac1681 tgcacaactc tgccaggggt gaggttcttg gcctcagctc ctccctgggg aaggaactag1741 tctttctcca agaagaactc gacttgtctg aaatccacat tccagaggct caggaagtgg1801 aaatggcctc aggtcatttt gccttcctac atgtgcctgt tccagatggc agggctcctt1861 actgcaaggc atctctcagc gcctccagca gcctggaacc cacgcctcct gaggacacag1921 ccatcagcag cttgcgccct ccctctgctc ctgagatgct gacccagcat ggagcccaag1981 agcagctcga agaccatcct ggccatagca gccaagcccc cattcccaga gcagaccctc2041 tccccagaag gacccgcagg cccttgttat tgcctcgctt agatccagga cagagaggaa2101 acaagcttcc cacgggggaa caaggcctgg atgaggatgt tgatggggtc tgtgaaagcc2161 acgcagcccc tggtctggaa tgcagttcag gctcagcaaa ctgtcagggt gctggcccct2221 ctgcagatgg aatcagctcc aggctgacac cagcagagtc ctgcatgggg ctcgtgagga2281 tgaatctcta cactcactgc gtcaaagggc tggtgctgtc cctgctggct gaggagccgc2341 tgctgggaga cagcgcagcc atagaggaag tgtaccacag cagcctggct tcactgaatg2401 ggctggaagt ccacctgaaa gagacgctgc ccagggatga ggcagcctcc acgagcagca2461 cctacaactt cacacattac gaccgcattc agagcttgct gatggcaaac ctgccgcagg2521 tggccacccc gcaggatcgc cgcttcctcc aggccgtcag cctgatgcat agcgaatttg2581 cccagctgcc cgcgctttat gaaatgactg tcagaaatgc ctccacggct gtgtacgcct2641 gttgcaaccc catccaggag acatatttcc agcagctggc acctgcagca cggagctccg2701 gcttcccaaa ccctcaggat ggcgccttca gcctctccgg caaagcaaag cagaagctgc2761 tgaagcacgg ggtgaacttg ctctgaactg cacccaggag gtgactggga aggagaaaac2821 cagcaaagga agctctgcct tttataattg aaaaggcccc tctattttat ttttcttgaa2881 aacattccct tttttaggaa ccaaatgata tttgagtttt tgttattcct tttgcagatt2941 gggatgtgtt ttgggggcag gggttagttc ttcaggtcgg cagacccaga gcacttgata3001 aagaactgta tttaatcggt agtgttgggg ccgggacggg cttggctccc tctctgccat3061 actgagcctg aggtatttca tatctcctgc tgttccatcc cagcttgaat tggtgccaca
3121 agcttccaag ttggcatttt ttctagaacc tgatcgtcca ctagcccaga gtgtgtgtgt3181 tcaaccccca caccaggtgg tggtaggcgg tgtgactgca cagcgaggtg ccggatctgt3241 gagcaggccg actccactcc cacgccgcag gtaggtttct ccagtgcgct cttgctggga3301 ggtccggatc gttcctgcag ggaagcggca gcacacggag accacttggt tgaattctgt3361 tggaactcta ctcaaatcta ggggcgtctt ctttggaccc acaatggggg caagccttaa3421 taatatggaa gggagtttgg gctttagaga tccctttata aaagctctgg gggctgagcc3481 ctgagaattc agtgacaaca ggaccaacct gcgctgcctt tgactacaag tgggccgtgc3541 agctggttcc tctcgagcga gtgtccctaa ataggagttt acaagatgtc tgggggtaaa3601 agcactgtgc ttttcagtgg tggctgcgtg aaagggagcg acactcagct gtgtgttcct3661 gggcttgtgt ggtacttaga acctcagttc tattacgtta tagtcagaca tttttttgac3721 agtatgagac agactgcagg atgaaaatat ttgtcaaaat cttaactgaa tgtttactgg3781 aagtacttga gattccattt gagagttgta ttgttaataa tttcatgtca gtgaactgat3841 atctgatgtt tatgatatgg tgtctttttc ttgaaacaag cttccaaggg ctagaaataa3901 aatagccaaa aaatgctgga gttctgagta attaaatggc agcatttttt tgtgacaaag3961 gtaagggtta agacagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgcgcgcg4021 cgcgcgcgcg cgtaacgtgg gcgcatccct cttttccttc cctgggttca gtgtggctgg4081 gtaaggaccg tctgtttgta gggctgccag gctgcagcct gctgctccag ggagcaccag4141 ctgcagctga tccaatacac caagcctgtg tctccctctt ctatcacctc tctccaggat4201 ctctgctgtc tcttggatcc catctgccta gatggaagag gatcctatcc gaagctagga4261 taaatgttgt cttactcctc tgctatgttc tcccagaaaa aattgattac aagttctctg4321 ctgtggttgc tgcagctcca ggaagtcccc gcaatgtctc acgttgtctt tgaccagtgg4381 tccccagtac caggccagcg aagacaactt tataatgtca tttgtgttgt gaaaattctt4441 ccactgaccc aaaatggaac cgtacaaagc ctatccgtgt atatggaaaa gtctcatgca4501 cctggattaa ctcagaaaaa gtaaagtcct gaaacttca<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>123<211>1502<212>DNA<213>人類(Homo sapiens)<400>1231 atcacaatca gaagacagga gctgcagaac agaacacttt ctcatgtcca gggtcagatt61 acaagagcac tcaagacttt actgacgaaa actcaggaaa tcctctatca caaagaggtt121 tggcaactaa actaagacat taaaaggaaa ataccagatg ccactctgca ggttgcaata181 actactactt actggataca ttcaaaccct ccagaatcaa cagttatcag gtaaccaaca241 agaaatgcaa gccgtcgaca acctcacctc tgcgcctggt aacaccagtc tgtgcaccag301 agactacaaa atcacccagg tcctcttccc actgctctac actgtcctgt tttttgttgg361 acttatcaca aatggcctgg cgatgaggat tttctttcaa atccggagta aatcaaactt421 tattattttt cttaagaaca cagtcatttc tgatcttctc atgattctga cttttccatt481 caaaattctt agtgatgcca aactgggaac aggaccactg agaacttttg tgtgtcaagt541 tacctccgtc atattttatt tcacaatgta tatcagtatt tcattcctgg gactgataac601 tatcgatcgc taccagaaga ccaccaggcc atttaaaaca tccaacccca aaaatctctt661 gggggctaag attctctctg ttgtcatctg ggcattcatg ttcttactct ctttgcctaa721 catgattctg accaacaggc agccgagaga caagaatgtg aagaaatgct ctttccttaa781 atcagagttc ggtctagtct ggcatgaaat agtaaattac atctgtcaag tcattttctg841 gattaatttc ttaattgtta ttgtatgtta tacactcatt acaaaagaac tgtaccggtc
901 atacgtaaga acgaggggtg taggtaaagt ccccaggaca aaggtgaacg tcaaagtttt961 cattatcatt gctgtattct ttatttgttt tgttcctttc cattttgccc gaattcctta1021 caccctgagc caaacccggg atgtctttga ctgcactgct gaaaatactc tgttctatgt1081 gaaagagagc actctgtggt taacttcctt aaatgcatgc ctggatccgt tcatctattt1141 tttcctttgc aagtccttca gaaattcctt gataagtatg ctgaagtgcc ccaattctgc1201 aacatctctg tcccaggaca ataggaaaaa agaacaggat ggtggtgacc caaatgaaga1261 gactccaatg taaacaaatt aactaaggaa atatttcaat ctctttgtgt tcagaactcg1321 ttaaagcaaa gcgctaagta aaaatattaa ctgacgaaga agcaactaag ttaataataa1381 tgactctaaa gaaacagaag attacaaaag caattttcat ttacctttcc agtatgaaaa1441 gctatcttaa aatatagaaa actaatctaa actgtagctg tattagcagc aaaacaaacg1501 ac<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>124<211>2875<212>DNA<213>人類(Homo sapiens)<400>1241 gaattctccg gagctgaaaa aggatcctga ctgaaagcta gaggcattga ggagcctgaa61 gattctcagg ttttaaagac gctagagtgc caaagaagac tttgaagtgt gaaaacattt121 cctgtaattg aaaccaaaat gtcatttata gatccttacc agcacattat agtggagcac181 cagtattccc acaagtttac ggtagtggtg ttacgtgcca ccaaagtgac aaagggggcc241 tttggtgaca tgcttgatac tccagatccc tatgtggaac tttttatctc tacaacccct301 gacagcagga agagaacaag acatttcaat aatgacataa accctgtgtg gaatgagacc361 tttgaattta ttttggatcc taatcaggaa aatgttttgg agattacgtt aatggatgcc421 aattatgtca tggatgaaac tctagggaca gcaacattta ctgtatcttc tatgaaggtg481 ggagaaaaga aagaagttcc ttttattttc aaccaagtca ctgaaatggt tctagaaatg541 tctcttgaag tttgctcatg cccagaccta cgatttagta tggctctgtg tgatcaggag601 aagactttca gacaacagag aaaagaacac ataagggaga gcatgaagaa actcttgggt661 ccaaagaata gtgaaggatt gcattctgca cgtgatgtgc ctgtggtagc catattgggt721 tcaggtgggg gtttccgagc catggtggga ttctctggtg tgatgaaggc attatacgaa781 tcaggaattc tggattgtgc tacctacgtt gctggtcttt ctggctccac ctggtatatg841 tcaaccttgt attctcaccc tgattttcca gagaaagggc cagaggagat taatgaagaa901 ctaatgaaaa atgttagcca caatcccctt ttacttctca caccacagaa agttaaaaga961 tatgttgagt ctttatggaa gaagaaaagc tctggacaac ctgtcacctt tactgacatc1021 tttgggatgt taataggaga aacactaatt cataatagaa tgaatactac tctgagcagt1081 ttgaaggaaa aagttaatac tgcacaatgc cctttacctc ttttcacctg tcttcatgtc1141 aaacctgacg tttcagagct gatgtttgca gattgggttg aatttagtcc atacgaaatt1201 ggcatggcta aatatggtac ttttatggct cccgacttat ttggaagcaa attttttatg1261 ggaacagtcg ttaagaagta tgaagaaaac cccttgcatt tcttaatggg tgtctggggc1321 agtgcctttt ccatattgtt caacagagtt ttgggcgttt ctggttcaca aagcagaggc1381 tccacaatgg aggaagaatt agaaaatatt accacaaagc atattgtgag taatgatagc1441 tcggacagtg atgatgaatc acacgaaccc aaaggcactg aaaatgaaga tgctggaagt1501 gactatcaaa gtgataatca agcaagttgg attcatcgta tgataatggc cttggtgagt1561 gattcagctt tattcaatac cagagaagga cgtgctggga aggtacacaa cttcatgctg1621 ggcttgaatc tcaatacatc ttatccactg tctcctttga gtgactttgc cacacaggac
1681 tcctttgatg atgatgaact ggatgcagct gtagcagatc ctgatgaatt tgagcgaata1741 tatgagcctc tggatgtcaa aagtaaaaag attcatgtag tggacagtgg gctcacattt1801 aacctgccgt atcccttgat actgagacct cagagagggg ttgatctcat aatctccttt1861 gacttttctg caaggccaag tgactctagt cctccgttca aggaacttct acttgcagaa1921 aagtgggcta aaatgaacaa gctccccttt ccaaagattg atccttatgt gtttgatcgg1981 gaagggctga aggagtgcta tgtctttaaa cccaagaatc ctgatatgga gaaagattgc2041 ccaaccatca tccactttgt tctggccaac atcaacttca gaaagtacaa ggctccaggt2101 gttccaaggg aaactgagga agagaaagaa atcgctgact ttgatatttt tgatgaccca2161 gaatcaccat tttcaacctt caattttcaa tatccaaatc aagcattcaa aagactacat2221 gatcttatgc acttcaatac tctgaacaac attgatgtga taaaagaagc catggttgaa2281 agcattgaat atagaagaca gaatccatct cgttgctctg tttcccttag taatgttgag2341 gcaagaagat ttttcaacaa ggagtttcta agtaaaccca aagcatagtt catgtactgg2401 aaatggcagc agtttctgat gctgaggcag tttgcaatcc catgacaact ggatttaaaa2461 gtacagtaca gatagtcgta ctgatcatga gagactggct gatactcaaa gttgcagtta2521 cttagctgca tgagaataat actattataa gttaggtgac aaatgatgtt gattatgtaa2581 ggatatactt agctacattt tcagtcagta tgaacttcct gatacaaatg tagggatata2641 tactgtattt ttaaacattt ctcaccaact ttcttatgtg tgttcttttt aaaaattttt2701 tttcttttaa aatatttaac agttcaatct caataagacc tcgcattatg tatgaatgtt2761 attcactgac tagatttatt cataccatga gacaacacta tttttattta tatatgcata2821 tatatacata catgaaataa atacatcaat ataaaaataa aaaaaaacgg aattc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>125<211>1783<212>DNA<213>人類(Homo sapiens)<400>1251 aaggaataaa gttgctgatt cattccttta cactgaaacc ctttgttgtg ccctcctctt61 ccttcctctt tatagggaga cactctgaga aagagcacat tgtgggggcc cactccatgt121 gatgtttgct tggttgcctg ttcccttttc tacctgcaga gcacggttcc cataagggcg181 gcgagatcag cctcctgtct catctggaag accaccactc tggggtctca gaggaatgat241 ggaagccttg gggtttctaa aattggaagt gaatggcccc atggtgacgg tggccctgtc301 agtggctctc ttggccctcc tgaaatggta ctccacatca gcattctcaa gactggagaa361 gttaggcctc agacatccca agccttctcc tttcattgga aacttgacat ttttccgcca421 gggtttttgg gaaagccaaa tggagctcag aaagctgtat ggacctctgt gtgggtacta481 tcttggtcgt cggatgttta ttgttatttc tgagccagac atgatcaagc aggtgttggt541 tgagaacttc agtaacttta ccaacagaat ggcgtcgggt ttggagttca agtcggtagc601 cgacagcgtt ctgtttttac gtgacaaaag atgggaagag gtcagaggtg ccctgatgtc661 tgctttcagt cctgaaaagc tgaacgagat ggttcccctc atcagccaag cctgcgacct721 tctcctggct catttaaaac gctatgcgga atctggggac gcatttgaca tccagaggtg781 ctactgcaat tacaccacag atgtggttgc cagcgtcccg tttggcaccc cggtggactc841 ctggcaggcc cctgaggatc cctttgtgaa acactgcaag cgtttcttcg aattctgcat901 ccccagacct atcctggttt tactcttatc atttccatcc ataatggtcc cactggcccg961 gattttgccc aataagaacc gagacgaact gaatggcttt tttaacaaac tcattaggaa1021 tgtgattgcc ttgcgggacc agcaagctgc cgaagagagg cggagagact tcctccaaat1081 ggtcctggat gcccgacatt ctgcaagtcc catgggcgtg caagactttg acatcgtcag
1141 agacgttttc tcctctactg ggtgcaagcc gaacccttcc cggcaacaccagcccagcccc1201 tatggccagg cctttgactg tggatgagat tgtgggccag gccttcatct tcctcatcgc1261 tggctatgaa atcatcacca acacactttc ttttgccacc tacctactgg ccaccaaccc1321 tgactgccaa gagaagcttc tgagagaggt agacgttttt aaggagaaac acatggcccc1381 tgagttctgc agcctcgagg aaggcctgcc ctatctggac atggtgattg cagagacgct1441 gaggatgtac ccgccagctt tcagattcac acgggaggca gctcaggact gcgaggtgct1501 ggggcagcgc atccccgcag gcgctgtgct agagatggcc gtgggtgccc tgcaccatga1561 ccctgagcac tggccaagcc cggagacctt caaccctgaa aggtaccgct gcagctagaa1621 tccaaatctg ccctaggtcc aaaaaatggt gtctatatca agatcgtatc ccgctgacac1681 agaaggctgc cgggtggggg gagggcaccc ccaaattcaa agaaaaccct aagtgtggat1741 gttcagaatt ttggaaaaat gtcactgaag tgattgaaag ccg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>126<211>18209<212>DNA<213>人類(Homo sapiens)<400>1261 gaagccgcat ccagacaaaa gctgccgcat ccctgccctg cccaacccct ggagggattc61 gagtttggtg cttgtccccg tctgattctc agcgccaaac tttttgctag ttcagagatt121 ccaagagtct gatgagttac tctgagagga aaccctctgc ctgttgttga ggaggactga181 gcacagtgct taggcgctga gggggaaaaa gagggggaaa aaaaagaaaa tgatttcctg241 ggaagttgtc catacagtat tcctgtttgc tcttctttat tcttccctag ctcaagatgc301 gagcccccag tcagagatca gagctgagga aattcccgag ggggcctcca cgttggcttt361 tgtgtttgat gtgactggtt ctatgtatga tgatttagtt caggtgattg aaggggcttc421 caaaattttg gagacgtctt tgaaaagacc taaaagacct cttttcaact ttgcgttggt481 gcctttccat gatccagaaa ttggcccagt gacaattacc acagatccca agaaatttca541 atatgaactc agagaactgt atgttcaggg tggtggtgat tgcccagaaa tgagtattgg601 agctataaaa attgccttgg aaatttctct tcctggttct ttcatctatg ttttcactga661 tgctcggtcc aaagattacc ggctcaccca tgaggtgctg caacttatcc aacagaaaca721 gtcacaagtc gtatttgttc tgactggaga ttgtgatgac aggacccata ttggatataa781 agtctatgaa gaaattgcct ctacaagttc tggtcaagtg ttccatctgg acaaaaaaca841 agttaatgag gtattaaaat gggtagaaga agcagtacag gcctccaaag ttcacctttt901 atccacagat catttggaac aggctgtaaa tacttggaga attccttttg atcccagcct961 gaaagaggtc actgtgtctt tgagtgggcc ttctccaatg attgaaattc gcaatccttt1021 agggaagctg ataaaaaagg gatttggcct gcatgagcta ttaaatatcc ataactctgc1081 caaagtagtg aatgtgaaag agccagaggc tggaatgtgg acagtgaaga cctcaagcag1141 tggaaggcac tctgttcgca ttactggcct cagtactatt gatttccgag ctggcttttc1201 tcgaaagccc accctggact tcaaaaaaac agtcagcaga ccagtgcaag gaatacctac1261 ctatgtactg ctcaatactt ctggaatttc cactccagct agaatagatc ttcttgaact1321 tttgagtatc tcaggaagtt ctcttaagac tattcctgtt aaatattacc cacatcgaaa1381 accttatggc atatggaata tttctgactt tgtaccacca aatgaagctt tctttctcaa1441 agtaacaggc tatgataaag atgattacct cttccagaga gtatcaagtg tttccttttc1501 tagtattgtc ccagatgctc ccaaagttac gatgcctgag aaaaccccag gatactatct1561 gcagccgggc caaattccct gctctgttga cagtcttttg ccctttacct tgagctttgt1621 cagaaatgga gttacacttg gagtagacca gtatttgaaa gaatctgcca gtgtgaactt
1681 agatattgca aaggtcactt tgtctgacga aggtttctat gaatgcattg ctgtcagcag1741 tgcaggtact ggacgggcac agacattttt tgacgtatca gagccccctc cggtcatcca1801 agtgcctaac aatgttacag tcactcctgg agagagagca gttttaacat gtctcatcat1861 cagtgcggtg gattacaatc taacctggca gaggaatgac agagatgtca gactggcaga1921 gccagcgaga attaggacct tggctaatct gtcattggag ctaaagagtg tgaaattcaa1981 cgatgctgga gagtatcatt gtatggtttc tagtgaaggt ggatcatcag ccgcttcagt2041 tttcctcaca gtgcaagaac cacccaaagt cactgtgatg cccaagaatc agtctttcac2101 aggagggtct gaggtctcca tcatgtgttc tgcaacaggt tatcccaaac caaagattgc2161 ctggaccgtt aacgatatgt ttatcgtggg ttcacacagg tataggatga cctcagatgg2221 taccttattt atcaaaaatg cagctcccaa agatgcaggg atctatggtt gcctagcaag2281 taattcagct ggaacagata aacagaattc tactctcaga tacattgaag cccctaagtt2341 gatggtagtt cagagtgagc tcttggttgc ccttggggat ataaccgtta tggaatgcaa2401 aacctctggt attcctccac ctcaagttaa atggttcaaa ggagatcttg agttgaggcc2461 ctcaacattc ctcattattg accctctctt gggacttttg aagattcaag aaacacaaga2521 tctggatgct ggcgattata cctgtgtagc catcaatgag gctggaagag caactggcaa2581 gataactctg gatgttggct cacctccagt tttcatacaa gaacctgctg atgtgtctat2641 ggaaattggc tcaaatgtga cattaccttg ttatgttcag ggttatccag aaccaacaat2701 caaatggcga agattagaca acatgccaat tttctcaaga cctttttcag ttagttccat2761 cagccaacta agaacaggag ctctctttat tttaaactta tgggcaagtg ataaaggaac2821 ctatatttgt gaagctgaaa accagtttgg aaagatccag tcagagacaa cagtaacagt2881 gaccggactt gttgctccac ttattggaat cagcccttca gtggccaatg ttattgaagg2941 acagcagctt actttgccct gtactctgtt agctggaaat cccattccag aacgtcggtg3001 gattaagaat tcagctatgt tgctccaaaa tccttacatc actgtgcgca gtgatgggag3061 cctccatatt gaaagagttc agcttcagga tggtggtgaa tatacttgtg tggccagtaa3121 cgttgctggg accaataaca aaactacctc tgtggttgtg catgttctgc caaccattca3181 gcatgggcag cagatactca gtacaattga aggcattcca gtaactttac catgcaaagc3241 aagtggaaat cccaaaccgt ctgtcatctg gtccaagaaa ggagagctga tttcaaccag3301 cagtgctaag ttttcagcag gagctgatgg tagtctgtat gtggtatcac ctggaggaga3361 ggagagtggg gagtatgtct gcactgccac caatacagcc ggctacgcca aaaggaaagt3421 gcagctaaca gtctatgtaa ggcccagagt gtttggagat caacgaggac tgtcccagga3481 taagcctgtt gagatctccg tccttgcagg ggaagaggta acacttccat gtgaagtgaa3541 gagcttacct ccacccataa ttacttgggc caaagaaacc cagctcatct caccgttctc3601 tccaagacac acattcctcc cttctggttc aatgaagatc actgaaaccc gcacttcaga3661 tagtgggatg tatctttgtg ttgccacaaa tattgctggg aatgtgactc aggctgtcaa3721 attaaatgtc catgttcctc caaagataca gcgtggacct aaacatctca aagtccaagt3781 tggtcaaaga gtggatattc catgtaatgc tcaagggact cctcttcctg taatcacctg3841 gtccaaaggt ggaagcacta tgctggttga tggagagcac catgttagca atccagacgg3901 aactttaagc atcgaccaag ccacgccctc agatgctggc atatatacat gtgttgctac3961 taacatagca ggcactgatg aaacagagat aacgctacat gtccaagaac cacccacagt4021 ggaagatcta gaacctccat ataacactac tttccaagaa agagtggcca atcaacgcat4081 tgaatttcca tgtcctgcaa aaggtacccc taaaccaacc atcaaatggt tacacaatgg4141 tagagagttg acaggcagag agcctggcat ttctatcttg gaagatggca cattgctggt4201 tattgcttct gttacaccct atgacaatgg ggagtacatc tgtgtggcag tcaatgaagc4261 tggaaccaca gaaagaaaat ataacctcaa agtccatgtt cctccagtaa ttaaagataa4321 agaacaagtt acaaatgtgt cggtgttgtt aaatcagctg accaatctct tctgtgaagt4381 ggaaggcact ccatctccca tcattatgtg gtataaagat aatgtccagg tgactgaaag4441 cagcactatt cagactgtga acaatgggaa gatactgaag ctcttcagag ccactccaga4501 ggatgcagga agatattcct gcaaagcaat taatattgca ggcacttctc agaagtactt
4561 taacattgat gtgctagttc cacccaccat aataggtacc aacttcccaa atgaagtctc4621 agttgtcctc aaccgtgacg tcgcccttga atgccaggtc aaaggcactc cctttcctga4681 tattcattgg ttcaaagatg gcaagccttt atttttgggc gatcctaatg ttgaacttct4741 agacagagga caagtcttac atttaaagaa tgcacggaga aatgacaagg ggcgctacca4801 atgtactgtg tctaatgcag ctggcaaaca agccaaggat ataaaactga ctatctatat4861 tccacctagt attaaaggag gaaatgtcac cacagacata tcagtattga tcaacagcct4921 tattaaactg gaatgtgaaa cacggggact tccaatgcct gccattactt ggtataagga4981 cgggcagcca atcatgtcca gctcacaagc actttatatt gataaaggac aatatcttca5041 tattcctcga gcacaggtct ctgattcagc aacatatacg tgtcacgtag ccaatgttgc5101 tggaactgct gaaaaatcat tccatgtgga tgtctatgtt cctccaatga ttgaaggcaa5161 cttggccacg cctttgaata agcaagtagt tattgctcat tctctgacac tggagtgcaa5221 agctgctgga aacccttctc ccattctcac ctggttgaaa gatggtgtac ctgtgaaagc5281 taatgacaat atccgcatag aagctggtgg gaagaaactc gaaatcatga gtgcccaaga5341 aattgatcga ggacagtaca tatgcgtggc taccagtgtg gcaggagaaa aggaaatcaa5401 atatgaagtt gatgtcttgg tgccaccagc tatagaagga ggagatgaaa catcttactt5461 cattgtgatg gttaataact tactggagct agattgtcat gtgacaggct ctcccccacc5521 aactatcatg tggctgaagg atggccagtt aattgatgaa agggatggat tcaagatttt5581 attaaatgga cgcaaactgg ttattgctca ggctcaagtg tcaaacacag gcctttatcg5641 gtgcatggca gcaaatactg ctggagacca caagaaggaa tttgaagtga ctgttcatgt5701 tcctccaaca atcaagtcct caggcctttc tgagagagtt gtggtaaaat acaagcctgt5761 cgccttgcag tgcatagcca atgggattcc aaatccttcc attacatggt taaaagatga5821 ccagcctgtg aacactgccc aaggaaacct taaaatacag tcttctggtc gagttctaca5881 aattgccaaa accctgttgg aagatgctgg cagatacaca tgtgtggcta ccaacgcagc5941 tggagaaaca caacagcaca ttcaactgca tgttcatgaa ccacctagtc tggaagatgc6001 tggaaaaatg ctgaatgaga ctgtgttggt gagcaaccct gtacagctgg agtgtaaggc6061 agctggaaat cctgtgcctg ttattacatg gtacaaagat aatcgtctac tctcaggttc6121 caccagcatg actttcttga acagaggaca gatcattgat attgaaagtg cccagatctc6181 agatgctggc atatataaat gcgtggccat caactcagct ggagctacag agttatttta6241 cagtctgcaa gttcatgtgg ccccatcaat ttctggcagc aataacatgg tggcagtggt6301 ggttaataac ccggtgaggt tagaatgtga agccagaggt attcctgccc caagtctgac6361 ctggttgaaa gatgggagtc ctgtttctag tttttctaat ggattacagg ttctctctgg6421 tggtcgaatc ctagcattga ccagtgcaca aatcagcgac acaggaaggt acacctgcgt6481 ggcagtgaat gctgctggag aaaagcaaag ggacattgac ctccgagtat atgttccgcc6541 aaatattatg ggagaagaac agaatgtctc tgtcctcatt agccaagctg tggaattact6601 atgtcaaagt gatgctattc ccccacctac tcttacttgg ttaaaagacg gccacccctt6661 gctgaagaaa ccaggcctca gtatatctga aaatagaagt gtgttaaaga ttgaagatgc6721 tcaggttcaa gacactggtc gttacacttg tgaagcaaca aatgttgctg gaaaaactga6781 aaaaaaaaac tacaatgtca acatttgggt ccccccaaat attggtggtt ctgatgaact6841 tactcaactt acagtcattg aagggaatct cattagtctg ttgtgtgaat caagtggtat6901 tccaccccca aatctcatct ggaagaagaa aggctctcca gtgctgactg attccatggg6961 gcgagttaga attttatctg ggggcaggca attacaaatt tcaattgctg aaaagtctga7021 tgcagcactc tattcatgtg tggcgtcgaa tgttgctggg actgcaaaga aagaatacaa7081 tctgcaagtt tacattagac caaccataac caacagtggc agccacccta ctgaaattat7141 tgtgacccga gggaagagta tctccttgga gtgtgaggtg cagggtattc caccaccaac7201 agtgacctgg atgaaagatg gccacccctt gatcaaggca aagggagtag aaatactgga7261 tgaaggtcac atccttcagc tgaagaacat tcatgtatct gacacaggcc gttatgtgtg7321 tgttgctgtg aatgtagcag gaatgactga caaaaaatat gacttaagtg tccatgctcc7381 tccaagcatc ataggaaacc acaggtcacc tgaaaatatt agtgtggtag aaaagaactc
7441 agtatctttg acttgtgaag cttctggaat tcccctgcct tccataacct ggttcaaaga7501 tgggtggcct gtcagcctta gcaattctgt gaggattctt tcaggaggca ggatgctacg7561 gctgatgcag accacaatgg aagatgctgg ccaatatact tgcgttgtaa ggaatgcagc7621 tggtgaagaa agaaaaatct ttgggctttc agtattagta ccacctcata ttgtgggtga7681 aaatacattg gaagatgtga aggtaaaaga gaaacagagt gttacgctga cttgtgaagt7741 gacagggaat ccagtgccag aaattacatg gcacaaagat gggcagcccc tccaagaaga7801 tgaagcccat cacattatat ctggtggccg ttttcttcaa attaccaatg tccaggtgcc7861 acacactgga agatatacat gtttggcttc cagtccagct ggccacaaga gcaggagctt7921 cagtcttaat gtatttgtat ctcctacaat tgctggtgta ggtagtgatg gcaaccctga7981 agatgtcact gtcatcctta acagccctac atctttggtc tgtgaagctt attcatatcc8041 tccagctacc atcacctggt ttaaggatgg cactccttta gaatctaacc gaaatattcg8101 tattcttcca ggaggcagaa ctctgcagat cctcaatgca caggaggaca atgctggaag8161 atactcttgt gtagccacga atgaggctgg agaaatgata aagcactatg aagtgaaggt8221 gtacattcca cccataatca ataaagggga cctttggggg ccaggtcttt cccctaaaga8281 agtgaagatc aaagtaaaca acactctgac cttggaatgt gaagcgtatg caattccttc8341 tgcctccctc agctggtaca aggatggaca gccccttaaa tccgatgatc atgttaatat8401 tgctgcgaat ggacacacac ttcaaataaa ggaggctcaa atatcagaca ccggacgata8461 tacttgtgta gcatctaaca ttgcaggtga agatgagttg gattttgatg tgaatattca8521 agttcctcca agttttcaga aactctggga aataggaaac atgctagata ctggcaggaa8581 tggtgaagcc aaagatgtga tcatcaacaa tcccatttct ctttactgtg agacaaatgc8641 tgctccccct cctacactga catggtacaa agatggccac cctctgacct caagtgataa8701 agtattgatt ttgccaggag ggcgagtgtt gcagattcct cgggctaaag tagaagatgc8761 tgggagatac acatgtgtgg ctgtgaatga ggctggagaa gattcccttc aatatgatgt8821 ccgtgtactc gtgccgccaa ttatcaaggg agcaaatagt gatctccctg aagaggtcac8881 cgtgctggtg aacaagagtg cactgataga gtgtttatcc agtggcagcc cagcaccaag8941 gaattcctgg cagaaagatg gacagccctt gctagaagat gaccatcata aatttctatc9001 taatggacga attctgcaga ttctgaatac tcaaataaca gatatcggca ggtatgtgtg9061 tgttgctgag aacacagctg ggagtgccaa aaaatatttt aacctcaatg ttcatgttcc9121 tccaagtgtc attggtccta aatctgaaaa tcttaccgtc gtggtgaaca atttcatctc9181 tttgacctgt gaggtctctg gttttccacc tcctgacctc agctggctca agaatgaaca9241 gcccatcaaa ctgaacacaa atactctcat tgtgcctggt ggtcgaactc tacagattat9301 tcgggccaag gtatcagatg gtggtgaata cacttgtata gctatcaatc aagctggcga9361 aagcaagaaa aagttttccc tgactgttta tgtgccccca agcattaaag accatgacag9421 tgaatctctt tctgtagtta atgtaagaga gggaacttct gtgtctttgg agtgtgagtc9481 gaacgctgtg ccacctccag tcatcacttg gtataagaat gggcggatga taacagagtc9541 tactcatgtg gagattttag ctgatggaca aatgctacac attaagaaag ctgaggtatc9601 tgacacaggc cagtatgtat gtagagctat aaatgtagca ggacgggatg ataaaaattt9661 ccacctcaat gtatatgtgc cacccagtat tgaaggacct gaaagagaag tgattgtgga9721 gacgatcagc aatcctgtga cattaacatg tgatgccact gggatcccac ctcccacgat9781 agcatggtta aagaaccaca agcgcataga aaattctgac tcactggaag ttcgtatttt9841 gtctggaggt agcaaactcc agattgcccg gtctcagcat tcagatagtg gaaactatac9901 atgtattgct tcaaatatgg agggaaaagc ccagaaatat tactttcttt caattcaagt9961 tcctccaagt gttgctggtg ctgaaattcc aagtgatgtc agtgtccttc taggagaaaa10021 tgttgagctg gtctgcaatg caaatggcat tcctactcca cttattcaat ggcttaaaga10081 tggaaagccc atagctagtg gtgaaacaga aagaatccga gtgagtgcaa atggcagcac10141 attaaacatt tatggagctc ttacatctga cacggggaaa tacacatgtg ttgctactaa10201 tcccgctgga gaagaagacc gaatttttaa cttgaatgtc tatgttacac ctacaattag10261 gggtaataaa gatgaagcag agaaactaat gactttagtg gatacttcaa taaatattga
10321 atgcagagcc acagggacgc ctccaccaca gataaactgg ctgaagaatg gacttcctct10381 gcctctctcc tcccatatcc ggttactggc agcaggacaa gttatcagga ttgtgagagc10441 tcaggtgtct gatgtcgctg tgtatacttg tgtggcctcc aacagagctg gggtggataa10501 taagcattac aatcttcaag tgtttgcacc accaaatatg gacaattcaa tggggacaga10561 ggaaatcaca gttctcaaag gtagttccac ctctatggca tgcattactg atggaacccc10621 agctcccagt atggcctggc ttagagatgg ccagcctctg gggcttgatg cccatctgac10681 agtcagcacc catggaatgg tcctgcagct cctcaaagca gagactgaag attcgggaaa10741 gtacacctgc attgcctcaa atgaagctgg agaagtcagc aagcacttta tcctcaaggt10801 cctagaacca cctcacatta atggatctga agaacatgaa gagatatcag taattgttaa10861 taacccactt gaacttacct gcattgcttc tggaatccca gcccctaaaa tgacctggat10921 gaaagatggc cggccccttc cacagacgga tcaagtgcaa actctaggag gaggagaggt10981 tcttcgaatt tctactgctc aggtggagga tacaggaaga tatacatgtc tggcatccag11041 tcctgcagga gatgatgata aggaatatct agtgagagtg catgtacctc ctaatattgc11101 tggaactgat gagccccggg atatcactgt gttacggaac agacaagtga cattggaatg11161 caagtcagat gcagtgcccc cacctgtaat tacttggctc agaaatggag aacggttaca11221 ggcaacacct cgagtgcgaa tcctatctgg agggagatac ttgcaaatca acaatgctga11281 cctaggtgat acagccaatt atacctgtgt tgccagcaac attgcaggaa agactacaag11341 agaatttatt ctcactgtaa atgttcctcc aaacataaag gggggccccc agagccttgt11401 aattctttta aataagtcaa ctgtattgga atgcatcgct gaaggtgtgc caactccaag11461 gataacatgg agaaaggatg gagctgttct agctgggaat catgcaagat attccatctt11521 ggaaaatgga ttccttcata ttcaatcagc acatgtcact gacactggac ggtatttgtg11581 tatggccacc aatgctgctg gaacagatcg caggcgaata gatttacagg tccatgttcc11641 tccatctatt gctccgggtc ctaccaacat gactgtaata gtaaatgttc aaactactct11701 ggcttgtgag gctactggga taccaaaacc atcaatcaat tggagaaaaa atgggcatct11761 tcttaatgtg gatcaaaatc agaactcata caggctcctt tcttcaggtt cactagtaat11821 tatttcccct tctgtggatg acactgcaac ctatgaatgt actgtgacaa acggtgctgg11881 agatgataaa agaactgtgg atctcactgt ccaagttcca ccttccatag ctgatgagcc11941 tacagatttc ctagtaacca aacatgcccc agcagtaatt acctgcactg cttcgggagt12001 tccatttccc tcaattcact ggaccaaaaa tggtataaga ctgcttccca ggggagatgg12061 ctatagaatt ctgtcctcag gagcaattga aatacttgcc acccaattaa accatgctgg12121 aagatacact tgtgtcgcta ggaatgcggc tggctctgca catcgacacg tgacccttca12181 tgttcatgag cctccagtca ttcagcccca accaagtgaa ctacacgtca ttctgaacaa12241 tcctatttta ttaccatgtg aagcaacagg gacacccagt cctttcatta cttggcaaaa12301 agaaggcatc aatgttaaca cttcaggcag aaaccatgca gttcttccta gtggcggctt12361 acagatctcc agagctgtcc gagaggatgc tggcacttac atgtgtgtgg cccagaaccc12421 ggctggtaca gccttgggca aaatcaagtt aaatgtccaa gttcctccag tcattagccc12481 tcatctaaag gaatatgtta ttgctgtgga caagcccatc acgttatcct gtgaagcaga12541 tggcctccct ccgcctgaca ttacatggca taaagatggg cgtgcaattg tggaatctat12601 ccgccagcgc gtcctcagct ctggctctct gcaaatagca tttgtccagc ctggtgatgc12661 tggccattac acgtgcatgg cagccaatgt agcaggatca agcagcacaa gcaccaagct12721 caccgtccat gtaccaccca ggatcagaag tacagaagga cactacacgg tcaatgagaa12781 ttcacaagcc attcttccat gcgtagctga tggaatcccc acaccagcaa ttaactggaa12841 aaaagacaat gttcttttag ctaacttgtt aggaaaatac actgctgaac catatggaga12901 actcatttta gaaaatgttg tgctggagga ttctggcttc tatacctgtg ttgctaacaa12961 tgctgcaggt gaagatacac acactgtcag cctgactgtg catgttctcc ccacttttac13021 tgaacttcct ggagacgtgt cattaaataa aggagaacag ctacgattaa gctgtaaagc13081 tactggtatt ccattgccca aattaacatg gaccttcaat aacaatatta ttccagccca13141 ctttgacagt gtgaatggac acagtgaact tgttattgaa agagtgtcaa aagaggattc
13201 aggtacttat gtgtgcaccg cagagaacag cgttggcttt gtgaaggcaa ttggatttgt13261 ttatgtgaaa gaacctccag tcttcaaagg tgattatcct tctaactgga ttgaaccact13321 tggtgggaat gcaatcctga attgtgaggt gaaaggagac cccaccccaa ccatccagtg13381 gaacagaaag ggagtggata ttgaaattag ccacagaatc cggcaactgg gcaatggctc13441 cctggccatc tatggcactg ttaatgaaga tgccggtgac tatacatgtg tagctaccaa13501 tgaagctggg gtggtggagc gcagcatgag tctgactctg caaagtcctc ctattatcac13561 tcttgagcca gtggaaactg ttattaatgc tggtggcaaa atcatattga attgtcaggc13621 aactggagag cctcaaccaa ccattacatg gtcccgtcaa gggcactcta tttcctggga13681 tgaccgggtt aacgtgttgt ccaacaactc attatatatt gctgatgctc agaaagaaga13741 tacctctgaa tttgaatgtg ttgctcgaaa cttaatgggt tctgtccttg tcagagtgcc13801 agtcatagtc caggttcatg gtggattttc ccagtggtct gcatggagag cctgcagtgt13861 cacctgtgga aaaggcatcc aaaagaggag tcgtctgtgc aaccagcccc ttccagccaa13921 tggtgggaag ccctgccaag gttcagattt ggaaatgcga aactgtcaaa ataagccttg13981 tccagtggat ggtagctggt cggaatggag tctttgggaa gaatgcacaa ggagctgtgg14041 acgcggcaac caaaccagga ccaggacttg caataatcca tcagttcagc atggtgggcg14101 gccatgtgaa gggaatgctg tggaaataat tatgtgcaac attaggcctt gcccagttca14161 tggagcatgg agcgcttggc agccttgggg aacatgcagc gaaagttgtg ggaaaggtac14221 tcagacaaga gcaagacttt gtaataaccc accaccagcg tttggtgggt cctactgtga14281 tggagcagaa acacagatgc aagtttgcaa tgaaagaaat tgtccaattc atggcaagtg14341 ggcgacttgg gccagttgga gtgcctgttc tgtgtcatgt ggaggaggtg ccagacagag14401 aacaaggggc tgctccgacc ctgtgcccca gtatggagga aggaaatgcg aagggagtga14461 tgtccagagt gatttttgca acagtgaccc ttgcccaacc catggtaact ggagtccttg14521 gagtggctgg ggaacatgca gccggacgtg taacggaggg cagatgcggc ggtaccgcac14581 atgtgataac cctcctccct ccaatggggg aagagcttgt gggggaccag actcccagat14641 ccagaggtgc aacactgaca tgtgtcctgt ggatggaagt tggggaagct ggcatagttg14701 gagccagtgc tctgcctcct gtggaggagg tgaaaagact cggaagcggc tgtgcgacca14761 tcctgtgcca gttaaaggtg gccgtccctg tcccggagac actactcagg tgaccaggtg14821 caatgtacaa gcatgtccag gtgggcccca gcgagccaga ggaagtgtta ttggaaatat14881 taatgatgtt gaatttggaa ttgctttcct taatgccaca ataactgata gccctaactc14941 tgatactaga ataatacgtg ccaaaattac caatgtacct cgtagtcttg gttcagcaat15001 gagaaagata gtttctattc taaatcccat ttattggaca acagcaaagg aaataggaga15061 agcagtcaat ggctttaccc tcaccaatgc agtcttcaaa agagaaactc aagtggaatt15121 tgcaactgga gaaatcttgc agatgagtca tattgcccgg ggcttggatt ccgatggttc15181 tttgctgcta gatatcgttg tgagtggcta tgtcctacag cttcagtcac ctgctgaagt15241 cactgtaaag gattacacag aggactacat tcaaacaggt cctgggcagc tgtacgccta15301 ctcaacccgg ctgttcacca ttgatggcat cagcatccca tacacatgga accacaccgt15361 tttctatgat caggcacagg gaagaatgcc tttcttggtt gaaacacttc atgcatcctc15421 tgtggaatct gactataacc agatagaaga gacactgggt tttaaaattc atgcttcaat15481 atccaaagga gatcgcagta atcagtgccc ctccgggttt accttagact cagttggacc15541 tttttgtgct gatgaggatg aatgtgcagc agggaatccc tgctcccata gctgccacaa15601 tgccatgggg acttactact gctcctgccc taaaggcctc accatagctg cagatggaag15661 aacttgtcaa gatattgatg agtgtgcttt gggtaggcat acctgccacg ctggtcagga15721 ctgtgacaat acgattggat cttatcgctg tgtggtccgt tgtggaagtg gctttcgaag15781 aacctctgat gggctgagtt gtcaagatat taatgaatgt caagaatcca gcccctgtca15841 ccagcgctgt ttcaatgcca taggaagttt ccattgtgga tgtgaacctg ggtatcagct15901 caaaggcaga aaatgcatgg atgtgaacga gtgtagacaa aatgtatgca gaccagatca15961 gcactgtaag aacacccgtg gtggctataa gtgcattgat ctttgtccaa atggaatgac16021 caaggcagaa aatggaacct gtattgatat tgatgaatgt aaagatggga cccatcagtg
16081 cagatataac cagatatgtg agaatacaag aggcagctat cgttgtgtat gcccaagagg16141 ttatcggtct caaggagttg gaagaccctg catggacatt aatgaatgtg aacaagtgcc16201 taaaccttgt gcacatcagt gctccaacac ccccggcagc ttcaagtgta tctgtccacc16261 aggacaacat ttattagggg acgggaaatc ttgcgctgga ttggagaggc tgccaaatta16321 tggcactcaa tacagtagct ataaccttgc acggttctcc cctgtgagaa acaactatca16381 acctcaacag cattacagac agtactcaca tctctacagc tcctactcag agtatagaaa16441 cagcagaaca tctctctcca ggactagaag gactattagg aaaacttgcc ctgaaggctc16501 tgaggcaagc catgacacat gtgtagatat tgatgaatgt gaaaatacag atgcctgcca16561 gcatgagtgt aagaatacct ttggaagtta tcagtgcatc tgcccacgtg gctatcaact16621 cacacacaat ggaaagacat gccaagatat cgatgaatgt ctggagcaga atgtgcactg16681 tggacccaat cgcatgtgct tcaacatgag aggaagctac cagtgcatcg atacaccctg16741 tccacccaac taccaacggg atcctgtttc agggttctgc ctcaagaact gtccacccaa16801 tgatttggaa tgtgccttga gcccatatgc cttggaatac aaactcgtct ccctcccatt16861 tggaatagcc accaatcaag atttaatccg gctggttgca tacacagagg atggagtgat16921 gcatcccagg acaactttcc tcatggtaga tgaggaacag actgttcctt ttgccttgag16981 ggatgaaaac ctgaaaggag tggtgtatac aacacgacca ctacgagaag cagagaccta17041 ccgcatgagg gtccgagcct catcctacag tgccaatggg accattgaat atcagaccac17101 attcatagtt tatatagctg tgtccgccta tccatactaa ggaactctcc aaagcctatt17161 ccacatattt aaaccgcatt aatcatggca atcaagcccc cttccagatt actgtctctt17221 gaacagttgc aatcttggca gcttgaaaat ggtgctacac tctgttttgt gtgccttcct17281 tggtacttct gaggtatttt catgatccca ccatggtcat atcttgaagt atggtctaga17341 aaagtccctt attattttat ttattacact ggagcagtta cttcccaaag attattctga17401 acatctaaca ggacatatca gtgatggttt acagtagtgt agtacctaag atcattttcc17461 tgaaagccaa accaaacaac gaaaaacaag aacaactaat tcagaatcaa atagagtttt17521 tgagcatttg actattttta gaatcataaa attagttact aagtattttg atcaaagctt17581 ataaaataac ttacggagat ttttgtaagt attgatacat tataatagga cttgcctatt17641 ttcattttta agaagaaaaa caccactcat tttataaaat atagtacagc tactataagg17701 cttgtttgat cccaaatggt gcttatcttg attgaacatt cagaacaagg atattatttt17761 cagtgatttt gtgagatcag ctgaaccact tatgataata ataataaaaa agactacttt17821 gccctcacgt cagttgtaca tggcatggaa ctttaaaaat tttaatataa actttcatcc17881 agttagcttc ataactttta cgttccagaa ttttgtttat tttcctgtca atgaaagcaa17941 tttttaaaga taccagtggg acaggtttgg ttttttaaaa atctcatgtg ttcaaattaa18001 cataaatatt acacgtcaat acactgtaca tggtggtaat agactctaag caattgccaa18061 gatgtattct atttttatga agtgtatata tattacctta gtgtgcattt tctatataat18121 atcttgatgg actcttttat aaaattattt tataaaaaac aatgttacac taaaatcagc18181 ctaaataaat tttcacaact ttttttcat<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>127<211>3033<212>DNA<213>人類(Homo sapiens)<400>1271 gagtgtgtga cccagccctt cccccgtggc caagcagaga gagtggcctt gaggaagcca61 tagcagcagg agcagcatgg cctctgctgc ctctgtgacc agcctggcag atgaagtcaa121 ctgccccatc tgtcagggta ccctgaggga gccggtcact atcgactgcg gccacaactt
181 ctgccgggcc tgccttaccc gctactgtga gataccaggc ccagacctgg aggagtcccc241 tacttgccca ctctgcaaag aacccttccg tcctgggagc ttccggccca actggcagct301 ggctaacgtg gtggagaaca ttgagcgcct ccagctggtg tccacactgg gtttgggaga361 ggaggatgtc tgccaagagc acggagggaa gatctacttc ttctgtgagg atgatgagat421 gcagttgtgc gtggtgtgcc gggaggctgg ggagcacgct acccacacca tgcgcttcct481 ggaggatgca gcggctccct atagggaaca aatccataag tgtcttaaat gtctaagaaa541 agagagagag gagattcaag aaatccagtc aagaaaaaat aaaaggatgc aagtcctcct601 gactcaggtg tccaccaaga gacaacaggt gatttctgag ttcgcacacc tgaggaagtt661 tctagaggaa cagcagagca tcctcttagc acaattggag agccaggatg gggacatctt721 gaggcaacgg gatgaatttg atttgctggt tgctggggag atctgccggt ttagtgctct781 tattgaagaa ctggaggaga agaatgagag gccagcaagg gagctcctga cggacatcag841 aagcactcta ataagatgtg aaaccagaaa gtgccggaaa ccggtggctg tgtcgccaga901 gctgggccag aggattcggg actttcccca gcaggccctc ccgctgcaga gggagatgaa961 gatgtttctg gaaaaactat gctttgagtt ggactatgag ccagctcaca tttctctaga1021 ccctcagact tcccacccca agctcctctt gtccgaggac caccagcgag ctcagttctc1081 ctacaaatgg cagaactcac cagacaaccc ccagcgtttt gaccgggcca cctgtgttct1141 ggcccacact ggcatcacag gggggagaca cacgtgggtg tggatggcca gggtacctgg1201 ggactcaggc ggctgccagt tctgctcacc accatccgtg cttggcacag aagtagctgc1261 atagaaagag cactggattt gaagtcagaa gacctgggtt cttgaaccag cctgtcaacc1321 agttgtatga ctttaaacaa ggcatctcac ctcttttca tcttgttttct tccaataatg1381 ttagagttca tgtaatcaca ttctctagaa ccatttagtt tgtgttaact atgaaccaag1441 cagtgtggtg gccactggtg acttgaaaat atagagaaaa aaaaaacctg ctctatatct1501 gaaagagctc ttgggaagac agagaaacat aaagaggaaa ttacagcaca gtgtggtggg1561 tgttacggga agtccaaccc cagcattatg ggagttcagg ggaaggggca tagcccagcc1621 tggaaggaga gggtgagtgg gggatggctt tctgaaaagg gtggtctaaa ggatgcctat1681 ggtcaatagg gaaaagaggg gaagaagcat cttaagaaga ggaaacagca gagaactggc1741 tggatgacct gtgactctgg agcactgggt tgtctccatt gtcattatgg gcagatgtgt1801 gccatcccca gccgacgcca ctcactgcct ccttcctcct ggtgttgcca cttctgggtg1861 agattaaggt gcagggcctg ggggcaggag gacataaggt atagccataa atcataaccc1921 agggaccaca ctcaacccta gggaaattgt cttcctgatc agttgattac catctgaggt1981 caagaaatga gatagtggga gcaaatgggt cacaaatagc tcagctgtgg gctcagaaac2041 tgctaggtaa aagaattcca gaaggaggcc agggcataag ttggatgacc tatgaacttt2101 agtctaaaga attgagacta ccgtaattga gactactgta gtgacatctg agaaatggga2161 tggaagagtg accatgtttt attttcttgt tcttgtcact attgtatttt attttgcata2221 atcatgccct tcactgacag tctccttaac atcatctgtt tactctgctc agtgtaaact2281 acaatgctct gtcatctccc tactgggtct cctgggagga ggggagccat ccagggtgca2341 aactcaaagg cagagggcac agcgtgctta ggcccaagct tagaattcaa ttgagaagtt2401 ctgttgttca tccttacctc agcaggtaga aaagaggtgg agatcagaag ccagggatta2461 gagattgaat tgctttccct gggagtgtgc agtatctcat taaaatgttg tatattcaaa2521 aaaatacaga cacacacaag tgcctatata atgataaaac atatccaaag cacccaaacc2581 tgtgattcca gaaaagtaga tcctattttt gtttattttt attggcttta gctgtgtctt2641 ttgaaaggac tattatcctc taaaatgtat gtgtatgaag atcctggctt gcagctcggg2701 agctttacac accttgtgtc actttatctt ggtaacgagc caagatcatg caaccagttc2761 atccatgtct gacccaagag ctcttaactg ctatgctgca ctgcctcatt cagagataga2821 tgcctgcatg ggtcctggcg attattttaa tgctggctac acccccacag gtgacttgga2881 ttcagaaata caatttatat ttcttctttt taaattgttt tattttattt ttcttttaat2941 agttatatgt cagtgagaac aatttatatg tcttacactg agaaataaaa ctgctcataa3001 gtgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>128<211>3346<212>DNA<213>人類(Homo sapiens)<400>1281 aaccacgatg tctttggcac agcctctcat ctgtcagatg ggagcgggga ccccggagag61 ggagtcagcc gaggtcctgg cattccttgt gaacccccgt ctgtgggttt ctggtccagt121 gtcccttctc cagattagat ggcttaggcc tcctctaagg gggtgggcgt gcacatccgg181 agagctgtct ggtgtgcagg actgggctgc aggttaccct gaactgcaac catcttagag241 caaggcccag cttgcagcag gaggagctgc aggccgccca ccctagccac ggcccctgcc301 ctggcaggaa gcttccaaga gtaaacactg cctaatcgtc ccgcccagta gtgagcaggc361 ctgtcccatt ccatactgac cagattccca gtcaccaagg ccccctctca ctccgctcca421 ctcctcgggc tggctctcct gaggatgcac cagcgtcacc cccgggcaag atgccctccc481 ctctgtgtgg ccggaatcct tgcctgtggc tttctcctgg gctgctgggg accctcccat541 ttccagcaga gttgtcttca ggctttggag ccacaggccg tgtcttctta cttgagccct601 ggtgctccct taaaaggccg ccctccttcc cctggcttcc agaggcagag gcagaggcag661 aggcgggctg caggcggcat cctacacctg gagctgctgg tggccgtggg ccccgatgtc721 ttccaggctc accaggagga cacagagcgc tatgtgctca ccaacctcaa catcggggca781 gaactgcttc gggacccgtc cctgggggct cagtttcggg tgcacctggt gaagatggtc841 attctgacag agcctgaggg tgccccaaat atcacagcca acctcacctc gtccctgctg901 agcgtctgtg ggtggagcca gaccatcaac cctgaggacg acacggatcc tggccatgct961 gacctggtcc tctatatcac taggtttgac ctggagttgc ctgatggtaa ccggcaggtg1021 cggggcgtca cccagctggg cggtgcctgc tccccaacct ggagctgcct cattaccgag1081 gacactggct tcgacctggg agtcaccatt gcccatgaga ttgggcacag cttcggcctg1141 gagcacgacg gcgcgcccgg cagcggctgc ggccccagcg gacacgtgat ggcttcggac1201 ggcgccgcgc cccgcgccgg cctcgcctgg tccccctgca gccgccggca gctgctgagc1261 ctgctcagac ccgtccctcc gtcgccgctc cctctgctgg ccacccacct ctgcgccggc1321 aggagcctta gtcttggtcc cagccaagag ccggctcctg gtggggggcg cgggccgaga1381 actcctgttc ccactcacaa aaggccacgc ttccaaacgc ttccatcctc gtgcccactc1441 ctccgtcccg cctcctcccg gtgtacaccc cgggactgag ccgggcctga gccgggcctt1501 gtcgcagcgc aggacgggcg cgctgcgtgt gggacccgcc gcggcctcaa cccgggtccg1561 cggggcaccc gccggatgcg cagcctggcc tctactacag cgccaacgag cagtgccgcg1621 tggccttcgg ccccaaggct gtcgcctgca ccttcgccag ggagcacctg gtgagtctgc1681 cggcggtggc ctgggattgg ctgtgaggtc cctccgcatc acccagctca cgtcccccaa1741 aacgtgcatg gatatgtgcc aggccctctc ctgccacaca gacccgctgg accaaagcag1801 ctgcagccgc ctcctcgttc ctctcctgga tgggacagaa tgtggcgtgg agaagtggtg1861 ctccaagggt cgctgccgct ccctggtgga gctgaccccc atagcagcag tgcatgggcg1921 ctggtctagc tggggtcccc gaagtccttg ctcccgctcc tgcggaggag gtgtggtcac1981 caggaggcgg cagtgcaaca accccagacc tgcctttggg gggcgtgcat gtgttggtgc2041 tgacctccag gccgagatgt gcaacactca ggcctgcgag aagacccagc tggagttcat2101 gtcgcaacag tgcgccagga ccgacggcca gccgctgcgc tcctcccctg gcggcgcctc2161 cttctaccac tggggtgctg ctgtaccaca cagccaaggg gatgctctgt gcagacacat2221 gtgccgggcc attggcgaga gcttcatcat gaagcgtgga gacagcttcc tcgatgggac2281 ccggtgtatg ccaagtggcc cccgggagga cgggaccctg agcctgtgtg tgtcgggcag
2341 ctgcaggaca tttggctgtg atggtaggat ggactcccag caggtatgggacaggtgcca2401 ggtgtgtggt ggggacaaca gcacgtgcag cccacggaag ggctctttca cagctggcag2461 agcgagagaa tatgtcacat ttctgacagt tacccccaac ctgaccagtg tctacattgc2521 caaccacagg cctctcttca cacacttggc ggtgaggatc ggagggcgct atgtcgtggc2581 tgggaagatg agcatctccc ctaacaccac ctacccctcc ctcctggagg atggtcgtgt2641 cgagtacaga gtggccctca ccgaggaccg gctgccccgc ctggaggaga tccgcatctg2701 gggacccctc caggaagatg ctgacatcca ggtgggaggt gtcagagccc agctcatgca2761 catcagctgg tggagcaggc ctggccttgg agaacgagac ctgtgtgcca ggggcagatg2821 gcctggaggc tccagtgact gaggggcctg gctccgtaga tgagaagctg cctgcccctg2881 agccctgtgt cgggatgtca tgtcctccag gctggggcca tctggatgcc acctctgcag2941 gggagaaggc tccctcccca tggggcagca tcaggacggg ggctcaagct gcacacgtgt3001 ggagccctgc ggcagggtcg tgctccgtct cctgcgggcg aggtctgatg gagctgcgtt3061 tcctgtgcat ggactctgcc ctcagggtgc ctgtccagga agagctgtgt ggcctggcaa3121 gcaagcctgg gagccggcgg gaggtctgcc aggctgtccc gtgccctgct cggtggcagt3181 acaagctggc ggcctgcagc gtgagctgtg ggagaggggt cgtgcggagg atcctgtatt3241 gtgcccgggc ccatggggag gacgatggtg aggagatcct gttggagacc cagtgccagg3301 ggctgcctcg cccggaaccc caggaggcct gcagcctgga gccctg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>129<211>5115<212>DNA<213>人類(Homo sapiens)<400>1291 ccagccatgg gctcggggcg cgtacccggg ctctgcctgc ttgtcctgct ggtccacgcc61 cgcgccgccc agtacagcaa agccgcgcaa gatgtggatg agtgtgtgga ggggactgac121 aactgccaca tcgatgctat ctgccagaac agcccgaggt catacaagtg catctgcaag181 tctggctaca caggggacgg caaacactgc aaagacgtgg atgagtgcga gcgagaggat241 aatgcaggtt gtgtgcatga ctgtgtcaac atccctggca attaccggtg tacctgctat301 gatggattcc acctggcaca tgacggacac aactgtctgg atgtggacga gtgtgccgag361 ggcaacggcg gctgtcagca gagctgtgtc aacatgatgg gcagctatga gtgccactgc421 cgggaaggct tcttcctcag cgacaaccag catacctgta tccagcggcc agaagaagga481 atgaattgca tgaacaagaa ccacggctgt gcccacattt gccgggagac acccaagggg541 ggtattgcct gtgaatgccg tcctggcttt gagcttacca agaaccaacg ggactgtaaa601 ttgacatgca actatggtaa cggcggctgc cagcacacgt gtgatgagac agagcagggt661 ccccggtgcg gctgccatat caagtttgtg ctccataccg acgggaagac atgcatcgag721 acctgtgctg tcaacaacgg gggctgtgac agtaagtgcc atgatgcagc gactggtgtc781 cactgcacct gccctgtggg cttcatgctg cagccagaca ggaagacgtg caaagatata841 gatgagtgcc gcttaaacaa cgggggctgt gaggatattt gccgcaacac agtgggcagc901 ttcgaatgca gttgcaagaa aggctataag cttctcatca atgagaggaa ctgccaggat961 atagacgagt gttcctttga tcgaacctgt gaccacatat gtgtcaacac accgggaagc1021 ttccagtgtc tctgccatcg tggctacctg ttgtatggta tcacccattg tggggatgtg1081 gatgaatgca gcatcaaccg gggaggttgc cgctttggct gcatcaagac tcctggcagc1141 taccagtgta cctgcccagc aggccagggt cggctgcact ggaatggcaa agattgcaca1201 gagccactga agtgtcaggg cagtcctggg gcctcgaaag ccatgctcag ctgcaaccgg1261 tctggcaaga aggacacctg tgccctgacc tgtccctcca gggcccgatt tttgccagag
1321 tctgagaatg gcttcacggt gagctgtggg acccccagcc ccagggctgc tccagcccga1381 gctggccaca atgggaacag caccaactcc aaccactgcc atgaggctgc agtgctgtcc1441 attaaacaac gggcctcctt caagatcaag gatgccaaat gccgtttgca cctgcgaaac1501 aaaggcaaaa cagaggaggc tggcagaatc acagggccag gtggtgcccc ctgctctgaa1561 tgccaggtca ccttcatcca ccttaagtgt gactcctctc ggaagggcaa gggccgacgg1621 gcccggaccc ctccaggcaa agaggtcaca aggctcaccc tggaactgga ggcagaggtc1681 agagccgaag aaaccacagc cagctgtggg ctgccctgcc tccgacagcg aatggaacgg1741 cggctgaaag gatccctgaa gatgctcaga aagtccatca accaggaccg cttcctgctg1801 cgcctggcag gccttgatta tgagctggcc cacaagccgg gcctggtagc cggggagcga1861 gcagagccga tggagtcctg taggcccggg cagcaccgtg ctgggaccaa gtgtgtcagc1921 tgcccgcagg gaacgtatta ccacggccag acggagcagt gtgtgccatg cccagcgggc1981 accttccagg agagagaagg gcagctctcc tgcgaccttt gccctgggag tgatgcccac2041 gggcctcttg gagccaccaa cgtcaccacg tgtgcaggtc agtgcccacc tggccaacac2101 tctgtagatg ggttcaagcc ctgtcagcca tgcccacgtg gcacctacca acctgaagca2161 ggacggaccc tatgcttccc ttgtggtggg ggcctcacca ccaagcatga aggggccatt2221 tccttccaag actgtgacac caaagtccag tgctccccag ggcactacta caacaccagc2281 atccaccgct gtattcgctg tgccatgggc tcctatcagc ccgacttccg tcagaacttc2341 tgcagccgct gtccaggaaa cacaagcaca gactttgatg gctctaccag tgtggcccaa2401 tgcaagaatc gtcagtgtgg tggggagctg ggtgagttca ctggctatat tgagtccccc2461 aactacccgg gcaactaccc agctggtgtg gagtgcatct ggaacatcaa ccccccaccc2521 aagcgcaaga tccttatcgt ggtaccagag atcttcctgc catctgagga tgagtgtggg2581 gacgtcctgg tcatgagaaa gaactcatcc ccatcctcca ttaccactta tgagacctgc2641 cagacctacg agcgtcccat tgccttcact gcccgttcca ggaagctctg gatcaacttc2701 aagacaagcg aggccaacag cgcccgtggc ttccagattc cctatgttac ctatgatgag2761 gactatgagc agctggtaga agacattgtg cgagatggcc ggctctatgc ctctgaaaac2821 caccaggaga ttttaaagga caagaagctc atcaaggcct tctttgaggt gctagcccac2881 ccccagaact acttcaagta cacagagaaa cacaaggaga tgctgccaaa atccttcatc2941 aagctgctcc gctccaaagt ttccagcttc ctgaggccct acaaatagta accctaggct3001 cagagaccca attttttaag cccccagact ccttagccct cagagccggc agccccctac3061 cctcagacaa ggaactctct cctctctttt tggagggaaa aaaaaaatat cactacacaa3121 accaggcact ctccctttct gtctttctag tttcctttcc ttgtctctct ctgcctgcct3181 ctctactgtt cccccttttc taacacacta cctagaaaag ccattcagta ctggctctag3241 tccccgtgag atgtaaagaa acagtacagc cccttccact gcccatttta ccagctcaca3301 ttcccgaccc catcagcttg gaagggtgct agaggcccat caaggaagtg ggtctggtgg3361 gaaacgggga ggggaaagaa gggcttctgc cattataggg ttgtgccttg ctagtcaggg3421 gccaaaatgt cccctggctc tgctccctag ggtgattcta acagcccagg gtcctgccaa3481 agaagccttt gatttacagg cttaatgcca gcaccagtcc tctggggcac atggtttgag3541 ctctggactt cccacatggc cagctttctt gtctatacag atcctctctt tctttcccta3601 cgtctgcctg gggtctactc cataagggtt tacaaatggc ccacaacact gagttagtgg3661 acaccggcta aatgaggaag agcagcaggc attgtcatgg tgaatgcccc gctgtagctc3721 cctgagagaa agactgtaac tctgcaggac agaaacaagg ttttaaagca ttgccaaaaa3781 aaagaaaaca gaaagaaaaa atgtatcatc taaaggacta gacacagaac aattggaagt3841 caacttcaaa cactaatccc ttttcttgtc ttccctggcc cagccacctc ctcagcccca3901 tgtgatgctc cctgggggag ccctactccc cttgctacat gttgtcctta aacatggtta3961 ttgacctgaa gccagcctag gccttgccct acagttgttt ttcccttgta gccccagctg4021 gcttgtgggc ttcaccaaag aggaccccac tctgaagcca gcctggagcc acctacctct4081 ggcctcaggc tgtgggcagc aaaaggaatg tgtgtgcact tggcgagcct cctgcccacc4141 ctgtccacac ctaataagtg caatcatttt gagtctttct atgttgtcta gacggagggg
4201 tttttgtttt ctgggtttgt tttttgtttt tgtttcttct tcctctatta gcaaaaccct4261 atttatagct gcccaagaga aaagagtgta tgtttggagt ggaagaaaat cggttttgaa4321 tctcatgaac cttgagtgct ggagcatctg atctgtctct atgccaccac tggccaccta4381 gagcccttgg ctgtggtaat ccagggtaat tgcgcagagg catctgatgt gtaggaaagt4441 aattctgggg atttgatgga gcagaaagga gagagaccta tgtttgctaa accaatcttg4501 ctatccctat gcctctccat ggagtcagtg tggacctcat gattatagag gccaatggaa4561 ctggtcagtg attctctacc ccaagtaggg aaaacctcca tcttttccct gtcttcatcc4621 tgttatcccc tggtgtacac atggaagagg accaggacat accacctggg gatgggctga4681 ctcagggtcc cgaggccaga gacaaagctg tgggagccaa gaataagaca gaaggcatca4741 gatatttgcc tggctctggt cacttccctt tgaagttgac ttcaagctta gcttcctcaa4801 ctactgtttt tcagaaggaa gaaagaatca aatggaagaa gaatcaagtc catgcccaag4861 cccaaagcct gcacacattc tgcccttaat ccaagtgttg cctataaaat tattttctgt4921 tttctcactc tagttccccc aaagctgtag tcccaatcaa tcaaaggcta ccaactgagt4981 cctcaggttc atttcttttt tttttttttt tctttttaac tctcctggta actcacagaa5041 cagctcaggt tcatttctag gtgactgtcc taggctactg ctcccccagg agactcaaca5101 ctaaataaag gagtc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>130<211>2436<212>DNA<213>人類(Homo sapiens)<400>1301 atccccgtgt gggggagggg ggccttcggt ctctccccag cctcttcctt ccccctggcc61 tgagggtggg tggggagggg cagttcctct ttccttccca agcaccgagg aggccccagc121 tccctagggg ctgagaagct ggagtcctgg gcaaggggag gagctgagcc ctactcttgc181 aagacccccg gcctcctcac cccacgcggg aagcatgaac agaaaagaca gtaagaggaa241 gtcccaccag gaatgcaccg gaaaaatagg agggcgaggc cggccccgcc aagtgcgccg301 ccacaagaca tgccccagcc ctcgggaaat cagcaaggtc atggcttcca tgaacctggg361 cctgctgagt gagggcggct gcagcgaaga tgagctgctg gagaaatgca tccagtcctt421 cgattcagct ggcagcctgt gccacgagga ccacatgctc aacatggtgc tggccatgca481 cagctgggtg ctgccgtccg ccgacctggc tgcccgcctg ctgacctcat accagaaggc541 cacaggggac acccaggagc tgagacggct gcagatctgt cacctggtca ggtactggct601 gatgcgacac cctgaggtga tgcaccagga tccccagcta gaagaagtca taggtcgttt661 ctgggccacc gtggcccggg agggcaactc agcccagaga agactgggag actcttctga721 cctcctgagc cctggtggcc ctggcccccc actcccaatg agcagcccag gcctgggcaa781 aaagcgcaaa gtgtccttgc ttttcgacca cttggagacg ggggagctgg ctcagcacct841 cacctacctg gagttccggt ccttccaggc tatcacgccc caggacctgc ggagctacgt901 tttgcagggc tcagtacgag gctgcccggc cctggagggc tccgtaggtc tcagcaacag961 cgtgtcccgc tgggtgcagg tgatggtgct gagccgtccc gggcccctac agcgtgcaca1021 ggtgctggac aagttcattc acgtggcaca gaggctccac cagctgcaga atttcaacac1081 gctgatggca gtcacagggg gcctgtgtca cagtgccatc tccagactca aggactccca1141 tgcccacctg agccctgaca gcaccaaggc cctcctggag ctcactgagc tccttgcctc1201 ccacaacaac tacgcccgct accgccgcac ctgggctggc tgcgcgggtt tccggctgcc1261 tgtactgggc gtgcacctca aggacctggt gtccctgcat gaggcacagc ccgacaggtt1321 gcctgacggc cgcctgcacc tacccaagct gaacaacctc tacctgcggc tgcaggagct
1381 ggtggccctc caagggcagc atccaccctg cagcgccaat gaggatctgc tgcacctgct1441 cacgctctcc ctggacctct tctacacgga agacgagatc tatgagcttt cttatgcccg1501 ggagccgcgt tgtcccaaga gcctgccacc ctcccccttc aatgcacctc tggtggtgga1561 gtgggcccct ggtgtgacac ccaagccgga cagggtcaca ctgggtcggc atgtggagca1621 gctggtggag tctgtgttca agaattatga ccctgaaggc cgaggaacaa tctctcagga1681 ggactttgag cgactctcgg gcaattttcc cttcgcctgc catgggcttc acccaccccc1741 acgccagggg agaggatcct tcagcagaga ggagctgaca gggtacctgc tccgggccag1801 cgccatctgc tccaagttgg gcctggcctt cctgcacacc ttccatgagg tcaccttccg1861 aaagcctacc ttctgcgaca gctgcagtgg cttcctctgg ggtgtcacca agcaaggcta1921 ccgctgtcgg gagtgcgggc tgtgttgcca caaacactgc agagaccagg tgaaggtaga1981 atgtaagaag aggccagggg ccaagggcga tgcaggaccc cccggagctc ctgtcccatc2041 cacaccagct ccccatgcca gctgtggctc cgaggaaaat cactcctaca cgctatccct2101 ggagcctgag actgggtgcc agcttcgcca tgcctggacc cagactgaat ccccacaccc2161 ttcctgggaa acagatacgg tcccctgccc ggtgatggac ccaccatcaa ctgcatcctc2221 caagctggat tcctagacat ctcttggtct cctctcttcc tcactccctt cccccagtca2281 gtcctgagtc ctgccgtcag actctggcag ggctcccaga ggtaggcctc cagaggcatc2341 cgccttccca tccacactgc ctttagtggt acgtccgtca tctttttccc tggaagtgac2401 tttcctcttt tgcatcctgg tggatgctaa tcctgc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>131<211>2992<212>DNA<213>人類(Homo sapiens)<400>1311 cagcggggcc cgcattgagc atgggcgcgg cggccgtgcg ctggcacttg tgcgtgctgc61 tggccctggg cacacgcggg cggctggccg ggggcagcgg gctcccaggg tcagtcgacg121 tggatgagtg ctcagagggc acagatgact gccacatcga tgccatctgt cagaacgcgc181 ccaagtccta caaatgcctc tgcaagccag gctacaaggg ggaaggcaag cagtgtggag241 acattgacga gtgtgagaat gactactaca atgggggctg tgtccacgag tgcatcaaca301 tcccggggaa ctacaggtgt acctgctttg atggcttcat gctggcacac gatggacaca361 actgcctgga tgtggacgag tgtcaggaca ataatggtgg ctgccagcag atctgcgtca421 atgccatggg cagctacgag tgtcagtgcc acagtggctt cttccttagt gacaaccagc481 atacctgcat ccaccgctcc aatgagggta tgaactgcat gaacaaagac catggctgtg541 cccacatctg ccgggagacg cccaaaggtg gggtggcctg cgactgcagg cccggctttg601 accttgccca aaaccagaag gactgcacac taacctgtaa ttatggaaac ggaggctgcc661 agcacagctg tgaggacaca gacacaggcc ccacgtgtgg ttgccaccag aagtacgccc721 cccactcaga cggtcgcacg tgcatcgaga cgtgcgcagt caataacgga ggctgcgacc781 ggacatgcaa ggacacagcc actggcgtgc gatgcagctg ccccgttgga ttcacactgc841 agccggacgg gaagacatgc aaagacatca acgagtgcct ggtcaacaac ggaggctgcg901 accacttctg ccgcaacacc gtaggcagct tcgagtgcgg ctgccggaag ggctacaagc961 tgctcaccga cgagcgcacc tgccaggaca tcgacgagtg ctccttcgag cggacctgtg1021 accacatctg catcaactcc ccgggcagct tccagtgcct gtgtcaccgc ggctacatcc1081 tctacgggac aacccactgc ggagatgtgg acgagtgcag catgagcaac gggagctgtg1141 accagggctg cgtcaacacc aagggcagct acgagtgcgt ctgtcccccg gggaggcggc1201 tccactggaa ccggaaggat tgcgtggaga caggcaagtg tctttctcgc gccaagacct
1261 ccccccgggc ccagctgtcc tgcagcaagg caggcggtgt ggagagctgc ttcctttcct1321 gcccggctca cacactcttc gtgccagact cggaaaatag ctacgtcctg agctgcggag1381 ttccagggcc gcagggcaag gcgctgcaga aacgcaacgg caccagctct ggcctcgggc1441 ccagctgctc agatgccccc accaccccca tcaaacagaa ggcccgcttc aagatccgag1501 atgccaagtg ccacctccgg ccccacagcc aggcacgagc aaaggagacc gccaggcagc1561 cgctgctgga ccactgccat gtgactttcg tgaccctcaa gtgtgactcc tccaagaaga1621 ggcgccgtgg ccgcaagtcc ccatccaagg aggtgtccca cattacagca gagtttgaga1681 tcgagacaaa gatggaagag gcctcagaca catgcgaagc ggactgcttg cggaagcgag1741 cagaacagag cctgcaggcc gccatcaaga ccctgcgcaa gtccatcggc cggcagcagt1801 tctatgtcca ggtctcaggc actgagtacg aggtagccca gaggccagcc aaggcgctgg1861 aggggcaggg ggcatgtggc gcaggccagg tgctacagga cagcaaatgc gttgcctgtg1921 ggcctggcac ccacttcggt ggtgagctcg gccagtgtgt gccatgtatg ccaggaacat1981 accaggacat ggaaggccag ctcagttgca caccgtgccc cagcagcgac gggcttggtc2041 tgcctggtgc ccgcaacgtg tcggaatgtg gaggccagtg ttctccaggc ttcttctcgg2101 ccgatggctt caagccctgc caggcctgcc ccgtgggcac gtaccagcct gagcccgggc2161 gcaccggctg cttcccctgt ggagggggtt tgctcaccaa acacgaaggc accacctcct2221 tccaggactg cgaggctaaa gtgcactgct cccccggcca ccactacaac accaccaccc2281 accgctgcat ccgctgcccc gtcggcacct accagcccga gtttggccag aaccactgca2341 tcacctgtcc gggcaacacc agcacagact tcgatggctc caccaacgtc acacactgca2401 aaaaccagca ctgcggcggc gagcttggtg actacaccgg ctacatcgag tcccccaact2461 accctggcga ctacccagcc aacgctgaat gcgtctggca catcgcacct cccccaaagc2521 gcaggatcct catcgtggtc cctgagatct tcctgcccat cgaggatgag tgcggcgatg2581 ttctggtcat gaggaagagt gcctctacca cgtccatcac cacctatgag acctgccaga2641 cctacgagag gcccatcgcc ttcacctccc gctcccgcaa gctctggatc cagttcaaat2701 ccaatgaagg caacagcggc aaaggcttcc aagtgcccta tgtcacctac gatgaggact2761 accagcaact catagaggac atcgtgcgcg atgggcgcct gtacgcctcg gagaaccacc2821 aggaaatttt gaaagacaag aagctgatca aggccctctt cgacgtgctg gcgcatcccc2881 agaactactt caagtacaca gcccaggaat ccaaggagat gttcccacgg tccttcatca2941 aactgctgcg ctccaaagtg tctcggttcc tgcggcccta caaataaccg gg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>132<211>1785<212>DNA<213>人類(Homo sapiens)<400>1321 ccctctgccc gcccccagcc ctcgccccac cctcggcgcc cgcacatctg cctgctcagc61 tccagacggc gcccggaccc ccgggcgcgg gatccagcca ggtgggagcc ccgcagatga121 ggtctctgaa ggtgtgcctg aaccagtgcc agcctgccct gtctgcagca tcggcctgat181 ggggtggtga ctgatccctc agggctccgg agccatgtgg cccaacggca gttccctggg241 gccctgtttc cggcccacaa acattaccct ggaggagaga cggctgatcg cctcgccctg301 gttcgccgcc tccttctgcg tggtgggcct ggcctccaac ctgctggccc tgagcgtgct361 ggcgggcgcg cggcaggggg gttcgcacac gcgctcctcc ttcctcacct tcctctgcgg421 cctcgtcctc accgacttcc tggggctgct ggtgaccggt accatcgtgg tgtcccagca481 cgccgcgctc ttcgagtggc acgccgtgga ccctggctgc cgtctctgtc gcttcatggg541 cgtcgtcatg atcttcttcg gcctgtcccc gctgctgctg ggggccgcca tggcctcaga
601 gcgctacctg ggtatcaccc ggcccttctc gcgcccggcg gtcgcctcgc agcgccgcgc661 ctgggccacc gtggggctgg tgtgggcggc cgcgctggcg ctgggcctgc tgcccctgct721 gggcgtgggt cgctacaccg tgcaataccc ggggtcctgg tgcttcctga cgctgggcgc781 cgagtccggg gacgtggcct tcgggctgct cttctccatg ctgggcggcc tctcggtcgg841 gctgtccttc ctgctgaaca cggtcagcgt ggccaccctg tgccacgtct accacgggca901 ggaggcggcc cagcagcgtc cccgggactc cgaggtggag atgatggctc agctcctggg961 gatcatggtg gtggccagcg tgtgttggct gccccttctg gtcttcatcg cccagacagt1021 gctgcgaaac ccgcctgcca tgagccccgc cgggcagctg tcccgcacca cggagaagga1081 gctgctcatc tacttgcgcg tggccacctg gaaccagatc ctggacccct gggtgtatat1141 cctgttccgc cgcgccgtgc tccggcgtct ccagcctcgc ctcagcaccc ggcccagcgg1201 agtctcactc tgtggcccag cctggagtac agtggcacga tctcggctca ctgcaacctc1261 cgcctcccgg gttcaagcga ttctcgtgcc tcagcctccc gagcagctgg gattacaggc1321 gtaagccact gcgcccggcc ttgcatgctc tttgaccctg aatttgacct acttgctggg1381 gtacagttgc ttccttttga acctccaaca gggaaggctc tgtccagaaa ggattgaatg1441 tgaacggggg cacccccttt tcttgccaaa atatatctct gcctttggtt ttattttcct1501 ttgggtccag aagttttcaa tctctggagt ttgtgcattg ggcctcaccc ggagcagacg1561 agggcagggc tgggaaggat ggggagggac atagaggatt cggttcctcc cccaccttgt1621 ttcttgagtg tttcctaatc acttgatggg tggtaccacc tagaattctt ccagcagcct1681 gtaatgggag ggctacaggt tagccctgga acctgcaatc aaaccacctt tgaatctgtg1741 tgtcattaaa agtagatata aatgggcaaa aaaaaaaaaa aaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>133<211>4434<212>DNA<213>人類(Homo sapiens)<400>1331 gccgccctcg ccaccgctcc cggccgccgc gctccggtac acacaggatc cctgctgggc61 accaacagct ccaccatggg gctggcctgg ggactaggcg tcctgttcct gatgcatgtg121 tgtggcacca accgcattcc agagtctggc ggagacaaca gcgtgtttga catctttgaa181 ctcaccgggg ccgcccgcaa ggggtctggg cgccgactgg tgaagggccc cgacccttcc241 agcccagctt tccgcatcga ggatgccaac ctgatccccc ctgtgcctga tgacaagttc301 caagacctgg tggatgctgt gcggacagaa aagggtttcc tccttctggc atccctgagg361 cagatgaaga agacccgggg cacgctgctg gccctggagc ggaaagacca ctctggccag421 gtcttcagcg tggtgtccaa tggcaaggcg ggcaccctgg acctcagcct gaccgtccaa481 ggaaagcagc acgtggtgtc tgtggaagaa gctctcctgg caaccggcca gtggaagagc541 atcaccctgt ttgtgcagga agacagggcc cagctgtaca tcgactgtga aaagatggag601 aatgctgagt tggacgtccc catccaaagc gtcttcacca gagacctggc cagcatcgcc661 agactccgca tcgcaaaggg gggcgtcaat gacaatttcc agggggtgct gcagaatgtg721 aggtttgtct ttggaaccac accagaagac atcctcagga acaaaggctg ctccagctct781 accagtgtcc tcctcaccct tgacaacaac gtggtgaatg gttccagccc tgccatccgc841 actaactaca ttggccacaa gacaaaggac ttgcaagcca tctgcggcat ctcctgtgat901 gagctgtcca gcatggtcct ggaactcagg ggcctgcgca ccattgtgac cacgctgcag961 gacagcatcc gcaaagtgac tgaagagaac aaagagttgg ccaatgagct gaggcggcct1021 cccctatgct atcacaacgg agttcagtac agaaataacg aggaatggac tgttgatagc1081 tgcactgagt gtcactgtca gaactcagtt accatctgca aaaaggtgtc ctgccccatc
1141 atgccctgct ccaatgccac agttcctgat ggagaatgct gtcctcgctg ttggcccagc1201 gactctgcgg acgatggctg gtctccatgg tccgagtgga cctcctgttc tacgagctgt1261 ggcaatggaa ttcagcagcg cggccgctcc tgcgatagcc tcaacaaccg atgtgagggc1321 tcctcggtcc agacacggac ctgccacatt caggagtgtg acaagagatt taaacaggat1381 ggtggctgga gccactggtc cccgtggtca tcttgttctg tgacatgtgg tgatggtgtg1441 atcacaagga tccggctctg caactctccc agcccccaga tgaacgggaa accctgtgaa1501 ggcgaagcgc gggagaccaa agcctgcaag aaagacgcct gccccatcaa tggaggctgg1561 ggtccttggt caccatggga catctgttct gtcacctgtg gaggaggggt acagaaacgt1621 agtcgtctct gcaacaaccc cacaccccag tttggaggca aggactgcgt tggtgatgta1681 acagaaaacc agatctgcaa caagcaggac tgtccaattg atggatgcct gtccaatccc1741 tgctttgccg gcgtgaagtg tactagctac cctgatggca gctggaaatg tggtgcttgt1801 ccccctggtt acagtggaaa tggcatccag tgcacagatg ttgatgagtg caaagaagtg1861 cctgatgcct gcttcaacca caatggagag caccggtgtg agaacacgga ccccggctac1921 aactgcctgc cctgcccccc acgcttcacc ggctcacagc ccttcggcca gggtgtcgaa1981 catgccacgg ccaacaaaca ggtgtgcaag ccccgtaacc cctgcacgga tgggacccac2041 gactgcaaca agaacgccaa gtgcaactac ctgggccact atagcgaccc catgtaccgc2101 tgcgagtgca agcctggcta cgctggcaat ggcatcatct gcggggagga cacagacctg2161 gatggctggc ccaatgagaa cctggtgtgc gtggccaatg cgacttacca ctgcaaaaag2221 gataattgcc ccaaccttcc caactcaggg caggaagact atgacaagga tggaattggt2281 gatgcctgtg atgatgacga tgacaatgat aaaattccag atgacaggga caactgtcca2341 ttccattaca acccagctca gtatgactat gacagagatg atgtgggaga ccgctgtgac2401 aactgtccct acaaccacaa cccagatcag gcagacacag acaacaatgg ggaaggagac2461 gcctgtgctg cagacattga tggagacggt atcctcaatg aacgggacaa ctgccagtac2521 gtctacaatg tggaccagag agacactgat atggatgggg ttggagatca gtgtgacaat2581 tgccccttgg aacacaatcc ggatcagctg gactctgact cagaccgcat tggagatacc2641 tgtgacaaca atcaggatat tgatgaagat ggccaccaga acaatctgga caactgtccc2701 tatgtgccca atgccaacca ggctgaccat gacaaagatg gcaagggaga tgcctgtgac2761 cacgatgatg acaacgatgg cattcctgat gacaaggaca actgcagact cgtgcccaat2821 cccgaccaga aggactctga cggcgatggt cgaggtgatg cctgcaaaga tgattttgac2881 catgacagtg tgccagacat cgatgacatc tgtcctgaga atgttgacat cagtgagacc2941 gatttccgcc gattccagat gattcctctg gaccccaaag ggacatccca aaatgaccct3001 aactgggttg tacgccatca gggtaaagaa ctcgtccaga ctgtcaactg tgatcctgga3061 ctcgctgtag gttatgatga gtttaatgct gtggacttca gtggcacctt cttcatcaac3121 accgaaaggg acgatgacta tgctggattt gtctttggct accagtccag cagccgcttt3181 tatgttgtga tgtggaagca agtcacccag tcctactggg acaccaaccc cacgagggct3241 cagggatact cgggcctttc tgtgaaagtt gtaaactcca ccacagggcc tggcgagcac3301 ctgcggaacg ccctgtggca cacaggaaac acccctggcc aggtgcgcac cctgtggcat3361 gaccctcgtc acataggctg gaaagatttc accgcctaca gatggcgtct cagccacagg3421 ccaaagacgg gtttcattag agtggtgatg tatgaaggga agaaaatcat ggctgactca3481 ggacccatct atgataaaac ctatgctggt ggtagactag ggttgtttgt cttctctcaa3541 gaaatggtgt tcttctctga cctgaaatac gaatgtagag atccctaatc atcaaattgt3601 tgattgaaag actgatcata aaccaatgct ggtattgcac cttctggaac tatgggcttg3661 agaaaacccc caggatcact tctccttggc ttccttcttt tctgtgcttg catcagtgtg3721 gactcctaga acgtgcgacc tgcctcaaga aaatgcagtt ttcaaaaaca gactcagcat3781 tcagcctcca atgaataaga catcttccaa gcatataaac aattgctttg gtttcctttt3841 gaaaaagcat ctacttgctt cagttgggaa ggtgcccatt ccactctgcc tttgtcacag3901 agcagggtgc tattgtgagg ccatctctga gcagtggact caaaagcatt ttcaggcatg3961 tcagagaagg gaggactcac tagaattagc aaacaaaacc accctgacat cctccttcag
4021 gaacacgggg agcagaggcc aaagcactaa ggggagggcg catacccgag acgattatat4081 gaagaaaata tggaggaact gttacatgtt cggtactaag tcattttaag gggattgaaa4141 gactattgct ggatttcatg atgctgactg gcgttagctg attaacccat gtaaataggc4201 acttaaatag aagcaggaaa gggagacaaa gactggcttc tggacttcct ccctgatccc4261 cacccttact catcacctgc agtggccaga attagggaat cagaatcgaa accagtgtaa4321 ggcagtgctg gctgccattg cctggtcaca ttgaaattgg tggcttcatt ctagatgtag4381 cttgtgcaga tgtagcagga aaataggaaa acctaccatc tcagtgagca ccag<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>134<211>521<212>DNA<213>人類(Homo sapiens)<400>1341 ggacaaggct actataacaa gcctgtgggg caaggtgaat gtggaagatg ctggaggaga61 aaccctggga aggctcctgg ttgtctaccc atggacccag aggttctttg acagctttgg121 caacctgtcc tctgcctctg ccatcatggg caaccccaaa gtcaaggcac atggcaagaa181 ggtgctgact tccttgggag atgccataaa gcacctggat gatctcaagg gcacctttgc241 ccagctgagt gaactgcact gtgacaagct gcatgtggat cctgagaact tcaagctcct301 gggaaatgtg ctggtgaccg ttttggcaat ccatttcggc aaagaattca cccctgaggt361 gcaggcttcc tggcagaaga tggcagaaga tggtgactgg agtggccagt gccctgtcct421 ccagatacta ctgagctcac tgcctatgat gcagagcttt caaggatagg ctttattctg481 caagcaatac aaataataaa tctattctgc taagagatca c<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>135<211>1809<212>DNA<213>人類(Homo sapiens)<400>1351 agaagatcct gggttctgtg catccgtctg tctgaccatc cctctcaatc ttccctgccc61 aggactggcc atactgccac cgcacacgtg cacacacgcc aacaggcatc tgccatgctg121 gcatctctat aagggctcca gtccagagac cctgggccat tgaacttgct cctcaggcag181 aggctgagtc cgcacatcac ctccaggccc tcagaacacc tgccccagcc ccaccatgct241 catggcgtcc accacttccg ctgtgcctgg gcatccctct ctgcccagcc tgcccagcaa301 cagcagccag gagaggccac tggacacccg ggacccgctg ctagcccggg cggagctggc361 gctgctctcc atagtctttg tggctgtggc cctgagcaat ggcctggtgc tggcggccct421 agctcggcgg ggccggcggg gccactgggc acccatacac gtcttcattg gccacttgtg481 cctggccgac ctggccgtgg ctctgttcca agtgctgccc cagctggcct ggaaggccac541 cgaccgcttc cgtgggccag atgccctgtg tcgggccgtg aagtatctgc agatggtggg601 catgtatgcc tcctcctaca tgatcctggc catgacgctg gaccgccacc gtgccatctg661 ccgtcccatg ctggcgtacc gccatggaag tggggctcac tggaaccggc cggtgctagt721 ggcttgggcc ttctcgctcc ttctcagcct gccccagctc ttcatcttcg cccagcgcaa781 cgtggaaggt ggcagcgggg tcactgactg ctgggcctgc tttgcggagc cctggggccg
841 tcgcacctat gtcacctgga ttgccctgat ggtgttcgtg gcacctaccc tgggtatcgc901 cgcctgccag gtgctcatct tccgggagat tcatgccagt ctggtgccag ggccatcaga961 gaggcctggg gggcgccgca ggggacgccg gacaggcagc cccggtgagg gagcccacgt1021 gtcagcagct gtggccaaga ctgtgaggat gacgctagtg attgtggtcg tctatgtgct1081 gtgctgggca cccttcttcc tggtgcagct gtgggccgcg tgggacccgg aggcacctct1141 ggaaggggcg ccctttgtgc tactcatgtt gctggccagc ctcaacagct gcaccaaccc1201 ctggatctat gcatctttca gcagcagcgt gtcctcagag ctgcgaagct tgctctgctg1261 tgcccgggga cgcaccccac ccagcctggg tccccaagat gagtcctgca ccaccgccag1321 ctcctccctg gccaaggaca cttcatcgtg aggagctgtt gggtgtcttg cctctagagg1381 ctttgagaag ctcagctgcc ttcctggggc tggtcctggg agccactggg agggggaccc1441 gtggagaatt ggccagagcc tgtggccccg aggctgggac actgtgtggc cctggacaag1501 ccacagcccc tgcctgggtc tccacatccc cagctgtatg aggagagctt caggccccag1561 gactgtgggg gcccctcagg tcagctcact gagctgggtg taggaggggc tgcagcagag1621 gcctgaggag tggcaggaaa gagggagcag gtgcccccag gtgagacagc ggtcccaggg1681 gcctgaaaag gaaggaccag gctggggcca ggggaccttc ctgtctccgc ctttctaatc1741 cctccctcct cattctctcc ctaataaaaa ttggagctct tttccacatg gcaaggggtc1801 tccttggaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>136<211>1600<212>DNA<213>人類(Homo sapiens)<400>1361 gccccgccgc cggcagtgga ccgctgtgcg cgaaccctga accctacggt cccgacccgc61 gggcgaggcc gggtacctgg gctgggatcc ggagcaagcg ggcgagggca gcgccctaag121 caggcccgga gcgatggcag ccttgatgac cccgggaacc ggggccccac ccgcgcctgg181 tgacttctcc ggggaaggga gccagggact tcccgaccct tcgccagagc ccaagcagct241 cccggagctg atccgcatga agcgagacgg aggccgcctg agcgaagcgg acatcagggg301 cttcgtggcc gctgtggtga atgggagcgc gcagggcgca cagatcgggg ccatgctgat361 ggccatccga cttcggggca tggatctgga ggagacctcg gtgctgaccc aggccctggc421 tcagtcggga cagcagctgg agtggccaga ggcctggcgc cagcagcttg tggacaagca481 ttccacaggg ggtgtgggtg acaaggtcag cctggtcctc gcacctgccc tggcggcatg541 tggctgcaag gtgccaatga tcagcggacg tggtctgggg cacacaggag gcaccttgga601 taagctggag tctattcctg gattcaatgt catccagagc ccagagcaga tgcaagtgct661 gctggaccag gcgggctgct gtatcgtggg tcagagtgag cagctggttc ctgcggacgg721 aatcctatat gcagccagag atgtgacagc caccgtggac agcctgccac tcatcacagc781 ctccattctc agtaagaaac tcgtggaggg gctgtccgct ctggtggtgg acgttaagtt841 cggaggggcc gccgtcttcc ccaaccagga gcaggcccgg gagctggcaa agacgctggt901 tggcgtggga gccagcctag ggcttcgggt cgcggcagcg ctgaccgcca tggacaagcc961 cctgggtcgc tgcgtgggcc acgccctgga ggtggaggag gcgctgctct gcatggacgg1021 cgcaggcccg ccagacttaa gggacctggt caccacgctc gggggcgccc tgctctggct1081 cagcggacac gcggggactc aggctcaggg cgctgcccgg gtggccgcgg cgctggacga1141 cggctcggcc cttggccgct tcgagcggat gctggcggcg cagggcgtgg atcccggtct1201 ggcccgagcc ctgtgctcgg gaagtcccgc agaacgccgg cagctgctgc ctcgcgcccg1261 ggagcaggag gagctgctgg cgcccgcaga tggcaccgtg gagctggtcc gggcgctgcc
1321 gctggcgctg gtgctgcacg agctcggggc cgggcgcagc cgcgctgggg agccgctccg1381 cctgggggtg ggcgcagagc tgctggtcga cgtgggtcag aggctgcgcc gtgggacccc1441 ctggctccgc gtgcaccggg acggccccgc gctcagcggc ccgcagagcc gcgccctgca1501 ggaggcgctc gtactctccg accgcgcgcc attcgccgcc ccctcgccct tcgcagagct1561 cgttctgccg ccgcagcaat aaagctcctt tgccgcgaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>137<211>2048<212>DNA<213>人類(Homo sapiens)<400>1371 ctattgatct ggactcctgg ataggcagct ggaccaacgg acggacgcca tgagggctct61 gctgctcctg gggttcctgc tggtgagctt ggagtcaaca ctttcgattc caccttggga121 agcccccaag gagcataagt acaaagctga agagcacaca gtcgttctca ctgtcaccgg181 ggagccctgc cacttcccct tccagtacca ccggcagctg taccacaaat gtacccacaa241 gggccggcca ggccctcagc cctggtgtgc taccaccccc aactttgatc aggaccagcg301 atggggatac tgtttggagc ccaagaaagt gaaagaccac tgcagcaaac acagcccctg361 ccagaaagga gggacctgtg tgaacatgcc aagcggcccc cactgtctct gtccacaaca421 cctcactgga aaccactgcc agaaagagaa gtgctttgag cctcagcttc tccggttttt481 ccacaagaat gagatatggt atagaactga gcaagcagct gtggccagat gccagtgcaa541 gggtcctgat gcccactgcc agcggctggc cagccaggcc tgccgcacca acccgtgcct601 ccatgggggt cgctgcctag aggtggaggg ccaccgcctg tgccactgcc cggtgggcta661 caccggaccc ttctgcgacg tggacaccaa ggcaagctgc tatgatggcc gcgggctcag721 ctaccgcggc ctggccagga ccacgctctc gggtgcgccc tgtcagccgt gggcctcgga781 ggccacctac cggaacgtga ctgccgagca agcgcggaac tggggactgg gcggccacgc841 cttctgccgg aacccggaca acgacatccg cccgtggtgc ttcgtgctga accgcgaccg901 gctgagctgg gagtactgcg acctggcaca gtgccagacc ccaacccagg cggcgcctcc961 gaccccggtg tcccctaggc ttcatgtccc actcatgccc gcgcagccgg caccgccgaa1021 gcctcagccc acgacccgga ccccgcctca gtcccagacc ccgggagcct tgccggcgaa1081 gcgggagcag ccgccttccc tgaccaggaa cggcccactg agctgcgggc agcggctccg1141 caagagtctg tcttcgatga cccgcgtcgt tggcgggctg gtggcgctac gcggggcgca1201 cccctacatc gccgcgctgt actggggcca cagtttctgc gccggcagcc tcatcgcccc1261 ctgctgggtg ctgacggccg ctcactgcct gcaggaccgg cccgcacccg aggatctgac1321 ggtggtgctc ggccaggaac gccgtaacca cagctgtgag ccgtgccaga cgttggccgt1381 gcgctcctac cgcttgcacg aggccttctc gcccgtcagc taccagcacg acctggctct1441 gttgcgcctt caggaggatg cggacggcag ctgcgcgctc ctgtcgcctt acgttcagcc1501 ggtgtgcctg ccaagcggcg ccgcgcgacc ctccgagacc acgctctgcc aggtggccgg1561 ctggggccac cagttcgagg gggcggagga atatgccagc ttcctgcagg aggcgcaggt1621 accgttcctc tccctggagc gctgctcagc cccggacgtg cacggatcct ccatcctccc1681 cggcatgctc tgcgcagggt tcctcgaggg cggcaccgat gcgtgccagg gtgattccgg1741 aggcccgctg gtgtgtgagg accaagctgc agagcgccgg ctcaccctgc aaggcatcat1801 cagctgggga tcgggctgtg gtgaccgcaa caagccaggc gtctacaccg atgtggccta1861 ctacctggcc tggatccggg agcacaccgt ttcctgattg ctcagggact catctttccc1921 tccttggtga ttccgcagtg agagagtggc tggggcatgg aaggcaagat tgtgtcccat1981 tcccccagtg cggccagctc cgcgccagga tggcgaggaa ctcaataaag tgctttgaaa
2041 atgctgag<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>138<211>955<212>DNA<213>人類(Homo sapiens)<400>1381 agtaagccgg gctgccgtct tctcgccatg ggctccgggc cgcgcggggc gctgagctta61 ctgctcctgc tgctggcccc gccgagccgc ccggccgcag gttgcccggc gccctgtagc121 tgcgcgggga cgctcgtgga ctgcgggcgc cgcgggctga cttgggcctc gctgccgacc181 gccttccctg tcgacacaac cgagctggtg ctgaccggca acaacctgac ggcgctgccg241 ccggggctgc tggacgcgct gcccgcgctg cgcaccgcac acctgggcgc caacccctgg301 cgctgcgact gccgccttgt gccgctgcgc gcctggctgg ccggccgccc cgagcgtgcg361 ccctaccgcg acctgcgttg cgtggcgccc ccagcgctgc gcggccgcct gctgccctat421 ctggccgagg acgagctgcg cgccgcttgc gctcccggcc cgctctgctg gggggcgctg481 gcggcgcagc ttgcgctgct gggccttggg ctgctgcacg cgttgctgct ggtgctgctg541 ctgtgccgcc tgcggaggct gcgggcccgg gcccgcgctc gcgccgcagc ccggctgtcg601 ctgaccgacc cgctggtggc cgagcgagcc ggaaccgacg agtcctgagg agagaaccgg661 tgcgtcctga ggagagaacc ggcgctgggc aacacgggcc tgcaaactcg acaggaccct721 gcccgagggg ccctcgcgcc aacctggacc ggtccccgcc tcctccgctg cccaatctct781 cagacccacc ccacctgcag gcccagacca cgtgggacag aactcctgcc caccctaccc841 cgagggaggc gaacccgcac ttccaggctt gggaggacca tggggcacaa tgcggtccag901 accctgctgc gtctcccttc caaactctgg tgctgaataa acccttctga tctgg<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>139<211>900<212>DNA<213>人類(Homo sapiens)<400>1391 gccaggacct ttcaggccag acaggagcac ctgaccaaag gcttcacagc cgccctcacc61 gcccggcctt ctacggtgtc cagagacagt tagccaggcc tgggctgggc acactccacc121 ttccctagtc accagctggt ttcccagagg agaaggctga gacccgagaa gggagccagc181 ctgtcccatg cctgcctggg gagccctgtt cctgctctgg gccacagcag aggccaccaa241 ggactgcccc agcccatgta cctgccgcgc cctggaaacc atggggctgt gggtggactg301 caggggccac ggactcacgg ccctgcctgc cctgccggcc cgcacccgcc accttctgct361 ggccaacaac agccttcagt ccgtgccccc gggagccttt gaccacctgc cccagctgca421 gaccctcgat gtgacgcaga acccctggca ctgtgactgc agcctcacct atctgcgcct481 ctggctggag gaccgcacgc ccgaggccct gctgcaggtc cgctgtgcca gccccagcct541 cgctgcccat ggcccgctgg gccggctgac aggctaccag ctgggcagct gtggctggca601 gctgcaggcg tcctgggtgc gcccgggggt cttgtgggac gtggcgctgg tcgccgtggc661 cgcgctgggc ctggctcttc tggctggcct gctgtgtgcc accacagagg ccctggattg721 agccaggccc ccagaacccc tggctccagg ccagggggcc agtccctgag gcaggtcccc
781 agactccacc aagcctggtc agcccaaacc accagaagcc cagaataaac tggcagctca841 gctgttttat ataaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>140<211>576<212>DNA<213>人類(Homo sapiens)<400>1401 actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa61 gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga121 ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga181 cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac241 caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca301 cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt361 gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa421 gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt481 ggccatgctt cttgcccctt gggcctcccc ccagcccctcc tccccttcc tgcacccgta541 cccccgtggt ctttgaataa agtctgagtg ggcggc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>141<211>575<212>DNA<213>人類(Homo sapiens)<400>1411 actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa61 gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga121 ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga181 cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac241 caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca301 cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt361 gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa421 gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt481 agccgttcct cctgcccgct gggcctccca acgggccctc ctcccctcct tgcaccggcc541 cttcctggtc tttgaataaa gtctgagtgg gcggc<110>同濟大學附屬同濟醫(yī)院<120>肺血栓栓塞癥相關基因及其應用<160>142<210>142<211>147<212>DNA<213>人類(Homo sapiens)
<400>1421 gaatgtggca aagcctttaa cagttctcaa atcttaccta cacataaaaa aattcataat61 ggagagcaac cctacatatg tgaagaatgt gtgaaatttt ttacccaatc ctcaaccctt121 actacacata agagaattca tactgag
權利要求
1.一組與肺血栓栓塞癥相關的基因，其特征在于具有如SEQ ID NO1、SEQ ID NO2、SEQ ID NO3、SEQ ID NO4、SEQ ID NO5、SEQ IDNO6、SEQ ID NO7、SEQ ID NO8、SEQ ID NO9、SEQ ID NO10、SEQ ID NO11、SEQ ID NO12、SEQ ID NO13、SEQ ID NO14、SEQID NO15、SEQ ID NO16、SEQ ID NO17、SEQ ID NO18、SEQ IDNO19、SEQ ID NO20、SEQ ID NO21、SEQ ID NO22、SEQ ID NO23、SEQ ID NO24、SEQ ID NO25、SEQ ID NO26、SEQ ID NO27、SEQ ID NO28、SEQ ID NO29、SEQ ID NO30、SEQ ID NO31、SEQID NO32、SEQ ID NO33、SEQ ID NO34、SEQ ID NO35、SEQ IDNO36、SEQ ID NO37、SEQ ID NO38、SEQ ID NO39、SEQ ID NO40、SEQ ID NO41、SEQ ID NO42、SEQ ID NO43、SEQ ID NO44、SEQ ID NO45、SEQ ID NO46、SEQ ID NO47、SEQ ID NO48、SEQID NO49、SEQ ID NO50、SEQ ID NO51、SEQ ID NO52、SEQ IDNO53、SEQ ID NO54、SEQ ID NO55、SEQ ID NO56、SEQ ID NO57、SEQ ID NO58、SEQ ID NO59、SEQ ID NO60、SEQ ID NO61、SEQ ID NO62、SEQ ID NO63、SEQ ID NO64、SEQ ID NO65、SEQID NO66、SEQID NO67、SEQ ID NO68、SEQ ID NO69、SEQ IDNO70、SEQ ID NO71、SEQ ID NO72、SEQ ID NO73、SEQ ID NO74、SEQ ID NO75、SEQ ID NO76、SEQ ID NO77、SEQ ID NO78、SEQ ID NO79、SEQ ID NO80、SEQ ID NO81、SEQ ID NO82、SEQID NO83、SEQ ID NO84、SEQ ID NO85、SEQ ID NO86、SEQ IDNO87、SEQ ID NO88、SEQ ID NO89、SEQ ID NO90、SEQ ID NO91、SEQ ID NO92、SEQ ID NO93、SEQ ID NO94、SEQ ID NO95、SEQ ID NO96、SEQ ID NO97、SEQ ID NO98、SEQ ID NO99、SEQID NO100、SEQ ID NO101、SEQ ID NO102、SEQ ID NO103、SEQID NO104、SEQ ID NO105、SEQ ID NO106、SEQ ID NO107、SEQID NO108、SEQ ID NO109、SEQ ID NO110、SEQ ID NO111、SEQID NO112、SEQ ID NO113、SEQ ID NO114、SEQ ID NO115、SEQID NO116、SEQ ID NO117、SEQ ID NO118、SEQ ID NO119、SEQID NO120、SEQ ID NO121、SEQ ID NO122、SEQ ID NO123、SEQID NO124、SEQ ID NO125、SEQ ID NO126、SEQ ID NO127、SEQID NO128、SEQ ID NO129、SEQ ID NO130、SEQ ID NO131、SEQID NO132、SEQ ID NO133、SEQ ID NO134、SEQ ID NO135、SEQID NO136、SEQ ID NO137、SEQ ID NO138、SEQ ID NO139、SEQID NO140、SEQ ID NO141和SEQ ID NO142所示的全長基因。
2.如權利要求1所述的肺血栓栓塞癥相關的基因在制備診斷肺血栓栓塞癥的試劑盒中的應用。
全文摘要
本發(fā)明公開了一組與肺血栓栓塞癥相關基因，以及肺血栓栓塞癥相關基因制備診斷肺血栓栓塞癥試劑中的應用。本發(fā)明利用基因芯片技術，為診斷肺血栓栓塞癥提供了一種新的方法。
文檔編號C12Q1/68GK1986793SQ20051011164
公開日2007年6月27日 申請日期2005年12月19日 優(yōu)先權日2005年12月19日
發(fā)明者王樂民 申請人:同濟大學附屬同濟醫(yī)院